RyR1 (D4E1) Rabbit mAb 8153S from Cell Signaling Technology

Product Specs
ItemRyR1 (D4E1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8153S
Quantity100 µl
ApplicationsW, IF-F
ReactivityH, M, R
TargetRyR1
IsotypeIgG
HostRabbit
NCBI Full Gene Nameryanodine receptor 1
NCBI Gene AliasesCCO, CMYP1A, CMYP1B, KDS, MHS, MHS1, PPP1R137, RYDR, RYR, RYR-1, SKRR
CloneD4E1
Molecular Weight~560
ClonalityMonoclonal
Research AreaCa, cAMP and Lipid Signaling

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosisThe Journal of PhysiologyNovember 1, 2025Alexis Ruiz, Sofia Benucci, Hervé Meier, Georg Schultz, Katarzyna Buczak, Christoph Handschin, Rodrigo C. G. Pena, Susan Treves, Francesco Zorzatoantibodies: rabbit D4E1 monoclonal anti‐RyR1 (Cell Signaling Technology, Danvers, MA, USA; catalog. no. 8153; 1:150 dilution in PBS), chicken anti‐GFP to visualize YFP‐Thy1 (Abcam; catalog. no. ab13970; 1:500

(2) Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosisJ PhysiolOctober 15, 2025Alexis Ruiz, Sofia Benucci, Hervé Meier, Georg Schultz, Katarzyna Buczak, Christoph Handschin, Rodrigo C. G. Pena, Susan Treves, Francesco Zorzatoantibodies: rabbit D4E1 monoclonal anti‐RyR1 (Cell Signaling Technology, Danvers, MA, USA; catalog. no. 8153; 1:150 dilution in PBS), chicken anti‐GFP to visualize YFP‐Thy1 (Abcam; catalog. no. ab13970; 1:500

(3) Site-1 protease is a negative regulator of sarcolipin promoter activityCommunications BiologySeptember 24, 2025Isha Sharma, Meredith O. Kelly, Katelyn Hanners, Ella S. Shin, Muhammad G. Mousa, Shelby Ek, Gretchen A. Meyer, Rita T. BrookheartSigma); His-tag (2365S, Cell Signaling Technology); calcineurin (2614S, Cell Signaling Technology); RYR1 (8153 T, Cell Signaling Technology). Densitometry analysis was performed using Bio-Rad Image Lab version 6.1. Real

(4) Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle diseaseActa Neuropathol CommunJanuary 16, 2025Samir R. Nath, Aneesha Dasgupta, Divyanshu Dubey, Eileen Kokesh, Grayson Beecher, Numrah Fadra, Teerin Liewuck, Sean Pittock, Jason D. Doles, William Litchy, et al.(1:200, ThermoFisher, MA3-922), TOMM20 (1:250, Santa Cruz, sc-17764), RYR1 (1:100, Cell Signaling, #8153). The following secondary antibodies were used for labeling: FITC Affinipure Donkey Anti-Mouse IgG (1:200,

(5) Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel DeficiencyAdvances in Experimental Medicine and BiologyJune 24, 2024Fan Yang, Hongwei Ma, Rekha Garg, Alfred Lewin, Xi-Qin Dingnumber,Dilutions used in immunoblotting (IB) or immunofluorescence labeling (IF) Ryr1,Cell Signaling,8153,1:500 (IB) M-opsin,EMD Millipore,AB5405,1:500 (IB) S-opsin,Dr. Muna Naash (University of Houston),,1:500

(6) The Effects of Aging on Sarcoplasmic Reticulum-Related Factors in the Skeletal Muscle of MiceInternational journal of molecular sciencesFebruary 10, 2024Kanazawa Y, Takahashi T, Nagano M, Koinuma S, Shigeyoshi Y.1:500), anti-SERCA2 antibodies (ab3625; Abcam, Cambridge, MA, USA; 1:500), anti-RyR1 antibodies (D4E1, #8153; Cell Signaling Technology, Danvers, MA, USA; 1:100), anti-JPH1 antibodies (40-5100; Thermo Fisher Scientific,

(7) New Findings: Hindlimb Unloading Causes Nucleocytoplasmic Ca(2+) Overload and DNA Damage in Skeletal MuscleCellsApril 3, 2023Yang H, Wang H, Pan F, Guo Y, Cao L, Yan W, Gao Y.(PKA),"1:1000, AF5450, Affinity Biosciences, Cincinnati, OH, USA" Ryanodine receptor 1 (RyR1),"1:1000, 8153S, Cell Signaling Technology, Danvers, MA, USA" Primary antibodies used in Western blot assay.

(8) A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCsCell reports. MedicineJune 15, 2021Uchimura T, Asano T, Nakata T, Hotta A, Sakurai H.antibody (rod-domain),Leica,NCL-DYS1; RRID: AB_442080 RYR1 antibody (D4E1),Cell Signaling Technology,8153; RRID: AB_2797637 Myogenin antibody (F5D),Santa Cruz,sc-12732; RRID: AB_627980 TBP antibody (D5C9H),Cell Signaling Technology

(9) Reduced membrane cholesterol content in skeletal muscle is not essential for greater insulin-stimulated glucose uptake after acute exercise by ratsApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolismeJune 1, 2021Wang H, Arias EB, Cartee GD.(pAMPKαThr172; #2531), anti-AMP-activated protein kinase-α (AMPKα; #5831), anti-ryanodine receptor 1 (RyR1; #8153), anti-insulin receptor (IR; #3025), anti-α-Tubulin (#2144) and anti-rabbit IgG horseradish peroxidase

(10) The Effects of Vitamin E on Non-proliferative Diabetic Retinopathy in Type 2 Diabetes MellitusInternational Journal of Diabetes and Clinical ResearchMay 23, 2021Ng En Yng, Chiew Yilynn, Phang Sonia Chew Wen, Ng Yeek Tat, Tan Gerald Chen Jie, Palanisamy Uma D, Ahmad Badariah, Kadir Khalid Abdulantibodies used for Western Blotting are listed in Supplementary Table S1: Anti-RyR1 (Cell Signaling, 8153S), anti-Cav1.1 (Santa Cruz sc-8160), anti-Calsequestrin-1 (Sigma, C-0743), anti-SERCA1 (Santa Cruz, sc-8093),

(11) A Low Vitamin A Diet Decreases Skeletal Muscle PerformanceJournal of Musculoskeletal Disorders and TreatmentMay 19, 2021Ruiz Alexis, Bachmann Christoph, Franchini Martina, Benucci Sofia, Zorzato Francesco, Treves Susanantibodies used for Western Blotting are listed in Supplementary Table S1: Anti-RyR1 (Cell Signaling, 8153S), anti-Cav1.1 (Santa Cruz sc-8160), anti-Calsequestrin-1 (Sigma, C-0743), anti-SERCA1 (Santa Cruz, sc-8093),

(12) Dual-process brain mitochondria isolation preserves function and clarifies protein compositionProceedings of the National Academy of Sciences of the United States of AmericaMarch 16, 2021Noterman MF, Chaubey K, Lin-Rahardja K, Rajadhyaksha AM, Pieper AA, Taylor EB.Cell Signaling Technology, 2020, https://www.cellsignal.com/products/primary-antibodies/ryr1-d4e1-rabbit-mab/8153). We next compared our protein localization results with three highly utilized protein localization

(13) Effects of Remimazolam and Propofol on Ca2+ Regulation by Ryanodine Receptor 1 with Malignant Hyperthermia MutationBioMed Research InternationalJanuary 4, 2021Tomoyuki Watanabe, Hirotsugu Miyoshi, Yuko Noda, Soshi Narasaki, Atsushi Morio, Yukari Toyota, Hiroshi Kimura, Keiko Mukaida, Toshimichi Yasuda, Yasuo M. TsutsumiTween (0.1%) containing 2% skim milk and incubated with monoclonal primary antibodies (RYR1 (D4E1), #8153, Cell Signaling Technology, Danvers, MA, USA) overnight at 4°C. Immunolabeled blots were visualized

(14) Gestational Hypoxia Inhibits Pregnancy-Induced Upregulation of Ca ²⁺ Sparks and Spontaneous Transient Outward Currents in Uterine Arteries Via Heightened Endoplasmic Reticulum/Oxidative StressHypertensionSeptember 1, 2020Xiang-Qun Hu et al.by dry milk, membranes were incubated with primary antibodies (1:300– 1000 dilution) against RyR1 (8153, Cell Signaling, Danvers, MA), RyR2 (AB9080, EMD Millipore, Billerica, MA), RyR3 (AB9082, EMD Millipore),

(15) A Temporal Examination of Cytoplasmic Ca^{2 +} Levels, Sarcoplasmic Reticulum Ca^{2 +} Levels, and Ca^{2 +} -Handling-Related Proteins in Different Skeletal Muscles of Hibernating Daurian Ground SquirrelsFrontiers in physiologyJanuary 1, 2020Wang Z, Zhang J, Ma XF, Chang H, Peng X, Xu SH, Wang HP, Gao YF.Protein name,Antibody details RyR1,"1:1000, 8153S, CST, United States" DHPR,"1:1000, SC-21781, Santa Cruz, United States" FKBP12,"1:1000, ab58072, Abcam,

(16) Priority Strategy of Intracellular Ca(2+) Homeostasis in Skeletal Muscle Fibers During the Multiple Stresses of HibernationCellsDecember 22, 2019Zhang J, Li X, Ismail F, Xu S, Wang Z, Peng X, Yang C, Chang H, Wang H, Gao Y.CST, 5668S, Danvers, MA, USA), ORAI1 (1:1000, Thermo, MA5-15776, Eugene, OR, USA), RyR1 (1:1000, CST, 8153S, USA), LETM1 (1:1000, CST, 14997S, USA), PMCA3 (1:1000, Abcam, ab3530, Cambridge, UK), SERCA1 (1:1000,

(17) Extraocular muscle function is impaired in ryr3 ^-/- miceThe Journal of general physiologyJuly 1, 2019Eckhardt J, Bachmann C, Sekulic-Jablanovic M, Enzmann V, Park KH, Ma J, Takeshima H, Zorzato F, Treves S.nitrocellulose. The following primary antibodies were used for Western blotting: rabbit anti-RYR1 (8153S; Cell Signaling), goat anti-Cav1.1 (sc-8160; Santa Cruz), rabbit anti-Cav1.2 (sc-25686; Santa Cruz)

(18) Pregnancy Increases Ca ²⁺ Sparks/Spontaneous Transient Outward Currents and Reduces Uterine Arterial Myogenic ToneHypertensionMarch 1, 2019Xiang-Qun Hu, Rui Song, Monica Romero, Chiranjib Dasgupta, Xiaohui Huang, Mark A. Holguin, VaShon Williams, Daliao Xiao, Sean M. Wilson, Lubo Zhangsites by dry milk, membranes were incubated with primary antibodies (1:1000 dilution) against RyR1 (8153, Cell Signaling, Danvers, MA), RyR2 (AB9080, EMD Millipore, Billerica, MA) or RyR3 (AB9082, EMD Millipore).

(19) circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinomaCell death & diseaseOctober 25, 2018Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, Zhu G, Liu Y, Bian Z, Xu W, et al.

(20) Lactate dehydrogenase activity drives hair follicle stem cell activationNature cell biologySeptember 1, 2017Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, et al.

Be the First to Write a Review!

RyR1 (D4E1) Rabbit mAb

RyR1 (D4E1) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (23)

Reviews

RyR1 (D4E1) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map