G9a/EHMT2 (C6H3) Rabbit mAb 3306S from Cell Signaling Technology

Product Specs
ItemG9a/EHMT2 (C6H3) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3306S
Quantity100 µl
ApplicationsW, IF-IC, ChIP
ReactivityH, M, R, Mk
TargetG9a
HostRabbit
NCBI Gene AliasesBAT8, C6orf30, G9A, GAT8, KMT1C, NG36
ClonalityMonoclonal
NCBI Full Gene Nameeuchromatic histone lysine methyltransferase 2
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneC6H3
Molecular Weight160,180

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) The EHMT2-MBLAC2 axis suppresses ribosomal DNA transcription in response to nucleolar DNA damageCell Death & DiseaseMarch 18, 2026Chenyue Wang, Qiutian Lu, Lianbao Cao, Simeng Zeng, Zihan Gao, Yinglong Yang, Xiaowen Liu, Shanshan Gao, Chao Dong405 Anti-Mouse (Invitrogen, #A48255). Antibodies used for Western blotting experiments: EHMT2(CST, #3306S); EHMT2(Abclonal, #A19288); EHMT2(Proteintech, #66689-1-Ig); EHMT2(Selleck, #F0379); MBLAC2(Santa Cruz,

(2) Shugoshin 2A stabilizes heterochromatin complexes to suppress the 2-cell-like state in embryonic stem cellsStem Cell ReportsMarch 10, 2026Panpan Shi, Kairang Jin, Guoxing Yin, Lin Liuab12405), anti-HP1 (1:2000, Millipore, 05–689), anti-SETDB1 (1:2,000, Abcam, ab12317), G9A (1:2,000, CST, 3306S), GLP (1:1,000, R&D, PP-B0422-00), rabbit anti-H3K9me3 (1:2,000, Abcam, ab8898), rabbit anti-H3K27me3

(3) Role and mechanism of G9A-BMP2 in calcification-induced formation of unstable plaqueAtherosclerosis PlusFebruary 18, 2026Wenjuan Yang, Zheng Ma, Ying Cui, Shaobin Jiatemperature for 1 h. Afterwards, the samples were subjected to incubation with primary antibodies G9A (CST,3306S), anti-H3K9m2 (CST,46585), anti-RUNX2 (Abcam, ab23981), anti-BMP2 (Absin, abs159224), anti-SMα-actin

(4) Massive deciphering of the tissue nucleic acid-binding proteome via affinity chromatography integrated with data-independent acquisition-based proteomicsNucleic Acids ResearchNovember 20, 2025Huiyu Wang, Jianzheng Zhu, Suntao Li, Lu Zhang, Miao Guo, Jiaqi Zhao, Yan Zhang, Chengxi Cao, Shen Hu, Hua Xiaoantibodies: anti-H3 (1:1000; ab1791, Abcam), Anti-EHMT1 (1:1000; 118 542, Absin), Anti-EHMT2 (1:1000; 3306T, CST), Anti- H3K9me3 (1:1000; 13969T, CST), anti-H3K27me3 (1:1000; 9733S, CST), and anti-actin (1:1000;

(5) Targeting Intratumoral Copper Inhibits Tumor Progression via p62-Mediated EZH2 Degradation and Potentiates Anti-PD-1 Immunotherapy in Oral Squamous Cell CarcinomaAdvanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2025Lin X, Chen W, Li B, Zhao Z, Yu Z, Zhao XY, Zhou X, Feng Z, Lin C, Cao W.Phospho‐ERK1/2 (Thr202/Tyr204) (28733‐1‐AP, Proteintech, USA, dilution 1:1000, RRID: AB_2 881 202), G9a (#3306, CST, USA, dilution 1:1000, RRID: AB_2 097 647), ESET (66293‐1‐Ig, Proteintech, USA, dilution 1:1000,

(6) Requirements for establishment and epigenetic stability of mammalian heterochromatinMolecular CellSeptember 18, 2025Antonis Tatarakis, Harleen Saini, Juntao Yu, Wenzhi Feng, Carlos A. Pinzon-Arteaga, Danesh Moazedprotein G, 5 μg anti-SUV39H1 (Diagenode, 15410368) with protein G, 5 μg anti-G9a (Cell Signal Technology 3306S) with protein G and 5 μg anti-SUZ12 (Cell Signaling 3737S) with protein G. For histone modification

(7) Integrative proteogenomic characterization of Wilms tumorNat CommunAugust 19, 2025Cheng Cheng, Li Zhang, Xiaofeng Chang, Kai Chen, Tian He, Jia Shi, Fan Lv, Lijia Pan, Yangkun Wu, Qianqian Cheng, et al.Histone H3 (Cat No. 4499, 1:1000), Di-Methyl-Histone H3 (Lys9) (Cat No. 4658, 1:1000), and EHMT2 (Cat No. 3306, 1:1000) were purchased from Cell Signaling Technology (Beverly, USA). The results of Western Blot were

(8) The Histone Methyltransferases EHMT1 and EHMT2 Repress the Expression of Genes Related to Excitability and Cell Death in Oligodendrocyte ProgenitorsGliaJuly 1, 2025Mathilde Pruvost, Hye‐Jin Park, Chloé Habermacher, Meng Li, Maria Cecilia Angulo, Jia Liu, Patrizia CasacciaCHRM3, 1:1000, Proteintech 21978-1-AP; EHMT1, 1:2,000, R&D PP-B0422-00; EHMT2, 1:2,000, Cell Signaling 3306S; H3K9me2, 1:2,000, Abcam ab1220; H3K9me3, 1:2,000 Abcam ab8898; Histone H3 total, 1:2,000 Abcam ab1791;

(9) EHMT2-mediated R-loop formation promotes the malignant progression of prostate cancer via activating Aurora BClinical and translational medicineJanuary 1, 2025Zhang Y, Su M, Chen Y, Cui L, Xia W, Xu R, Xue D, Zhang X, Feng X.by immunoblotting. Primary antibodies for immunoblotting included EHMT2 (Cell Signaling Technology, 3306), α‐Tubulin (Cell Signaling Technology, 3873), phospho‐H3 S10 (Cell Signaling Technology, 53348), CUL3

(10) RNAi Knockdown of EHMT2 in Maternal Expression of Prader–Willi Syndrome GenesGenes (Basel)October 24, 2024Violeta Zaric, Hye Ri Kang, Volodymyr Rybalchenko, Jeffrey M. Zigman, Steven J. Gray, Ryan K. Butler(BioRad, Hercules, CA, USA). The membranes were then probed with primary antibody anti-EHMT2 antibody (#3306, Cell Signaling) at dilution 1:500 in EveryBlot Blocking Buffer and incubated overnight at +4 °C. The

(11) Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune ActivationMolecular Cancer TherapeuticsSeptember 4, 2024Lily L. Nguyen, Zachary L. Watson, Raquel Ortega, Elizabeth R. Woodruff, Kimberly R. Jordan, Ritsuko Iwanaga, Tomomi M. Yamamoto, Courtney A. Bailey, Francis To, Abigail D. Jeong, et al.immunoblotted for EHMT1 (Bethyl Laboratories, Cat. #A301–642A; dilution 1:500), EHMT2 (Cell Signaling, Cat. #3306; RRID:AB_2097647; dilution 1:1000), alpha-tubulin (Cell Signaling Cat. #3873; RRID:AB_1904178; dilution

(12) Exploring the Reactivity of Rigid 1-Azadienes Derived from Methylene γ-Lactams. Applications to the Stereoselective Synthesis of Spiro-γ-LactamsThe Journal of Organic ChemistryJuly 5, 2024Adrián López-Francés, Zuriñe Serna-Burgos, Xabier del Corte, Jesús M. de los Santos, Abel de Cózar, Javier Vicario(2 × CHAr), 116.8 (2 × CHAr), 107.2 (=CH), 64.3 (CHN), 21.0 (CH3), 20.8 (CH3) ppm. FTIR (neat) nmax: 3306 (NHst), 1684 (C=Ost), 1665 (C=Cst) cm–1. HRMS (ESI-TOF) m/z: [M + H]+, calcd for C24H23N2O 355.1810;

(13) Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loopsNucleic acids researchNovember 27, 2023Ma TS, Worth KR, Maher C, Ng N, Beghè C, Gromak N, Rose AM, Hammond EM.BD Biosciences: GRP78 (610979), HIF-1α (610958); Bethyl: KAP1 (A300-274A); Cell Signaling: CHK1-S345 (2341), G9a (3306), H3 (14269), H3K9me2 (4658), KAP-S824 (4127), p53-S15 (9284), PERK (3192); Invitrogen: V5 (R960-25);

(14) Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic ProgressionAdvanced ScienceOctober 1, 2023Qizhi Geng, Yue‐Yu Kong, Weizhe Li, Jianhao Zhang, Haoli Ma, Yuhang Zhang, Lin‐Tai Da, Yan Zhao, Hai‐Ning Ducommercial sources: a‐Flag antibody (F7425‐2MG) were purchased from Sigma‐Aldrich; a‐G9a/EHMT2 (C6H3, #3306S, D5R4R, #68851), a‐Plk1 (4513S) and a‐Cyclin E1(20808) antibodies were purchased from Cell Signaling Technology

(15) Rif1 Regulates Self-Renewal and Impedes Mesendodermal Differentiation of Mouse Embryonic Stem CellsStem Cell Reviews and ReportsJuly 1, 2023Cheng Liu, Peng Yu, Zongna Ren, Fang Yao, Li Wang, Guang Hu, Pishun Li, Quanyi Zhao39,155), H3K9ac (Millipore, 07-352), H3K27ac (Active motif, 31,933), Suv39H1 (CST, 8729), EHMT2 (CST, 3306). Data Analysis and Statistics Statistical analyses were carried out using GraphPad Prism 9.0 software.

(16) RBBP4 is an epigenetic barrier for the induced transition of pluripotent stem cells into totipotent 2C-like cellsNucleic Acids ResearchJune 23, 2023Wangfang Ping, Yingliang Sheng, Gongcheng Hu, Hongxin Zhong, Yaoyi Li, YanJiang Liu, Wei Luo, Chenghong Yan, Yulin Wen, Xinxiu Wang, et al.RBBP7 (Abcam, ab259957), KAP1 (Abcam, ab22553), CHD4 (Abcam, ab70469), G9a (Cell Signaling Technology, 3306), HP1α (Cell Signaling Technology, 2616), β-Actin (Sigma, A2228) and glyceraldehyde phosphate dehydrogenase

(17) BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibilityNucleic acids researchMay 22, 2023Guo J, Qiu J, Jia M, Li Q, Wei X, Li L, Pan Q, Jin J, Ge F, Ma S, et al.Cambridge, UK, #ab10135); YAP (Cell Signaling, Danvers, MA, #14074); G9a (Cell Signaling, Danvers, MA, #3306); H3K9me2 (Abcam, Cambridge, UK, #ab1220); Histone H3 (Cell Signaling, Danvers, MA, #4499); β-tubulin

(18) Euchromatic Histone Lysine Methyltransferase 2 Inhibition Enhances Carfilzomib Sensitivity and Overcomes Drug Resistance in Multiple Myeloma Cell LinesCancers (Basel)April 7, 2023Elisabetta Mereu, Damiano Abbo, Tina Paradzik, Michela Cumerlato, Cecilia Bandini, Maria Labrador, Monica Maccagno, Domenica Ronchetti, Veronica Manicardi, Antonino Neri, et al.SCB" P27/Kip1,mouse,"#610241, BD Biosciences" P53,mouse,"#2524S, Cell Signaling Technology" G9a/EHMT2,rabbit,"#3306S, Cell Signaling Technology" Histone H3,rabbit,#4499T Cell Signaling Technology Mono-methyl-histone

(19) A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expressionNature communicationsJanuary 12, 2023Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, Matsuoka S, Sonoda T, Niwa H, Sato S, et al.Evolution Capt software (M&S Instruments Inc.). Primary antibodies used were anti-G9a (1:1000, CST, #3306), anti–α-tubulin (1:5000, Abcam, ab18251), anti-H3K9me2 (1:3000, Abcam, ab1220), anti-H3 (1:5000, Abcam,

(20) Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotesCell & BioscienceDecember 1, 2022Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liuprimary antibody: H3K9me2 (Cell Signaling Technology, #4658, 1:100), G9a (Cell Signaling Technology, #3306, 1:100), and Tet3 (Abcam, #ab153724, 1:200) overnight at 4 °C. Zygotes were then incubated with Alexa

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G9a/EHMT2 (C6H3) Rabbit mAb

G9a/EHMT2 (C6H3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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G9a/EHMT2 (C6H3) Rabbit mAb from Cell Signaling Technology

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