ERK 2 (12A4) Antibody sc-81457 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemERK 2 (12A4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Numbersc-81457
Antibody TypePrimary Antibodies
NCBI Gene AliasesErk2, p38, PRKM2, Prkm1, ERK2, ERK-2, MAPK2, p42mapk, p42-MAPK, ERK, 9030612K14Rik, P42MAPK, NS13, p41mapk, ERT1, PRKM1, p41, p40
Quantity50 µg/0.5 ml
Clone12A4
Reactivitymouse, rat, human
ApplicationsWB, IP
FormatPurified
Hostmouse
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Namemitogen-activated protein kinase 1
TargetERK 2
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failureeBioMedicineDecember 1, 2023Ke Qian, Jie Tang, Yue-Juan Ling, Ming Zhou, Xin-Xin Yan, Yu Xie, Lu-Jia Zhu, Koju Nirmala, Kang-Yun Sun, Zheng-Hong Qin, et al.1:1000), AKT (Cell Signaling Technology 4685, 1:1000), P-ERK (Santa Cruz sc7383, 1:500), ERK (Santa Cruz sc81457, 1:500), SIRT3 (Cell Signaling Technology 2627, 1:5000), SIRT1 (Santa Cruz, sc74594, 1:1000), Pan-acetylation

(2) Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosisBiomolecules and BiomedicineOctober 1, 2023Jian Sun, Jiyu Xu, Yong Liu, Yitong Lin, Fengge Wang, Yue Han, Shumin Zhang, Xiaoyan Gao, Changqing Xu, Hui YuanProteintech, Wuhan, China); and ODC, ERK1/2, p-ERK1/2, Pannexin-1, β-actin and β-tubulin (Cat NO. sc-390366, sc-81457, sc-136521, sc-515941, sc-69879, sc-166729 Santa Cruz Biotechnology). And then the membranes were incubated

(3) Chaenomeles Fructus (CF), the Fruit of Chaenomeles sinensis Alleviates IL-1β Induced Cartilage Degradation in Rat Articular ChondrocytesInternational Journal of Molecular SciencesApril 14, 2022Changhwan Yeo, Chae Ryeong Ahn, Jai-Eun Kim, Young Woo Kim, Jinbong Park, Kwang Seok Ahn, In Jin Ha, Yoon Jae Lee, Seung Ho Baek, In-Hyuk Ha,Santa Cruz,1:1000,sc-52658 Aggrecan,Abcam,1:1000,ab36861 NF-κB p65,Cell signaling,1:1000,8242 s p-NF-κB p65,Cell signaling,1:1000,#3033 ERK,Santa cruz,1:1000,sc-81457 p-ERK,Cell signaling,1:2000,#4370 JNK,Cell signaling,1:1000,#9252 P-JNK,Cell signaling,1:2000,#9255 P38,Cell signaling

(4) LncRNA XIST knockdown alleviates LPS-induced acute lung injury by inactivation of XIST/miR-132-3p/MAPK14 pathway : XIST promotes ALI via miR-132-3p/MAPK14 axisMolecular and cellular biochemistryDecember 1, 2021Li C, Liu JH, Su J, Lin WJ, Zhao JQ, Zhang ZH, Wu Q.(sc-7480; 1:1000), anti-MAPK14 (p38α MAPK, sc-81621; 1:1000), anti-ERK1(sc-271269; 1:1000), anti-ERK2 (sc-81457; 1:1000), anti-p-ERK1/2 antibody (Thr 202/Tyr 204) (sc-16982; 1:1000), anti-β-actin (sc-47778; 1:1000)

(5) SHP2 potentiates the oncogenic activity of beta-catenin to promote triple-negative breast cancerMolecular Cancer ResearchNovember 1, 2021Elisha Martin, Yehenew M. Agazieanti–β-catenin (SC-7199), the anti-Myc (SC-40), the anti-cyclin D1 (SC-246), and the anti–pan-ERK2 (SC-81457) antibodies were from Santa Cruz Biotechnology. The remaining antibodies were anti–β-actin (A5441) from

(6) Stress Diminishes BDNF-stimulated TrkB Signaling, TrkB-NMDA Receptor Linkage and Neuronal Activity in the Rat BrainNeuroscienceOctober 1, 2021Siobhan Robinson, Allison S. Mogul, Elisa M. Taylor-Yeremeeva, Amber Khan, Anthony D. Tirabassi, Hoau-Yan Wang(SC8058), -BDNF/pro-BDNF (SC-2098), -NT3 (SC-547), -NT4 (SC-545), -phosphotyrosine (SC-508), -Erk2 (SC-154, SC-81457), -pErk2 (SC-7383), -pAkt1 (SC-7985-R), -Akt1 (SC-65487), -PLC (SC7290), -NR1 (SC-9058), -NR2A (SC-9056),

(7) Ferulic Acid Ameliorates Hepatic Inflammation and Fibrotic Liver Injury by Inhibiting PTP1B Activity and Subsequent Promoting AMPK PhosphorylationFrontiers in pharmacologyJanuary 1, 2021Wu J, Xue X, Fan G, Gu Y, Zhou F, Zheng Q, Liu R, Li Y, Ma B, Li S, et al.from Vazyme Biotech (Nanjing, China). Antibodies against p-ERK1/2 (sc-7383), ERK1 (sc-271269), ERK2 (sc-81457), LKB1 (sc-32245) were purchased from Santa Cruz Biotechnology (Santa Cruz, United States). Antibodies

(8) CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cellsâ€™ Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving PulmonectomyOxidative Medicine and Cellular LongevityApril 9, 2019Jian Wang, Ying Zhou, Li Ma, Shannan Cao, Wei Gao, Qingqing Xiong, Kaiyuan Wang, Lili Yangagainst GAPDH (sc-47724), NHE1 (sc-136239), anti-p-ERK1/2 (sc-101760), and nonphosphorylated ERK1/2 (sc-81457) from Santa Cruz Biotechnology (Santa Cruz, CA, USA); and antibodies against snail (3895S), slug (9585S),

(9) Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesisOncogeneMarch 1, 2019Hua Zhao, Elisha Martin, Fatimah Matalkah, Neal Shah, Alexey Ivanov, J. Michael Ruppert, Paul R. Lockman, Yehenew M. Agaziesite. The other antibodies used were anti-SHP2 (610822) from BD Biosciences, rabbit anti-pan-ERK2 (SC-81457) from Santa Cruz Biotechnology, anti-β-actin (A5441) from Sigma-Aldrich, anti-phospho-ERK1/2 (9101S),

(10) MicroRNA‑144 suppresses aggressive phenotypes of tumor cells by targeting ANO1 in colorectal cancerOncology ReportsFebruary 21, 2019Yasu Jiang, Yunhui Cai, Weiwei Shao, Feng Li, Zongyu Guan, Yi Zhou, Chong Tang, Shichun Fengwere as follows: Anti‑EGFR (cat. no. sc‑71034), anti‑p‑EGFR (cat. no. sc‑81487), anti‑ERK1/2 (cat. no. sc‑81457) and anti‑p‑ERK1/2 (cat. no. sc‑7976) and anti‑ β ‑actin (cat. no. sc‑8432) (all 1:1,000; Santa Cruz Biotechnology, Inc

(11) P2X7 receptor regulates EMMPRIN and MMP‑9 expression through AMPK/MAPK signaling in PMA‑induced macrophagesMolecular Medicine ReportsJuly 16, 2018Lu Lin, Shanjun Huang, Zhouyang Zhu, Jibo Han, Zhengxian Wang, Weijian Huang, Zhouqing Huangcat. no. ab666, Abcam, Cambridge, MA, USA), extracellular signal‑regulated kinase (ERK)1/2 (cat. no. sc81457) or p‑ERK1/2 (cat. no. sc81492) (both 1:300 in TBST; Santa Cruz Biotechnology, Inc., Dallas, TX, USA)

(12) JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial MemoryThe Journal of neuroscience : the official journal of the Society for NeuroscienceApril 11, 2018Morel C, Sherrin T, Kennedy NJ, Forest KH, Avcioglu Barutcu S, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, et al.Cell Signaling Technologies, catalog #9197, RRID:AB_321277), ERK2 (1:1000, Santa Cruz Biotechnology, catalog #sc-81457, RRID: AB_1122619), JNK1/2 (Santa Cruz Biotechnology, catalog #sc-137019, RRID:AB_2140722), pJNK (Santa Cruz Biotechnology

(13) SHP2 acts both upstream and downstream of multiple receptor tyrosine kinases to promote basal-like and triple-negative breast cancerBreast Cancer ResearchDecember 1, 2016Fatimah Matalkah, Elisha Martin, Hua Zhao, Yehenew M. AgazieJose, CA, USA); anti-CBL (sc-1651), anti-pan-extracellular signal-regulated kinase 2 (anti-pan-ERK2; sc81457), and anti-ubiquitin (sc271289) from Santa Cruz Biotechnology (Santa Cruz, CA, USA); anti-β-actin (A5441)

(14) The novel model peptide, αAL14, regulates angiogenesis by inhibiting VEGFR 2-mediated signaling in HUVECsInternational Journal of OncologyOctober 1, 2016Nan-Hee Kim, Chang-Won Kang, Hye-Jin Go, Chan-Hee Kim, Nam Gyu Park, Gun-Do Kimand β-actin (1:1,000, #4970)) were purchased from Cell Signaling Technology Inc. and ERK2 (1:1,000, sc-81457) for western blot analysis was purchased from Santa Cruz Biotechnology Inc. (Dallas, TX, USA). Secondary

(15) HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signalingOncogeneAugust 29, 2013Zachary Hartman, Hua Zhao, Yehenew M. Agaziefrom Cell Signaling. The anti-c-CBL antibodies (SC-170 and SC-1651) and the anti-panERK2 antibody (SC-81457) were bought from Santa Cruz Biotechnology. Secondary antibodies conjugated with horseradish peroxidase

(16) Growth hormone releasing hormone induces the expression of nitric oxide synthaseJournal of Cellular and Molecular MedicineMay 1, 2011Nektarios Barabutis, Agnieszka Siejka, Andrew V. Schallyfrom Abcam (Cambridge, MA, USA) and the NFK50 (sc-1191), pNFK50 (sc-33022), β actin (sc-47778), ERK2 (sc-81457) and growth hormone-releasing hormone receptor (GHRHR) (sc- 10280) antibodies were from Santa Cruz Biotechnology

(17) Activation of mitogen-activated protein kinases by a splice variant of GHRH receptorJournal of Molecular EndocrinologyFebruary 1, 2010Nektarios Barabutis, Agnieszka Siejka, Andrew V Schally, Norman L Block, Renzhi Cai, Joseph L Varga(Restore Plus Western Blot Stripping Buffer, Thermo Scientific, Waltham, MA, USA) and probed for ERK2 (sc-81457, Santa Cruz Biotechnology) and b-actin (Santa Cruz Biotechnology). Plasmids and transfection The construction

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ERK 2 (12A4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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ERK 2 (12A4) Antibody from Santa Cruz Biotechnology, Inc.

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