Brilliant Violet 510™ anti-mouse CD4 100449 from BioLegend

Product Specs
ItemBrilliant Violet 510™ anti-mouse CD4
CompanyBioLegend
Price $274.00Supplier Page View Company Product Page
Catalog Number100449
Quantity50 µg
ApplicationsFC - Quality tested
Concentration0.2mg/ml
Conjugate/TagBrilliant Violet 510™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityMouse
IsotypeRat IgG2b, kappa
CloneGK1.5
HostRat
Antibody TypePrimary
ImmunogenMouse CTL clone V4
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) B cell CD19 is transferred between immune cells in mice and humansNat CommunJuly 29, 2026Jasmin Ochs, Pia Schweineberg, Jacqueline Thode, Alica Blenkle, Leila Husseini, Matthias Klein, Tobias Bopp, Patrick Schindler, Friedemann Paul, Martin S. WeberBioLegend; #100308, #100306, #100351; BD Biosciences; #563565), CD4-BV510 or FITC (GK1.5; BioLegend; #100449, #100406), CD8-BV421, FITC or PerCP-Cy5.5 (53-6.7; BioLegend; #100738, #100706, #100734), CD45R/B220-PE-CY7

(2) Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 BlockadeAdvanced ScienceJune 2, 2026Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, et al.(FITC, BioLegend, Clone 145‐2C11, Cat# 100306), CD4 (Brilliant Violet 510, BioLegend, Clone RM4‐5, Cat# 100449), CD8a (Brilliant Violet 421, BioLegend, Clone 53‐6.7, Cat# 100753), CD25 (APC, BioLegend, Clone PC61,

(3) A CD4+ T cell-fibroblast crosstalk exacerbates autoimmunity in a mouse model of primary Sjögren diseaseNature CommunicationsMay 12, 2026Kunihiro Otsuka, Hiroyuki Kondo, Shin-Ichi Tsukumo, Daisuke Kurotaki, Kei-ichiro Yasunaga, Aya Ushio, Ruka Nagao, Keiko Aota, Yoshiaki Kitamura, Takaaki Tsunematsu, et al.(RM153, BioLegend, Cat# 106409), Brilliant Violet 510-conjugated anti-mouse CD4 (GK1.5, BioLegend, Cat# 100449), and Pacific Blue-conjugated anti-mouse CD8α (53-6.7, BioLegend, Cat# 100725) antibodies. Details of

(4) β-oxidation-mediated differentiation of effector CD4+ T cells in the lung enhances neuroinflammationJournal of NeuroinflammationMay 9, 2026Qianling Jiang, Gaochen Zhu, Xin Ma, Wen Si, Guan Yang103112), CD11b (BioLegend, 101235), Ly6C (BioLegend, 128033), Ly6G (BioLegend, 127618), CD4 (Biolegend, 100449), CD44 (Biolegend, 103005), CD62L (Biolegend, 104417), CD8 (Biolegend, 100751), CD19 (Biolegend, 115529),

(5) Vaccinia virus armed with IL-21 can cure murine colorectal cancer liver metastases via intravenous administrationJ Immunother CancerMarch 25, 2026Na Wang, Yijia He, Junzhi Yu, Yimeng Xia, Yangyang Jia, Ruixian Liu, Yanru Zhang, Yan Liu, Shiyang Ning, Louisa S Chard Dunmall, et al.103130), CD3-PE/Cyanine7 (BioLegend, 100220), CD8a-FITC (BioLegend, 100706), CD4-BV510 (BioLegend, 100449), CD62L-PE (BioLegend, 100408), CD44-APC (BioLegend, 103012), CD127-BV711 (BioLegend, 135035), CD25-BV421

(6) Drug-free Immunotherapeutic Biomimetic Nanoparticles for Treating Triple-Negative Breast CancerACS NanoMarch 3, 2026Ofri Vizenblit, Rawan Mhajne, Assaf Zinger(BLG-128008), anti-CD3-Spark Blue 574 (BLG-100276), anti-CD8a-Alexa Fluor 594 (BLG-100758), anti-CD4-BV510 (BLG-100449), anti-FoxP3-Pacific Blue (BLG-126410), anti-CD19-PE-Cy7 (BLG-152418), and Zombie Violet Viability Kit

(7) Pharmacological perturbation of splicing elicits SMG1 reduction: Implications for cancer therapyiScienceFebruary 20, 2026Martin Barainka, Angelina Zheleva, Angela Pérez-Cervera, Helena Villanueva, Daniel Meraviglia-Crivelli, Beatriz Moreno, Fernando PastorAPC/Fire 750 anti-mouse CD8a,BioLegend,"Cat#100765, RRID:AB_2572112" Brilliant Violet 510 anti-mouse CD4,BioLegend,"Cat#100449, RRID:AB_2564587" APC anti-mouse CD25,BioLegend,"Cat#102012, RRID:AB_312861" Alexa Fluor 700 anti-mouse/human CD11b

(8) Neutrophil-microglia interaction drives motor dysfunction in a neuromyelitis optica model induced by subarachnoid AQP4-IgGJ Clin InvestFebruary 10, 2026Fangfang Qi, Vanda A. Lennon, Shunyi Zhao, Yong Guo, Husheng Ding, Caiyun Liu, Whitney M. Bartley, Tingjun Chen, Claudia F. Lucchinetti, Long-Jun Wu117334, clone n418, 1:200), CD3-PE/Fire700 (BioLegend, 100272, clone 17A2, 1:200), CD4-BV510 (BioLegend, 100449, clone GK1.5, 1:200), CD8a-BV785 (BioLegend, 100750, clone 53-6.7, 1:200), CX3CR1-Pacific Blue (BioLegend,

(9) Neutrophil-microglia interaction drives motor dysfunction in a neuromyelitis optica model induced by subarachnoid AQP4-IgGJournal of Clinical InvestigationFebruary 10, 2026Fangfang Qi, Vanda A. Lennon, Shunyi Zhao, Yong Guo, Husheng Ding, Caiyun Liu, Whitney M. Bartley, Tingjun Chen, Claudia F. Lucchinetti, Long-Jun Wu117334, clone n418, 1:200), CD3-PE/Fire700 (BioLegend, 100272, clone 17A2, 1:200), CD4-BV510 (BioLegend, 100449, clone GK1.5, 1:200), CD8a-BV785 (BioLegend, 100750, clone 53-6.7, 1:200), CX3CR1-Pacific Blue (BioLegend,

(10) Single-cell RNA sequencing unveils enhanced antitumor immunity in colorectal cancer with PD-1 blockade and LINC00673 deletionBiomarker ResearchJanuary 3, 2026Yifei Zhu, Yanxi Yao, Yaxian Wang, Zhibing Qiu, Dingpei Zhou, Huixia Huang, Keji Chen, Qingyang Sun, Jiayu Chen, Yuxue Li, et al.San Diego, CA, USA), FITC anti-mouse CD3ε(100306, BioLegend), Brilliant Violet 510™ anti-mouse CD4 (100449, BioLegend), APC anti-mouse CD25 (102012, BioLegend), Alexa Flour 700 anti-mouse FOXP3 (126422, BioLegend), Brilliant Violet

(11) Newly identified oncolytic VSV-GP-specific CD8+ T cell epitopes for monitoring of anti-viral immune responses in the BALB/c mouse modelMolecular Therapy OncologyDecember 18, 2025Sarah Danklmaier, Saskia V. Vijver, Lisa Pipperger, Gabriel Floriani, Lukas Perro, Vanessa Konrad, Tamara Hofer, Hubert Hackl, Krishna Das, Guido Wollmann(BioLegend #109828), anti-mouse CD8a-BV421 (BD Biosciences #563898), anti-mouse CD4-BV510 (BioLegend #100449), anti-mouse CD45.2-AF488 (BioLegend #109816), anti-mouse CD90.2-AF700 (BioLegend #105320), anti-mouse

(12) Neutrophil-microglia interaction drives reversible motor dysfunction in neuromyelitis optica model induced by subarachnoid AQP4-IgGbioRxivSeptember 2, 2025Fangfang Qi, Vanda A. Lennon, Shunyi Zhao, Yong Guo, Husheng Ding, Caiyun Liu, Whitney M. Bartley, Tingjun Chen, Claudia F. Lucchinetti, Long-Jun Wu1:1,000), CD11b-PE-Cy5 (Tonbo, 55-0112-U100, 1:1,000), CD11c (BioLegend, 1:200), CD4-BV510 (BioLegend, 100449, 1:200), CD8a-BV785(BioLgend, 100750, 1:200), CX3CR1-Pacific Blue (BioLegend, 149038, 1:300), CD206

(13) Gold-siRNA supraclusters enhance the anti-tumor immune response of stereotactic ablative radiotherapy at primary and metastatic tumorsNature BiotechnologySeptember 1, 2025Yuyan Jiang, Hongbin Cao, Huaping Deng, Li Guan, Jimpi Langthasa, Deana Rae Crystal Colburg, Stavros Melemenidis, Renee M. Cotton, John Aleman, Xiao-Jing Wang, et al.BioLegend, 103147), BV421-TCRb (dilution 1:200; BioLegend, 109229), BV510-CD4 (dilution 1:200; BioLegend, 100449), PE/Cy7-CD8a (dilution 1:200; BioLegend, 100721), APC-CD11b (dilution 1:200; BioLegend, 101211), PE-Ly6G

(14) Nanofilament immunotherapy induces potent antitumor vaccine responsesJournal for immunotherapy of cancerAugust 31, 2025Neil K, Génier S, Poisson MÈ, Douchin J, Giguère H, Daniel L, Gonzalez MF, Huang S, Trinh VQ, Tai LH, et al.(#12-0251-82), anti-CD45-AF700 (#56-0454-82), anti-CD19-APC (#17-0193-80), and from BioLegend: anti-CD4-BV510 (#100449). Antibody-cell mixtures were incubated for 30 min at 4°C and washed twice in FACS buffer before resuspension

(15) CD138 and APRIL regulate plasma cell survival, competition, and retention in the bone marrow nicheCell ReportsAugust 26, 2025Rosa Park, Zachary Benet, Zhixin Jing, Jennifer Enright, David R. Fooksman17A2),BioLegend,Cat# 100246; RRID:AB_2565883 Rat monoclonal anti-CD4 BV510 (clone GK1.5),BioLegend,Cat# 100449; RRID:AB_2564587 Rat monoclonal anti-CD8alpha BV510 (clone 53–6.7),BioLegend,Cat# 100752; RRID:AB_2563057 Rat

(16) Ferroptosis-disulfidptosis-related CHMP6 is a clinico-immune target in colorectal cancerBiol DirectJuly 21, 2025Yifei Zhu, Huixia Huang, Jiayu Chen, Keji Chen, Yanxi Yao, Yaxian Wang, Yuxue Li, Zhibing Qiu, Dawei Li, Ping Weidensity of 1 × 106 cells/100 µL. The cells were first blocked with Brilliant Violet 510™ anti-mouse CD4 (100449, BioLegend), Alexa Flour 700 anti-mouse FOXP3 (126422, BioLegend), Brilliant Violet 421™ anti-mouse

(17) Engineered Endosymbionts that Modulate Primary Macrophage Function and Attenuate Tumor Growth by Shifting the Tumor MicroenvironmentACS Applied Bio MaterialsJuly 21, 2025Cody S. Madsen, Ashley V. Makela, Chima V. Maduka, Emily M. Greeson, Anthony Tundo, Evran Ural, Satyajit Hari Kulkarni, Ahmed A. Zarea, Matti Kiupel, Maryam Sayadi, et al.Ly-6G Alexa Fluor 700 (1:200; Biolegend, cat#127621), CD4 Brilliant Violet 510 (1:300; Biolegend, cat#100449), MHC-II (I-A/I-E) Spark Blue 550 (0.25 μg/sample; Biolegend, cat#107661), CD206 BV421 (1.25 μL/sample;

(18) Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation caused by co-infection or colitis in miceNature MicrobiologyJuly 8, 2025Aline Sardinha-Silva, Pedro H. Gazzinelli-Guimaraes, Oluwaremilekun G. Ajakaye, Fabricio M. S. Oliveira, Tiago R. Ferreira, Eliza V. C. Alves-Ferreira, Erick T. Tjhin, Beth Gregg, Marc Y. Fink, Camila H. Coelho, et al.BV421",Biolegend,Cat #139309; RRID: AB_2562694 "Anti-mouse CD4 (clone GK1.5), BV510",Biolegend,Cat #100449; RRID: AB_2564587 "Anti-mouse CD11b (clone M1/70), BV605",Biolegend,Cat #101257; RRID: AB_2565431 "Anti-mouse

(19) Folate metabolism-associated CYP26A1 is a clinico-immune target in colorectal cancerGenes & ImmunityJuly 3, 2025Yifei Zhu, Teng Zhou, Yao Zheng, Yanxi Yao, Mingxi Lin, Cheng Zeng, Yuxin Yan, Yifei Zhou, Dou-Dou Li, Jian Zhangdensity of 1 × 106 cells/100 μL. The cells were first blocked with Brilliant Violet 510™ anti-mouse CD4 (100449, BioLegend), Alexa Flour 700 anti-mouse FOXP3 (126422, BioLegend), Brilliant Violet 421™ anti-mouse

(20) Somatic hypermutation generates antibody specificities beyond the primary repertoireImmunityJune 10, 2025Teng Zuo, Avneesh Gautam, Shahab Saghaei, Sweta N. Khobragade, Rahaman Ahmed, Azadeh Mahdavinia, Mehrdad Zarghami, Gaspar A. Pacheco, Kenneth Green, Meghan Travers, et al.CD45.2 PE [104],BioLegend,Cat# 109807; RRID: AB_313444 Anti-mouse CD4 BV510 [GK1.5],BioLegend,Cat# 100449; RRID: AB_2564587 Anti-mouse CD8a BV510 [53-6.7],BioLegend,Cat# 100752; RRID: AB_ 2563057 Anti-mouse

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(1)

6/8/2023Ok Anti-Mouse CD4 BV510 Antibody from BioLegendDr. Andreia LinoAntibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in ... Read Review
(1)

4/26/2021Great CD4+ Staining Robert YuanWe wanted to examine CD4+ T cells in the healthy vs diseased state, so we used this antibody to identify CD4+ T cells in the blood.
(1)

3/14/2017Okay Antibody To Stain For Mouse CD4+ T Cells Kevin MengSuccessfully detects CD4+ T cells in thymus, spleen, and lymph node with good signal but comes with some background.

Brilliant Violet 510™ anti-mouse CD4 from BioLegend

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Brilliant Violet 510™ anti-mouse CD4 from BioLegend

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