Normal Human IgG Control 1-001-A from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNormal Human IgG Control
CompanyR&D Systems, a Bio-Techne Brand
Price $99.00Supplier Page View Company Product Page
Catalog Number1-001-A
Quantity1 mg
ApplicationsControl
Conjugate/TagUnconjugated
Format10 mM Sodium Phosphate, 0.85% (w/v) Sodium Chloride, pH 7.2 (PBS) with 5% trehalose and 0.05% (w/v) Sodium Azide
PurityProtein A or G purified
ReactivityHuman
TargetIgG
IsotypeIgG
HostHuman
Antibody TypeIsotype Controls
ImmunogenNormal human plasma (Donor plasma tested and found negative for HBsAg, HIV-1, HIV-2 and HCV antibodies by FDA approved tests)
NCBI Full Gene Nameimmunoglobulin heavy constant gamma 1 (G1m marker)
ClonalityPolyclonal
Storage? 12 months from date of receipt at -20 to -70 °C ? 6 months from date of receipt at 2 to 8 °C

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) MCM7 promotes liver fibrosis by transcriptionally regulating IL11 via the SHCBP1-RACGAP1-STAT3 axisCell death & diseaseAugust 11, 2025Wang C, Ye M, Xu T, Feng J, Zhang J, Yang W, Fang Q, Mei G, Zhao X, Liu K, et al.

(2) ICAM-1 autoantibodies detected in healthy individuals and cross-react with functional epitopesImmunoHorizonsMay 30, 2025Herman ML, Geanes ES, McLennan R, Greening GJ, Mwitanti H, Bradley T.(3369; Corning) overnight at 4 °C. Standards were prepared as followed prepared in duplicate: IgG (1-001-A, Lot#WAB0822071; Novus Biologicals) was diluted to 500 ng/mL followed by subsequent 1:2 dilutions until

(3) Defining gastric cancer ecology: the crucial roles of TREM2(+) macrophages and fibroblasts in tumor microenvironmentsCommunications biologyMarch 28, 2025Cao Q, Sun D, Tu C, Wang J, Fu R, Gong R, Xiao Y, Liu Q, Li X.the CXCL12/CXCR4 signaling axis, 300 μg/mL of CXCL12 antibody (AF-310-NA, R&D Systems, USA) or IgG (1-001-A, R&D Systems, USA) as a control is added to CAF-CM and incubated for 1 h. The treated medium is then

(4) Role of mast cell in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapyBMC CancerJanuary 17, 2025Masaaki Nishi, Shoko Yamashita, Chie Takasu, Yuma Wada, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Mitsuo ShimadaCMs were added to the culture medium at a ratio of 1:1. The same concentration of human IgG (cat. no. 1–001-A; R&D Systems, Inc.) was used as a control. Cell proliferation assay Cell proliferation assay procedures

(5) Clinical Implications of Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma: Cancer-Draining Blood Versus Peripheral BloodCancersAugust 22, 2024Joo DC, Kim GH, I H, Park SJ, Lee MW, Lee BE.

(6) Human iPSC-Derived Endothelial Cells Exhibit Reduced Immunogenicity in Comparison With Human Primary Endothelial CellsStem cells internationalJanuary 1, 2024Jia H, Moore M, Wadhwa M, Burns C.

(7) Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's diseaseBrain, behavior, and immunityMarch 1, 2023Erickson MA, Logsdon AF, Rhea EM, Hansen KM, Holden SJ, Banks WA, Smith JL, German C, Farr SA, Morley JE, et al.R&D Systems MAB105403 (5 μg/mouse)] and Control mice received an injection human IgG (R&D Systems #1–001-A, 8 μg/mouse). Other mice with separate controls (receiving 10 μg/mouse of mouse IgG1, Abcam) received

(8) Involvement of CD40-CD40L and ICOS-ICOSL in the development of chronic rhinosinusitis by targeting eosinophilsFrontiers in immunologyJanuary 1, 2023Zhou A, Shi C, Fan Y, Zheng Y, Wang J, Liu Z, Xie H, Liu J, Jiao Q.µg/ml; R&D Systems, Minneapolis, MN, USA, 169-CS-050). IgG (5 µg/ml; R&D Systems, Minneapolis, MN, USA, 1-001-A) was used as control. Cells were harvested for further analysis. Leukocytes were stained with an antibody

(9) Dll4 Inhibition Promotes Graft Retention in Fat Grafting Enriched with Adipose-Derived Stem CellsStem cells translational medicineJuly 20, 2022Lee CK, Park BY, Jo T, Park CH, Kim JH, Chung KJ, Kim YH, Park DY, Kim IK.after the fat graft (group 3). In the control group, an equal amount of control antibody (control IgG, 1-001-A, R&D Systems) was injected. Next, WT recipient mice were used to assess Dll4 expression, graft volume,

(10) Inhibition of the VEGF signaling pathway attenuates tumor‑associated macrophage activity in liver cancerOncology reportsApril 1, 2022Okikawa S, Morine Y, Saito Y, Yamada S, Tokuda K, Teraoku H, Miyazaki K, Yamashita S, Ikemoto T, Imura S, et al.CMs were added to the culture medium at a ratio of 1:1. The same concentration of human IgG (cat. no. 1-001-A; R&D Systems, Inc.) was used as a control. Cell proliferation assay Cell Counting Kit-8 (CCK-8) assay

(11) A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodellingNature cell biologyApril 1, 2022Abe Y, Sakata-Yanagimoto M, Fujisawa M, Miyoshi H, Suehara Y, Hattori K, Kusakabe M, Sakamoto T, Nishikii H, Nguyen TB, et al.binding assay Recombinant Fc chimera CD70 (SinoBiological, 10780-H01H) or human IgG (R&D systems, 1-001-A) was incubated with a single-cell suspension of FL haematopoietic cells for 10 min at 4 °C in RPMI with

(12) Schwann cells promote the migration and invasion of colorectal cancer cells via the activated NF-κB/IL-8 axis in the tumor microenvironmentFrontiers in oncologyJanuary 1, 2022Chen S, Chen M.human IL-8/CXCL8 antibody (cat. no. MAB208-100, R&D Systems, Inc.) or normal human IgG control (cat. no. 1−001−A, R&D Systems, Inc.) was added to CM with a final concentration of 0.2 μg/mL according to the neutralization

(13) GluA3 autoantibodies induce alterations in dendritic spine and behavior in miceBrain, behavior, and immunityOctober 1, 2021Scheggia D, Stanic J, Italia M, La Greca F, Zianni E, Benussi A, Borroni B, Di Luca M, Gardoni F.

(14) Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinomaNature communicationsJuly 2, 2021Sun YF, Wu L, Liu SP, Jiang MM, Hu B, Zhou KQ, Guo W, Xu Y, Zhong Y, Zhou XR, et al.

(15) High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted GlioblastomaCancersJanuary 20, 2021Oh JW, Oh YJ, Han S, Her NG, Nam DH.DMSO (#D2650) were purchased from Sigma Aldrich (St. Louis, MO, USA) and normal human IgG control (#1-001-A) was purchased from R&D Systems (Minneapolis, MN, USA). Hoechest33342 (#H3570) was purchased from Life Technologies

(16) High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted GlioblastomaCancersJanuary 20, 2021Oh JW, Oh YJ, Han S, Her NG, Nam DH.DMSO (#D2650) were purchased from Sigma Aldrich (St. Louis, MO, USA) and normal human IgG control (#1-001-A) was purchased from R&D Systems (Minneapolis, MN, USA). Hoechest33342 (#H3570) was purchased from Life Technologies

(17) Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced ApoptosisFrontiers in pharmacologyJanuary 1, 2021Ren Y, Wang X, Huang S, Xu Y, Weng G, Yu R.FAB347P), DR5 (cat no FAB6311P), DcR1 (cat no FAB6302P), DcR2 (cat no FAB633P), and human IgGs (cat no 1-001-A) were obtained from R&D Systems (Minneapolis, MN). Antibodies against phospho-JNK (Thr183/185) (cat

(18) Synthesis and Biological Evaluation of Novel Isoxazole-Amide Analogues as Anticancer and Antioxidant AgentsBioMed research internationalJanuary 1, 2021Eid AM, Hawash M, Amer J, Jarrar A, Qadri S, Alnimer I, Sharaf A, Zalmoot R, Hammoudie O, Hameedi S, et al.

(19) The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironmentOncotargetDecember 8, 2020Wada Y, Tokuda K, Morine Y, Okikawa S, Yamashita S, Ikemoto T, Imura S, Saito Y, Yamada S, Shimada M.

(20) An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularizationProceedings of the National Academy of Sciences of the United States of AmericaNovember 10, 2020Usui-Ouchi A, Aguilar E, Murinello S, Prins M, Gantner ML, Wright PE, Berlow RB, Friedlander M.20 mM Tris pH 6.8, 50 mM NaCl, and 2 mM DTT. One microgram (0.5 μL) of normal human IgG (R&D Systems 1-001-A) was used as a control. Downloaded by guest on November 15, 2021 1. N. D. Wangsa-Wirawan, R. A.

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2/11/2019Low Cost High Quantity of Isotype IgG for Experiments Mark EThis isotype IgG is the perfect control for multiple experiments that use human Fc-based reagents. This antibody has no background staining to any samples that have been tested.

Normal Human IgG Control

Normal Human IgG Control from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (67)

Reviews

Normal Human IgG Control from R&D Systems, a Bio-Techne Brand

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