Jak2 (D2E12) XP ® Rabbit mAb 3230L from Cell Signaling Technology

Product Specs
ItemJak2 (D2E12) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $876.00 Inquire
Catalog Number3230L
Quantity300 µl
ApplicationsW, IP, IHC-P
ReactivityH, M, R
TargetJak2
HostRabbit
NCBI Gene AliasesJTK10
ClonalityMonoclonal
NCBI Full Gene NameJanus kinase 2
Research AreaImmunology and Inflammation
IsotypeIgG
CloneD2E12
Molecular Weight125

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Octreotide Counteracts IFN-γ-Induced Endothelial InflammationJ Biochem Mol ToxicolApril 19, 2026Saikat Fakir, Madan Sigdel, Md Matiur Rahman Sarker, Nektarios Barabutis(3313S), Cofilin (3318S), pMLC2 (3674S), MLC2 (8505S), pP38 (9211S), P38 (9212S), pJAK2 (3776S), JAK2 (3230S), pSTAT1 (9167S), STAT1 (9172S), pSTAT3 (9145S), and STAT3 (4904S) antibodies were available from Cell Signaling Technology

(2) An Optimized Conversion of Spermatogonial Stem Cells Into Spinal Cord Neurons Enhances Functional Recovery in Rats After Spinal Cord InjuryCNS Neurosci TherApril 15, 2026Xinyu Guo, Yongjie Zhang, Haihong Zhang, Hao Yangantibody (N3908 Sigma), anti‐Tuj1 antibody (12463), anti‐Map2 antibody (8707), anti‐Jak2 antibody (3230), anti‐phospho‐Jak2 antibody (3771), anti‐Stat3 antibody (9139), and anti‐phospho‐Stat3 antibody (9145)

(3) Sorghum Promotes Cell Proliferation Through Activation of the Growth Hormone/IGF-1-JAK2/STAT5b Signaling Axis In VitroBiology (Basel)April 9, 2026Sanghyeon Park, Dong Young Kang, Hyo Tae Kim, Woo-Shik Shin, Sangwon Lee, Jaehoon Cho, Kyoung-Jin Jangand fetal bovine serum, were purchased from Gibco (Grand Island, NY, USA). Antibodies against JAK2 (#3230), pJAK2 (#3776), pSTAT5 (#9351), and pIGF-1Rβ (#3012s) were obtained from Cell Signaling Technology

(4) Loss of Frmd5 Inhibits Jak2-Stat3 Signalling Pathway and Impairs Cell Apoptosis During Vagina Luminal Formation in Puberty MiceInt J Biol SciMarch 25, 2026Tiantian Su, Zhenbin Wang, Yunjiao Wu, Qianchen Li, Li Tian, Xiaowei Li, Jing Zhang, Miao Yu, Yuqi Xing, Juan Du, et al.anti-Frmd5 (YN3224, 1:100 dilution; Immunoway), anti-DDDDK tag (ab205606, 1:200 dilution; Abcam), anti-Jak2 (3230T, 1:200 dilution; Cell Signalling Technology), anti-Stat3 (ab68153, 1:200 dilution; Abcam), anti-pStat3-Y705

(5) The Mechanism of Action of Stigmasterol in Bone Formation in OsteoporosisCurr Issues Mol BiolMarch 23, 2026Cailian Lu, Hong Li, Zhengbo Liu, Sirui Lü, Junxing LiuSTAT3 (ABclonal, #A1192), Phospho-STAT3 (Tyr705) (ABclonal, #AP0705), JAK2 (Cell Signaling Technology, #3230), and Phospho-JAK2 (Tyr1007/1008) (Cell Signaling Technology, #3776, Danvers, MA, USA). The Cell Counting

(6) Inhibition of IL-6/STAT3 Signaling by N-Trans-Hibiscusamide and Its Derivative in a Mouse Model of Collagen-Induced ArthritisFood Sci NutrMarch 4, 2026Hyung Jin Lim, Seon Gyeong Bak, Jaehoon Bae, Nisansala Chandimali, Eun Jae Park, Seung Woong Lee, Mingyeong Kim, Sang-Hoon Lee, Yeong-Seon Won, Sun Hee Cheong, et al.s,1:1000 ERK1/2,44/42,Primary,CST,#4348 s,1:1000 pJAK2,125,Primary,CST,#3771 s,1:1000 JAK2,125,Primary,CST,#3230 s,1:1000 β‐Actin,42,Primary,CST,#4967 s,1:1000 HRP‐conjugated anti‐rabbit IgG,—,Secondary,CST,#7074

(7) Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitmentSignal Transduct Target TherMarch 3, 2026Ronglu Du, Ting Pan, Yuhan Wang, Yan Fan, Qian Liu, Xixi Tao, Shumin Guo, Danyang Tian, Roger S.-Y. Foo, Keliang Xie, et al.(Cell Signaling Technology, Cat# 3331S), rabbit polyclonal anti-Jak2 (Cell Signaling Technology, Cat# 3230S), rabbit polyclonal anti-pJak2 (Cell Signaling Technology, Cat# 3776S), rabbit polyclonal anti-Akt (Cell Signaling Technology

(8) ALKBH5 promotes ovarian cancer progression by activating Notch2 signalingBiological Procedures OnlineMarch 3, 2026Yanying Liu, Huafeng Luo, Luhong Li, Ziao Gao, Qian Wang, Hao Liu, Ruiyun Wu, Cong PengCell Signaling Technology), anti-Notch2 antibody (#5732, Cell Signaling Technology), anti-JAG2 antibody (#3230, Cell Signaling Technology), anti-CCND1 antibody (#2978, Cell Signaling Technology), anti-c-myc antibody

(9) Complete and partial forms of X-linked MCTS1 deficiency in patients with mycobacterial diseaseJournal of Human ImmunityMarch 2, 2026Qinhua Zhou, Ivan Bagarić, Fabian Komma, Chandhana Prakash, Hassan Abolhassani, Zahra Chavoshzadeh, Lulu Tsao, Taja Vatovec, Camille Soudée, Jérémie Rosain, et al.antibodies (both kindly provided by the Teleman laboratory) and rabbit anti-human JAK2 antibody (Cat# 3230; Cell Signaling Technology) or Beta Actin antibody (C4, HRP:sc-47778) at a dilution of 1:1,000 in 5%

(10) Ellagic acid is associated with reduced pancreatic carcinogenesis and modulation of the IL-6/STAT3 pathwayGenes EnvironMarch 2, 2026Hiroyuki Kato, Aya Naiki-Ito, Masayuki Komura, Yuko Nagayasu, Motonori Sato, Xiaochen Kuang, Aya Nagano, Satoru TakahashiCST), IL-6 (1:1000, I2123, Merck), phospho-JAK2 (Tyr1007/1008) (1:1000, #3771, CST), JAK2 (1:1000, #3230, CST), Cleaved-Caspase 3 (Asp175) (1:1000, #9661, CST), Caspase 3 (1:1000, #9662, CST), β-Actin (1:5000,

(11) Centrosomal JAK2 Tyrosine Kinase Regulates Primary Cilia Length, Cell Proliferation, and Cilia Orientation During Cell MigrationFASEB JFebruary 28, 2026Gaurab Karki, Lilly Boone, Taylor Klaiber, Trevor Lambert, Brooke Kimball, Bethany Burkhart, Mirella Youssef, Maria DiakonovaAntibody,Clone,Supplier,Catalog #,Dilution "Anti‐JAK2 (rabbit, mono)",D2E12 XP,Cell Signaling Technology,3230,1:100 IF 1:1000 IB "Anti‐Arl13B (mouse, mono)",N295B/66,Antibodies Inc. (NeuroMab),75–287,1:100 IF "Anti‐acetylated

(12) ω-3 PUFAs Attenuate Postoperative Ileus by Modulating Macrophage Polarization via the JAK2/STAT3 Signaling PathwayJournal of Inflammation ResearchFebruary 13, 2026Xuan Zhao, Jing Yu, Tianle Zhang, Yufei Zhang, Liuchuang Zhang, Ye Wang, Chen Yi, Huafeng Pan, Haifeng Wang, Miaomiao Ge, et al.(#D2534) were obtained from Sigma-Aldrich (St. Louis, MO, USA). Antibodies against p-JAK2 (#8082), JAK2 (#3230), p-STAT3 (#9145), STAT3 (#4904), p-p65 (#3033), and p65 (#8242) were purchased from Cell Signaling Technology

(13) Angiotensin II Receptor-Associated Protein (AGTRAP) Enhances Glioma Cell Survival Through the IL-6/JAK2/STAT3 Pathway and Correlates With an Immunosuppressive MicroenvironmentCNS Neurosci TherFebruary 13, 2026Siyu Chen, Yuntao Li, Xiaohu Nie, Yonggang Zhang, Qianxue Chen, Xiaoxing Xiong, Zhongzhou Su, Sheng Qiuab2302, 1:1000), anti‐IL‐6 (abcam, ab214429, 1:1000), anti‐p‐JAK2 (CST, 8082, 1:1000), anti‐JAK2 (CST, 3230, 1:1000), anti‐p‐STAT3 (CST, 9145, 1:1000), anti‐STAT3 (CST, 9139, 1:1000), and anti‐β‐actin (abcam,

(14) Mechanism by which Icariin suppresses pulmonary metastasis in triple-negative breast cancer through downregulation of the SPDL1/JAK2/STAT3 signaling pathwayCancer Cell InternationalFebruary 12, 2026Zengyou Xiao, Zean Yang, Xiaotong Li, Xin Chen, Jiaxian Li, Yujie He, Wei Li, Jie Wang(Beyotime, China). The antibodies against Bcl2 (3498), caspase-3 (9662), cleaved caspase-3 (9664), JAK2 (3230), STAT3 (9139), phospho-STAT3 (9145), and GAPDH (2118), as well as the horseradish peroxidase (HRP)-labeled

(15) ELF5 modulates casein synthesis in goat mammary epithelial cells via JAK2/STAT5 signaling pathwayAnimal BioscienceFebruary 1, 2026Yuzhu Guo, Cunxia Ma, Tianxiang Meng, Tongtong Tu, Shuangshuang Cui, Yinghui Ling, Yunhai Zhang, Hongyu Liu, Ning Song(sc-166530; SantaCruz; 1:1,000), p-JAK2 (ab32101; Abcam; 1:1,000), p-STAT5 (9351S; 1:1,000), JAK2 (3230; CST; 1:1,000), STAT5 (610191; BD; 1:1,000), proliferating cell nuclear antigen (PCNA, 10205-2-APl Proteintech,

(16) Interleukin 13 signaling modulates dopaminergic functions and nicotine reward in rodentsMolecular PsychiatryFebruary 1, 2026Xin-an Liu, Carlos A. Aguirre, Qixing Yang, Jiayan Ren, Lina Wang, Furong Ju, Hongling Guo, Jintao Wang, Luping Liu, Zixuan Li, et al.Signalway Antibody, Cat# 48795), STAT3 (CST, Cat# 9139 s), p-STAT3 (CST, Cat# 9134 s), JAK2 (CST, Cat# 3230 s), ERK1/2 (Proteintech, Cat# 11257-1-AP), p-ERK (CST, Cat# 4370 s), GAPDH (Proteintech, Cat# HRP-60004)

(17) Total flavonoids extracted from Penthorum chinense Pursh inhibits oxidative stress and inflammation in liver cancer cells through the JAK2/STAT3 pathwayTranslational Cancer ResearchJanuary 31, 2026Xiaoyan Li, Xiaoqiang Zhang, Junchao Xue(#4967, 45 kDa, 1:1,000, CST, Danvers, MA, USA), phospho- (p-)JAK2 (#4406, 125 kDa, 1:1,000, CST), JAK2 (#3230, 125 kDa, 1:1,000, CST), p-STAT3 (#52075, 86 kDa, 1:1,000, CST), STAT3 (#12640, CST, 79 kDa, 1:1,000,

(18) STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ductsCell ReportsJanuary 27, 2026Rayane Dennaoui, Madison N. Wicker, Carson Moen, Michaela Schlederer, Kerry Vistisen, Aleata A. Triplett, Thomas Rülicke, Hallgeir Rui, Lukas Kenner, Emilio Casanova, et al.(Y1007/1008)",Cell Signaling,Cat#3776; RRID:AB_ 2617123 "Rabbit monoclonal, JAK2",Cell Signaling,Cat#3230; RRID:AB_2128522 "Rabbit polyclonal, pY-STAT1 (Y701)",Origene,Cat#TA309955 "Rabbit monoclonal, pY-STAT1

(19) PLB1 enhances adhesion and invasion of Trichosporon asahii to lung epithelial cells: insights into the mechanisms of Cav1/JAK/STAT3-induced arginine metabolismRespiratory ResearchJanuary 23, 2026He Zhu, Junhong Ao, Xiaoxian Cheng, Xin Yang, Haitao Li, Rongya YangDF13386, Affinity; anti-CCL2: 1:1000, DF7577, Affinity; anti-CCL12: ab9737, Abcam; anti-JAK2: 1:1000, 3230, CST; anti-p-JAK2: 1:1000, 4406, CST; anti-STAT3: 1:1000, 12640, CST; anti-p-STAT3: 1:2000, 9145, CST;

(20) CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistanceCell Reports MedicineJanuary 20, 2026Alex Watterson, Gabriele Picco, Vivien Veninga, Youhani Samarakoon, Chiara M. Cattaneo, Sara F. Vieira, Emre Karakoc, Shriram Bhosle, Thomas W. Battaglia, Sarah Consonni, et al.(#45206, 1:500), STAT1 (#9172, 1:1,000), pSTAT1-Y710 (#7649, 1:1,000), JAK1 (#3344, 1:1,000), JAK2 (#3230, 1:1,000), Cas9 (#14697, 1:1,000), CDX2 (#3977, 1:1,000), vinculin (#13901, 1:1,000), cleaved caspase 3

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(1)

9/29/2022Excellent Anti-JAK2 Antibody Liyong Z.Isolation of murine cardiac extracellular vesicles (EVs) was performed using differential centrifugation. Western blotting confirms that JAK2 protein is activated by IR-EV (0, 108, 109 and 1010 /ml) ... Read Review
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3/2/2016Best JAK2 Antibody A MOur lab works with the kinases involved with kidney cancer, and JAK2 is often a target of our research. We gave this Cell Signaling antibody a chance and have been quite pleased with its ability to ... Read Review

Jak2 (D2E12) XP ® Rabbit mAb

Jak2 (D2E12) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Jak2 (D2E12) XP ® Rabbit mAb from Cell Signaling Technology

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