Snail (C15D3) Rabbit mAb 3879S from Cell Signaling Technology

Product Specs
ItemSnail (C15D3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3879S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetSnail
HostRabbit
NCBI Gene AliasesSLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
ClonalityMonoclonal
NCBI Full Gene Namesnail family transcriptional repressor 1
Research AreaDevelopmental Biology
CloneC15D3
Molecular Weight29

Questions and Answers

Can this Snail antibody be used to study epithelial-mesenchymal transition in cancer models?

Yes, the Snail (C15D3) Rabbit mAb has been utilized in various studies to investigate its role in epithelial-mesenchymal transition (EMT), which is a critical process in cancer progression. For instance, it has been referenced in studies examining the regulation of EMT markers in breast cancer cells, highlighting its relevance in understanding tumor biology and metastasis.

What species can this antibody detect, and is it effective for human samples?

The Snail antibody is reactive with multiple species, including humans, mice, rats, and non-human primates. It has been shown to effectively detect endogenous levels of total Snail protein in human samples, making it suitable for studies involving human tissues.

How has this antibody been applied in recent research regarding cancer?

The Snail antibody has been cited in several recent studies, including those exploring its role in regulating cancer-associated fibroblasts and their influence on tumor invasion and metastasis. For example, it was used in immunohistochemistry to assess Snail expression in tumor samples, contributing to insights into tumor-stroma interactions.

What is the recommended dilution for using this antibody in Western blot applications?

The Snail (C15D3) Rabbit mAb is typically used at a dilution of 1:1000 for Western blot applications, as indicated in various studies that have successfully employed this antibody to analyze Snail protein levels in different cancer models.

Cell Signaling Technology

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Phone: 978-867-2388
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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal CancerJ Cell Mol MedApril 29, 2026Hien Thi My Ong, Eda Ates, Jaeyong Jung, Jeong Soo Sung, Jae-Chul Pyun, Min-Jung Kangwas used as the loading control. Antibodies against FAK (#3285), phospho‐FAK (Tyr397, #3284), snail (#3879), glutaminase 1 (GLS1, #56750), glutamate–ammonia ligase (GLUL, #80636), glutamate dehydrogenase (GLUD,

(2) Elucidating the Potential Targets and Mechanisms of Bisphenol A-Induced Prostate Cancer Based on Network Toxicology and Molecular Docking AnalysesOncol ResApril 22, 2026Ashuai Du, Dianbin Guo, Dongbo Yuan, Kai Li, Yuanyuan Luo, Songsong Tan, Xuchao Dai, Bo Yu, Wanxiang You, Junjie Zhao, et al.N-cadherin (CST #13116, 1:1000), β-catenin (CST #8480, 1:1000), vimentin (CST #5471, 1:1000), Snail (CST #3879, 1:1000), Slug (CST #9585, 1:1000), and Twist1 (CST #90445, 1:1000). All primary antibodies were purchased

(3) PRDX1 promotes clear cell renal cell carcinoma progression by modulating EGFR-dependent AKT pathway activationFront PharmacolApril 17, 2026Zhi Liang, Xiaochun Lin, Shen Zeng, Lili Wu, Yujun Dong, Chen Zhang, Mei Li, Fudi Zhu, Lu Chen, Suiqin NiAKT (4691T,CST), p-AKT (Ser473, 4060L, CST), PI3K (4257T, CST), p-PI3KP85(Tyr458, 4228S, CST), Snail (3879S, CST), E-cad (3195S, CST), N-cad (13116S, CST), KI67 (ab15580, Abcam) and β-Actin (sc-47778, Santa Cruz)

(4) CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progressioniScienceApril 17, 2026Jiebang Jiang, Xinxin Zhang, Yipeng Sun, Jing Chen, Bo Yuan, Xincheng Li, Xi Chen, Xin Chen, Rongpeng LiAB_3740750 Slug (C19G7) Rabbit mAb,CST,Cat #9585; RRID:AB_2239535 Snail (C15D3) Rabbit mAb,CST,Cat #3879; RRID:AB_2255011 GAPDH Monoclonal antibody,Proteintech,Cat # 60004-1-Ig; RRID: AB_3740751 ,, Biological

(5) FGFR1 Promotes Malignant Progression in Lung Squamous Cell Carcinoma Through Activation of Wnt/β-Catenin SignalingCancer MedApril 17, 2026Xingyuan Li, Shuya Mu, Yinjia Sun, Yongfeng Yu(67491‐1‐Ig; Proteintech), E‐Cadherin (3195; CST), N‐Cadherin (13116; CST), Vimentin (5741; CST), Snail (3879; CST), GAPDH (5174; CST), and β‐actin (4970; CST). 2.4 RNA Extraction, cDNA Synthesis, and qPCR RNA

(6) Proliferation And Apoptosis Adaptor Protein 15 (PEA15), a potential oncogenic regulator of VHL and HIF1A identified through proteomic analysis in hepatocellular carcinomaCancer CommunicationsApril 8, 2026Yun Seong Jeong, Yun Seong Jeong, Ji-Hyun Shin, Soo Mi Sohn, Sun Young Sohn, Sun Young Yim, Ji-Hoon Shim, Sung Hwan Shim, Sung Hwan Chun, Sunyoung S. Chun, et al.11922, Cell Signaling Technology), anti-Snail family transcriptional repressor 1 (SNAI1) (1:1,000, #3879, Cell Signaling Technology), anti-signal transducer and activator of transcription 3 (STAT3) (1:1,000,

(7) Endogenous promoter G-quadruplexes scaffold apurinic/apyrimidinic endonuclease (APE1) to drive gene expressionNucleic Acids ResApril 2, 2026Yingling Chen, Bhopal Mohapatra, Suravi Pramanik, Mason Tarpley, Achyuth Kalluchi, Sutapa Ray, Kyle Hewitt, M Jordan Rowley, Vimla Band, Kishor K BhakatPrimary antibodies used included: APE1 (Novus, Cat# NB100-101), Snail (Cell Signaling Technology, Cat# 3879), c-Jun (Cell Signaling Technology, Cat# 9165), and HSC70 (Santa Cruz Biotechnology, Cat# sc-7298).

(8) Disrupting the TGF-β-regulated epithelial-mesenchymal transition, apoptotic and autophagic phenotypes of 3D glioblastoma spheroids via glycolytic inhibitionExploration of Targeted Anti-tumor TherapyMarch 30, 2026Maellis Payet-Desruisseaux, Alain Zgheib, Bogdan Alexandru Danalache, Michel Desjarlais, Borhane Annabiagainst TGF-β (56E4, 3709 S), AKT (11521, 9272 S), phospho-AKT Ser473 (12604, 4060 S), Snail (C15D3, 3879 S), Smad2 (D43B4, 5339 S), Smad3 (C67H9, 9523 S), phospho-Smad2 Ser465/467 (138D4, 3108 S), and phospho-Smad3

(9) Rapamycin Prevents Sulfate-Reducing Bacteria-Induced Effects on Snail and GSK-3 and Impaired Intestinal BarrierMicroorganismsMarch 30, 2026Sudha B. Singh, Cody A. Braun, Amanda Carroll-Portillo, Henry C. Linin antibodies against actin (Cell Signaling Technology: 4970) and Snail (Cell Signaling Technology: #3879), phosphorylated GSK-3a/b Ser 21/9 (9331) and total GSK-3b (12456). Antibodies were diluted as recommended

(10) Abrine targets ERK to suppress EMT and lung metastasis model via MAPKs and Nrf2/Keap-1/HO-1 signalingFrontiers in ImmunologyMarch 27, 2026Yufang Shen, Linyu Xiao, Lina Liu, Lianting Liao, Xianmin Zou, Pengfei Shen, Jinlong Zhao, Renyikun Yuan, Hongwei Gao, Chun YaoN-cadherin (#113116S, CST, 1:1000), Vimentin (#5741S, CST, 1:1000), Slug (#9585S, CST, 1:1000), Snail (#3879S, CST, 1:1000), Nrf2 (#AF0639, Affinity, 1:1000), Keap-1 (#J1022, SANTA, 1:1000), HO-1 (#HA721854, HUABIO,

(11) piR-37524 Overexpression in Colorectal Cancer: A Potential Diagnostic Bio-Marker and Therapeutic TargetOncology ResearchMarch 23, 2026Jiaxi Li, Deepak Iyer, Siming Sui, Zheng Huang, Ryan Wai-Yan Sin, Abraham Tak-Ka Man, Wai-Lun Law, Chi-Chung Foo, Lui Ng(1:1000, Cell Signaling Technology, Cat. No. 8480), Snail (1:1000, Cell Signaling Technology, Cat. No. 3879), TNFAIP3 (1:1000, ABclonal, Cat. No. A1741, Woburn, USA), and GAPDH (1:5000, Santa Cruz Biotechnology,

(12) Hungatella hathewayi: A Tumor-Derived Bacterium Enriched in Colorectal Cancer Tissues and a Potential Diagnostic BiomarkerMicroorganismsMarch 21, 2026Wenzhe Zhang, Jin Liu, Shanshan Sha, Qiulong Yan, Yufang MaPTM-6222, PTM BioLab Inc., Hangzhou, China), Vimentin (Cat. PTM-5376, PTM BioLab Inc.), Snail1 (Cat. 3879, Cell Signaling Technology, Inc., Danvers, MA, USA), and β-actin (Cat. PTM-5455, PTM BioLab Inc.), followed

(13) Synaptic plasticity in the perforant pathway drives inhibitory reorganization enhancing dentate gyrus functionalityiScienceMarch 20, 2026Cristian Estarellas, Efrén Álvarez-Salvado, Laura Pérez-Cervera, José María Caramés, Elena Pérez-Montoyo, Víctor J. López-Madrona, Raquel Garcia-Hernandez, Claudio R. Mirasso, Santiago CanalsRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Rabbit monoclonal anti-Snail,Cell Signaling Technology,Cat#3879S; RRID:AB_2255011 Mouse monoclonal anti-Tubulin (clone DM1A),Sigma-Aldrich,Cat#T9026; RRID:AB_477593 ,, Bacterial

(14) Single-cell mitophagy signature-based artificial intelligence model enhances prediction of prognosis and immunotherapy response in non-small-cell lung cancerRespiratory ResearchMarch 18, 2026Ming-Hao Wang, Yu Wang, Yi-Tong Li, Dilinaer Wusiman, Mei Lu, Cheng-Yi Zhang, Ye-Xiong Li, Nan Bi(#MA5-24981, 1:2000, Invitrogen), E-cadherin (#14472, 1:1000, CST), Vimentin (#5741, 1:1000, CST), Snail (#3879, 1:1000, CST), P-ERK1/2 (#4370, 1:1000, CST), ERK1/2 (#4695, 1:1000, CST) and GAPDH (#5174 T, 1:10000,CST)

(15) Chemokine-Like Receptor 1 Knockdown Suppresses Oral Squamous Cell Carcinoma Progression by Reducing Oxidative PhosphorylationInt Dent JMarch 17, 2026Yanzhu Lin, Luodan Zhao, Ying Huang, Yuee Chen, Quan Wan, Zhiyuan Lu, Xiangsong ZhangCell Signaling Technology, Danvers, MA, USA), vimentin (#5741; Cell Signaling Technology), Snail (#3879; Cell Signaling Technology), Slug (#9585; Cell Signaling Technology), PI3K (#AF6241; Affinity Biosciences,

(16) Alkaloids from Evodia rutaecarpa inhibit the occurrence and development of gallbladder cancer in vivo and in vitroScientific ReportsMarch 13, 2026Yijie Li, Shufen Zhou, Hanzheng Xu, Hongye Zhou, Kunqi Sun, Siyang Hu, Ke Xu, Jiahua Yang, Yafeng Chen, Wei LiT, rabbit IgG), MMP2 (CST, 87809 S, rabbit IgG), vimentin (Abcam, ab92547, rabbit IgG), Snail (CST, 3879 S, rabbit IgG), ZEB1 (Abcam, ab3829, rabbit IgG), p-PI3K (CST, 4228 S, rabbit IgG), PI3K (CST, 4257

(17) Natural panax notoginseng-derived nanovesicles trigger multiple cell death mechanisms and reprogram chemokine signaling to impede oral squamous cell carcinoma progressionJournal of NanobiotechnologyMarch 6, 2026Xiaohang Chen, Meifang Lin, Xuzheng Zhan, Genggeng Zheng, Shuoqi Lin, Liyu Huang, Chaochao Zhang, Yuxiang Yan, Hengyi Li, Zhaoyu Zhang, et al.phospho-MAPK (#4370), p38 (#9212), phospho-p38 MAPK (#4511), JNK (#9252), phospho-JNK (#4668), SNAIL (#3879), SLUG (#9585), CHD1 (#4351), CHD2 (#4170), Cleaved-GSDME (55879 T) , GPX4 (59735), (Cell Signaling Technology

(18) LncRNA VCAN-AS1 Sponges miR-374c-3p to Promote Proliferation, Invasion, Migration, and EMT in Thyroid CancerInt J EndocrinolMarch 6, 2026Yan Zhang, Lu Sun, Yuqi Wu, Yingzhao Liu, Hui Jiang, Xiaoluo Chen, Li Wang, Chenguang Wuanti‐vimentin (1:1000, 60330‐1‐LG, proteintech), anti‐slug (1:1000, ab51772, Abcam), anti‐snail (1:1000, 3879T, Cell Signaling Technology), and anti‐GAPDH (1:10000, 60004‐1‐Ig, proteintech). Then, the ECL Western

(19) Involvement of c-Myc/WWP1/TRIM65 Axis in Renal FibrosisBiomoleculesMarch 2, 2026Sonia Mazumder, Cody Gifford, Jiaqi Tang, Fortis Gaba, Varsha Mondal, Roel Goldschmeding, Rohan Samarakoon, Paul J. Higginsanti-SMAD5 (1:1000; 12534), rabbit anti-phospho-SMAD1/5 (1:1000; 9516), rabbit anti-snail (1:1000; 3879), rabbit anti-phospho Histone H3 (1:1000; 9701) from Cell Signaling Technology (Danvers, MA, USA), mouse

(20) The protease inhibitor gabexate mesylate targets Raf kinase inhibitor protein and reverses epithelial-mesenchymal transition in triple-negative breast cancer cellsFront OncolMarch 2, 2026Marzia Deserti, Simone Sabbioni, Francesca Poli, Francesco Vasuri, Valeria Relli, Andrea Palloni, Chiara Deiana, Giovanni Brandi, Simona TavolariD21H3 (#5741), rabbit anti-N-Cadherin (#13116), rabbit anti-Claudin-1 (#13255), rabbit anti-Snail (#3879), rabbit anti-Slug (#9585), rabbit anti-E-Cadherin (#3195), rabbit anti β-Catenin clone D10A8 (#8480),

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3/31/2022Time Course Effect of Chemoattractant on SNAIL Expression Somasundaram RaghavanZinc finger protein SNAI1 is a protein that in humans is encoded by the SNAI1 gene. Here we checked the time course effect of SNAIL by chemoattractant.
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4/27/2018Good Western Blot Antibody Rebecca WatesWe have identified a class of ATPase inhibitors that show promise for treatment of ovarian cancer. We are currently evaluating what mechanisms, if any, may lead to resistance to theses ATPase ... Read Review

Snail (C15D3) Rabbit mAb

Snail (C15D3) Rabbit mAb from Cell Signaling Technology

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Snail (C15D3) Rabbit mAb from Cell Signaling Technology

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