STIM2 Antibody 4917S from Cell Signaling Technology

Product Specs
ItemSTIM2 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4917S
NCBI Full Gene Namestromal interaction molecule 2
ApplicationsWB, ICC, IF
ReactivityHu, Ms, Rt, Mk
ClonalityPolyclonal
Research AreaCa, cAMP and Lipid Signaling
Molecular Weight100
HostRabbit
TargetSTIM2
Quantity100 µl

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Ca 2+ influx through ER-plasma membrane contacts is required for brown fat thermogenesis and metabolic healthbioRxivMarch 26, 2026J Zhou, C Dogan, L L Artico, K Rodrigues, S Hakam, T Kim, V Xu, K Lapenta, M Kang, D M Jorgens, et al.chemiluminescence system (Bio-Rad). Antibodies used were STIM1 (Cell Signaling, 4916), STIM2 (Cell Signaling, 4917), α-Tubulin (Proteintech, 66031-1-Ig), β-Tubulin (Cell Signaling, 2146S), GAPDH (Cell Signaling, 5174S),

(2) STIM1 functionally couples to transient receptor potential ankyrin 1 contributing to nociceptionPainDecember 1, 2025Yixiao Mei, Hareram Birla, Bo Hyun Lee, Zhixiao Li, Vipin Rai, Isis Zhang, Xiaodong Huo, Anni Yi, Qiao Zhang, Daling Li, et al.rabbit anti-STIM1 (1:8000, Cat# D88E10, Cell Signaling Technology, Danvers, MA), anti-STIM2 (1:1000, Cat#4917 Cell Signaling Technology), anti-Orai1 (1:500, Cat#4281, ProSci, Poway, CA), anti-TRPA1 (1:1000, Cat#

(3) Postbiotics of Lacticaseibacillus paracasei CECT 9610 and Lactiplantibacillus plantarum CECT 9608 attenuates store-operated calcium entry and FAK phosphorylation in colorectal cancer cellsMolecular OncologyMay 1, 2024Alvaro Macias‐Diaz, Jose J. Lopez, Maria Bravo, Isaac Jardín, Waldo Luis Garcia‐Jimenez, Francisco J. Blanco‐Blanco, Rosario Cerrato, Juan A. Rosadoregion) was from Origiene (Herford, Germany). Rabbit polyclonal anti‐STIM2 antibody (catalog number 4917S) was from Cell Signaling Technology (Leiden, the Netherlands). Rabbit monoclonal anti‐FAK antibody (catalog

(4) Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathwaybioRxivOctober 10, 2023Trayambak Pathak, J. Cory Benson, Martin T. Johnson, Ping Xin, Ahmed Emam Abdelnaby, Vonn Walter, Walter A. Koltun, Gregory S. Yochum, Nadine Hempel, Mohamed TrebakRRID:AB_2629281" STIM1,Cell Signaling Technology,Cat# 4916; RRID:AB_2271287 STIM2,Cell Signaling Technology,Cat# 4917; RRID:AB_2198021 IP3R1,Yule Lab,NA IP3R2,Yule Lab,NA IP3R3,BD Biosciences,Cat# 610313; RRID:AB_397705 SERCA2,Cell Signaling Technology

(5) Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sitesCommunications biologyOctober 4, 2023Criado Santos N, Bouvet S, Cruz Cobo M, Mandavit M, Bermont F, Castelbou C, Mansour F, Azam M, Giordano F, Nunes-Hasler P.(sc-101267/1:100); Cell Signaling: mouse anti-c-myc antibody (9B11) (2276/1:100), rabbit anti-STIM2 (4917S/1:1000); Thermo: mouse anti-CD16-CD32 (Fc-Block, 14-0161-85, 1:200), rabbit anti-ORP5 (PA5-18221/1:500),

(6) Orai1 is an Entotic Ca(2+) Channel for Non-Apoptotic Cell Death, Entosis in Cancer DevelopmentAdvanced science (Weinheim, Baden-Wurttemberg, Germany)May 1, 2023Lee AR, Park CY.ACC‐061), Orai3 (Alomone, ACC‐065), STIM1 (Abnova, H00006786‐M01), STIM2 (Cell Signaling Technology, 4917S), p‐MLC2 (S19) (Cell Signaling Technology, 3671S), MLC (MilliporeSigma, M4401), GAPDH (proteintech,

(7) Increased interaction between endoplasmic reticulum and mitochondria following sleep deprivationBMC BiologyJanuary 4, 2023Amina Aboufares El Alaoui, Edgar Buhl, Sabrina Galizia, James J. L. Hodge, Luisa de Vivo, Michele Bellesianion channel 1 (VDAC1, Abcam #15895, 1:2000) or Stromal Interaction Molecule 2 (STIM2, Cell Signaling #4917, 1:1000) diluted in 1X PBS 0.1% Tween-20 with 0.5% non-fat dry milk. Next, membranes were rinsed 3 times

(8) NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progressionInternational journal of biological sciencesJanuary 1, 2023Sun R, He J, Xiang Q, Feng Y, Gong Y, Ning Y, Deng C, Sun K, Zhang M, Cheng Z, et al.α-Tubulin (#3873, Cell Signaling Technology), Na+/K+-ATPase (#3010, Cell Signaling Technology), SUMO2/3 (#4917, Cell Signaling Technology), Importin β (#51186, Cell Signaling Technology), BID ( #2002, Cell Signaling

(9) The STIM1/2-Regulated Calcium Homeostasis Is Impaired in Hippocampal Neurons of the 5xFAD Mouse Model of Alzheimer’s DiseaseInternational Journal of Molecular SciencesNovember 26, 2022Ksenia Skobeleva, Alexey Shalygin, Elena Mikhaylova, Irina Guzhova, Maria Ryazantseva, Elena KaznacheyevaUSA, T9026, 1:1000), STIM1 (Cell Signaling, Danvers, MA, USA, №5668, 1:1000), STIM2 (Cell Signaling №4917, 1:1000), Orai1 (Sigma SAB4200273, 1:500), Orai2 (ProSci, Poway, CA, USA, №4111, 1:300), TRPC1 (Alomone,

(10) The mammalian trafficking chaperone protein UNC93B1 maintains the ER calcium sensor STIM1 in a dimeric state primed for translocation to the ER cortexJournal of Biological ChemistryMarch 1, 2022Wen-An Wang, Nicolas Demaurexanti-STIM1 (1:2000 dilution; catalog no.: S6072; Sigma), rabbit anti-STIM2 (1:2000 dilution; catalog no.: 4917S; Cell Signaling), mouse anti-Orai1 (catalog no.: ab175040; Abcam), rabbit anti-calnexin (1:1000 dilution;

(11) The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signalingNature immunologyFebruary 1, 2022Concepcion AR, Wagner LE 2nd, Zhu J, Tao AY, Yang J, Khodadadi-Jamayran A, Wang YH, Liu M, Rose RE, Jones DR, et al.rabbit mAb (D2P2F, 1:1000), phospho-STING-Ser365 rabbit mAb (D8F4W, 1:1000), STIM2 rabbit polyclonal Ab (4917S, 1:1000, all from Cell Signaling Technology), a custom-made rabbit anti-LRRC8C polyclonal antibody that

(12) STIM1 Controls the Focal Adhesion Dynamics and Cell Migration by Regulating SOCE in OsteosarcomaInternational journal of molecular sciencesDecember 23, 2021Lin YS, Lin YH, Nguyen Thi M, Hsiao SC, Chiu WT.USA). Primary antibodies against STIM1 (Abcam, #ab108994, Waltham, MA, USA), STIM2 (Cell signaling, #4917s, Beverly, MA, USA), Orai1 (Santa Cruz, #sc-377281, Santa Cruz, CA, USA), Orai2 (Santa Cruz, #sc- 376749),

(13) Resolving macrophage polarization through distinct Ca(2+) entry channel that maintains intracellular signaling and mitochondrial bioenergeticsiScienceNovember 19, 2021Nascimento Da Conceicao V, Sun Y, Ramachandran K, Chauhan A, Raveendran A, Venkatesan M, DeKumar B, Maity S, Vishnu N, Kotsakis GA, et al.anti-TRPC3 (ThermoFisher, PA577307), anti-STIM1 (Cell Signaling, 5668S), anti-STIM2 (Cell Signaling, 4917S), anti-JNK (Cell Signaling, 9252), anti-pJNK (Thr81) (Cell Signaling, 2676), anti-NFκB (p65) (Cell Signaling,

(14) NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca(2+) entry in T cellsCell reportsAugust 24, 2021Wu B, Woo JS, Vila P, Jew M, Leung J, Sun Z, Srikanth S, Gwack Y.,Cell Signaling Technologies,Cat# 13643 STIM1,Cell Signaling Technologies,Cat# 5668S STIM2,Cell Signaling Technologies,Cat# 4917 Phospho-IkB,Cell Signaling Technologies,Cat# 9246 β-Catenin,Cell Signaling Technologies,Cat# 9562 Phospho-mTOR,Cell Signaling Technologies

(15) A Novel Modulator of STIM2-Dependent Store-Operated Ca2+ Channel ActivityActa NaturaeMay 7, 2021Anton Yu. Skopin, Andrey D. Grigoryev, Lyubov N. Glushankova, Alexey V. Shalygin, Guanghui Wang, Viktor G. Kartzev, Elena V. Kaznacheyevaустановке для переноса (Hoefer Pharmacia Biotech., Германия). Первичные антитела к STIM1 (Cell Signaling #4917, США), STIM2 (Cell Signaling #5668) и α-тубулину (Sigma-Aldrich #T6074, США) разводили в соотношении

(16) Presynaptic store-operated Ca²⁺ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stressNeuronApril 21, 2021Chanaday NL, Nosyreva E, Shin OH, Zhang H, Aklan I, Atasoy D, Bezprozvanny I, Kavalali ET.(L63F7),Cell Signaling,"Cat# 2895, RRID:AB_2089254" Rabbit polyclonal anti-STIM2,Cell Signaling,"Cat# 4917, RRID:AB_2198021" Rabbit monoclonal anti-STIM1 (D88E10),Cell Signaling,"Cat# 5668, RRID:AB_10828699" anti

(17) Omnitemporal choreographies of all five STIM/Orai and IP(3)Rs underlie the complexity of mammalian Ca(2+) signalingCell reportsMarch 2, 2021Emrich SM, Yoast RE, Xin P, Arige V, Wagner LE, Hempel N, Gill DL, Sneyd J, Yule DI, Trebak M.antibodies and dilutions were used: STIM1 (1:2000; 4916, Cell Signaling Technology), STIM2 (1:1000; 4917, Cell Signaling Technology), α-tubulin (1:5000; 3873, Cell Signaling Technology), GAPDH (1:5000; MAB374,

(18) STIM2 Mediates Excessive Store-Operated Calcium Entry in Patient-Specific iPSC-Derived Neurons Modeling a Juvenile Form of Huntington's DiseaseFrontiers in Cell and Developmental BiologyFebruary 2, 2021Vladimir A. Vigont et al.catalog no. ab109115, Abcam, USA), or primary polyclonal anti-STIM2 antibody (1:1,000; catalog no. 4917, Cell Signaling Technology) and peroxidaseconjugated goat anti-mouse (1:30,000; catalog no. A0168, Sigma), or

(19) Store-operated Ca²⁺ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migrationScientific reportsApril 22, 2020Bendiks L, Geiger F, Gudermann T, Feske S, Dietrich A.(Sigma A3854HRP, 1:10,000), anti-STIM1 (CellSignaling, #4916S, 1:1000), anti-STIM2 (CellSignaling, #4917S, 1:1000) and secondary anti-rabbit IgG peroxidase (POX)-antibody (Sigma A6154, 1:10000). Viability

(20) Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling NetworksCell reportsDecember 3, 2019Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, et al.RRID:AB_398003 STIM1,Cell Signaling Technology,5668; RRID:AB_10828699 STIM2,Cell Signaling Technology,4917; RRID:AB_2198021 AMPK pMOTIF,Cell Signaling Technology,5759; RRID:AB_10949320 Myc tag,Cell Signaling Technology

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7/12/2022Time Course Effect of Chemoattractant on STIM2 Expression Somasundaram RaghavanSTIM2 protein encoded by the STIM2 gene in humans. It is one of the member of stromal interaction molecule family. Stromal interaction molecules responsible for as Ca2+ sensors that sense changes in ... Read Review

STIM2 Antibody

STIM2 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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STIM2 Antibody from Cell Signaling Technology

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