Trypsin 1/PRSS1 Antibody AF3848 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTrypsin 1/PRSS1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF3848
NCBI Gene AliasesTRY4, TRP1, TRY1, TRYP1
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen
TargetTrypsin 1/PRSS1
IsotypeIgG
Quantity100 ug (also 25 ug)
HostSheep
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
NCBI Full Gene Nameserine protease 1
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Trypsin 1/PRSS1, Ala16-Ser247, Accession # P07477
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Trypsin 1/PRSS1 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) Trypsin 2 and rhTrypsin 3 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Minigenes for heterologous expression of human and mouse cationic trypsinogenPloS oneJanuary 1, 2026Berke G, Sahin-Tóth M.membrane (catalog number IPVH00010, Sigma). The anti-PRSS1 sheep polyclonal antibody (catalog number AF3848, R&D Systems) was used at 1:5000 dilution. As secondary antibody, horseradish peroxidase (HRP)-conjugated

(2) Misfolding PRSS1 variant p.Ala61Val in a case of suspected intrauterine pancreatitisPancreatologyFebruary 1, 2025Máté Sándor, David S. Vitale, Zoltán Attila Nagy, Sherif Y. Ibrahim, Maisam Abu-El-Haija, Maria Lazou, Sandor Vajda, Miklós Sahin-Tóth22°C overnight and for 1 h, respectively. The anti-PRSS1 sheep polyclonal antibody (catalog number AF3848, R&D Systems) was used at 1:5000 dilution. As secondary antibody, horseradish peroxidase (HRP)-conjugated

(3) SARS-CoV-2 infection induces beta cell transdifferentiationCell metabolismAugust 3, 2021Tang X, Uhl S, Zhang T, Xue D, Li B, Vandana JJ, Acklin JA, Bonnycastle LL, Narisu N, Erdos MR, et al.Antibody,R&D Systems,Cat#MAB1268; RRID: AB_2301508 Trypsin 1/PRSS1 Antibody,NOVUS Biologicals,Cat#AF3848; RRID: AB_2171706 Cytokeratin 19 antibody,Abcam,Cat# ab7754; RRID: AB_306048 Human CD31/PECAM-1 Antibody,R&D Systems

(4) Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitisAmerican journal of physiology. Gastrointestinal and liver physiologyApril 1, 2016Balázs A, Hegyi P, Sahin-Tóth M.(Millipore, Bedford, MA) at 350 mA for 1 h. Trypsinogen was detected with a sheep polyclonal antibody (no. AF3848; R&D Systems) used at a dilution of 1:5,000 followed by horseradish peroxidase (HRP)-conjugated donkey

(5) Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell deathCell death & diseaseApril 10, 2014Athwal T, Huang W, Mukherjee R, Latawiec D, Chvanov M, Clarke R, Smith K, Campbell F, Merriman C, Criddle D, et al.antibodies used recognised as follows: HA: 16B12 (Cambridge Biosciences, Cambridge, UK), human PRSS1: AF3848 (R&D Systems, Abingdon, UK), β actin: AC-15 (Sigma, Poole, UK), α-tubulin DM1A (Sigma), α-smooth muscle

(6) Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitisGutFebruary 1, 2014Schnúr A, Beer S, Witt H, Hegyi P, Sahin-Tóth M.concentration), at 4 °C overnight. Trypsinogen was detected with a sheep polyclonal antibody (R&D Systems, #AF3848) used at a dilution of 1:5000 followed by horse-radish peroxidase (HRP)-conjugated donkey polyclonal

(7) Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutantsThe FEBS journalJune 1, 2013Geisz A, Hegyi P, Sahin-Tóth M.(final concentration), at 4 °C overnight. Trypsinogen was detected with a sheep polyclonal antibody (#AF3848, R&D Systems, Minneapolis, MN) used at a dilution of 1:2000 followed by horse-radish peroxidase (HRP)-conjugated

(8) Intragenic duplication: a novel mutational mechanism in hereditary pancreatitisPancreasMay 1, 2011Joergensen MT, Geisz A, Brusgaard K, Schaffalitzky de Muckadell OB, Hegyi P, Gerdes AM, Sahin-Tóth M.overnight; and incubated with sheep polyclonal antibody against human cationic trypsinogen (R&D Systems, #AF3848) at a dilution of 1:2000 for 1 h at room temperature; followed by incubation with horse-radish peroxidase

(9) Developmental History Provides a Roadmap for the Emergence of Tumor PlasticityDevelopmental cellJanuary 1, 0001"Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, et al."anti-PAX9 (1:500; ab28538, Abcam), goat anti-PDX1 (1:200; AF2419, R&D Systems), sheep anti-PRSS1 (1:250; AF3848, R&D Systems), goat anti-SOX2 (1:200; AF2018, R&D Systems), goat anti-SOX9 (1:200; AF3075, R&D Systems),

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Trypsin 1/PRSS1 Antibody

Trypsin 1/PRSS1 Antibody

Trypsin 1/PRSS1 Antibody

Trypsin 1/PRSS1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Trypsin 1/PRSS1 Antibody from R&D Systems, a Bio-Techne Brand

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