PP2A-B55-α (2G9) Antibody sc-81606 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPP2A-B55-α (2G9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-81606
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Clone2G9
ApplicationsWB, IP, IF
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
ClonalityMonoclonal
Hostmouse
FormatPurified
NCBI Gene AliasesB55ALPHA, B55A, 2410004D02Rik, PR55alpha, PR55A, mKIAA1541, PR52A
NCBI Full Gene Nameprotein phosphatase 2, regulatory subunit B, alpha, protein phosphatase 2 regulatory subunit Balpha
TargetPP2A-B55alpha
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Protein phosphatase 2A subunit B55 alpha is required for angiotensin type 2 receptor elicited natriuresisAmerican Journal of Physiology-Renal PhysiologyJanuary 1, 2026John J. Gildea, Jie Li, Nancy L. Howell, Brandon A. Kemp, Mark R. Conaway, David L. Brautigan, Robert M. Carey, Susanna R. Keller(Santa Cruz H-143; cat. no. sc-9040; 1:100) and simultaneously with PP2A B55α (Santa Cruz; cat. no. sc-81606; 1:100), PP2A A (Santa Cruz; cat. no. sc-13600; 1:100), or PP2A B56γ (Santa Cruz A-11; cat. no. sc-374379;

(2) Germline loss-of-function mutations in PPP2R1B in patients with a personal and family history of cancerJCI InsightMay 8, 2025Sahar Mazhar, Caitlin M. O’Connor, Alexis Harold, Amanda C. Dowdican, Peter J. Ulintz, Erika N. Hanson, Yuping Zhang, Michelle F. Jacobs, Sofia D. Merajver, Mark W. Jackson, et al.(Cell Signaling Technology, 13202S), PP2Ac (Abcam, ab106262), PP2A regulatory subunit Bα (B55α) (Santa Cruz Biotechnology, sc-81606), PP2A regulatory subunit Bβ (B56β) (Santa Cruz Biotechnology, sc-515676), PP2A regulatory subunit Bγ

(3) Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55αnpj Metabolic Health and DiseaseNovember 6, 2024Nicola M. Sergienko, Adam J. Trewin, Helen Kiriazis, Antonia J. A. Raaijmakers, Daniel G. Donner, Victoria C. Garside, Kelly A. Smith, James R. Bell, Kimberley M. Mellor, Lea M. D. Delbridge, et al.were expressed as fold difference relative to the control group. Antibodies were as follows: B55α (#sc-81606, Santa Cruz, 1:1000), FoxO1 (#2880, Cell Signaling Technology, 1:2000), pSer256 FoxO1 (#9461, Cell Signaling Technology

(4) Biochemical characterization of the Eya and PP2A-B55α interactionThe Journal of biological chemistryJuly 1, 2024Alderman C, Anderson R, Zhang L, Hughes CJ, Li X, Ebmeier C, Wagley ME, Ahn NG, Ford HL, Zhao R.added to the 66cl4 cell lysate and rotated on a vertical rotator at 4 °C ON with α-B55α (Santa Cruz, sc-81606). The Protein A/G beads were washed 3× with 1 ml of the lysis buffer. Next, the co-IP product was eluted

(5) Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell DeathMolecular cancer therapeuticsMay 4, 2023Avelar RA, Armstrong AJ, Carvette G, Gupta R, Puleo N, Colina JA, Joseph P, Sobeck AM, O'Connor CM, Raines B, et al.Bethyl Laboratory: p-RPA (A300–245A); (iii) Santa Cruz Biotechnology: Vinculin (sc-73614), GAPDH (sc-47724), B55α (sc-81606; iv) EMD Millipore BRCA2 (OP95), and (v) a gift from Dr. Egon Ogris's Laboratory B56α-3A6D3. Cell-cycle

(6) Excess folic acid supplementation before and during pregnancy and lactation activates β-catenin in the brain of male mouse offspringBrain research bulletinJanuary 1, 2022Wu Q, Zhou D, Wu R, Shi R, Shen X, Jin N, Gu J, Gu JH, Liu F, Chu D.

(7) FBXL16 Promotes Endometrial Progesterone Resistance via PP2A(B55α) /Cyclin D1 Axis in IshikawaJournal of immunology researchJanuary 1, 2022Liu H, Han L, Zhong L, Zhuang X, Peng Y.in NP-40 lysis buffer. Antibodies to PP2A/C subunits (Santa Cruz, sc-80665), PP2AB55-α (Santa Cruz, sc-81606), PP2A/A subunits (Santa Cruz, sc-56954), and FBXL16 (Thermo Fisher, PA5-58818) were incubated with

(8) Wip1 controls the translocation of the chromosomal passenger complex to the central spindle for faithful mitotic exitCellular and molecular life sciences : CMLSMarch 1, 2021Zhang X, Park JE, Kim EH, Hong J, Hwang KT, Kim YA, Jang CY.

(9) CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication StressMolecular cellNovember 5, 2020Li F, Kozono D, Deraska P, Branigan T, Dunn C, Zheng XF, Parmar K, Nguyen H, DeCaprio J, Shapiro GI, et al.9111S;RRID:AB_331460 PP2A-B55-alpha,Sigma,Cat# SAB4300573;RRID:AB_10622182 PP2A-B55-alpha,Santa Cruz Biotechnology,Cat# SC-81606;RRID:AB_2252935 HA-Tag,Cell Signaling Technology,Cat# 3724S;RRID:AB_1549585 Flag,Sigma,Cat# F3165;RRID:AB_259529 Flag,Sigma,Cat#

(10) The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence contextScience signalingJanuary 28, 2020Schüchner S, Behm C, Mudrak I, Ogris E.

(11) Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat HeartsAnesthesia and analgesiaJanuary 1, 2020Lou PH, Lucchinetti E, Hersberger M, Clanachan AS, Zaugg M.

(12) The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosisEBioMedicineNovember 1, 2019Chen P, Wang B, Mo Q, Wu P, Fang Y, Tian Y, Jin X, Gao Y, Wu Y, Cao Y, et al.

(13) A Cancer-Associated Missense Mutation in PP2A-Aα Increases Centrosome Clustering during MitosisiScienceSeptember 27, 2019Antao NV, Marcet-Ortega M, Cifani P, Kentsis A, Foley EA.

(14) Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancerCell death and differentiationMay 1, 2018Álvarez-Fernández M, Sanz-Flores M, Sanz-Castillo B, Salazar-Roa M, Partida D, Zapatero-Solana E, Ali HR, Manchado E, Lowe S, VanArsdale T, et al.

(15) Eya3 partners with PP2A to induce c-Myc stabilization and tumor progressionNature communicationsMarch 13, 2018Zhang L, Zhou H, Li X, Vartuli RL, Rowse M, Xing Y, Rudra P, Ghosh D, Zhao R, Ford HL.dilution), anti-PP2A-C IgG (Cell signaling, 2038, 1:3000 dilution), anti-PP2A-B55α IgG (Santa Cruz, sc-81606, 1:500 dilution), anti-B56α IgG (Santa Cruz, sc-6116, 1:500 dilution), anti-PP2A-Aα IgG (Santa Cruz,

(16) β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573Journal of molecular and cellular cardiologyFebruary 1, 2018Ranieri A, Kemp E, Burgoyne JR, Avkiran M.and Bethyl (A301-100A), respectively. PP2AA and B55α antibodies were from Santa Cruz (sc-74580 and sc-81606, respectively). GFP and α-Actinin antibodies were from Roche (11814460001) and Sigma (A7732), respectively.

(17) β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated DephosphorylationJournal of the American Heart AssociationMarch 25, 2017Weeks KL, Ranieri A, Karaś A, Bernardo BC, Ashcroft AS, Molenaar C, McMullen JR, Avkiran M.

(18) Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloidPloS oneJanuary 1, 2017Asam K, Staniszewski A, Zhang H, Melideo SL, Mazzeo A, Voronkov M, Huber KL, Pérez E, Stock M, Stock JB, et al./Cell Signaling 1:1000 CREB Sc-186/Santa Cruz 1:100 CREB-P (Ser133) Sc-7978/Santa Cruz 1:200 PP2A subunit B55-α Sc-81606/Santa Cruz 1:200 phospho-tau S396/404 PHF-1Peter Davies 1:500 phospho-tau S202 CP13/Peter Davies 1:500 Total

(19) miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growthNature communicationsNovember 10, 2015Mihailovich M, Bremang M, Spadotto V, Musiani D, Vitale E, Varano G, Zambelli F, Mancuso FM, Cairns DA, Pavesi G, et al.system (Amersham or Bio-Rad). Primary antibodies against MYC (sc-N-262), Ppp2r2a (PP2A B55-alpha 2G9; sc-81606), E2F1 (KH95; sc-251), GMF-β (C-17; sc-46999), Cdkn1b (sc-528) and N-RAS (C-20 sc-519) were purchased

(20) Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancerBMC cancerApril 15, 2015Beca F, Pereira M, Cameselle-Teijeiro JF, Martins D, Schmitt F.pretreatment and antigen retrieval, the slides were incubated with the primary antibodies for PPP2R (sc-81606; Santa Cruz Biotechnology, diluted 1:50) and Cyclin D1 (SP4; Neomarkers, diluted 1:50). For the discovery

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PP2A-B55-α (2G9) Antibody

PP2A-B55-α (2G9) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PP2A-B55-α (2G9) Antibody from Santa Cruz Biotechnology, Inc.

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