Caveolin-1 (D46G3) XP ® Rabbit mAb 3267S from Cell Signaling Technology

Product Specs
ItemCaveolin-1 (D46G3) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number3267S
Quantity100 µl
ApplicationsW, IP, IHC-P, IF-F, IF-IC, FC-FP
ReactivityH, M, R, Hm, Mk, B, Dg
Targetcaveolin-1
HostRabbit
NCBI Gene AliasesBSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
ClonalityMonoclonal
NCBI Full Gene Namecaveolin 1
Research AreaProtein Folding and Trafficking
IsotypeIgG
CloneD46G3
Molecular Weight21, 24

Questions and Answers

What types of applications can I use this Caveolin-1 antibody for in my experiments?

The Caveolin-1 (D46G3) XP® Rabbit mAb has been shown to work effectively in various applications including Western Blotting, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry on paraffin-embedded sections, and Immunoprecipitation.

Is this antibody suitable for use in studies involving endothelial cells?

Yes, the Caveolin-1 antibody has been utilized in studies involving endothelial cells, as evidenced by its application in immunohistochemistry to analyze brain vascular pathology in models of COVID-19, where it was used to assess the expression of Caveolin-1 in endothelial cells.

Can this antibody be used in animal models, and if so, which species have been studied?

The Caveolin-1 antibody is reactive with several species, including human, mouse, rat, canine, bovine, hamster, and non-human primates, making it suitable for use in various animal models.

Are there any specific findings in the literature that highlight the role of Caveolin-1 in cellular processes?

Yes, studies have indicated that Caveolin-1 plays a significant role in cellular processes such as autophagy and inflammation. For instance, one study demonstrated that the expression of Caveolin-1 is involved in the modulation of macrophage responses during sepsis, highlighting its importance in immune regulation.

Cell Signaling Technology

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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Analysis of the expression of FAP, Caveolin1, and CPXM2 and prognostic significance in gastric cancerFront OncolApril 13, 2026Lijie Zhou, Huihu He, Tie Zhao, Wang Du, Guoping Lu, Lingjun Gengantibodies for multiplex immunohistochemistry (mIHC) staining over a period of one hour: CAV1 antibody (3267s, 1:1000, Cell Signaling Technology, Danvers, MA, USA), FAP antibody (ab207178, 1:500, Abcam, Cambridge,

(2) Mucin-binding protein shuttles enable delivery of brain-targeted therapeuticsbioRxivApril 12, 2026Sophia M. Shi, Gabrielle S. Tender, Jian Xiong, Josephine K. Buff, Hannah I. Park, Justin H. Mendiola, Edward N. Wilson, Monther Abu-Remaileh, Carolyn R. Bertozzi, Tony Wyss-Corayfor 1.5 h: goat anti-CD31 (1:100, R&D, AF3628), rabbit anti-CAV1 (1:100, Cell Signaling Technologies, 3267S), mouse anti-CLTC (1:100, Thermo, MA1-065), rabbit anti-mCherry (1:100, Cell Signaling Technologies,

(3) De novo design of Ras isoform selective bindersCell Chem BiolMarch 19, 2026Jason Z. Zhang, Xinting Li, Alexa Rane Batingana, Caixuan Liu, Hanlun Jiang, Kevin Shannon, Benjamin J. Huang, Kejia Wu, David BakerRas,CST,Cat#91054 Rb anti-GFP,CST,Cat#2555 Rb anti-Hsp90,CST,Cat#4877 Rb anti-Caveolin-1,CST,Cat#3267 "Streptavidin, Alexa Fluor™ 488 conjugate",ThermoFisher,Cat#S11223 anti-C-Myc Antibody (Chicken) -

(4) Activated protein C drives β-arrestin-2- and c-Src-dependent phosphorylation of Cav1 and modulates Cav1 association with PAR1 and GRK5Journal of Biological ChemistryMarch 1, 2026Huaping Qin, Lennis B. Orduña-Castillo, Olivia Molinar-Inglis, Monica L. Gonzalez Ramirez, Miguel A. Lopez-Ramirez, Carolyne Bardeleben, JoAnn Trejothe following antibodies were used: mouse anti–PAR1 WEDE (Beckman Coulter, #IM2584), anti-Cav1 (CST, #3267S and BD, #610060), anti-Cav1 Y14 phospho antibody (CST, #3251), anti-βarr2 (Abcam, #ab54790), GAPDH (GeneTex,

(5) Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomersNeurobiology of DiseaseMarch 1, 2026Brianna Hnath, Srinivasan Ekambaram, Nikolay V. Dokholyan,Cell Signaling,3177 C4F6,Medimabs,MM-0070-2-P C9orf72,Proteintech,"22,637–1-AP" Capping protein (Rb anti CARMIL2),My Bio Source, CAV1,Cell Signaling,3267 T Cavin-1,Cell Signaling,"69,036 T" CD9,VWR,"10,084–398" CDK5,Proteintech,"10,430–1-AP" CHMP2B,Proteintech,"12,527–1-AP" CLASP2,Cell Signaling

(6) ROR1-PI3K/AKT signaling drives adaptive resistance to cell cycle blockade in TP53 mutated ovarian cancerCell Death & DiseaseFebruary 27, 2026Juuli Raivola, Frida Rantanen, Alice Dini, Emilia Piki, Harlan Barker, Elina Multamäki, Franziska Bentz, Pia Sunkel, Aino-Maija Kiiski, Lassi Paavolainen, et al.β-tubulin (#2146, Cell Signaling Technology (CST), Danvers, MA, USA), β-actin (#4967, CST), caveolin 1 (#3267, CST), FoxO3a (#99199, CST), c-MYC (#13987, CST), AKT (#2920, CST), AKT-pSer473 (#4060, CST), E-cadherin

(7) Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermisCell Death DiscoveryFebruary 19, 2026Morna F. Schmidt, Maria A. Feoktistova, Diana Panayotova-Dimitrova, Eva Miriam Buhl, Peter Boor, Tim Ruhl, Jens Waschke, Ritva Tikkanen, Martin Röcken, Jens M. Baron, et al.(L8918) (both Sigma-Aldrich, St. Louis, USA), Dsg3 (sc-23912, Santa Cruz, California, USA); Caveolin-1 (#3267) and NIK (#4994) (both Cell Signaling, Danvers, USA), cFLIP (NF6) and caspase-8 (C-15) were kindly gifted

(8) Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradationJournal of Translational MedicineFebruary 4, 2026Ke-Rong Zhai, Pei-Lin Zhao, Zi-Han Wang, Hai-Ming Feng, Zhen-Qing Li, Hui-Rong Huang, Ning Yang, Zhi-Peng Su, Bai-Qiang Cui, Tie-Niu Song, et al.Multiplex immunofluorescence (IF) staining of the TMA was performed using antibodies against CAV1 (CST, #3267; 1:500), CD163 (Proteintech, #16646-1-AP; 1:1,000), and pan Cytokeratin (HUABIO, #HA601094; 1:500).

(9) Insulin receptor trafficking and interactions in muscle cellsJournal of the Endocrine SocietyJanuary 28, 2026Haoning Howard Cen, Aurora J Mattison, Alireza Omidi, Jason Rogalski, Libin Abraham, Guang Gao, Michael R Gold, Leonard J Foster, Jörg Gsponer, James D JohnsonTriton X-100 (Sigma-Aldrich) for 15 minutes, primary antibodies targeting caveolin-1 (1:400, Rabbit mAb, Cat. #3267, Cell Signaling, RRID: AB_2275453) and CLTC heavy chain (1:200, Goat pAb, Cat. #sc-6579, Santa Cruz,

(10) L-Borneolum Attenuates Ischemic Stroke Through Remodeling BBB Transporter Function via Regulating MFSD2A/Cav-1 Signaling PathwayBrain SciencesJanuary 20, 2026Peiru Wang, Yilun Ma, Dazhong Lu, Li Wen, Fengyu Huang, Jianing Lian, Mengmeng Zhang, Taiwei DongElement-Binding Protein 1 (Anti-SREBP1) antibody (#95879) and Anti-caveolin-1 (Anti-CAV-1) antibody (mAb #3267) were obtained from Cell Signaling Technology (Boston, MA, USA). Anti-MFSD2A antibody (AB_11152332)

(11) Aquaporin‐4 and caveolin‐1 as mediators of fibrinogen‐driven cerebrovascular pathology in cerebral amyloid angiopathyAlzheimer's & DementiaJanuary 18, 2026Vishal Singh, Nicholas Rochakim, Francesca Ferraresso, Khushi Garg, Asma B. Rizvi, Arnab Choudhury, Christian J. Kastrup, Hyung Jin Ahnanti‐collagen IV (1/250) (Millipore, AB769), (4) anti‐caveolin‐1 (1/1000) (Cell Signaling Technology, 3267S), (5) anti‐CD31 (1/30) (BD Pharmingen, 550274), (6) anti‐CD11b (1/200) (Cell Signaling Technology, 17800),

(12) CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activationAnnals of MedicineDecember 31, 2025Li Wang, Yi Song, Yan Shu, Baorui Xue, Fangyang Yu, Yao Yin, Ziyun Feng, Xiang Ma, Yulin Yao, Yangze Pan, et al.follows: anti-CAVIN-2 (ELK Biotechnology, ES13173, AB_3097811), anti-CAV1 (Cell Signaling Technology, 3267, AB_2275453), anti-eNOS (Cell Signaling Technology, 9572, AB_329863), anti-p-eNOS (Cell Signaling Technology,

(13) Elevated intracellular copper induces CTR1 monomerization and prevents copper uptakeNat CommunDecember 12, 2025Meng-Hsuan Wen, Huanhuan Chen, Guangjie Yan, Yuteng Zhang, Wenkai Chen, Martin V. Dokholyan, Jian Wang, Nikolay V. Dokholyan, Tai-Yen Chenanti-β-Actin (Sigma-Aldrich A5441, 1:5000 dilution), anti-Caveolin-1 rabbit IgG (Cell Signaling Technology 3267, 1:1000 dilution) or anti-Na+/K+-ATPase alpha1 IgG (Santa Cruze sc-21712, 1:1000 dilution) as a loading

(14) Linking Megalin, Cubilin, Caveolin-1, GIPC1 and Dab2IP Expression to Ocular Tumorigenesis: Profiles in Retinoblastoma, Choroidal Melanoma, and the Normal Human EyeCancers (Basel)November 26, 2025Petra Kovačević, Petar Todorović, Nela Kelam, Suzana Konjevoda, Nenad Kunac, Josipa Marin Lovrić, Katarina Vukojević,Human/Mouse/Rat Cubilin Antibody,#AF3700,Sheep,1:50,"R&D Systems, Inc., Minneapolis, MN, USA" Primary,Caveolin-1 (D46G3) XP® Rabbit mAb,#3267S,Rabbit,1:300,"Cell Signaling Technology (CST), Danvers, MA, USA" Primary,Gipc1 Polyclonal antibody,14822-1-AP,Rabbit,1:100,"Proteintech Group, Inc

(15) Novel genotypes, phenotypes, and triggers in humans with OTULIN haploinsufficiencyJournal of Human ImmunityNovember 3, 2025Tristan J. van der Linden, Rob J.W. Arts, Catherine M. Biggs, Laleh Habibi, Laura Batlle-Masó, Arjan van Laarhoven, Lisette M. Scheepmaker, Pariya Yousefi, Andrea C. Gómez-Raccio, Zahra Alizadeh, et al.Cat# MABS451; Millipore, RRID:AB_2929000), anti–Caveolin-1 rabbit monoclonal antibody (1:1,000, Cat# 3267; Cell Signaling Technology, RRID:AB_2275453), and anti–β-actin mouse monoclonal antibody (1:1,000, Cat#

(16) BK channels are indispensable for endothelial function in small pulmonary arteriesCell Commun SignalOctober 21, 2025Divya Guntur, Dusan Jeremic, Reka Csaki, Oleh Myronenko, Valentina Biasin, Dagmar Kolb, Laura Michalick, Wolfgang M. Kuebler, Peter Enyedi, Horst Olschewski, et al.UC Davis, CA, USA, anti-PIEZO1: 15939-1-AP, Proteintech, Rosemont, IL, USA, anti-caveolin1: D46G3 #3267, Cell signaling, Danvers, MA, USA, anti- GAPDH: ab9485, Abcam, Cambridge, UK, anti-B-Actin: sc4778,

(17) Senescent fibroblasts modulate the radiation response of neighboring epithelial cellsCell Death DiscovOctober 20, 2025Maja Buchholzki, Lisa Marie Stasch, Bettina Budeus, Vaanilaa Ketheeswaranathan, Zehra Fatma Sevindik, Verena Jendrossek, Diana Kleinproteins were used for SDS-PAGE electrophoresis as previously described [19, 76]. The CAV1 (D46G3; #3267) and p21 Waf1/CIP1 (12D1; #2947) antibodies were from Cell Signaling Technology (Danvers, MA; all 1:1000),

(18) Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarizationPLoS PathogOctober 6, 2025Shivraj M. Yabaji, Suruchi Lata, Anna E. Tseng, Prasanna Babu Araveti, Ming Lo, Igor Gavrish, Aoife K. O'Connell, Hans P. Gertje, Anna C. Belkina, Colleen E. Thurman, et al.RRID:AB_2650514), HIF-1α (Cell Signaling Technology, Cat# 48085), Caveolin-1 (Cell Signaling Technology, Cat# 3267, RRID:AB_2275453), TTF1 (Abcam, Cat# ab76013, RRID:AB_1310784), N-Terminal Pro-Surfactant Protein-C

(19) Synergistic Upregulation of Extracellular Vesicles and Cell-Free Nucleic Acids by Chloroquine and Temozolomide in Glioma Cell CulturesInternational journal of molecular sciencesOctober 4, 2025Aleksandrov AE, Bankov BI, Djeliova VL, Antov GG, Stoichev S, Mironova RS, Iliev DB.Cell Signaling Technology (Danvers, MA, USA): mouse anti-LC3B (83506S) and rabbit anti-caveolin-1 (3267S); from Abcam (Waltham, MA, USA): mouse anti-CD63 (ab59479) and mouse anti-alix (ab117600); from Merck

(20) A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor SuppressionCancer ResearchSeptember 15, 2025Yan Zhao, Tina Andoh, Fatima Charles, Priyanka Reddy, Kristina Paul, Harsh Goar, Ishrat Durdana, Caiden J. Golder, Ashley N. Hardy, Marisa M. Juntilla, et al.α-Rab7 (Cell Signaling Technology, #9367, RRID: AB_1904103), α-caveolin (Cell Signaling Technology, #3267, RRID: AB_2275453), α-EEA1 (Cell Signaling Technology, #3288, RRID: AB_2096811), α-LAMP1 (Cell Signaling Technology

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Caveolin-1 (D46G3) XP ® Rabbit mAb

Caveolin-1 (D46G3) XP ® Rabbit mAb from Cell Signaling Technology

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Caveolin-1 (D46G3) XP ® Rabbit mAb from Cell Signaling Technology

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