PARP-1 (E-8) Antibody sc-74469 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPARP-1 (E-8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-74469
Antibody TypePrimary Antibodies
NCBI Gene AliasesmsPARP, Adprp, parp-1, PPOL, ADPRT, ARTD1, PARP-1, ADPRT 1, Poly-PARP, PARS, Adprt1, PARP, 5830444G22Rik, sPARP-1, ADPRT1, pADPRT-1
CloneE-8
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivitymouse, rat, human
Hostmouse
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Namepoly (ADP-ribose) polymerase family, member 1, poly(ADP-ribose) polymerase 1
TargetPARP-1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurationsNucleic acids researchAugust 26, 2022Choi Y, Luo Y, Lee S, Jin H, Yoon HJ, Hahn Y, Bae J, Lee HH.Cell Signaling Technology, Danvers, MA, USA), anti-FLAG (F1804, Sigma-Aldrich), anti-p21 (sc-397, Santa Cruz), anti-PARP1 (sc-74469, Santa Cruz), anti-BAX (sc-493, Santa Cruz) and anti-Caspase 3 (9662, Cell Signaling Technology). Chromatin

(2) Perfluorooctane sulfonate induces autophagy-associated apoptosis through oxidative stress and the activation of extracellular signal-regulated kinases in renal tubular cellsPloS oneJanuary 1, 2021Wen LL, Chen YT, Lee YG, Ko TL, Chou HC, Juan SH.kinases 1 and 2 (pERK1/2; SC-7383, Lot: B1519), poly(adenosine diphosphate-ribose) polymerase (PARP; SC-74469, Lot: E1208), and β-actin ([SC-47778, Lot: G0213], 1:500, Santa Cruz Biotechnology, Santa Cruz, CA,

(3) FOXL2 directs DNA double-strand break repair pathways by differentially interacting with KuNature communicationsApril 24, 2020Jin H, Lee B, Luo Y, Choi Y, Choi EH, Jin H, Kim KB, Seo SB, Kim YH, Lee HH, et al.Santa Cruz Biotechnology; 1:3000), anti-γ-H2AX (#9718S; Cell Signaling Technology, Danvers, MA, USA; 1:1000), anti-PARP-1 (sc-74469; Santa Cruz Biotechnology; 1:1000), anti-α-tubulin (LF-PA0146; AbFrontier, Seoul, Korea; 1:1000), anti-SIRT1

(4) Two novel 1,4‑naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species‑mediated MAPK/Akt/STAT3 signaling pathwaysMolecular medicine reportsSeptember 1, 2019Wang H, Luo YH, Shen GN, Piao XJ, Xu WT, Zhang Y, Wang JR, Feng YC, Li JQ, Zhang Y, et al.

(5) Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometryPloS oneJanuary 1, 2019Hara N, Osago H, Hiyoshi M, Kobayashi-Miura M, Tsuchiya M.expression of PARP1, PARP2, SIRT1, and CD38 with anti-human PARP1 monoclonal (1:1000 dilution, Santa Cruz, sc-74469), anti-human PARP2 polyclonal (1:10000 dilution, Active Motif, 39744), anti-human SIRT1 monoclonal (1:10000,

(6) Artemether suppresses cell proliferation and induces apoptosis in diffuse large B cell lymphoma cellsExperimental and therapeutic medicineNovember 1, 2017Zhao X, Guo X, Yue W, Wang J, Yang J, Chen J.

(7) Genetic variation and RNA structure regulate microRNA biogenesisNature communicationsMay 3, 2017Fernandez N, Cordiner RA, Young RS, Hug N, Macias S, Cáceres JF.(Pierce). Other primary antibodies used in this study were: mouse monoclonal anti-PARP-1 antibody (E-8): sc-74469, Santa Cruz Biotechnology, Dilution 1:500 ); Rabbit polyclonal anti-DDX17 antibody ((S-17): sc-86409,

(8) EGR2 is a gonadotropin-induced survival factor that controls the expression of IER3 in ovarian granulosa cellsBiochemical and biophysical research communicationsJanuary 22, 2017Jin H, Won M, Shin E, Kim HM, Lee K, Bae J.

(9) Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stressPloS oneJanuary 1, 2017Sekulic-Jablanovic M, Petkovic V, Wright MB, Kucharava K, Huerzeler N, Levano S, Brand Y, Leitmeyer K, Glutz A, Bausch A, et al.

(10) PARP-1 depletion in combination with carbon ion exposure significantly reduces MMPs activity and overall increases TIMPs expression in cultured HeLa cellsRadiation oncology (London, England)September 22, 2016Ghorai A, Sarma A, Chowdhury P, Ghosh U.primary antibodies were purchased from Santa Cruz Biotechnology Inc, USA such as mouse anti-PARP1 [sc-74469], mouse anti-MMP-2 [sc-80201], mouse anti-MMP-9 [sc-58389], mouse anti-TIMP-1 [sc-80365], mouse anti-TIMP-2

(11) FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa CellsPloS oneJanuary 1, 2016Jin H, Won M, Park SE, Lee S, Park M, Bae J.Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-GAPDH (sc-25778; Santa Cruz Biotechnology), anti-PARP (sc-74469; Santa Cruz Biotechnology), and control rabbit IgG (sc-2027; Santa Cruz Biotechnology), anti-α-tubulin

(12) Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosisApoptosis : an international journal on programmed cell deathApril 1, 2015Ghorai A, Sarma A, Bhattacharyya NP, Ghosh U.

(13) Regulation of HFE expression by poly(ADP-ribose) polymerase-1 (PARP1) through an inverted repeat DNA sequence in the distal promoterBiochimica et biophysica actaDecember 1, 2013Pelham C, Jimenez T, Rodova M, Rudolph A, Chipps E, Islam MR.

(14) Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2NatureAugust 30, 2012Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S, Fujita R, Guarnieri P, Bhagat G, Vanti WB, Shih A, et al.

(15) Treatment with the PARP-inhibitor PJ34 causes enhanced doxorubicin-mediated cell death in HeLa cellsAnti-cancer drugsJuly 1, 2012Magan N, Isaacs RJ, Stowell KM.

(16) VI-14, a novel flavonoid derivative, inhibits migration and invasion of human breast cancer cellsToxicology and applied pharmacologyJune 1, 2012Li F, Li C, Zhang H, Lu Z, Li Z, You Q, Lu N, Guo Q.

(17) Putative mechanisms of antitumor activity of cyano-substituted heteroaryles in HeLa cellsInvestigational new drugsApril 1, 2012Ester K, Supek F, Majsec K, Marjanović M, Lembo D, Donalisio M, Šmuc T, Jarak I, Karminski-Zamola G, Kralj M.

(18) Novel poly (ADP-ribose) polymerase 1 binding motif in hepatitis B virus core promoter impairs DNA damage repairHepatology (Baltimore, Md.)October 1, 2011Ko HL, Ren EC.

(19) Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic-exposed human population in West Bengal, IndiaEuropean journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)March 1, 2011Roy M, Sinha D, Mukherjee S, Biswas J.

(20) Antagonistic role of tea against sodium arsenite-induced oxidative DNA damage and inhibition of DNA repair in Swiss albino miceJournal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and CancerJanuary 1, 2011Sinha D, Roy M.

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PARP-1 (E-8) Antibody

PARP-1 (E-8) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PARP-1 (E-8) Antibody from Santa Cruz Biotechnology, Inc.

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