TM4SF1/L6 Antibody AF7514 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTM4SF1/L6 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF7514
ApplicationsWB, FCM, IHC
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant mouse TM4SF1, Ala116-Thr161, Accession # Q64302
ConcentrationLYOPH
PurityAntigen Affinity-purified
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
Antibody TypePrimary Antibodies
ReactivityHu, Ms
NCBI Gene AliasesL6, M3S1, H-L6, M3s1, TAAL6
NCBI Full Gene Nametransmembrane 4 superfamily member 1, transmembrane 4 L six family member 1
HostSheep
IsotypeIgG
TargetTM4SF1/L6
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse TM4SF1 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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Questions and Answers

Can this antibody be used to study TM4SF1 in esophageal squamous cell carcinoma?

Yes, the TM4SF1/L6 Antibody has been utilized in studies investigating its role in esophageal squamous cell carcinoma, where it was shown to promote cell adhesion, migration, and invasion through interaction with integrin α6, highlighting its relevance in cancer research.

Is this antibody effective for use in immunohistochemistry?

The TM4SF1/L6 Antibody has been cited in scientific literature for use in immunohistochemistry, demonstrating its capability to detect TM4SF1 expression in tissue samples, which is crucial for understanding its role in various biological contexts.

What species can this antibody detect, and is it suitable for human studies?

The TM4SF1/L6 Antibody is reactive to both mouse and human TM4SF1, making it suitable for studies involving both species, including research on human tissues and cell lines.

How does the TM4SF1/L6 Antibody contribute to understanding lung regeneration?

The antibody has been used to identify human alveolar epithelial progenitor cells, which express TM4SF1, in studies focused on lung regeneration. This highlights its potential as a tool for exploring regenerative medicine strategies in pulmonary research.

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Palmitoylation-mediated regulation of KAT2A promotes lung metastasis in breast cancerNature cell biologyApril 1, 2026Liu M, Vandekeere A, Liu XZ, Schenck S, Fernández-García J, Tricot T, Peng-Winkler Y, Demicco M, Broekaert D, Vermeire I, et al.553142), and stained with the appropriate antibody on ice for 15 min. Anti-mouse TM4SF1 (R&D systems, AF7514) and sheep IgG isotype control (R&D systems, 5-001-A) with anti-sheep 488 secondary (Abcam, ab150177)

(2) Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitorNatureMarch 8, 2018Zacharias WJ, Frank DB, Zepp JA, Morley MP, Alkhaleel FA, Kong J, Zhou S, Cantu E, Morrisey EE.anti-mouse Tm4sf1 antibodies were used to ensure specificity: Sheep anti-mouse Tm4sf1 (R&D systems, AF7514, 1:10) and Sheep IgG isotype control (R&D systems, 5-001-A, 1:10) with anti-Sheep 488 secondary (Abcam,

(3) TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6Cell death & diseaseJanuary 1, 0001"Hou S, Hao X, Li J, Weng S, Wang J, Zhao T, Li W, Hu X, Deng B, Gu J, et al."Cell Signaling Technology (Massachusetts, USA), anti-TM4SF1 antibodies used for WB and IHC were from R&D Systems (Catalog #AF7514, Minnesota, USA) and Novus Biologicals (Catalog #NBP1-76549, Colorado, USA), respectively; Mouse mAbs

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Mouse TM4SF1 Antibody