α-Actin (a-SM1) Antibody sc-130616 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemα-Actin (a-SM1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-130616
Antibody TypePrimary Antibodies
NCBI Gene AliasesalphaSMA, 0610041G09Rik, Actvs, ACTSA, a-SMA, SMalphaA, SMAalpha
Clonea-SM1
Quantity200 µg/ml
FormatPurified
Hostmouse
Reactivitymouse, rat, human
ClonalityMonoclonal
ApplicationsWB, IP, IF, IHC(P), ELISA
Conjugate/TagUnconjugated
NCBI Full Gene Nameactin alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle
Targetsmooth muscle alpha-Actin
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Atorvastatin Attenuates Human Cardiac Fibroblast Activation, with Associated Changes in GATA4/MEF2C and Selected Fibrosis-Related microRNAsInt J Mol SciMay 6, 2026Nikola Chomaničová, Adriana Adamičková, Zdenko Cervenak, Simona Valášková, Andrea Gažová, Jan KyselovicSigma-Aldrich) for 1 h, cells were incubated with primary antibodies against α-SMA (1:100 dilution, Cat# sc-130616, Santa Cruz Biotechnology, Dallas, Texas, USA), MEF2C (1:200 dilution, Cat# D80C1 XP®, Cell Signaling,

(2) Physiological role and mechanisms of action for a long noncoding haplotype regionCell ReportsJune 24, 2025Hong Xue, Manoj K. Mishra, Yong Liu, Pengyuan Liu, Michael Grzybowski, Rajan Pandey, Kristie Usa, Mark A. Vanden Avond, Niharika Bala, Abdel A. Alli, et al.AF938, R&D Systems) primary antibodies. For vascular smooth muscle cells, anti-human α-SMA (1:200, sc-130616, Santa Cruz Biotechnology) or Myosin IIb (1:200, 8824S, Cell Signaling Technology) primary antibodies

(3) Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cellsScientific reportsSeptember 12, 2023Souralova T, Hulinova D, Jeseta M, Ventruba P, Hampl A, Koutna I.anti-SOX2 at 1:100 dilution (cat: MAB2018, R&D Systems), mouse anti-α-actin at 1:200 dilution (cat: sc-130616, Santa Cruz Biotechnology), goat anti-FOXA2 at 1:200 dilution (cat: AF2400, R&D Systems), mouse anti-β3

(4) Comparative study of differentiating human pluripotent stem cells into vascular smooth muscle cells in hydrogel-based culture methodsRegenerative therapyMarch 1, 2023Liu Q, Liu Z, Gu H, Ge Y, Wu X, Zuo F, Du Q, Lei Y, Wang Z, Lin H.30 min, and blocked with 5% donkey serum for 1 h before incubating with primary antibodies: α-SMA (sc-130616, Santa Cruz), SM22A (ab14106, Abcam), Human-PDGFRB (PA5-14718, ThermoFisher), Human-CD31 (555444, BD Biosciences

(5) Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy-induced toxicitiesScience advancesNovember 11, 2022Spetz JKE, Florido MHC, Fraser CS, Qin X, Choiniere J, Yu SJ, Singh R, Friesen M, Rubin LL, Salem JE, et al.phalloidin (Thermo Fisher Scientific, catalog no. A12379), and αSMA (Santa Cruz Biotechnology, catalog no. sc-130616). For tissue samples from irradiated or BH3 mimetic–treated mice, tissue samples were fixed in Davidson’s

(6) The Manufacture of Xeno- and Feeder-Free Clinical-Grade Human Embryonic Stem Cell Lines: First Step for Cell TherapyInternational journal of molecular sciencesOctober 18, 2022Souralova T, Rehakova D, Jeseta M, Tesarova L, Beranek J, Ventruba P, Hampl A, Koutna I.Cell Signaling Technology), mouse anti-Sox2, 1:100 (cat: MAB2018, R&D Systems), mouse anti-α-actin, 1:200 (cat: sc-130616, Santa Cruz Biotechnology), goat anti-FOXA2, 1:200 (cat: AF2400, R&D Systems), mouse anti-β3 Tubulin,

(7) Xeno- and feeder-free derivation of two sex-discordant sibling lines of human embryonic stem cellsStem cell researchDecember 1, 2021Souralova T, Holubcova Z, Kyjovska D, Hampl A, Koutna I.

(8) Ceramide in apoptosis and oxidative stress in allergic inflammation and asthmaThe Journal of allergy and clinical immunologyMay 1, 2021James BN, Oyeniran C, Sturgill JL, Newton J, Martin RK, Bieberich E, Weigel C, Maczis MA, Palladino END, Lownik JC, et al.

(9) Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis TherapyMaterials (Basel)November 6, 2020Simona-Rebeca Ignat, Sorina Dinescu, Judit Váradi, Ferenc Fenyvesi, Thi Le Phuong Nguyen, Alina Ciceu, Anca Hermenean, Marieta Costachesolution with 0.1% Triton X100. Overnight at 4 ◦ C, samples were incubated with antibody anti-α-sma (sc-130616, Santa Cruz Biotechnology), and then incubated for 1 h with antibody anti-mouse conjugated with fluorescein

(10) A coagulation defect arising from heterozygous premature termination of tissue factorThe Journal of clinical investigationOctober 1, 2020Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, et al.

(11) Autologously transplanted dermal fibroblasts improved diabetic wound in rat modelActa histochemicaJuly 1, 2020Mutlu HS, Erdoğan A, Tapul L.

(12) Generation of three induced pluripotent stem cell lines (MHHi012-A, MHHi013-A, MHHi014-A) from a family with Loeys-Dietz syndrome carrying a heterozygous p.M253I (c.759G>A) mutation in the TGFBR1 geneStem cell researchMarch 1, 2020Pongpamorn P, Dahlmann J, Haase A, Ebeling CT, Merkert S, Göhring G, Lachmann N, Martens A, Haverich A, Martin U, et al.

(13) S100B is required for maintaining an intermediate state with double-positive Sca-1+ progenitor and vascular smooth muscle cells during neointimal formationStem cell research & therapySeptember 23, 2019Wu Y, Liu X, Guo LY, Zhang L, Zheng F, Li S, Li XY, Yuan Y, Liu Y, Yan YW, et al.co-immunofluorescent staining, the artery sections from different time points were incubated with α-SMA (sc-130616, Santa Cruz, 1:100) and SDF-1α (ab9797, Abcam, 1:100) antibodies followed by fluorescent dye-conjugated

(14) Cellular and morphological changes with EAA supplementation before and after total knee arthroplastyJournal of applied physiology (Bethesda, Md. : 1985)August 1, 2019Muyskens JB, Foote DM, Bigot NJ, Strycker LA, Smolkowski K, Kirkpatrick TK, Lantz BA, Shah SN, Mohler CG, Jewett BA, et al.Burlingame, CA), a lectin associated with blood vessels. We costained with a smooth muscle actin antibody (sc130616, 1:200; Santa Cruz Biotechnology, Dallas, TX) and considered blood vessels expressing smooth muscle

(15) TNF-α elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p-dependent down-regulation of cGMP-dependent kinase 1The Journal of biological chemistrySeptember 21, 2018Choi S, Park M, Kim J, Park W, Kim S, Lee DK, Hwang JY, Choe J, Won MH, Ryoo S, et al.

(16) Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexiaExperimental gerontologyJune 1, 2018Graber TG, Rawls BL, Tian B, Durham WJ, Brightwell CR, Brasier AR, Rasmussen BB, Fry CS.Slides were incubated overnight in primary antibodies against CD31 (#550274, BD Biosciences), αSMA (#sc-130616, Santa Cruz Biotechnology) and laminin at 4°C. The following day, slides were incubated in secondary

(17) Data on the involvement of Meox1 in balloon-injury-induced neointima formation of ratsData in briefFebruary 1, 2018Wu B, Zhang L, Zhu YH, Zhang YE, Zheng F, Yang JY, Guo LY, Li XY, Wang L, Tang JM, et al.Santa Cruz Biotechnology), goat anti-Meox1 (1:200, ab105349, ABCAM), mouse anti-smooth muscle α-actin (α-SMA, 1:100, sc-130616, Santa Cruz Biotechnology), or proliferating cell nuclear antigen (PCNA) (1:200, ab29, Abcam) overnight

(18) Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodelingInternational journal of cardiologyJanuary 15, 2018Wu B, Zhang L, Zhu YH, Zhang YE, Zheng F, Yang JY, Guo LY, Li XY, Wang L, Tang JM, et al.

(19) VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve StimulationCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Lv YX, Zhong S, Tang H, Luo B, Chen SJ, Chen L, Zheng F, Zhang L, Wang L, Li XY, et al.temperature for 2 h for secondary antibodies. The primary antibodies used were: mouse antirat ɑ-SMA (sc-130616; 1:100, Santa Cruz), rabbit anti-rat VAChT (No.139 103; 1:250; Synaptic Systems); rabbit anti-rat CD31

(20) MitoK_ATP channels promote the proliferation of hypoxic human pulmonary artery smooth muscle cells via the ROS/HIF/miR-210/ISCU signaling pathwayExperimental and therapeutic medicineDecember 1, 2017Hu H, Ding Y, Wang Y, Geng S, Liu J, He J, Lu Y, Li X, Yuan M, Zhu S, et al.Smooth muscle cells were confirmed by immunohistochemistry using anti‑α‑actin monoclonal antibody (dilution 1:300; sc‑130616; Santa Cruz Biotechnology, Inc., Dallas, TX, USA) incubated at 37˚C for 2 h. The cells were cultured

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α-Actin (a-SM1) Antibody

α-Actin (a-SM1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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α-Actin (a-SM1) Antibody from Santa Cruz Biotechnology, Inc.

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