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Antibodies
Anti-PTP4A3/PRL-R antibody
Anti-PTP4A3/PRL-R antibody from Abcam
Be the first to write a review!
Citations:
(15)
Supplier Page
Supplier Page from
Abcam for
Anti-PTP4A3/PRL-R antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-PTP4A3/PRL-R antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab50276
Antibody Type
Primary
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
Isotype
IgG
Clonality
Polyclonal
Quantity
50 UL
Host
Rabbit
Conjugate/Tag
Unconjugated
Format
Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins
Concentration
9.4 mg/ml
Gene Name
PTP4A3
Reactivity
Human
Target
PTP4A3 / PRL-R
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Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (15)
(1)
The Helix-Loop-Helix motif of human EIF3A regulates translation of proliferative cellular mRNAs
PLOS ONE
September 28, 2023
Marina P. Volegova, Cynthia Hermosillo, Jamie H. D. Cate
ab13492
), anti-MET (
EMD Millipore
07–283
,
Abcam
ab51067
), anti-MYC (
Abcam
ab32072
), anti-PTP4A3 (
Abcam
ab50276
recognizes PRL-3), anti-
RPS19
(
Bethyl
A304-002A
), anti-Mouse IgG-HRP (A00160), anti-Rabbit IgG-HRP (NA934V).
(2)
Phosphatase regenerating liver 3 participates in Integrinβ1/FAK-Src/MAPK signaling pathway and contributes to the regulation of malignant behaviors in hepatocellular carcinoma cells
Journal of Gastrointestinal Oncology
April 29, 2023
Guobin Chen, Zhenzhen Zhang, Jinghuan Li, Chao Hu, Dongmei Gao, Jun Chen, Lan Zhang, Xiaoying Xie
method as detailed previously (21). Briefly, the primary antibody (polyclonal rabbit anti-human PRL-3,
ab50276
,
ABCAM
, Cambridge, UK) was diluted
1:400
in phosphate-buffered saline (Hyclone, Logan, Utah, USA) containing
(3)
Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3
PloS one
January 1, 2023
Smith CN, Kihn K, Williamson ZA, Chow KM, Hersh LB, Korotkov KV, Deredge D, Blackburn JS.
nanobody-beads complex for
incubation
at 4°C overnight with rocking. For commercial antibodies (
Abcam
,
ab50276
;
GeneTex
,
GTX100600
;
R&D Systems
,
MAB3219
; and
Santa Cruz Biotechnology
,
sc-130355
), 3 μg of each antibody
(4)
PRL-3 facilitates Hepatocellular Carcinoma progression by co-amplifying with and activating FAK
Theranostics
August 18, 2020
Qiming Zhou et al.
points, with other scores defined it low expression. The antibody against PRL-3 was diluted
1:100
(
ab50276
,
Abcam
, Cambridge, UK). Other antibodies used
for IHC
staining
included those against the proteins
FAK
(5)
Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway
Medical Science Monitor
November 12, 2018
Bing-Hui Li, Yang Wang, Chao-Yang Wang, Ming-Juan Zhao, Tong Deng, Xue-Qun Ren
membrane
was incubated with the specific primary PRL-3 antibody (anti-PTP4A3, dilution,
1: 500
; cat. no.
ab50276
;
Abcam
) overnight at 4°C.
GAPDH
served as an internal control, and the primary
GAPDH
antibody was bought
(6)
PRL-3 promotes gastric cancer peritoneal metastasis via the PI3K/AKT signaling pathway
in vitro
and
in vivo
Oncology letters
June 1, 2018
Zhang Y, Li Z, Fan X, Xiong J, Zhang G, Luo X, Li K, Jie Z, Cao Y, Huang Z,
et al
.
(7)
PRL-3 promotes breast cancer progression by downregulating p14ARF-mediated p53 expression
Oncology Letters
December 19, 2017
Hua Xie, Hao Wang
temperature, the
membrane
was incubated with primary antibodiesanti-PRL-3 (dilution,
1:500
; cat. no.
ab50276
;
Abcam
), anti-p53 (dilution,
1:500
; cat. no.
ab31333
;
Abcam
), anti-p14ARF (dilution,
1:500
; cat. no.
(8)
PRL‑3 increases the aggressive phenotype of prostate cancer cells in�vitro and its expression correlates with high-grade prostate tumors in patients
International Journal of Oncology
November 20, 2017
Donna R. Edwards, Krzysztof Moroz, Haitao Zhang, David Mulholland, Asim B. Abdel-Mageed, Debasis Mondal
against AR (cat. no.
06680
) was from
Millipore
(Billerica, MA, USA) and antibody against PRL-3 (cat. no.
ab50276
) was from
Abcam
(Cambridge, MA, USA). The secondary antibody, TX-Red conjugated goat anti-rabbit IgG
(9)
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
Journal of Translational Medicine
December 1, 2016
Esten N. Vandsemb, Helena Bertilsson, Pegah Abdollahi, Øystein Størkersen, Thea Kristin Våtsveen, Morten Beck Rye, Torstein Baade Rø, Magne Børset, Tobias S. Slørdahl
Dimethyl sulfoxide (DMSO
) controls were included since the
inhibitor
was dissolved in DMSO. The antibodies against PRL-3 (
ab50276
) and GAPDH were both from
Abcam
(Cambridge, UK).
Gene expression profiling
A total of 156 samples were
(10)
PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN
Oncology reports
October 1, 2016
Xiong J, Li Z, Zhang Y, Li D, Zhang G, Luo X, Jie Z, Liu Y, Cao Y, Le Z,
et al
.
fluoride (PVDF)
membranes
were purchased from Millipore (Bedford, MA, USA). PRL-3 antibody [anti-PTP4A3 (
ab50276
)] was purchased from
Abcam
(Cambridge, UK) which recognizes human PRL-3 and does not cross-react with
(11)
Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis
Cancer research
January 1, 2016
Cheng Xing, Xing-Xing Lu, Peng-Da Guo, Tong Shen, Shen Zhang, Xiao-Shun He, Wen-Juan Gan, Xiu-Ming Li, Jing-Ru Wang, Yuan-Yuan Zhao, Hua Wu, Jian-Ming Li
(12)
An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer
Gut
April 1, 2013
Yongxia Liu, Ping Zheng, Yuhong Liu, Tianhai Ji, Xunhua Liu, Su Yao, Xing Cheng, Ying Li, Lin Chen, Zhengquan Xiao, Jun Zhou, Jianming Li
(13)
Upregulation of Protein Tyrosine Phosphatase Type IVA Member 3 (PTP4A3/PRL-3) is Associated with Tumor Differentiation and a Poor Prognosis in Human Hepatocellular Carcinoma
Annals of Surgical Oncology
January 1, 2013
Abudureheman Mayinuer, Mahmut Yasen, Kaoru Mogushi, Gulanbar Obulhasim, Maimaiti Xieraili, Arihiro Aihara, Shinji Tanaka, Hiroshi Mizushima, Hiroshi Tanaka, Shigeki Arii
immunohistochemical
studies were performed. The primary antibody used was a polyclonal rabbit anti-human PTP4A3 (
ab50276
,
Abcam
, Cambridge, UK), diluted
1:400
in phosphate-buffered saline containing 1 % bovine serum albumin.
(14)
Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis
PloS one
January 1, 2012
Khapare N, Kundu ST, Sehgal L, Sawant M, Priya R, Gosavi P, Gupta N, Alam H, Karkhanis M, Naik N,
et al
.
(15)
PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness
British Journal of Cancer
November 18, 2008
D G Molleví, A Aytes, L Padullés, M Martínez-Iniesta, N Baixeras, R Salazar, E Ramos, J Figueras, G Capella, A Villanueva
PRL-3 (rabbit anti-PRL-3, Zymed Laboratories, Invitrogen, Carlsbad, MA, USA, and rabbit anti-PRL-3,
ab50276
Abcam
, Cambridge, UK), diluted
1 : 500
in phosphate-buffered saline (PBS). Reaction was visualised using
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Reviews
Be the First to Write a Review!
Anti-PTP4A3/PRL-R antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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