Anti-PARP antibody GTX100573 from GeneTex

Product Specs
ItemAnti-PARP antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX100573
Quantity25 µl
FormatPBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300
Antibody TypePrimary Antibodies
ClonalityPolyclonal
Conjugate/TagUnconjugated
ReactivityHuman, Mouse, Rat
HostRabbit
ApplicationsWB, ICC/IF, IHC-P, IP, ChIP assay
ImmunogenRecombinant protein encompassing a sequence within the center region of human PARP1. The exact sequence is proprietary
Concentration0.3mg/ml
NCBI Full Gene Namepoly(ADP-ribose) polymerase 1
NCBI Gene AliasesPPOL, ADPRT, ARTD1, PARP-1, Poly-PARP, ADPRT 1, PARS, PARP, poly(ADP-ribose) polymerase 1, ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1, ADPRT1, pADPRT-1
PurityPurified by antigen-affinity chromatography
TargetPARP
IsotypeIgG
Research AreaCancer, Cell Biology
Gene NamePARP1
Molecular Weight113

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Aberrant mitochondrial hsp60 expression affects mitochondria homeostasis and results in muscle dystrophy and premature deathCell Death & DiseaseJanuary 8, 2026Tsung-Hsien Chen, Chu-Kuang Chou, Kurt Ming-Chao Lin(GTX105661, Genetex), Bax (GTX109683, Genetex), BAK (GTX32463, Genetex), Caspase 8 (GTX31284, Genetex), PARP (GTX100573, Genetex), Beclin 1 (GTX133555, Genetex), ubiquitins (3933, Cell Signaling, MA), LC3B (2775, Cell Signaling),

(2) Quantitative Proteomics Unveils the Synergistic Effects of Combination Drugs on Cytoskeleton Composition and Autophagy-Mediated Cell Death in NeuroblastomaJournal of Proteome ResearchJuly 4, 2025Pei-Chen Yu, Yi-Chun Kao, Hsin-Yi Chang, Chen-Hao Huang, Wen-Ming Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan1:1000, GeneTex), Caspase3 and cleaved Caspase3 (GTX110543, 1:500, GeneTex), PARP and cleaved PARP (GTX100573, 1:5000, GeneTex), and GAPDH (GAP001R, 1:5000, Bioman) as the internal control. The following day, the

(3) BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathwayScience advancesSeptember 6, 2024Prosdocimi E, Carpanese V, Todesca LM, Varanita T, Bachmann M, Festa M, Bonesso D, Perez-Verdaguer M, Carrer A, Velle A, et al.

(4) Berberine Improves Cancer-Derived Myocardial Impairment in Experimental Cachexia Models by Targeting High-Mobility Group Box-1International Journal of Molecular SciencesApril 26, 2024Kei Goto, Rina Fujiwara-Tani, Shota Nukaga, Yoshihiro Miyagawa, Isao Kawahara, Ryoichi Nishida, Ayaka Ikemoto, Rika Sasaki, Ruiko Ogata, Shingo Kishi, et al.USA","Abcam, Waltham, MA, USA" β-actin,ab8227,"Abcam, Waltham, MA, USA","Abcam, Waltham, MA, USA" PARP,GTX100573,"GeneTex, Irvine, CA, USA","GeneTex, Irvine, CA, USA" HMGB1,3E8,"Biolegend, San Diego, CA, USA","Biolegend,

(5) Lovastatin Treatment Inducing Apoptosis in Human Pancreatic Cancer Cells by Inhibiting Cholesterol Rafts in Plasma Membrane and MitochondriaInternational Journal of Molecular SciencesNovember 27, 2023Momoko Gyoten, Yi Luo, Rina Fujiwara-Tani, Shiori Mori, Ruiko Ogata, Shingo Kishi, Hiroki KuniyasuTarget,Clone,Dilution,Code,Manufacturer,Location PARP,-,1:400,GTX100573,GeneTex,"Irvine, CA, USA" Caveoin-1,A-6,1:300,sc-393013,Santa-Cruz,"Santa Cruz, CA, USA" EGFR,CDX2-88,1:500,ab157524,Abcam,"Waltham,

(6) Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axisChinese medicineOctober 27, 2023Zhou B, Wang L, Yang S, Liang Y, Zhang Y, Pan X, Li J.(Thr180/Tyr182) (4631S, Cell Signaling Technology), anti-P38 (8690s, Cell Signaling Technology), anti-PARP (GTX100573, GeneTex), anti-cleaved caspase 3 (Asp175) (9664s, Cell Signaling Technology). Following reacting with

(7) The triglyceride-glucose index predicts 1-year major adverse cardiovascular events in end-stage renal disease patients with coronary artery diseaseCardiovascular diabetologyOctober 27, 2023Xie E, Ye Z, Wu Y, Zhao X, Li Y, Shen N, Gao Y, Zheng J.

(8) YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditionsCell death discoveryOctober 20, 2023Chang HA, Ou Yang RZ, Su JM, Nguyen TMH, Sung JM, Tang MJ, Chiu WT.(Ser473) (CST9271; Cell Signaling Technologies), AKT (CST9272; Cell Signaling Technologies), PARP (GTX100573; GeneTex), Caspase 3 (#ab32042; Abcam), α-tubulin (#ab52866; Abcam), and β-actin (A2066; Sigma-Aldrich),

(9) Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery diseaseTranslational research : the journal of laboratory and clinical medicineOctober 1, 2023Fletcher E, Miserlis D, Sorokolet K, Wilburn D, Bradley C, Papoutsi E, Wilkinson T, Ring A, Ferrer L, Haynatzki G, et al.

(10) Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosisExperimental and therapeutic medicineAugust 1, 2023Wang J, Guan P, Chen Y, Xu M, Wang N, Ji E.

(11) α-Viniferin-Induced Apoptosis through Downregulation of SIRT1 in Non-Small Cell Lung Cancer CellsPharmaceuticals (Basel, Switzerland)May 10, 2023Huang C, Lin ZJ, Chen JC, Zheng HJ, Lai YH, Huang HC.Anti-β-actin antibody (GTX109639), anti-vimentin, anti-SIRT1 (GTX17532), anti-AIF (GTX60476), anti-PARP (GTX100573) and anti-caspase 3 (GTX110543) antibody were purchased from GeneTex (Irvine, CA, USA). 4.2. Cell Culture The

(12) Transcriptional upregulation of MAPK15 by NF-κB signaling boosts the efficacy of combination therapy with cisplatin and TNF-αiScienceDecember 22, 2022Wu DD, Dai LJ, Tan HW, Zhao XY, Wei QY, Zhong QH, Ji YC, Yin XH, Yu FY, Jin DY, et al.NF-κB p65 antibody,Cell Signaling Technology,Cat#8242 Caspase-3 antibody,GeneTex,GTX110543 PARP1 antibody,GeneTex,GTX100573 Xpress antibody,Invitrogen,Cat#46-0528 IκBα antibody,BBI Life Sciences,AB20138a p-H2AX antibody,ABclonal,AP0099 H2AX

(13) Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitorsJournal of enzyme inhibition and medicinal chemistryDecember 1, 2022Lin TE, Sung LC, Chao MW, Li M, Zheng JH, Sung TY, Hsieh JH, Yang CR, Lee HY, Cho EC, et al.

(14) Chronic Hypergravity Induces a Modification of Histone H3 Lysine 27 Trimethylation at TCRβ Locus in Murine ThymocytesInternational journal of molecular sciencesJune 27, 2022Calcagno G, Ouzren N, Kaminski S, Ghislin S, Frippiat JP.

(15) 2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial CellsAntioxidants (Basel, Switzerland)April 8, 2022Charoensaensuk V, Chen YC, Lin YH, Ou KL, Yang LY, Lu DY.IL-1β (Cat. # sc-7884) antibodies from Santa Cruz Biotechnology (Dallas, Texas, USA); PARP (Cat. # GTX100573), IκBα (Cat. # GTX110521), and NF-κB p65 (Cat. # GTX102090) antibodies from GeneTex (Irvine, CA, USA)

(16) GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functionsAutophagyMarch 1, 2022Brun S, Bestion E, Raymond E, Bassissi F, Jilkova ZM, Mezouar S, Rachid M, Novello M, Tracz J, Hamaï A, et al.anti- glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Abnova, H00002597-M01; 1:5,000), rabbit anti-PARP (GeneTex, GTX100573; 1:1,500), rabbit anti-cleaved CASP3 (Asp175; Cell Signaling Technology, 9661; 1:200), goat anti-CTSD

(17) Integrative investigation of the TF-miRNA coregulatory network involved in the inhibition of breast cancer cell proliferation by resveratrolFEBS open bioFebruary 1, 2022Zhou Y, Zhang J, Li W, Zhang D, Wang Z, Zhai Y, Yu H, Li Z.following antibodies were used in western blot detection: PARP (GeneTEX, Irvine, CA, USA; Cat. No. GTX100573), TP53 (Proteintech, Chicago, IL, USA; Cat. No. 10442‐1‐AP), CDK1 (GeneTEX, Irvine, CA, USA; Cat. No.

(18) Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell LinesMolecules (Basel, Switzerland)January 7, 2022Lee CW, Huang CC, Chi MC, Lee KH, Peng KT, Fang ML, Chiang YC, Liu JF.

(19) Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer AggressivenessCancersJanuary 4, 2022Lin CH, Liao CC, Wang SY, Peng CY, Yeh YC, Chen MY, Chou TY.Santa Cruz Biotechnology Inc.), anti-OGT (1:2000; 11576-2-AP; Proteintech, Rosemont, IL, USA), anti-PARP1 (1:1000; GTX100573; GeneTex, Hsinchu City, Taiwan), anti-β-Actin (1:20000; NB600-501; Novus Biologicals, Centennial, CO.

(20) Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via FerroptosisFrontiers in pharmacologyJanuary 1, 2022Qin LY, Guan P, Wang JX, Chen Y, Zhao YS, Yang SC, Guo YJ, Wang N, Ji ES.

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7/27/2018Great PARP Antibody for Western Blot Ju-Fang LiuThis antibody was used to detect PARP expression in MG63 cell line by western blot analysis.

Anti-PARP antibody

Anti-PARP antibody

Anti-PARP antibody

Anti-PARP antibody

Anti-PARP antibody from GeneTex

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Anti-PARP antibody from GeneTex

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