5-HT7 Antibody

Product Specs
Item5-HT7 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberNB100-56352
ImmunogenThis antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 13-28 of the rat 5-HT7R (AAA42134.1)
Concentration1.0 mg/ml
ReactivityCanine,Human,Mouse,Rat
ApplicationsFlow Cytometry,Western Blot,Simple Western,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
HostRabbit
Quantity0.1 mg (also 0.025 mg)
Target5-HT7
FormatPBS
PurityProtein G purified
Molecular Weight54 kDa
Research AreaGPCR, Neuronal Cell Markers, Neuroscience, Neurotransmission
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles
NCBI Full Gene Name5-hydroxytryptamine receptor 7
NCBI Gene Aliases5-HT7, 5Ht7
ClonalityPolyclonal

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: The 5HT7 antibody recognizes all described 5HT7 receptor splice variants.

Sizes Available: 0.1 mg (also 0.025 mg)

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Tryptophan hydroxylase 1 and 5-HT₇ receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signalingMolecular cancerNovember 21, 2016Gautam J, Banskota S, Regmi SC, Ahn S, Jeon YH, Jeong H, Kim SJ, Nam TG, Jeong BS, Kim JA.

(2) Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamicsFrontiers in behavioral neuroscienceJanuary 1, 2015Speranza L, Giuliano T, Volpicelli F, De Stefano ME, Lombardi L, Chambery A, Lacivita E, Leopoldo M, Bellenchi GC, di Porzio U, et al.

(3) Biphasic regulation of mammary epithelial resistance by serotonin through activation of multiple pathwaysThe Journal of biological chemistryJanuary 1, 0001"Pai VP, Horseman ND."

(4) Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT₇ ReceptorInternational journal of molecular sciencesJanuary 1, 0001"Tempio A, Niso M, Laera L, Trisolini L, Favia M, Ciranna L, Marzulli D, Petrosillo G, Pierri CL, Lacivita E, et al."

(5) Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell linesBritish journal of pharmacologyJanuary 1, 0001"Mahé C, Bernhard M, Bobirnac I, Keser C, Loetscher E, Feuerbach D, Dev KK, Schoeffter P."

(6) Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of QuetiapineInternational journal of molecular sciencesJanuary 1, 0001"Okada M, Fukuyama K, Motomura E."USA), connexin43 (C6219, 1:100, Sigma-Aldrich), 5-HT1AR (NBP2-21590, 1:00, Novus Biologicals), 5-HT7R (NB100-56352, 1:00, Novus Biologicals), Erk (AF1576, 10 μg/mL, R&D systems, Minneapolis, MN, USA), phosphorylated-Erk

(7) Blockade of 5-HT7 receptors reduces tactile allodynia in the rat"Pharmacology, biochemistry, and behavior"January 1, 0001"Amaya-Castellanos E, Pineda-Farias JB, Castañeda-Corral G, Vidal-Cantú GC, Murbartián J, Rocha-González HI, Granados-Soto V."

(8) The serotonin receptor 5-HT₇R regulates the morphology and migratory properties of dendritic cellsJournal of cell scienceJanuary 1, 0001"Holst K, Guseva D, Schindler S, Sixt M, Braun A, Chopra H, Pabst O, Ponimaskin E."

(9) Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43International journal of molecular sciencesJanuary 1, 0001"Shiroyama T, Fukuyama K, Okada M."(AF1576, 10 μg/mL, R&D systems, Minneapolis, MN, USA), pErk (AF1018, 5 μg/mL, R&D systems), 5-HT7R (NB100-56352, 1:50, Novus Biologicals) and 5-HT1AR (NBP2-21590, 1:100, Novus Biologicals) were diluted in an antibody

(10) Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptorBloodJanuary 1, 0001"León-Ponte M, Ahern GP, O'Connell PJ."

(11) Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctionsProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Stull MA, Pai V, Vomachka AJ, Marshall AM, Jacob GA, Horseman ND."

(12) TPH1 and 5-HT₇ Receptor Overexpression Leading to Gemcitabine-Resistance Requires Non-Canonical Permissive Action of EZH2 in Pancreatic Ductal AdenocarcinomaCancersJanuary 1, 0001"Chaudhary P, Guragain D, Chang JH, Kim JA."

(13) Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of ratsKorean journal of anesthesiologyJanuary 1, 0001"Cho SY, Ki HG, Kim JM, Oh JM, Yang JH, Kim WM, Lee HG, Yoon MH, Choi JI."

(14) Disruption to the 5-HT₇ Receptor Following Hypoxia-Ischemia in the Immature Rodent BrainNeurochemical researchJanuary 1, 0001"Wixey JA, Reinebrant HE, Chand KK, Buller KM."

(15) Brain regulatory T cells suppress astrogliosis and potentiate neurological recoveryNatureJanuary 1, 0001"Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T, Sakai R, Matsuo K, Nakayama T, Yoshie O, et al."

(16) The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal MorphologyMolecular neurobiologyJanuary 1, 0001"Volpicelli F, Speranza L, Pulcrano S, De Gregorio R, Crispino M, De Sanctis C, Leopoldo M, Lacivita E, di Porzio U, Bellenchi GC, et al."

(17) Sensitization of restraint-induced corticosterone secretion after chronic restraint in rats: involvement of 5-HT₇ receptorsNeuropharmacologyJanuary 1, 0001"García-Iglesias BB, Mendoza-Garrido ME, Gutiérrez-Ospina G, Rangel-Barajas C, Noyola-Díaz M, Terrón JA."primary antibodies raised in rabbit against either 5-HT7 receptors (1:1000; Novus Biologicals, cat. NB100-56352, Littleton, CO, USA), TPH (1:5000; mouse, rat and human TPH1 specific reactivity; Santa Cruz Biotech.,

(18) "Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor"International journal of molecular sciencesJanuary 1, 0001"Okada M, Matsumoto R, Yamamoto Y, Fukuyama K."USA). The antibodies of GAPDH (NB300-322, 1:100, Novus Biologicals, Littleton, CO, USA) and 5-HT7R (NB100-56352, Novus Biologicals) were diluted in an antibody diluent (ProteinSimple). 4.5. Data Analysis Where possible,

(19) Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gainBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJanuary 1, 0001"Fukuyama K, Motomura E, Shiroyama T, Okada M."

(20) Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cellsNeuropharmacologyJanuary 1, 0001"Mahé C, Loetscher E, Dev KK, Bobirnac I, Otten U, Schoeffter P."

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5-HT7 Antibody

5-HT7 Antibody

5-HT7 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (22)

Reviews

5-HT7 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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