Anti-alpha Smooth Muscle Actin antibody GTX100034 from GeneTex

Product Specs
ItemAnti-alpha Smooth Muscle Actin antibody
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX100034
ClonalityPolyclonal
Antibody TypePrimary Antibodies
Quantity25 µl
ApplicationsWB, ICC/IF, IHC-P, IHC-Fr
HostRabbit
Conjugate/TagUnconjugated
ReactivityHuman, Mouse, Rat, Zebrafish
FormatPBS, 20% Glycerol, 0.025% ProClin 300
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human alpha Smooth Muscle Actin. The exact sequence is proprietary
Concentration1.32mg/ml
IsotypeIgG
Targetalpha Smooth Muscle Actin
NCBI Full Gene Nameactin alpha 2, smooth muscle
NCBI Gene AliasesACTSA, actin alpha 2, smooth muscle, ACTSA
PurityPurified by antigen-affinity chromatography
Research AreaCell Markers
Gene NameACTA2
Molecular Weight42

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regenerationJournal of NanobiotechnologySeptember 2, 2023Boram Son, Minju Kim, Hyosub Won, Ara Jung, Jihyun Kim, Yonghoe Koo, Na Kyeong Lee, Seung-Ho Baek, Uiyoung Han, Chun Gwon Park, et al.PBST solution overnight on a rocker at 4 ℃. To investigate fibrosis, anti-α-SMA antibody (Genetex, GTX100034), anti-TGFβ-1 antibody (Bioss, BS-0086R), and anti-TGFβ-2 antibody (Bioss, BS-20412R) were used. After

(2) Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathwayBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieMay 1, 2023Chiou WC, Huang GJ, Chang TY, Hsia TL, Yu HY, Lo JM, Fu PK, Huang C.

(3) Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK)Antioxidants (Basel)April 28, 2023Fernando E. García-Arroyo, Guillermo Gonzaga-Sánchez, Alejandro Silva-Palacios, Francisco Javier Roldán, María L. Loredo-Mendoza, Yamnia Quetzal Alvarez-Alvarez, Jesus A. de los Santos Coyotl, Kevin A. Vélez Orozco, Edilia Tapia, Horacio Osorio-Alonso, et al.Transforming growth factor beta (Genetex, GTX45121, 1:5000 dilution), alpha-smooth muscle actin (Genetex, GTX100034) 1:3000 dilution), Histone H3 (Genetex, GTX122148, 1:10,000 dilution), and beta-actin (Genetex, GTX109639,

(4) Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung FibroblastsMethods and protocolsJanuary 24, 2023Fuentes-Mateos R, Santos E, Fernández-Medarde A.(Sigma, X100);Alexa Fluor™ 488 phalloidin (Invitrogen, A12379);Alpha-smooth muscle actin (GeneTex, GTX100034);Cy3-AffiniPure Goat Anti-Rabbit IgG (H + L) (Jackson ImmunoResearch, 111-165-003);ProLong Diamond antifade

(5) Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung CancerInternational journal of molecular sciencesJanuary 12, 2023Andreucci E, Bugatti K, Peppicelli S, Ruzzolini J, Lulli M, Calorini L, Battistini L, Zanardi F, Sartori A, Bianchini F.The primary antibodies were mouse anti-alpha smooth muscle actin (human, mouse rat) (1:1000, Genetex GTX100034 Alton Pkwy, Irvine, CA, USA), rabbit anti-E Cadherin (1:1000, Cell signaling Technology, Danvers, MA

(6) Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosisClinical and translational medicineNovember 1, 2022Chi JY, Hsiao YW, Liang HY, Huang TH, Chen FW, Chen CY, Ko CY, Cheng CC, Wang JM.

(7) The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transitionJournal of biomedical scienceJune 28, 2022Chen JH, Wu CH, Jheng JR, Chao CT, Huang JW, Hung KY, Liu SH, Chiang CK.in the animal model and in HK-2 cells were from Abcam (Cambridge, UK); anti-α-smooth muscle actin (GTX100034), anti-Trap1 (GTX102017) and anti-vimentim (GTX100619) were from Genetex Inc. (Irvine, CA, USA); anti-GAPDH

(8) Microsomal prostaglandin E synthase-1 is involved in the metabolic and cardiovascular alterations associated with obesityBritish journal of pharmacologyJune 1, 2022Ballesteros-Martínez C, Rodrigues-Díez R, Beltrán LM, Moreno-Carriles R, Martínez-Martínez E, González-Amor M, Martínez-González J, Rodríguez C, Cachofeiro V, Salaices M, et al.

(9) H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failureBMC cardiovascular disordersApril 19, 2022Yan F, Chen Z, Cui W.GTX132621, GeneTex, Inc., Alton Pkwy Irvine, CA, USA), H3K9me2 (1:1000, GTX54102, GeneTex), α-SMA (1:2000, GTX100034, GeneTex), FN1 (1:1000, ab268020, Abcam), p-TrkB (1:1000, ab229908, Abcam), TrkB (1:1000, GTX54857,

(10) Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritisCell communication and signaling : CCSMarch 9, 2022Chen W, Zhang F, Hou X, Xu H, Tang D.phospho-SMAD3 (Ser423/Ser425) (#GTX00969, antibody specificity determined by Orthogonal validation), ɑ-SMA (#GTX100034), Cyclin D2 (#GTX32545), and Bcl-2 associated X (Bax, #GTX32465, antibody specificity determined by

(11) Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix compositionNature metabolismJanuary 1, 2022Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E, Marques M, Crisan M, Mitro N, Santoro MM.primary antibody for Elastin (1:100, #AB9519-500, Abcam), ERG (1:200, #ab92513, Abcam), and αSMA (1:100, #GTX100034, Genetex) diluted in PBS/GS overnight at 4°C. Negative control sections were only incubated with PBS/GS

(12) Saccharomyces Boulardii Ameliorates Non-alcoholic Steatohepatitis in Mice Induced by a Methionine-Choline-Deficient Diet Through Gut-Liver AxisFrontiers in microbiologyJanuary 1, 2022Yang AM, Lin CY, Liu SH, Syu GD, Sun HJ, Lee KC, Lin HC, Hou MC.liver sections were stained for F4/80 (ab6640, abcam®) and stained for alpha-smooth actin (a-SMA) (GTX100034, GeneTex). Paraffin-embedded intestine sections were stained for ZO-1 (NBP1-85047, Novus). Standard

(13) Characterization of miR-34a-Induced Epithelial-Mesenchymal Transition in Non-Small Lung Cancer Cells Focusing on p53BiomoleculesDecember 9, 2021Kawami M, Takenaka S, Akai M, Yumoto R, Takano M.

(14) Evaluation on epithelial-mesenchymal state and microRNAs focusing on isolated alveolar epithelial cells from bleomycin injured rat lungToxicologySeptember 1, 2021Kawami M, Takenaka S, Kadekaru Y, Akai M, Konaka T, Yumoto R, Takano M.

(15) The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine LeiomyomaNutrientsAugust 31, 2021Chiang YF, Chen HY, Ali M, Shieh TM, Huang YJ, Wang KL, Chang HY, Huang TC, Hong YH, Hsia SM.

(16) Unilateral Ureteral Obstruction for 28 Days in Rats Is Not Associated with Changes in Cardiac Function or Alterations in Mitochondrial FunctionBiologyJuly 16, 2021Prieto-Carrasco R, Silva-Palacios A, Rojas-Morales P, Aparicio-Trejo OE, Medina-Reyes EI, Hernández-Cruz EY, Sánchez-Garibay C, Salinas-Lara C, Pavón N, Roldán FJ, et al.antibodies against alpha-smooth muscle actin (αSMA) were purchased from Abcam (ab49481) and GeneTex (GTX100034, San Antonio, TX, USA). All antibodies were used according to the manufacture’s recommendations. The

(17) Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathwayJournal of ethnopharmacologyJuly 15, 2021Peng M, Yang M, Lu Y, Lin S, Gao H, Xie L, Huang B, Chen D, Shen A, Shen Z, et al.

(18) Zebrafish heart regenerates after chemoptogenetic cardiomyocyte depletionDevelopmental dynamics : an official publication of the American Association of AnatomistsJuly 1, 2021Missinato MA, Zuppo DA, Watkins SC, Bruchez MP, Tsang M.monoclonal anti Pcna (Sigma, P8825) (1:1000); mouse anti MHC (DSHB, F59) (1:50); rabbit anti αSMA (Genetex, GTX100034) (1:200), rabbit anti Mpeg (GeneTex, GTX54246) (1:200). Secondary antibodies were diluted 1:1000 Alexa

(19) Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosisJournal of neuroinflammationJune 12, 2021Milani M, Mammarella E, Rossi S, Miele C, Lattante S, Sabatelli M, Cozzolino M, D'Ambrosi N, Apolloni S.

(20) Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1Journal of cellular and molecular medicineMay 1, 2021Liu J, Ke X, Wang L, Zhang Y, Yang J.

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Anti-alpha Smooth Muscle Actin antibody from GeneTex

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Anti-alpha Smooth Muscle Actin antibody from GeneTex

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