Brn-3c (QQ8) Antibody sc-81980 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemBrn-3c (QQ8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $333.00Supplier Page View Company Product Page
Catalog Numbersc-81980
Antibody TypePrimary Antibodies
NCBI Gene AliasesDFNA42, Brn3c, DFNA52, BRN3C, dreidel, Brn3.1, DFNA15, ddl
CloneQQ8
Quantity100 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, ELISA
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene NamePOU class 4 homeobox 3, POU domain, class 4, transcription factor 3
TargetBrn-3c
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Hypoxia-Stabilized HIF1α Restricts Hair Cell Reprogramming by Suppressing Wnt Signaling in the Mammalian CochleaCellsAugust 11, 2026Qing Liu, Yuanning Guo, Xinyu Wang, Shu Wang, Ao Li, Guoqiang Wanand 1% heat-inactivated NHS. Hair cells were immunostained with hair cell markers, including Pou4f3 (sc-81980, Santa cruz) and Myo7a (25-6790, Proteus Biosciences, Ramona, CA, USA). For immunofluorescence of the

(2) Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retinaCurrent biology : CBAugust 3, 2026Chaudhari K, Guzman-Clavel LE, Donthi N, Yang J, Harris SC, Lin TH, Dunn FA, Kolodkin AL.RRID:AB_2943521 Guinea Pig anti-Rbpms,Thermo Fisher,Cat#PA5-119676; RRID:AB_2913249 Mouse anti-Brn3c,Santa Cruz,Cat#sc-81980; RRID:AB_2167543 Rabbit anti-Foxp1,Proteintech,Cat#22051-1-AP; RRID:AB_2878980 Rabbit anti-IBA1,Wako

(3) Progression of Vestibular Deficits Following Moderate-Intensity Blast Overpressure in RatsJournal of the Association for Research in OtolaryngologyMarch 11, 2026Jena’ N. Mazique, Caroline Sit, Raven Riley, Zelma Iriarte Oporto, Ian Mcneill, Tianwen Chen, James Warren, David Huang, Youguo Xu, Austin Frisbie, et al.against βII-spectrin (BD Biosciences, cat#: 612562, 1:200) or POU4F3 (Santa Cruz Biotechnology, cat#: sc-81980, 1:200), as markers for hair cells. The next day, samples were treated with secondary antibodies, either

(4) Cisplatin Differentially Damages Mammalian Vestibular End OrgansEar & HearingDecember 31, 2025John Lee, Hong Zhu, Wu Zhou, Lisa L. Cunninghamantibodies and incubated overnight at 4 °C: mouse isotype IgG1 anti-Pou4f3 (Santa Cruz Biotechnology, cat # sc-81980, clone QQ8, 1:200) and rabbit anti-Sox2 (Cell Signaling Technology, cat # 23064, 1:200). Tissues were

(5) Cisplatin Differentially Damages Mammalian Vestibular End OrgansEar HearDecember 31, 2025John Lee, Hong Zhu, Wu Zhou, Lisa L. Cunninghamantibodies and incubated overnight at 4 °C: mouse isotype IgG1 anti-Pou4f3 (Santa Cruz Biotechnology, cat # sc-81980, clone QQ8, 1:200) and rabbit anti-Sox2 (Cell Signaling Technology, cat # 23064, 1:200). Tissues were

(6) Cell-specific α and β subunit expression patterns of Na+/K+-ATPases in the common marmoset cochleaSci RepJuly 23, 2025Makoto Hosoya, Masafumi Ueno, Marie N. Shimanuki, Takanori Nishiyama, Naoki Oishi, Hiroyuki Ozawavascularis),33,Mouse,IgG2a,"60,348–1","Proteintech, Rosemont, IL, USA",1:500 Anti-POU4F3,POU class 4 homeobox 3(Hair cell marker),22,Mouse,IgG1,sc-81980,"Santa Cruz Biotechnology, Santa Cruz, CA, USA",1:200 Anti-NEFH,Neurofilament heavy polypeptide(Neuronal

(7) Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cellsbioRxivFebruary 28, 2025Robert N. Rainey, Sam D. Houman, Louise Menendez, Ryan Chang, Litao Tao, Helena Bugacov, Andrew P. McMahon, Radha Kalluri, John S. Oghalai, Andrew K. Groves, et al.25–6791) Anti-MyosinVIIa (Proteus Bioscience, catalog# 25–6790) Anti-Pou4f3 (Santa Cruz Biotechnology, catalog# sc-81980) Anti-HA tag (Abcam, catalog# ab9110) Anti-Nanog (Abcam, catalog# ab173368) Anti-Pou5f1/Oct4 (Invitrogen,

(8) Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in the mature mouse utricleNature communicationsOctober 24, 2024Wang T, Yang T, Kedaigle A, Pregernig G, McCarthy R, Holmes B, Wu X, Becker L, Pan N, So K, et al.following markers were used: Myosin7a (1:1000; Cat #256790, Proteus Bioscience), Pou4f3 (1:200, Cat # sc-81980, Santa Cruz Biotechnology Inc.), Sall2 (1:200; Cat # HPA004162, Sigma Aldrich), Sox2 (1:250; Cat #AF2018,

(9) A primate model animal revealed the inter-species differences and similarities in the subtype specifications of the spiral ganglion neuronsScientific reportsOctober 24, 2024Hosoya M, Ueno M, Shimanuki MN, Nishiyama T, Oishi N, Ozawa H.Rosemont, IL, USA, 1:500) Anti-AML1 (rb IgG, #4336 (D33G6), Cell Signaling, 1:200), Anti-POU4F3 (ms IgG1, sc81980, Santa Cruz Biotechnology, Santa Cruz, CA, USA, 1:200), Anti-TLE4 (ms IgG1, sc365406, Santa Cruz Biotechnology,

(10) Stub1 promotes degradation of the activated Diaph3: A negative feedback regulatory mechanism of the actin nucleatorThe Journal of biological chemistryOctober 1, 2024Qiu C, Zhang L, Yong C, Hu R, Sun Y, Wang B, Fang L, Zhu GJ, Lu Q, Wang J, et al.used in this study, as follows: rabbit anti-EGFP (1:400, 31002ES60, Yeasen), mouse anti-Pou4f3 (1:200, sc-81980, Santa Cruz), mouse anti-Parvalbumin (1:500, sab4200545, Sigma-Aldrich), rabbit anti-Diaph3 (1:400,

(11) AAV‐mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell RegenerationAdvanced ScienceAugust 1, 2024Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, et al.antibodies were Atoh1 (1:1000 dilution, Santa Cruz, sc‐136173), Pou4f3 (1:1000 dilution, Santa Cruz, sc‐81980), Gfi1 (1:1000 dilution, Santa Cruz, sc‐373960), Six1 (1:1000 dilution, Sigma, HPA001893), and GAPDH

(12) Recovery kinetics of dual AAV-mediated human otoferlin expressionFrontiers in Molecular NeuroscienceJune 17, 2024Jonathan B. Sellon, Kathy S. So, Andrew D'Arcangelo, Sarah Cancelarich, Meghan C. Drummond, Peter G. Slade, Ning Pan, Tyler M. Gibson, Tian Yang, Joseph C. Burns, et al.were used: anti-OTOF (Ms IgG1, Abcam 53,233, 1:200), anti-POU4F3 (1:200, Santa Cruz Biotechnology, sc-81980), Sox2 (1:500; Abcam, ab97959), Secondary antibodies were conjugated with Alexa Fluor 488, 568 and 647

(13) The Suppression of Ubiquitin C-Terminal Hydrolase L1 Promotes the Transdifferentiation of Auditory Supporting Cells into Hair Cells by Regulating the mTOR PathwayCellsApril 24, 2024Yeon Ju Kim, In Hye Jeong, Jung Ho Ha, Young Sun Kim, Siung Sung, Jeong Hun Jang, Yun-Hoon Choungantibodies: anti-SOX2 (1:1000; CST), anti-MYO7A (1:1000; Proteus Biosciences), and anti-BRN3C (1:1000; sc-81980; Santa Cruz Biotechnology, Santa Cruz, CA, USA). The samples were thoroughly washed and incubated at

(14) The transcription factor Pou4f3 is essential for the survival of postnatal and adult mouse cochlear hair cells and normal hearingFrontiers in Cellular NeuroscienceMarch 19, 2024Jarnail Singh, Michelle R. Randle, Bradley J. Walters, Brandon C. CoxVIIa (1:200; cat. #25-6790; Proteus Biosciences, Ramona, CA), mouse IgG1 anti-Pou4f3 (1:300; cat. #sc-81980; Santa Cruz Biotechnology, Dallas, TX), and goat anti-Sox2 (1:400, cat. #sc-17320; Santa Cruz Biotechnology,

(15) Mapping of Notch signaling in the developing organ of Corti in common marmosetsFrontiers in neuroanatomyJanuary 1, 2023Hosoya M, Fujioka M, Okano H, Ozawa H.anti-DLL1 (1:100, mouse IgG2b, MAB18181, R&D, Minneapolis, MN, USA), anti-POU4F3 (1:200, mouse IgG1, sc-81980, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-ATOH1 (1:500, rabbit IgG, 21215-1, Proteintech,

(16) Adult spinal Dmrt3 neurons receive direct somatosensory inputs from ipsi- and contralateral primary afferents and from brainstem motor nucleiThe Journal of comparative neurologyJanuary 1, 2023Vieillard J, Franck MCM, Hartung S, Jakobsson JET, Ceder MM, Welsh RE, Lagerström MC, Kullander K.datasheet). 2.4.6 Anti‐Brn3c The mouse monoclonal IgG1 anti‐Brn3c antibody (Santa Cruz Biotechnology Cat# sc‐81980, RRID:AB_2167543, used at 1:200) was raised against recombinant human Brn3c protein. Western blot performed

(17) Impact of maternal physical exercise on inflammatory and hypothalamic-pituitary-adrenal axis markers in the brain and lungs of prenatally stressed neonatal miceDevelopmental psychobiologyNovember 1, 2022da Costa MS, Luft C, Sbruzzi M, de Oliveira JR, Donadio MVF.

(18) Safety and efficacy of intratympanic histamine injection as an adjuvant to dexamethasone in a noise-induced murine modelEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical SciencesNovember 1, 2022Han JS, Kim YL, Yu HJ, Park JM, Kim YJ, Choung YH, Park SY, Park SN.

(19) Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiationProceedings of the National Academy of Sciences of the United States of AmericaOctober 25, 2022Qin T, Ho CC, Wang B, Hui CC, Sham MH.anti-Atoh1 (Proteintech, 21215-1-AP), rabbit anti-Myo7a (Proteus, 26-6790), mouse anti-Pou4f3 (Santa Cruz, sc-81980), and goat anti-Sox2 (Neuromics, GT15098). Samples were then washed and incubated with Alexa Fluor–labeled secondary antibodies

(20) Early development of the cochlea of the common marmoset, a non-human primate modelNeural developmentMay 7, 2022Hosoya M, Fujioka M, Okahara J, Yoshimatsu S, Okano H, Ozawa H.Antibody,Host,Isotype,Catalog ID,Provider,Dilution Anti-POU4F3,Mouse,IgG1,sc-81980,"Santa Cruz Biotechnology, Santa Cruz, CA, USA",1:200 Anti-ATOH1,Rabbit,IgG,"21,215–1","Proteintech,

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Brn-3c (QQ8) Antibody

Brn-3c (QQ8) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Brn-3c (QQ8) Antibody from Santa Cruz Biotechnology, Inc.

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