PI3 Kinase Class III Antibody 3811S from Cell Signaling Technology

Product Specs
ItemPI3 Kinase Class III Antibody
CompanyCell Signaling Technology
Price $422.00 Inquire
Catalog Number3811S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetPIK3C3
HostRabbit
NCBI Gene AliasesVPS34, Vps34, hVps34
NCBI Full Gene Namephosphatidylinositol 3-kinase catalytic subunit type 3
ClonalityPolyclonal
Research AreaPI3K / Akt Signaling
Molecular Weight100

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K / AKT SignalingThe Kaohsiung Journal of Medical SciencesApril 1, 2026Xiu‐Jun Li, Ning Wang, Fan Jiang, Jie‐Cheng Yang, Yan‐Yun Wang, Kun Wangproteins overnight at 4°C: UBE3A (ab272168, 1:1000, Abcam), ITGB1 (PA5‐78028, 1:1000, Invitrogen), PI3K (#3811, 1:1000, Cell Signaling Technology, CST, Danvers, MA, USA), phosphorylated PI3K (p‐PI3K, PA5‐104853,

(2) PDK4-driven metabolic reprogramming enhances mesothelial cell invasion in colorectal cancer peritoneal metastasisActa Biochimica et Biophysica SinicaJanuary 28, 2026Lingyu Han, Qinyuan Zhang, Yuchen Wu, Wenqin Luo, Shaobo Mo, Hongsheng Fang, Qingguo Li, Renjie Wang, Guoxiang Cai, Weixing Dai(16443-1-AP; Proteintech), anti-p-ERK (28733-1-AP; Proteintech), anti-PI3 kinase class III (PI3K) (3811; Cell Signaling Technology) and anti-p-PI3K (4228; Cell Signaling Technology). Lipid oxidation assay

(3) The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1BThe Journal of cell biologyMay 5, 2025Lin YJ, Huang LT, Ke PY, Chen GC.cat#2679), anti-GAPDH (1:2,000, cat#5174), anti-ULK1 (1:1,000, cat#8054), anti-VPS34 (1:1,000, cat#3811), anti-Beclin1 (1:1,000, cat#3738), anti-phospho-p70 S6 Kinase (Thr389) (1:1,000, cat#9205), and anti-mTOR

(4) CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT PathwayCancer MedicineOctober 21, 2024Zhenfei Xiang, Senquan Yu, Yuxin Xu, Huacai Xiong, Danfei Hu, Qun Li, Zhenhua WuAF4650), p62 (Abcam, #ab109012), Beclin 1 (Abcam, # ab207612), PI3K (cell signaling technology, CST, # 3811), AKT (CST, #9272), and p‐AKT (CST, #9271). GAPDH (Abcam, # ab9485) was selected as the internal reference

(5) Hydrogen Sulfide Promotes Platelet Autophagy via PDGFR-α/PI3K/Akt Signaling in Cirrhotic ThrombocytopeniaJournal of Clinical and Translational HepatologyJuly 28, 2024Hua-Xiang Yang, Yang-Jie Li, Yang-Lan He, Ke-Ke Jin, Ling-Na Lyu, Hui-Guo DingAntibody (Cell Signaling Technology, #5114), PI3 Kinase Class III Antibody (Cell Signaling Technology, #3811); Phospho-PI3 Kinase Class III (Ser249) Antibody (Cell Signaling Technology, #13857), AKT monoclonal

(6) Hydrogen Sulfide Promotes Platelet Autophagy via PDGFR-α/PI3K/Akt Signaling in Cirrhotic ThrombocytopeniaJ Clin Transl HepatolJune 17, 2024Hua-Xiang Yang, Yang-Jie Li, Yang-Lan He, Ke-Ke Jin, Ling-Na Lyu, Hui-Guo DingAntibody (Cell Signaling Technology, #5114), PI3 Kinase Class III Antibody (Cell Signaling Technology, #3811); Phospho-PI3 Kinase Class III (Ser249) Antibody (Cell Signaling Technology, #13857), AKT monoclonal

(7) GRB2 is a BECN1 interacting protein that regulates autophagyCell Death & DiseaseJanuary 5, 2024Jetsy Montero-Vergara, Kira Plachetta, Lisa Kinch, Stephan Bernhardt, Kriti Kashyap, Beth Levine, Lipi Thukral, Martina Vetter, Christoph Thomssen, Stefan Wiemann, et al.phospho-ERK1/2 (T202/Y204) (9101 S), BECN1 (3738 S), SQSTM1/p62 (D5L7G) (88588 S), PI3 Kinase Class III/ VPS34 (3811 S), S6 Ribosomal Protein (5G10) (2217 S), phospho-S6 Ribosomal Protein (S240/244) (2215 S), p70 S6 Kinase

(8) Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritisArthritis research & therapyDecember 7, 2023Zhang X, He X, Zhang M, Wu T, Liu X, Zhang Y, Xie Z, Liu S, Xia T, Wang Y, et al.following primary antibodies were used: rabbit anti-PIK3R2 (PA5-84807, Thermo Fisher, USA), anti-PI3K (3811S, CST, USA), anti-p-PI3K (4228S, CST, USA), anti-AKT (4691S, CST, USA), anti-p-AKT (4060S, CST, USA),

(9) Increased IGFBP2 Levels by Placenta-Derived Mesenchymal Stem Cells Enhance Glucose Metabolism in a TAA-Injured Rat Model via AMPK Signaling PathwayInternational journal of molecular sciencesNovember 20, 2023Lee DH, Park H, You JH, Seok J, Kwon DW, Kim YR, Kim GJ.diluted 1:500, rabbit anti-FOXO3a (12829S, Cell Signaling Technology) diluted 1:1000, rabbit anti-PI3K (3811S, Cell Signaling Technology) diluted 1:2000, rabbit anti-AKT (phospho 927S, Cell Signaling Technology)

(10) Exploring the Anti-Cancer Effects of Fish Bone Fermented Using Monascus purpureus: Induction of Apoptosis and Autophagy in Human Colorectal Cancer CellsMolecules (Basel, Switzerland)July 27, 2023Chen YT, Chen SJ, Hu CY, Dong CD, Chen CW, Singhania RR, Hsieh SL.(1:1000 dilution, cat. no. ABC232, Millipore, Milford, CT, USA), Anti-PI3KIII (1:1000 dilution, cat. no. 3811, Cell Signaling Technology, Danvers, MA, USA), Anti-GAPDH (1:10,000 dilution, cat. no. GTX100118, GeneTex,

(11) E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNACancer Gene TherapyJuly 1, 2023Hao-Ming Shen, Di Zhang, Ping Xiao, Bin Qu, Yi-Fan Sun(ab4070, 1:500, Abcam), E-cadherin (ab231303, 1:1000, Abcam), Vimentin (ab92547, 1:1000, Abcam), PI3K (#3811, 1:1000, CST, Danvers, MA, USA), phosphorylated PI3K (p-PI3K, #4228, 1:1,000, CST), AKT (#9272, 1:1,000,

(12) Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding proteinCancer biology & therapyDecember 31, 2022Tang Y, Li K, Hu B, Cai Z, Li J, Tao H, Cao J.(Abcepta, Cat. no. Ap16249a), anti-PI3K rabbit polyclonal antibody (Cell Signaling Technology, Cat. no. 3811), anti-Phospho-PI3K rabbit polyclonal antibody (Cell Signaling Technology, Cat. no. 13857), anti-AKT

(13) Adenosine A1 receptor agonism protection mechanism in intestinal ischemia/reperfusion injury via activation of PI3K/Akt signalingExperimental and Therapeutic MedicineNovember 30, 2022Qian Xu, Zun Mao, Yi Yunfollowing primary antibodies (all from Cell Signaling Technology) at a 1:1,000 dilution: PI3K (cat. no. 3811S), Akt (cat. no. 9272S), phosphorylated (p)-Akt (cat. no. 9275S), p53 (cat. no. 9282S), p-p53 (cat. no.

(14) Autophagy modulates cell fate decisions during lineage commitmentAutophagyAugust 1, 2022Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A.RRID:AB_398152 ATG7/Apg7 antibody [EP1759Y],Abcam,"ab52472, RRID:AB_867756" PIK3C3/VPS34,Cell Signaling Technology,3811 RPS6KB1/p70S6 Kinase,Cell Signaling Technology,"9202, RRID:AB_331676" GABARAP,Abgent,AP1821a Secondary

(15) Validation of Two Activity Monitors in Slow and Fast Walking Hospitalized PatientsRehabilitation Research and PracticeMay 16, 2022Britt StÃ¦vnsbo Pedersen, Morten Tange Kristensen, Christian Ohrhammer Josefsen, Kasper Lundberg Lykkegaard, Line Rokkedal JÃ¸nsson, Mette Merete Pedersenwalkers∗∗∗N = 14,All gait speedsN = 35,Slow walkers∗∗N = 20,Fast walkers∗∗∗N = 14# Direct observation,7738∗,3811∗,3865∗,6397#,3758#,2446# "ActivPAL, single sensor",5096∗,1872∗,3200∗,3863#,1778#,2039# "SENS, single

(16) Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formationCell reportsNovember 23, 2021Twu WI, Lee JY, Kim H, Prasad V, Cerikan B, Haselmann U, Tabata K, Bartenschlager R.IgM,Echelon Biosciences,Cat#Z-P004 PI3 Kinase Class III antibody (VPS34),Cell Signaling Technology,Cat#3811 Beclin-1 Antibody,Cell Signaling Technology,Cat#3738 SARS-CoV-2 N protein,Sino Biological,Cat#40143-MM05 Anti-SARS

(17) Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporterMolecular psychiatryFebruary 1, 2021Harraz MM, Guha P, Kang IG, Semenza ER, Malla AP, Song YJ, Reilly L, Treisman I, Cortés P, Coggiano MA, et al.catalog number MAB369, were purchased from Millipore Sigma (Burlington, MA). Anti-VPS34, catalog number 3811S, and anti-phospho-VPS34 Ser249, catalog number 13857S, for western blot were purchased from Cell Signaling Technology

(18) WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signalingMolecular psychiatryFebruary 1, 2021Wang M, Tang C, Xing R, Liu X, Han X, Liu Y, Wang L, Yang C, Guo W.14821-1-AP), rabbit anti-VPS15 (1:1000, Abcam, ab128903), rabbit anti-VPS34 (1:1000, Cell Signaling, 3811 S), rabbit anti-Beclin1 (1:1000, MBL, PD017), rabbit anti-p-AKT (1:1000, Cell Signaling, 9018 S), rabbit

(19) DNase1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effectNeoplasmaJanuary 1, 2021Qing-Yun Chen, Lei Li, Da-Qin Suoantibody (#9271), AKT antibody (#9272), p21 antibody (#2947), p-cRaf antibody (#9427), and PI3K antibody (#3811) were purchased from Cell Signaling Technology. RNA extraction and reverse transcription-quantitative PCR

(20) NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myelomaMolecular oncologyApril 1, 2020Xia J, He Y, Meng B, Chen S, Zhang J, Wu X, Zhu Y, Shen Y, Feng X, Guan Y, et al.caspase‐3 (#9661S), USP7 (#4833S), ubiquitin (#3933S), HA‐tag (#3724S), Vps15 (#14580S), and Vps34 (#3811S) were obtained from Cell Signaling Technology (Danvers, MA, USA). Antibodies against NEK2 (sc‐55601),

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PI3 Kinase Class III Antibody

PI3 Kinase Class III Antibody from Cell Signaling Technology

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Cell Signaling Technology

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PI3 Kinase Class III Antibody from Cell Signaling Technology

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