IL-7R alpha/CD127 Antibody (R34-34)

Product Specs
ItemIL-7R alpha/CD127 Antibody (R34-34) - Azide and BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberDDX0700P-100
Quantity0.1 mg
ApplicationsFlow Cytometry,Immunoprecipitation,Block/Neutralize
Concentration0.5 mg/ml
Conjugate/TagUnconjugated
ReactivityCanine,Human
TargetIL-7R alpha/CD127
IsotypeIgG1
CloneR34-34
HostMouse
ImmunogenIL7R Alpha/CD127 was used as immunogen
NCBI Full Gene Nameinterleukin 7 receptor
NCBI Gene AliasesILRA, sIL-7R, CD127, IL-7R-alpha, IL7RA, IL-7Ralpha, CDW127, lnc-IL7R, IMD104, IL7Ralpha
ClonalityMonoclonal
PurityIon exchange chromatography
Research AreaApoptosis, Cytokine Research, Immunology, Innate Immunity
FormatTris-NaCl (pH 8.0)
Antibody TypePrimary Antibodies
StorageStore at -20C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

Questions and Answers

Can this IL-7R alpha/CD127 antibody be used for flow cytometry applications?

Yes, the IL-7R alpha/CD127 antibody (R34-34) has been shown to work in flow cytometry applications, allowing for the analysis of IL-7 receptor expression on various cell types.

What species can I use this antibody with in my experiments?

This antibody is reactive with both human and canine species, making it suitable for studies involving these organisms.

Is there any literature supporting the use of this antibody in immunoprecipitation?

Yes, the IL-7R alpha/CD127 antibody has been cited in scientific literature for use in immunoprecipitation, indicating its effectiveness in isolating the IL-7 receptor from complex biological samples.

What is the immunogen used for this antibody, and how does it relate to its specificity?

The immunogen for this antibody is IL7R Alpha/CD127, which is directly related to its specificity for the IL-7 receptor. This specificity is crucial for accurate detection and analysis in various immunological studies.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Generation of multipotent early lymphoid progenitors from human embryonic stem cellsStem cells and developmentDecember 15, 2014Larbi A, Mitjavila-Garcia MT, Flamant S, Valogne Y, Clay D, Usunier B, l'Homme B, Féraud O, Casal I, Gobbo E, et al.

(2) An immunological biomarker to predict MTX response in early RAAnnals of the rheumatic diseasesNovember 1, 2014Ponchel F, Goëb V, Parmar R, El-Sherbiny Y, Boissinot M, El Jawhari J, Burska A, Vital EM, Harrison S, Conaghan PG, et al.

(3) Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host diseaseBloodJuly 31, 2014Munneke JM, Björklund AT, Mjösberg JM, Garming-Legert K, Bernink JH, Blom B, Huisman C, van Oers MH, Spits H, Malmberg KJ, et al.

(4) GATA binding protein 3⁺ group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonatesThe Journal of allergy and clinical immunologyJuly 1, 2014Forsberg A, Bengtsson M, Eringfält A, Ernerudh J, Mjösberg J, Jenmalm MC.

(5) TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriersMucosal immunologyMay 1, 2014Yu X, Pappu R, Ramirez-Carrozzi V, Ota N, Caplazi P, Zhang J, Yan D, Xu M, Lee WP, Grogan JL.

(6) High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancerCancer researchApril 15, 2014Péguillet I, Milder M, Louis D, Vincent-Salomon A, Dorval T, Piperno-Neumann S, Scholl SM, Lantz O.

(7) Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentationThe Journal of biological chemistryJanuary 3, 2014Compeer EB, Flinsenberg TW, Boon L, Hoekstra ME, Boes M.

(8) IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat proteinPloS oneJanuary 1, 2014Faller EM, McVey MJ, MacPherson PA.

(9) Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-GuérinEuropean journal of immunologyJanuary 1, 2014Lozza L, Farinacci M, Faé K, Bechtle M, Stäber M, Dorhoi A, Bauer M, Ganoza C, Weber S, Kaufmann SH.

(10) Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administrationPLoS pathogensJanuary 1, 2014Sereti I, Estes JD, Thompson WL, Morcock DR, Fischl MA, Croughs T, Beq S, Lafaye de Micheaux S, Yao MD, Ober A, et al.

(11) Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissuesNature immunologyMarch 1, 2013Bernink JH, Peters CP, Munneke M, te Velde AA, Meijer SL, Weijer K, Hreggvidsdottir HS, Heinsbroek SE, Legrand N, Buskens CJ, et al.

(12) IL-7 downregulates IL-7Rα expression in human CD8 T cells by two independent mechanismsImmunology and cell biologyFebruary 1, 2013Ghazawi FM, Faller EM, Sugden SM, Kakal JA, MacPherson PA.

(13) Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivoJournal of immunology (Baltimore, Md. : 1950)January 1, 2013Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T.

(14) NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic functionMolecular cellNovember 9, 2012Yatim A, Benne C, Sobhian B, Laurent-Chabalier S, Deas O, Judde JG, Lelievre JD, Levy Y, Benkirane M.

(15) CD4 T follicular helper cell dynamics during SIV infectionThe Journal of clinical investigationSeptember 1, 2012Petrovas C, Yamamoto T, Gerner MY, Boswell KL, Wloka K, Smith EC, Ambrozak DR, Sandler NG, Timmer KJ, Sun X, et al.

(16) Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 moThe American journal of clinical nutritionFebruary 1, 2012Noakes PS, Vlachava M, Kremmyda LS, Diaper ND, Miles EA, Erlewyn-Lajeunesse M, Williams AP, Godfrey KM, Calder PC.

(17) HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expressionRetrovirologySeptember 16, 2011Young CD, Angel JB.

(18) Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161Nature immunologySeptember 11, 2011Mjösberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, Fokkens WJ, Cupedo T, Spits H.

(19) Low-dose rabbit antithymocyte globulin induction therapy results in prolonged selective lymphocyte depletion irrespective of maintenance immunosuppressionTransplantation proceedingsMarch 1, 2011Pankewycz O, Leca N, Kohli R, Wallace PK, Said M, Feng L, Alnimri M, Patel S, Laftavi MR.

(20) Numbers of CD25+Foxp3+ T cells that lack the IL-7 receptor are increased intra-articularly and have impaired suppressive function in RA patientsRheumatology (Oxford, England)November 1, 2010van Roon JA, Hartgring SA, van der Wurff-Jacobs KM, Bijlsma JW, Lafeber FP.

Be the First to Write a Review!