UBC12 (D-4) Antibody sc-390064 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemUBC12 (D-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-390064
Quantity200 µg/ml
ApplicationsWB, IP, IF, ELISA
Conjugate/TagUnconjugated
Reactivitymouse, rat, human
ClonalityMonoclonal
CloneD-4
Hostmouse
Antibody TypePrimary Antibodies
NCBI Full Gene Nameubiquitin-conjugating enzyme E2M, ubiquitin conjugating enzyme E2 M
NCBI Gene AliasesUBC12, 2510040H03Rik, hUbc12, UBC-RS2, Ubc-rs2
TargetUBC12
FormatPurified
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Endothelial deletion of the neddylation E2 enzyme UBE2M inhibits tumor growth by promoting nonproductive angiogenesisJ Clin InvestJuly 21, 2026Xinyi Jiang, Jie Zhang, Li Zhou, Zonglin Li, Ningcong Sun, Xian Xu, Jisong Zhang, Yizhou Huang, Xue Zhang, Enguo Chen, et al.immunofluorescence: anti-CD31 (Servicebio, GB150217-100; R&D Systems, AF3628); anti-UBE2M (Santa Cruz Biotechnology, sc-390064); anti-DLL4 (Cell Signaling Technology, 2589; R&D Systems, AF1389); anti-STAT1 (Cell Signaling Technology,

(2) UBE2M deficiency in alveolar macrophages promotes emphysema through HIF-2α/MMP12 axisChinese Medical Journal Pulmonary and Critical Care MedicineJune 8, 2026Zhouyang Li, Dongyu Guo, Yong Wang, Haipin Chen, Na Li, Lingling Dong, Xuchen Xu, Yongchao Zhao, Yi Sun, Songmin Ying, et al.(mAb) (93882, Cell Signaling Technology, Danvers, MA, United States), monoclonal mouse anti-UBE2M (sc-390064, Santa Cruz, Dallas, TX, United States), phycoerythrin (PE)/cyanine7 anti-mouse F4/80 antibody (123113,

(3) Fetal Neuronal Vesicles in the Assessment of Perinatal Brain Dysfunction and Late-Onset Growth Restriction: A Pilot StudyInternational Journal of Molecular SciencesJanuary 9, 2026Vladislava Gusar, Natalia Kan, Anastasia Leonova, Vitaliy Chagovets, Victor Tyutyunnik, Anna Zolotareva, Nataliya Tyutyunnik, Ekaterina Yarotskaya, Gennadiy SukhikhUSA), NAE1 (APPBP1) (1:100, sc-390002, Santa Cruz Biotechnology, Santa Cruz, CA, USA), UBC12 (1:100, sc-390064, Santa Cruz Biotechnology, Santa Cruz, CA, USA), SUMO 1 (1:200; sc-5308, Santa Cruz Biotechnology, Santa

(4) Regulation of UBC12 expression and protein neddylation by PINK1 suggests a primate-specific functionZoological ResearchNovember 18, 2025Huang Wei, 暨南大学粤港澳中枢神经再生研究院, 广东省非人灵长类动物模型研究重点实验室, 中枢神经系统再生教育部重点实验室, 广东广州 510632, 中国, Guangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China, Xu Ting, Zhou Gong-Ke, Li Yu-Xuan, Lin Chuang-Zhen, Chen Xiu-Sheng, Zhang Tong, Jiang Liang, et al.(GTX108600, GeneTEX, USA), PRDX1 (sc137222, Santa Cruz, USA), UBC12 (14520-1-AP, Proteintech, USA; SC390064, Santa Cruz, USA), Rab14 (sc271401, Santa Cruz, USA), ATP5A (ab110273, Abcam, UK), NEDD8 (ET1702-84,

(5) E3 ligase Rbx1 orchestrates thymus development and fate determination of αβ-γδ T cellsResearch (Wash D C)July 10, 2025Di Wu, Qiuxu Chen, Mingjia Tan, YI SUNProteintech, 11905-1-AP; anti-Ube2f, Proteintech, 17056-1-AP; anti-Ube2m, Santa Cruz Biotechnology, sc-390064; and anti-β-actin, HuaBio, EM21002. Bulk RNA sequencing The CD4−CD8−CD44−CD25+CD28− DN3a cells were

(6) Non-Invasive Assessment of Neurogenesis Dysfunction in Fetuses with Early-Onset Growth Restriction Using Fetal Neuronal Exosomes Isolating from Maternal Blood: A Pilot StudyInternational journal of molecular sciencesFebruary 11, 2025Gusar V, Kan N, Leonova A, Chagovets V, Tyutyunnik V, Khachatryan Z, Yarotskaya E, Sukhikh G.(UniProt: Q13564) (1:100, sc-390002, Santa Cruz Biotechnology, USA), UBC12 (UniProt: P61081) (1:100, sc-390064, Santa Cruz Biotechnology, USA), SUMO 1 (UniProt: P63165) (1:200; sc-5308, Santa Cruz Biotechnology,

(7) Succinate dehydrogenase deficiency-driven succinate accumulation induces drug resistance in acute myeloid leukemia via ubiquitin-cullin regulationNature CommunicationsNovember 13, 2024Yifan Chen, Miao Xian, Wenwen Ying, Jiayi Liu, Shaowei Bing, Xiaomin Wang, Jiayi Yu, Xiaojun Xu, Senfeng Xiang, Xuejing Shao, et al.Antibodies against cullin 3 (#2759) was purchased from Cell Signaling Technology. Antibodies against UBC12 (SC-390064) was purchased from Santa Cruz Biotechnology. Antibodies against HA (db2603), GAPDH (db106) and β-actin

(8) A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancerSignal transduction and targeted therapyOctober 17, 2022Xu T, Ma Q, Li Y, Yu Q, Pan P, Zheng Y, Li Z, Xiong X, Hou T, Yu B, et al.

(9) Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In VivoBiomedicinesSeptember 21, 2022Wu MH, Hsu WB, Chen MH, Shi CS.

(10) UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11CancersSeptember 29, 2021Kim JH, Jung JH, Lee HJ, Sim DY, Im E, Park J, Park WY, Ahn CH, Shim BS, Kim B, et al.

(11) Rational discovery of molecular glue degraders via scalable chemical profilingNature chemical biologyNovember 1, 2020Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, et al.12916-1-AP), CUL5 (1:1000, Santa Cruz Biotechnology, sc-373822), UBE2M (1:1000, Santa Cruz Biotechnology, sc-390064), DDB1 (1:1000, Cell Signaling Technology, 5428S), cyclin K (1:5000, Bethyl, A301-939A), CDK12 (1:1000,

(12) Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexesNeoplasia (New York, N.Y.)April 1, 2020Yu Q, Hu Z, Shen Y, Jiang Y, Pan P, Hou T, Pan ZQ, Huang J, Sun Y.(abcam, ab124728), NAE1 (Cell signaling, 14321S), UBE2F (Santa Cruz, sc-398668), UBE2M (Santa Cruz, sc-390064), p21 (Cell signaling, 2947S), p27 (Cell signaling, 2552S), MCL1 (Cell signaling, 5453S), NRF2 (Santa Cruz

(13) Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein DegradationMolecular cellAugust 22, 2019Mayor-Ruiz C, Jaeger MG, Bauer S, Brand M, Sin C, Hanzl A, Mueller AC, Menche J, Winter GE.

(14) UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2FMolecular cellJune 21, 2018Zhou W, Xu J, Tan M, Li H, Li H, Wei W, Sun Y.

(15) Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3(SPOP) E3 ligase in cancer cellsNature communicationsJanuary 1, 0001"Zhou Q, Lin W, Wang C, Sun F, Ju S, Chen Q, Wang Y, Chen Y, Li H, Wang L, et al."(Ser222) (dilution: 1:1000); α-tubulin (Sigma, Clone AA13, T8203, dilution: 1:10000); UBE2M (Santa Cruz, sc-390064, dilution: 1:1000); UBE2F (ProteinTech, 17056-1-AP, dilution: 1:1000); Peroxidase AffiniPure Goat Anti-Rabbit IgG (H + L

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UBC12 (D-4) Antibody

UBC12 (D-4) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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UBC12 (D-4) Antibody from Santa Cruz Biotechnology, Inc.

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