Brilliant Violet 785™ anti-mouse CD4 100552 from BioLegend

Product Specs
ItemBrilliant Violet 785™ anti-mouse CD4
CompanyBioLegend
Price $273.00Supplier Page View Company Product Page
Catalog Number100552
Quantity50 µg
ApplicationsFC - Quality tested
Concentrationµg sizes: 0.2 mg/mLµL sizes: lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Conjugate/TagBrilliant Violet 785™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityMouse
IsotypeRat IgG2a, kappa
CloneRM4-5
HostRat
Antibody TypePrimary
ImmunogenBALB/c mouse thymocytes
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) A host-adapted commensal fungus from pet store mice drives type 2 immunity and cross-kingdom protectioniScienceAugust 21, 2026Geongoo Han, Rebecca Yunker, Mohammad H. Hasan, Alex Bruce, Kellie Baldaro, Jessica Pacia, Nicholas N. Jarjour, Lalit K. Beura, Shipra VaishnavaAB_2562039 BV570 anti-mouse CD4,Biolegend,Cat#: 100541; RRID: AB_10897943 BV785 anti-mouse CD4,Biolegend,Cat#: 100551; RRID: AB_11218992 BUV395 anti-mouse CD4,BD,Cat#: 568375; RRID: AB_3095981 PE anti-mouse CD8a,Biolegend,Cat#:

(2) Regulatory T cells establish an IL-10-IL10Rα immunometabolic checkpoint that limits HSL activation and lipolysisbioRxivJuly 13, 2026Ramazan Yildiz, Kajal Davi, Niki F. Brisnovali, James W.R. McMullen, Chung Hwan Cho, Khatanzul Ganbold, YoungUk Jang, Njeri Z.R. Sparman, Aidan Warnock, Gabriel Deards, et al.#105319), CD3-PE (BioLegend #100308), B220-BUV805 (Invitrogen #368-0452-80), CD4-BV785 (BioLegend #100552), CD8b-BUV737 (BD Bioscience #741811), CD25-BV421 (BioLegend #102043). Samples were then quenched with

(3) Interleukin-4-producing type 2 innate lymphoid cells in the lymph node promote proallergic Tfh13 cell differentiationImmunityMay 19, 2026DongUk Lee, Meng-Ping Lu, Priya Rajamanimuthu, Mrinmoy Das, Enxhi Ferraj, Courtney Fisher, Peri Matatia, Chun-Wei Chen, Raif S. Geha, Caroline L. Sokol, et al.N418),BioLegend,"Cat# 117335, RRID:AB_11219204" Brilliant Violet 785™ anti-mouse CD4 (clone: RM4-5),BioLegend,"Cat# 100552, RRID:AB_2563053" Brilliant Violet 711™ anti-mouse TCR β chain (clone: H57-597),BioLegend,"Cat# 109243,

(4) Ambient temperature regulates CD4+ T cell tonic T cell receptor signaling and responsivenessiScienceMay 15, 2026Keisuke Sawada, John Eom, Bree A. Mahoney-Sutherland, Traci E. Stankiewicz, Jarren R. Oates, Daniel A. Giles, Pablo C. Alarcon, Michelle S.M.A. Damen, Angela Cannata, Julie Hargis, et al.cat: 100536; RRID: AB_493701; final concentration: 5 μg/mL), CD4-BV785 (BioLegend; clone: RM4-5; cat: 100552; RRID: AB_2563053; final concentration: 2 μg/mL), CD5-PerCP (BioLegend; clone: 53-7.3; cat: 100616;

(5) An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicansNature CommunicationsMay 4, 2026Pallavi Kakade, Juan F. Burgueno, Shabnam Sircaik, Nicole O. Ponde, Jinke Li, Iuliana V. Ene, Jiwoong Kim, Shen-Huan Liang, Rebecca Yunker, Ipsita Dey, et al.antibodies for 30 min at 22 °C. Antibodies used to stain surface markers included CD4 Antibody (BioLegend, 100551), CD45 Monoclonal Antibody (eBioscience, 64-9459-42), CD45 Antibody (BioLegend, 147716), anti-mouse

(6) Agonistic anti-CD40 antibody treatment converts resident regulatory T cells into activated type 1 effectors within the tumor microenvironmentImmunityApril 14, 2026Vivien I. Maltez, Charu Arora, Kyle P. Gribbin, Breanna Caruso, Margaret E. Haerr, Rina Sor, Qiaoshi Lian, Katie E. Blise, Shamilene Sivagnanam, Rosalie C. Sears, et al.562283), CD4 (clone GK1.5, BUV805, BD Biosciences, Cat # 612900; or clone RM4–6, BV785, Biolegend, Cat # 100552), CD3e (clone 145–2C11, PE-Cy5, Biolegend, Cat # 100310), IFN-γ (clone XMG1.2, PE-Cy7, eBioscience,

(7) DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor ImmunityAdvanced ScienceMarch 29, 2026Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, et al.stained with fluorochrome‐conjugated antibodies against mouse CD45 (BioLegend, 103139), CD4 (BioLegend, 100552), CD8 (BioLegend, 100742), CD44 (BioLegend, 103032), CD62L (BioLegend, 104412), CD69 (BioLegend, 104536),

(8) IL10RB expression in cancer cells is associated with evolutionary changes to solidify treatment resistanceBJC RepMarch 13, 2026Chie Kudo-Saito, Hiroki Ozawa, Hiroshi Imazeki, Hitomi Masuda, Aki Takaiwa, Masayoshi Toyouraantibodies: anti-CD45-PE-Cy7 (BioLegend #103114), anti-CD3e-BUV496 (BD #612955), anti-CD4-BV785 (BioLegend #100552), anti-CD8-BUV395 (BD #563786), anti-DX5-APC-Cy7 (BioLegend #108920), anti-CD11b-BV711 (BioLegend #101242),

(9) Respiratory viral infections prime accelerated lung cancer growthCellMarch 11, 2026Wei Qian, Xiaoqin Wei, Andrew J. Barros, Xiangyu Ye, Haibo Zhang, Qing Yu, Samuel P. Young, Eric V. Yeatts, Yury Park, Chaofan Li, et al.Antibody",BioLegend,Cat# 124308; RRID AB_2073556 Brilliant Violet 785 anti-mouse CD4 Antibody,BioLegend,Cat# 100552; RRID AB_2563053 PE/Cyanine7 anti-mouse CD8a Antibody,BioLegend,Cat# 100722; RRID AB_312760 Brilliant Violet 510 anti-mouse CD3ε

(10) Dual phagocytosis-checkpoint blockade revitalizes immune surveillance in mouse models of glioblastomaNature CommunicationsMarch 9, 2026JongHoon Ha, Yifan Wang, Yifan Ma, Annette Wu, Shiyan Dong, Seong Dong Jeong, Jared L. Edwards, Mengyu Chang, Yen-Tzu Chang, Xiaotian Wang, et al.antibodies included: CD3 (clone 145-2C11, BioLegend, 100330, 1:100), CD4 (clone RM4-5, BioLegend, 100510 or 100552, 1:100), CD8 (clone 53-6.7, BioLegend, 100722 or 100744, 1:100), IFN-γ (clone XMG1.2, BioLegend, 505808,

(11) Meningeal macrophages regulate fibroblasts to influence meningeal lymphatic function following traumatic brain injuryTheranosticsMarch 4, 2026Xiaoming Guo, Yueli Zhu, Shiqi Gao, Yiwen Wu, Yuan HongBiolegend), anti-PDGFRα-PerCP/Cy5.5 (135914, Biolegend), anti-I-A/I-E-PE (107607, Biolegend), anti-CD4-BV785 (100551, Biolegend), anti-CD3e-FITC (11-0031-81, Thermo Fisher Scientific), anti-CD19-PE (561736, BD Biosciences),

(12) Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan PresentationSmallFebruary 1, 2026Negin Pournoori, Heela Sarlus, Dick J. Sjöström, Rohith Pavan Parvathaneni, Oommen P. Varghese, Vesa P. Hytönen, Robert A. Harris, Per H. Nilsson, Oommen P. Oommen100220, BioLegend) or CD3‐BV510 (clone 17A2, cat# 100233, BioLegend), CD4‐BV785 (clone RM4‐5, cat# 100551, BioLegend) or CD4‐Percp‐Cy5.5 (clone Gk15, cat# 100434, BioLegend), CD8‐PE‐CF594 (clone 53–6.7, cat#

(13) ANGPTL3 in the Peripheral Circulation Is Associated with Resistance to Anti-PD1 Therapy in Advanced Gastric CancerCancer Res CommunFebruary 1, 2026Chie Kudo-Saito, Hirokazu Shoji, Kengo Nagashima, Hiroshi Imazeki, Kai Tsugaru, Naoki Takahashi, Takeshi Kawakami, Yusuke Amanuma, Takeru Wakatsuki, Naohiro Okano, et al.AB_312979), anti-CD3e-BUV496 (BD Biosciences, #612955; RRID: AB_2870231), anti-CD4-BV785 (BioLegend, #100552; RRID: AB_2563053), anti-CD8a-BUV395 (BD Biosciences, #563786; RRID: AB_2732919), anti-DX5/CD49b-APC-Cy7

(14) A ribonucleotide carbohydrate system (iRNC) enhances antigen presentation and controls glioblastomaTheranosticsJanuary 14, 2026Hyung Shik Kim, Juhyun Oh, Jueun Jeon, Fan Fei, Sepideh Parvanian, Rainer Kohler, Christopher Garris, Ralph WeisslederMHC-I,BioLegend,APC,141606,25-D1.16 CD3epsilon,Flow,T cells,BioLegend,PE-Cy5,100309,145-2C11 CD4,Flow,CD4 T cells,BioLegend,BV785,100552,RM4-5 Antibodies used. IF: immunofluorescence; FLOW: Flow cytometry.

(15) CD4+ T Cells Mediate MHC-Deficient Tumor Rejection and Endothelial Cell ReprogrammingCancer Immunology ResearchJanuary 8, 2026Samuel I. Kim, Margaret E. Haerr, Maryam Al-Ghezi, Canping Chen, Yi Zhang, Jackie L. Phipps, Charu Arora, Kyle P. Gribbin, Gangmin Kim, Nune Markosyan, et al.Cat # 612900 or Spark PLUS UV395, Biolegend, Cat # 100496; or clone RM4–6, BV785, Biolegend, Cat # 100552), CD3e (clone 145–2C11, PE-Cy5, Biolegend, Cat # 100310), IFN-γ (clone XMG1.2, PE-Cy7, eBioscience,

(16) CD4+ T cells mediate MHC-deficient tumor rejection and endothelial cell reprogrammingCancer Immunol ResJanuary 8, 2026Samuel I. Kim, Margaret E. Haerr, Maryam Al-Ghezi, Canping Chen, Yi Zhang, Jackie L. Phipps, Charu Arora, Kyle P. Gribbin, Gangmin Kim, Nune Markosyan, et al.Cat # 612900 or Spark PLUS UV395, Biolegend, Cat # 100496; or clone RM4–6, BV785, Biolegend, Cat # 100552), CD3e (clone 145–2C11, PE-Cy5, Biolegend, Cat # 100310), IFN-γ (clone XMG1.2, PE-Cy7, eBioscience,

(17) Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signalingJCI InsightDecember 22, 2025Bridget N. Alexander, Soojin Kim, Kristen L. Wells, Maya J. Hunter, Kevin P. Toole, Scott M. Wemlinger, Daniel P. Regan, Andrew Getahun, Mia J. SmithFor T cell phenotypes, cells were stained with antibodies against, B220, CD3, CD4-BV785 (BioLegend, 100552); CD8-BV650 (BioLegend, 100742); CD44-AF647 (BioLegend, 103018); CD62L-PE (BioLegend, 104408); CD25-BV421(BioLegend,

(18) Combined ε-Toxin Nanovaccine with Enhanced Immunity for Effective Protection in a Murine ModelInt J NanomedicineNovember 18, 2025Dongxue Li, Li Tang, Xinyu Fang, Tingting Liu, Xi Luo, Jiaxin Li, Jing Wang, Yanwei Li, Bing Yuan, Jinglin Wang, et al.Fluor 700, 56–0451-82, Thermo Fisher), CD3 (PerCP-eFluor 710, 46–0032-82, Thermo Fisher), CD4 (BV785, 100552, Biolegend), CD8 (BV510,100752, Biolegend), CD44 (BV480, 566116, BD), CD62L (APC-Fire 750, 104450, Biolegend),

(19) Combined ε-Toxin Nanovaccine with Enhanced Immunity for Effective Protection in a Murine ModelInternational Journal of NanomedicineNovember 18, 2025Dongxue Li, Li Tang, Xinyu Fang, Tingting Liu, Xi Luo, Jiaxin Li, Jing Wang, Yanwei Li, Bing Yuan, Jinglin Wang, et al.Fluor 700, 56–0451-82, Thermo Fisher), CD3 (PerCP-eFluor 710, 46–0032-82, Thermo Fisher), CD4 (BV785, 100552, Biolegend), CD8 (BV510,100752, Biolegend), CD44 (BV480, 566116, BD), CD62L (APC-Fire 750, 104450, Biolegend),

(20) High Fat and Sugar Diet Increases Enteric cDC1 and Oral Antigen-Specific TregsJ Immunol ResOctober 28, 2025K. Fischer, O. Horno, B. Raposo, I. Godinho, H. Ribeiro, H. Veiga-Fernandes, M. Martínez-LópezCD3ε FITC,BioLegend,100306 Anti‐mouse CD3ε Biotin,BioLegend,100304 Anti‐mouse CD4 BV785,BioLegend,100551 Anti‐mouse CD4 BV421,BioLegend,100437 Anti‐mouse CD4 BV650,BioLegend,100555 Anti‐mouse CD40 PerCP

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(1)

1/14/2019The Antibody Identifies CD4+ Cells Very Well Robert YuanWe wanted to study CD4+ T cells in the diseased vs healthy state, so we used the antibody to stain CD4+ T cells in the lymph nodes. The antibody is clear and works well.
(1)

4/16/2018Staining Mouse Splenocytes With Anti-CD4 BV785 Adam GuessThis antibody was used to stain CD4+ cells in mouse splenocytes. It was chosen because it is a commonly used clone for CD4, B785 is bright and works well with other fluorophores in the staining panel,... Read Review
(1)

7/27/2016A Good Brilliant Violet Antibody for CD4 Mithun KhattarSince CD4 is a lineage marker, it doesn't really require a bright fluorophore like BV785 for detection. However, I used this antibody for preparing compensation controls for this channel. I was a bit ... Read Review

Brilliant Violet 785™ anti-mouse CD4 from BioLegend

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Brilliant Violet 785™ anti-mouse CD4 from BioLegend

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