Fig 1: Effects of chronic restraint stress and XYS on the tumour microenvironment. (a) CD11b+F4/80+ cells were quantified by flow cytometry in disaggregated HT-29 primary spleen tumour harvested 28 days after cell injection. (b) Data represent the average CD11b+F4/80+ composition. (c) CD11b+GrloLy6Chi and CD11b+GrhiLy6Clo cells were quantified by flow cytometry in disaggregated HT-29 primary spleen tumour harvested 28 days after cell injection. (d) Data represent the average CD11b+GrloLy6Chi composition. *p< 0.05, **p< 0.01 and ***p< 0.001. BC: blank-control; BS: blank-stress; XC: XYS-control; XS: XYS-stress.