c-Myc Antibody AF3696 from R&D Systems, a Bio-Techne Brand

Product Specs
Itemc-Myc Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAF3696
NCBI Gene AliasesbHLHe39, MRTL, MYCC, c-Myc
ApplicationsImmunohistochemistry,Western Blot,Simple Western,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry
Targetc-Myc
HostGoat
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
IsotypeIgG
NCBI Full Gene NameMYC proto-oncogene, bHLH transcription factor
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human c-Myc, Arg66-Asp201, Accession # P01106
ConcentrationLYOPH
PurityAntigen Affinity-purified
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human c-Myc in direct ELISAs. Detects human and mouse c-Myc in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) L-Myc and rhN-Myc is observed.

Sizes Available: 100 ug (also 25 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) c-MYC is an aggregation-prone, amyloidogenic proteinbioRxiv : the preprint server for biologyMay 5, 2026Lin L, Chuang KH, Dai C.anti-cleaved caspase 3 (Asp175) (D3E9) Ab (cat#9579, Cell Signaling Technology), goat polyclonal anti-c-MYC Ab (cat#AF3696, R&D Systems Inc.), mouse monoclonal anti-HA Ab (cat#901513, BioLegend Inc.), mouse monoclonal anti-βActin

(2) Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4Nature CommunicationsSeptember 30, 2025Burak Ozkan, Mitzy Rios de Anda, Elisa Hall-Ponsele, Maria Rosa Portero Migueles, Amani Alshaikh, Marta Hanzevacki, Moriyah Naama, Katharine Furlong, Gareth A. Roberts, Meryam Beniazza, et al.anti-SOX2 0.5 µg/ml (#AF2018; R&D systems), anti-KLF4 0.5 µg/ml (#AF3640, R&D systems), anti-MYC 1 µg/ml (#AF3696; R&D systems), anti-Nanog 0.5 µg/ml (#14-5761-80; eBioscience), or anti-NANOG (ab109250, Abcam). Antibody

(3) AZIN1 level is increased in medulloblastoma and correlates with c-Myc activity and tumor phenotypeJournal of experimental & clinical cancer research : CRFebruary 17, 2025Sesen J, Martinez T, Busatto S, Poluben L, Nassour H, Stone C, Ashok K, Moses MA, Smith ER, Ghalali A.AB223481), GM130 (GeneTex Inc., CA, USA, cat# GTX130351), c-Myc (R&D Systems, Minneapolis, MN, cat# AF3696), c-Myc (Cell Signaling Technology Inc. Danvers, MA, cat# 5605), ODC (R&D Systems, Minneapolis, MN,

(4) STAT1 regulates immune-mediated intestinal stem cell proliferation and epithelial regenerationNature communicationsJanuary 2, 2025Takashima S, Sharma R, Chang W, Calafiore M, Fu YY, Jansen SA, Ito T, Egorova A, Kuttiyara J, Arnhold V, et al.antibodies used were anti-Olfm4 (Cell Signaling Technology, cat# 39141) and anti-c-Myc (R&D Systems, cat# AF3696). Alexa-Fluor-647-conjugated donkey anti-rabbit antibodies and Alexa-Fluor-546-conjugated donkey anti-goat

(5) LncRNA SNHG6 regulating Hedgehog signaling pathway and affecting the biological function of gallbladder carcinoma cells through targeting miR-26b-5pEuropean review for medical and pharmacological sciencesJuly 1, 2020Liu XF, Wang K, Du HC.

(6) Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogrammingCell regeneration (London, England)June 1, 2019Luo Z, Qing X, Benda C, Huang Z, Zhang M, Huang Y, Zhang H, Wang L, Lai Y, Ward C, et al.(MAB2018, R&D Systems), anti-OCT4 (sc-8628, Santa Cruz), anti-KLF4 (AF3158, R&D Systems), anti-MYC (AF3696, R&D Systems), anti-histone H3 (ab1791, Abcam), anti-ACTIN (A5316, Sigma), and anti-GAPDH (G8795, Sigma).

(7) High OGT activity is essential for MYC-driven proliferation of prostate cancer cellsTheranosticsJanuary 1, 2019Itkonen HM, Urbanucci A, Martin SE, Khan A, Mathelier A, Thiede B, Walker S, Mills IG.centrifuged, and the supernatant was used for ChIP. Antibodies for ChIP were: RL2 #ab2739 (Abcam), MYC AF3696 (R&D systems) and HCF-1 #A301-399a (Bethyl Laboratories). ChIP was performed overnight at +4˚C, and

(8) Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-MycBiological & pharmaceutical bulletinJanuary 1, 2019Nagasaka M, Tsuzuki K, Ozeki Y, Tokugawa M, Ohoka N, Inoue Y, Hayashi H.

(9) PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathwayCancer cell internationalJanuary 1, 2019Luo J, Yao Y, Ji S, Sun Q, Xu Y, Liu K, Diao Q, Qiang Y, Shen Y.(Abcam, ab28472, 1:100), anti-CyclinD1 (Cell Signaling Technology, 2978, 1:100), anti-C-Myc (R&D Systems, AF3696, 1:100). Cell lines and cell culture LUAD cell lines (NCIH1975, NCIH1650, PC9, A549, NCIH1299) and

(10) Cooperative Binding of Transcription Factors Orchestrates ReprogrammingCellJanuary 26, 2017Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K.beads. The antibodies used were: anti-Esrrb (RnD; H6705), anti-Klf4 (RnD; AF3158), anti-cMyc (RnD; AF3696), anti- Nanog (cosmobio REC-RCAB001P), anti-Oct4 (RnD; AF1759), anti-Sox2 (RnD AF2018), antip300 (SantaCruz;sc-585),

(11) Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specificationThe EMBO journalFebruary 1, 2016Morrison G, Scognamiglio R, Trumpp A, Smith A.(Santa Cruz, sc8635), 2 μg Miz1 antibody (Santa Cruz H‐190, sc‐22837), 5 μg cMyc antibody (R&D Systems, AF3696) or control antibodies normal goat IgG (R&D Systems, AB‐108‐C) and normal rabbit IgG (R&D Systems, AB‐105‐C).

(12) Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expressionOncotargetJanuary 19, 2016Li GQ, Guo WZ, Zhang Y, Seng JJ, Zhang HP, Ma XX, Zhang G, Li J, Yan B, Tang HW, et al.used for IHC were from the following companies: BRD4 (HPA015055) from Sigma (Shanghai, China); c-MYC (AF3696) from R&D systems (Shanghai, China); and Ki 67 (550609) from BD Biosciences (Shanghai, China). IHC was performed

(13) The regulatory role of c-MYC on HDAC2 and PcG expression in human multipotent stem cellsJournal of cellular and molecular medicineJuly 1, 2011Bhandari DR, Seo KW, Jung JW, Kim HS, Yang SR, Kang KS.electrophoresed on a 10–12% SDS-PAGE. The proteins were detected with primary antibodies for c-MYC (AF3696; R&D Systems, Inc., Minneapolis, MN, USA), HDAC1 (2E10; Millipore, Billerica, MA, USA), HDAC2 (3F3;

(14) PVT1 dependence in cancer with MYC copy-number increaseNatureJanuary 1, 0001"Tseng YY, Moriarity BS, Gong W, Akiyama R, Tiwari A, Kawakami H, Ronning P, Reuland B, Guenther K, Beadnell TC, et al."IMAGE:5517530, Open Bio-systems) according to a standard procedure34, followed by goat anti-MYC antibody (AF3696, 10 μg ml−1, R&D Systems) reaction at 4 °C overnight. The samples were treated with Alexa Fluor 594

(15) Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem CellsStem cells internationalJanuary 1, 0001"Liang Y, Liu X, Zhou R, Song D, Jiang YZ, Xue W."

(16) SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activityNature communicationsJanuary 1, 0001"Wang F, Gao Y, Xue S, Zhao L, Jiang H, Zhang T, Li Y, Zhao C, Wu F, Siqin T, et al."

(17) S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodelingScience advancesJanuary 1, 0001"Greco CM, Cervantes M, Fustin JM, Ito K, Ceglia N, Samad M, Shi J, Koronowski KB, Forne I, Ranjit S, et al."Active Motif, ChIP), anti-H3K9/14ac (#C15410200, Diagenode, ChIP), anti-H3K27me3 (#07-449, Millipore), c-Myc (#AF3696, R&D Systems, ChIP), and normal rabbit immunoglobulin G (IgG) (#10500C, Invitrogen). GST constructs,

(18) Regulation of MicroRNA Machinery and Development by Interspecies S-NitrosylationCellJanuary 1, 0001"Seth P, Hsieh PN, Jamal S, Wang L, Gygi SP, Jain MK, Coller J, Stamler JS."RRID:AB_262044 Rabbit anti-His-tag,Cell Signaling Technology,Cat#2365S RRID:AB_2115720 Myc-antibody,R&D systems,Cat#AF3696 RRID:AB_2282405 Rabbit anti-AGO2,Cell Signaling Technology,Cat#2897 RRID:AB_2096291 ALG-1 antibody,Invitrogen,Cat#PA1-031

Be the First to Write a Review!

Human/Mouse c-Myc Antibody

c-Myc Antibody

c-Myc Antibody

c-Myc Antibody

c-Myc Antibody

c-Myc Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (18)

Reviews

c-Myc Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map