MEP50 (D56B8) Rabbit mAb 2018S from Cell Signaling Technology

Product Specs
ItemMEP50 (D56B8) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number2018S
Quantity100 µl
ApplicationsW, IP, eCLIP
ReactivityH, M, R, Mk
TargetMEP50
HostRabbit
NCBI Gene AliasesHKMT1069, MEP-50, MEP50, Nbla10071, p44, p44/Mep50
ClonalityMonoclonal
NCBI Full Gene NameWD repeat domain 77
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneD56B8
Molecular Weight42

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for MTAP -Deleted KRAS -Mutant Pancreatic CancerCancer ResearchSeptember 15, 2025Kristina Drizyte-Miller, Lars D. Engstrom, Jeffrey A. Klomp, Clint A. Stalnecker, Addison G. Stamey, Khalilah E. Taylor, Mallory K. Roach, Ryan Robb, Laura M. Waters, Andrew Calinisan, et al.(CST, #62765, RRID:AB_3697175), PRMT5 (D5P2T) (CST, #79998, RRID:AB_2799945), MEP50 (D56B8) (CST, #2018S, RRID:AB_2215723), Aurora B/AIM1 (AURKB) (E3R8N) (CST, #28711, RRID:AB_3697177), phospho-4E-BP1 (S65)

(2) The PRMT5-splicing axis is a critical oncogenic vulnerability that regulates detained intron splicingiScienceJuly 18, 2025Colin E. Fowler, Natalie A. O’Hearn, Griffin J. Salus, Arundeep Singh, Paul L. Boutz, Jacqueline A. LeesF3165, 1:2000), PRMT5 (Cell Signaling Technology, 2252S, 1:1000), MEP50 (Cell Signaling Technology, 2018S, 1:1000), PRMT9 (Sigma-Aldrich, HPA042537, 1:1000), SmB/B’ (Santa Cruz Biotechnology, sc-374009, 1:1000),

(3) The PRMT5/WDR77 complex restricts hepatitis E virus replicationPLoS pathogensJune 1, 2023Ju X, Yu Y, Ren W, Dong L, Meng X, Deng H, Nan Y, Ding Q.hour at room temperature. Cells were incubated with primary antibody (anti-ORF2 (2G8) or anti-WDR77 (2018S, CST) for 1.5 hours at room temperature. After washed with PBS for three times, cells were incubated

(4) TRAF6 Promotes PRMT5 Activity in a Ubiquitination-Dependent MannerCancersApril 27, 2023Liu L, Yin S, Gan W.buffer with 5% non-fat milk for Western blotting. Anti-PRMT5 (79998), anti-TRAF6 (8028S), anti-MEP50 (2018S), rabbit anti-Myc-tag (2278), and rabbit anti-HA (3724) were purchased from Cell Signaling Technology

(5) Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced NeurotoxicityFrontiers in Cellular NeuroscienceNovember 19, 2018Thomas M. Piers, Emma East, Claudio Villegas-Llerena, Ioanna G. Sevastou, Mar Matarin, John Hardy, Jennifer M. Pocock

(6) Regulation of FGF10 Signaling in Development and DiseaseFrontiers in GeneticsOctober 23, 2018Joanne Watson, Chiara Francavilla

(7) Small Force, Big Impact: Next Generation Organ-on-a-Chip Systems Incorporating Biomechanical CuesFrontiers in PhysiologyOctober 9, 2018Ece Ergir, Barbara Bachmann, Heinz Redl, Giancarlo Forte, Peter Ertl

(8) Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER StressCell reportsOctober 9, 2018González-García I, Contreras C, Estévez-Salguero Á, Ruíz-Pino F, Colsh B, Pensado I, Liñares-Pose L, Rial-Pensado E, Martínez de Morentin PB, Fernø J, et al.

(9) Epithelial Cells Expressing EhADH, An Entamoeba histolytica Adhesin, Exhibit Increased Tight Junction ProteinsFrontiers in Cellular and Infection MicrobiologySeptember 28, 2018Abigail Betanzos, Dxinegueela Zanatta, Cecilia Bañuelos, Elizabeth Hernández-Nava, Patricia Cuellar, Esther Orozco

(10) The Role of Abnormal Placentation in Congenital Heart Disease; Cause, Correlate, or Consequence?Frontiers in PhysiologyAugust 7, 2018Jennifer A. Courtney, James F. Cnota, Helen N. Jones

(11) Making glycoproteins a little bit sweeter with PDB-REDOActa Crystallographica. Section F, Structural Biology CommunicationsJuly 26, 2018Bart van Beusekom, Thomas Lütteke, Robbie P. Joosten

(12) Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic NeurodegenerationFrontiers in Aging NeuroscienceJune 5, 2018Aijuan Yan, Yu Zhang, Jingya Lin, Lu Song, Xijin Wang, Zhenguo Liu

(13) Alzheimer's disease drug development pipeline: 2018Alzheimer's & Dementia : Translational Research & Clinical InterventionsMay 3, 2018Jeffrey Cummings, Garam Lee, Aaron Ritter, Kate Zhong

(14) Array profiling reveals contribution of Cthrc1 to growth of the denervated rat urinary bladderAmerican journal of physiology. Renal physiologyMay 1, 2018Zhu B, Ekman M, Svensson D, Lindvall JM, Nilsson BO, Uvelius B, Swärd K.no. 12953; Cell Signaling), osteopontin (SPP1, ab91665; Abcam), CD68 (MCA5709; Bio-Rad), WDR77 (D56B8, no. 2018S; Cell Signaling), FLOT2 (no. 3436S; Cell Signaling), ␤-actin (A5441; Sigma Aldrich), and HSP90 (610418;

(15) Identification of a T cell gene expression clock obtained by exploiting a MZ twin designScientific ReportsJuly 20, 2017Daniel Remondini, Nathan Intrator, Claudia Sala, Michela Pierini, Paolo Garagnani, Isabella Zironi, Claudio Franceschi, Stefano Salvioli, Gastone Castellani

(16) Phosphoglycerate Mutase 1 Predicts the Poor Prognosis of Oral Squamous Cell Carcinoma and is Associated with Cell MigrationJournal of CancerJuly 5, 2017Dadong Zhang, Heming Wu, Xiaomin Zhang, Xu Ding, Min Huang, Meiyu Geng, Hongwei Li, Zuoquan Xie

(17) S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cellsNucleic acids researchNovember 16, 2016Warner MJ, Bridge KS, Hewitson JP, Hodgkinson MR, Heyam A, Massa BC, Haslam JC, Chatzifrangkeskou M, Evans GJ, Plevin MJ, et al.

(18) Severe systemic toxicity and urinary bladder cytotoxicity and regenerative hyperplasia induced by arsenite in arsenic (+3 oxidation state) methyltransferase knockout mice. A preliminary reportToxicology and Applied PharmacologyJuly 1, 2010Masanao Yokohira, Lora L. Arnold, Karen L. Pennington, Shugo Suzuki, Satoko Kakiuchi-Kiyota, Karen Herbin-Davis, David J. Thomas, Samuel M. Cohenand on a 12 h light/dark schedule (0600/ 1800 CST). Mice were provided with diet (irradiated Teklad 2018S with Fenbendazole, Harlan Teklad, Madison WI) and hyperchlorinated (b10 ppm chlorine) reverse osmosis

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MEP50 (D56B8) Rabbit mAb

MEP50 (D56B8) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (18)

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MEP50 (D56B8) Rabbit mAb from Cell Signaling Technology

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