Anti-RAB7 antibody [Rab7-117] - Late Endosome Marker ab50533 from Abcam

Product Specs
ItemAnti-RAB7 antibody [Rab7-117] - Late Endosome Marker
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab50533
Domain/Region/Terminus7-117
Antibody TypePrimary
HostMouse, Nude mouse
CloneRab7-117
Quantity50 UL
ClonalityMonoclonal
IsotypeIgG2b
ApplicationsImmunocytochemistry, Western blot
Conjugate/TagUnconjugated
FormatPurified immunoglobulin
Concentration2.2 mg/ml
Gene NameRAB7A
ReactivityDog, Human, Mouse, Rat
TargetRAB7

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) MYL3 protects chondrocytes from senescence by inhibiting clathrin-mediated endocytosis and activating of Notch signalingNature CommunicationsOctober 4, 2023He Cao, Panpan Yang, Jia Liu, Yan Shao, Honghao Li, Pinglin Lai, Hong Wang, Anling Liu, Bin Guo, Yujin Tang, et al.mouse monoclonal anti-RAB5 (1:200, 3A4, ab66746, Abcam), mouse monoclonal anti-RAB7 (1:200, Rab7-117, ab50533, Abcam), rabbit monoclonal anti-HES1 (1:100, ARC0513, A0925, Abclonal). The following antibodies were

(2) EGFR-T790M Mutation-Derived Interactome Rerouted EGFR Translocation Contributing to Gefitinib Resistance in Non-Small Cell Lung CancerMolecular & cellular proteomics : MCPSeptember 1, 2023Wu PS, Lin MH, Hsiao JC, Lin PY, Pan SH, Chen YJ.ProteinTech. NEDD4L (A302-513A) and VTA1 (A304-828A) were purchased from Bethyl Laboratories, Inc. Rab7 (ab50533) for Western blot of Rab7-IP was purchased from Abcam. Normal mouse immunoglobulin G (IgG) and rabbit

(3) Glucocorticoid enhances presenilin1-dependent Aβ production at ER's mitochondrial-associated membrane by downregulating Rer1 in neuronal cellsRedox biologySeptember 1, 2023Choi GE, Park JY, Park MR, Yoon JH, Han HJ.USA). The antibodies of IP3R (#ab5804), TOMM20 (#ab56783), Aβ (#ab2539), APP (#ab32136), and Rab7 (#ab50533) were obtained from Abcam (Cambridge, MA, USA). The Rab5 antibody (#NB120-13253) and Rab7 antibody (#NBP1-87174)

(4) Role of Rab5 early endosomes in regulating Drosophila gut antibacterial responseiScienceAugust 18, 2023Manish Joshi, Annelise Viallat-Lieutaud, Julien Royet(1:500, Invitrogen, MA5-32053), Rabbit anti-Rab5 (1:500 Abcam, ab31261), Mouse anti-Rab7 (1:500, Abcam, ab50533), Rabbit anti-Lamp1 (1:500, Abcam, ab30687), Chicken anti-GFP (1:2000, Aveslabs, GFP-1020), Mouse anti-Prospero

(5) Structure and regulation of full-length human leucine-rich repeat kinase 1Nat CommunAugust 9, 2023Riley D. Metcalfe, Juliana A. Martinez Fiesco, Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson, Ping Zhangprimary antibody (Abcam cat. ab302494, diluted 1:1000), Rab7A (total) primary antibody (Abcam cat. ab50533, diluted 1:2000) and anti-LRRK1 primary antibody (Abcam cat. ab228666, diluted 1:2000). Membranes were

(6) Apolipoprotein E intersects with amyloid-β within neuronsLife Science AllianceAugust 1, 2023Sabine C Konings, Emma Nyberg, Isak Martinsson, Laura Torres-Garcia, Oxana Klementieva, Claudia Guimas Almeida, Gunnar K Gourasmonoclonal anti-CD140a,BD Biosciences,Cat#558774; RRID: AB_397117 Mouse monoclonal anti-Rab7,Abcam,Cat# ab50533; RRID: AB_882241 Rabbit monoclonal anti-S100β,Abcam,Cat#ab52642; RRID: AB_882426 Mouse monoclonal

(7) Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolismNature communicationsMay 24, 2023Van Acker ZP, Perdok A, Hellemans R, North K, Vorsters I, Cappel C, Dehairs J, Swinnen JV, Sannerud R, Bretou M, et al.1:1000 for WB), rabbit anti-N-terminal PLD3 (in-house generated29, 1:1000 for WB), mouse anti-Rab7 (ab50533, Abcam, 1:500 for WB), rabbit anti-SREBP2 (10007663, Cayman Chemical, 1:1000 for WB), rabbit anti-STING

(8) Rab10 regulates the sorting of internalised TrkB for retrograde axonal transporteLifeMarch 10, 2023Oscar Marcelo Lazo, Giampietro Schiavoanti-phosphorylated CREB,Abcam,Cat#ab32096; RRID:AB_731734,1:250 Antibody,Mouse monoclonal anti-Rab7,Abcam,"Cat#ab50533, RRID:AB_882241",1:200 Antibody,Rabbit polyclonal anti-Rab5,Abcam,Cat#ab13253; RRID:AB_299796,1:200 Antibody,Rabbit

(9) Stage of infection with Mycobacterium avium subsp. paratuberculosis impacts expression of Rab5, Rab7, and CYP27B1 in macrophages within the ileum of naturally infected cowsFrontiers in Veterinary ScienceFebruary 3, 2023Taylor L. T. Wherry, Mark Heggen, Adrienne L. Shircliff, Shankumar Mooyottu, Judith R. Stabel115-605-205; Jackson Labs) and MAP detected by AF488 (1:1,000, A11070; Invitrogen). Rab7 primary (1:100, ab50533; Abcam) was then incubated with the tissue, followed by an AF594 secondary antibody (1:250, A21145,

(10) Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolismJournal of Biological ChemistryFebruary 1, 2023Pearl Cherry, Li Lu, Su Yeon Shim, Vincent Ebacher, Waqas Tahir, Hermann M. Schatzl, Samia Hannaoui, Sabine Gilchpolyclonal anti-RILP (ab140188), rabbit polyclonal anti-Lamp1 (ab24170), mouse monoclonal anti-Rab7 (ab50533), and mouse monoclonal anti-EGFP (ab184601) antibodies were procured from Abcam. Rabbit monoclonal anti-Rab5

(11) Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1CancersAugust 23, 2022Park SS, Kim JI, Lee CH, Bae JH, Park JM, Choe EJ, Baek MC.CD63 (ab68418, Abcam), Alix (#2171, CST), Syntenin-1 (ab133267, Abcam), Rab11 (ab18211, Abcam), Rab7 (ab50533, Abcam), Rab27A (ab55667, Abcam), Rab27B (ab76779, Abcam), LC3 (NB600-1384, Novus, Stroudsburg, PA,

(12) Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanismJournal of cell scienceAugust 15, 2022Cohen B, Altman T, Golani-Armon A, Savulescu AF, Ibraheem A, Mhlanga MM, Perlson E, Arava YS.primary chicken anti-neurofilament heavy chain (NFH; 1:1000, ab72996 Abcam) and mouse anti-Rab7 (1:200, ab50533 Abcam) antibodies in blocking buffer overnight at 4°C, and then with fluorescent secondary antibodies

(13) Atorvastatin Enhances the Efficacy of Immune Checkpoint Therapy and Suppresses the Cellular and Extracellular Vesicle PD-L1PharmaceuticsAugust 9, 2022Eun-Ji Choe, Chan-Hyeong Lee, Ju-Hyun Bae, Ju-Mi Park, Seong-Sik Park, Moon-Chang BaekUSA), PD-L1 (13684, Cell Signaling Technology), Rab27a (ab55667, Abcam), Rab11 (ab18211, Abcam), Rab7 (ab50533, Abcam), pan Ras (sc-166691, Santa Cruz, Santa Cruz, CA, USA), Rap1A (sc-398755, Santa Cruz), p-B-Raf

(14) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancerBritish Journal of CancerJune 1, 2022Meera Patel, Kathryn A. F. Pennel, Jean A. Quinn, Hannah Hood, David K. Chang, Andrew V. Biankin, Selma Rebus, Antonia K. Roseweir, James H. Park, Paul G. Horgan, et al.mouse antibody (1:100, Abcam, ab27043), anti-Rab5 (1:100, Abcam ab66746) or anti-Rab7 (1:1000, Abcam, ab50533) before washing again in TBS. Tissues were incubated in 1:500 fluorescent secondary antibodies (AlexaFluor®

(15) The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the RetinaSSRN Electronic JournalMarch 29, 2022Vasileios Toulis, Sílvia García-Monclús, Carlos de la Peña-Ramírez, Rodrigo Arenas-Galnares, Josep F. Abril, Sokol V. Todi, Naheed Khan, Alejandro Garanto, Maria do Carmo Costa, Gemma Marfanyanti-EEA1 Abcam (Cambridge, UK) Cat# ab2900; RRID:AB_2262056 Mouse anti-RAB7 Abcam (Cambridge, UK) Cat# ab50533; RRID:AB_882241 Rabbit anti-Dynein-2 Abcam (Cambridge, UK) Cat# ab122525; RRID:AB_11133051 Alexa Fluor 633 Phalloidin

(16) Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neuronsNeuronMarch 16, 2022Goldsmith J, Ordureau A, Harper JW, Holzbaur ELF.antibody,Abcam,Ab92516 Rab11A Rabbit polyclonal antibody,Zymed,71-5300 Rab7 Mouse monoclonal antibody,Abcam,Ab50533 Rab5 Mouse polyclonal antibody,BD Biosciences,610281 EEA1 Mouse polyclonal antibody,BD Biosciences,610456 HSP60

(17) The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neuronsCellular and Molecular Life SciencesMarch 1, 2022Swati Mishra, Allison Knupp, Marcell P. Szabo, Charles A. Williams, Chizuru Kinoshita, Dale W. Hailey, Yuliang Wang, Olav M. Andersen, Jessica E. Youngmicrotubule-associated protein 2 (MAP2) at 1:1000 (ab92434; Abcam); Ras-related protein Rab-7a (Rab7) at 1:1000 (ab50533; Abcam); Ras-related protein Rab-11 (Rab11) at 1:250 (#610656; BD Biosciences); Lysosome-associated

(18) Assessment of intestinal macromolecular absorption in young piglets to pave the way to oral vaccination: preliminary resultsVeterinary research communicationsFebruary 1, 2022Deluco B, Wilson HL.antibody (Abcam Inc., Toronto, ON, Canada; ab96196) (1:250 dilution), anti-Rab7 antibody (Abcam Inc., ab50533) (1:200 dilution), and anti-LAMP-1 antibody (GeneTex, Irving, CA, USA; 4E9/11) (1:200 dilution). Slides

(19) Site-specific ubiquitination of MLKL targets it to endosomes and targets Listeria and Yersinia to the lysosomesCell death and differentiationFebruary 1, 2022Yoon S, Bogdanov K, Wallach D.(ab25630, 1:200), anti-human MLKL (ab184718, 1:200), anti-human Rab7 (ab 137029, 1:200), anti-mouse Rab7 (ab50533, 1:200) from Abcam, anti-mouse Rab5 (R7904, 1:200) from Sigma. Alexa Fluor 405-conjugated anti-mouse

(20) Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic CellsFrontiers in immunologyJanuary 1, 2022Ng L, Wang X, Yang C, Su C, Li M, Cheung AKL.Abcam) were incubated with 15 min samples; late endosome marker, Mouse anti-Rab7 (1:500) (Cat. No. ab50533, Abcam) and recycling endosome maker Rabbit anti-Rab11 (1:500) (Cat. No. ab36112, Abcam) were incubated

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Anti-RAB7 antibody [Rab7-117] - Late Endosome Marker from Abcam

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Anti-RAB7 antibody [Rab7-117] - Late Endosome Marker from Abcam

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