MHC class II (IBL-5/22) Antibody sc-59322 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMHC class II (IBL-5/22) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-59322
Antibody TypePrimary Antibodies
Quantity100 µg/ml
CloneIBL-5/22
ApplicationsWB, IP, IF, FCM
Reactivitymouse
Conjugate/TagUnconjugated
Hostrat
FormatPurified
ClonalityMonoclonal
IsotypeIgG1
NCBI Full Gene Namehistocompatibility 2, class II antigen E alpha
NCBI Gene AliasesE-alpha-f, H-2Ea, H2-Ea-ps, I-Ealpha, Ia-3, Ia3, MHC-H2-Ea
TargetMHC class II

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic InvolutionAdvanced ScienceJuly 24, 2025Zhida Zhang, Yongqi Wu, Ke Hou, Yiwen Zhang, Lin Chen, Muyao Yang, Zhehui Jin, Yongchao Xu, Yingjie Zhang, Yinli Cai, et al.dark with either anti‐MHC class I antibody (sc‐59199, Santa Cruz, 1:50) or anti‐MHC class II antibody (sc‐59322, Santa Cruz, 1:50), together with Cy5‐conjugated Wisteria floribunda agglutinin (WFA, L‐1350, Vector Laboratories

(2) Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren's Syndrome Related Dry EyeInvestigative ophthalmology & visual scienceApril 1, 2025Wang B, Liang L, Zeng H, Yang X, Zhang R, Deng W, Wang X, Yuan J.anti-p63 antibody (Proteintech, 12143-1-AP, 1:200), anti-MHC-II antibody (Santa Cruz Biotechnology, sc-59322, 1:100), anti-F4/80 antibody (CST, 30325, 1:200), anti-Vimentin antibody (Santa Cruz Biotechnology,

(3) The Insulin-Producing Cells Generated from Rat Adipose Tissue Mesenchymal Stem Cells via Pdx1 Overexpression Activate an Immune Response both in Vitro and in VivoIran J Med SciFebruary 1, 2025Shadab Mohammadian, Seyed Javad Hosseni, Fereshte Negad Dehbashi, Dian Dayerantibodies included those against CD40 (ABIN6260623), CD80 (ABIN678683), MHC-I (ABIN6263246), and MHC-II (sc-59322, Santa Cruz Biotechnology Inc., USA). Membranes were incubated with a suitable mouse anti-rabbit IgG-HRP

(4) External stimulation induces the secretion of autophagosome-like vesicles by B cellsAutophagy ReportsDecember 31, 2023Yu-Diao Kuan, Chao-Yuan Tsai, Shuhei Sakakibara, Daron M. Standley, Hitoshi Kikutani(Cell signaling Technology, 9091; 1:1,000); rabbit anti-LC3 (Cell Signaling Technology, 2775; 1:1,000); MHCII (Santa Cruz, sc59322; 1:1,000); rabbit anti-SQSTM1/p62 (Cell Signaling Technology, 23214; 1:1,000); rabbit anti-Rab21 (Invitrogen,

(5) Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Improves Neurological Outcome and Reduces Microglial Reactivity in a Rodent Model of Global Transient StrokeInternational journal of molecular sciencesJuly 5, 2023Moya-Gómez A, Font LP, Burlacu A, Alpizar YA, Cardonne MM, Brône B, Bronckaers A.553142, BD Pharmingen, San Diego, CA, USA) for ant-inflammatory microglia and rat anti MHC II (1:50, sc-59322, Santa Cruz, Dallas, TX, USA) for pro-inflammatory microglia. Secondary antibodies were the same as

(6) Skin Wound following Irradiation Aggravates Radiation-Induced Brain Injury in a Mouse ModelInternational journal of molecular sciencesJune 27, 2023Xiao M, Li X, Wang L, Lin B, Zhai M, Hull L, Zizzo A, Cui W, Kiang JG.dilution), and NeuN (ab177487, 1:2000 dilution) were purchased from Abcam (Cambridge, MA, USA), MHC-II (sc59322, 1:200 dilution) from Santa Cruz Biotechnology, p16 (PA5-20379, 2 µg/mL) and from Invitrogen (Carlsbad,

(7) Pancreastatin inhibitor PSTi8 balances energy homeostasis by attenuating adipose tissue inflammation in high fat diet fed micePeptidesJanuary 1, 2023Goand UK, Verma S, Gupta AP, Garg R, Dadge S, Gayen JR.

(8) Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cellsGliaJune 1, 2022Zveik O, Fainstein N, Rechtman A, Haham N, Ganz T, Lavon I, Brill L, Vaknin-Dembinsky A.

(9) Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injuryJournal of neuroinflammationApril 29, 2022Van Broeckhoven J, Erens C, Sommer D, Scheijen E, Sanchez S, Vidal PM, Dooley D, Van Breedam E, Quarta A, Ponsaerts P, et al.in TBS. Primary antibodies, goat anti-Arg1 (1:50, sc-18354, Santa Cruz) and rat anti-MHCII (1:200, sc-59322, Santa Cruz), were dissolved in TBS containing 10% non-fat dry milk powder and were incubated overnight

(10) Protocol to assess the effects of dysfunctional human vascular smooth muscle cells on other brain cells using in vitro models of Alzheimer's diseaseSTAR protocolsMarch 18, 2022Alvarez KLF, Aguilar-Pineda J, Vera-Lopez KJ, Lino Cardenas CL.,Molecular Probes,P36962 ,, Antibodies,Antibodies,Antibodies ,, "iNOS, dilution 1:400",Abcam,Cat# ab15323 "MHCII, dilution 1:100",Santa Cruz biotechnology,Cat#sc59322 "IL-6, dilution 1:100",Santa Cruz biotechnology,Cat# sc-57315 "Secondary antibody AF488 , dilution

(11) Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer diseaseiScienceSeptember 24, 2021Aguilar-Pineda JA, Vera-Lopez KJ, Shrivastava P, Chávez-Fumagalli MA, Nieto-Montesinos R, Alvarez-Fernandez KL, Goyzueta Mamani LD, Davila Del-Carpio G, Gomez-Valdez B, Miller CL, et al.primary antibodies against CD68 (Santa cruz biotechnology, sc-20060) MHC-II (Santa Cruz biotechnology, sc-59322) and iNOS (Abcam, ab15323) were used at 1:100 concentrations. For the 2D immunofluorescence analysis

(12) Overexpression of cathepsin S exacerbates lupus pathogenesis through upregulation TLR7 and IFN-α in transgenic miceScientific reportsAugust 11, 2021Lee J, Jang S, Choi M, Kang M, Lim SG, Kim SY, Jang S, Ko J, Kim E, Yi J, et al.

(13) Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down SyndromeNeuronDecember 9, 2020Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, Bartolucci M, Varea E, Catelani T, Contestabile A, et al.,Santa Cruz Biotechnology,"Cat# sc-19992, RRID:AB_2134495" Rat anti-MHCII,Santa Cruz Biotechnology,"Cat# sc-59322, RRID:AB_831551" Rabbit anti-P2Y12,Thermo Fisher Scientific,"Cat# PA5-77671, RRID:AB_2736305" Rat

(14) IFN-γ regulates the transformation of microglia into dendritic-like cells via the ERK/c-myc signaling pathway during cerebral ischemia/reperfusion in miceNeurochemistry internationalDecember 1, 2020Zhang H, Zhang T, Wang D, Jiang Y, Guo T, Zhang Y, Zhu F, Han K, Mu L, Wang G.

(15) B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartmentsJournal of cell scienceDecember 20, 2019Hernández-Pérez S, Vainio M, Kuokkanen E, Šuštar V, Petrov P, Forstén S, Paavola V, Rajala J, Awoniyi LO, Sarapulov AV, et al.

(16) ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injuryBrain, behavior, and immunityAugust 1, 2019Sommer D, Corstjens I, Sanchez S, Dooley D, Lemmens S, Van Broeckhoven J, Bogie J, Vanmierlo T, Vidal PM, Rose-John S, et al.

(17) The Neuropeptides of Ocular Immune Privilege, α-MSH and NPY, Suppress Phagosome Maturation in MacrophagesImmunoHorizonsNovember 1, 2018Benque IJ, Xia P, Shannon R, Ng TF, Taylor AW.

(18) Effects of triptolide on the expression of MHC II in microglia in kainic acid‑induced epilepsyMolecular medicine reportsJune 1, 2018Sun Z, Du M, Lu Y, Zeng CQ.from Takara Biotechnology Co., Ltd. (Dalian, China). Rat monoclonal anti‑mouse MHC II antibody (cat. no. SC‑59322) and rabbit polyclonal anti‑mouse CIITA antibody (cat. no. SC‑48797) were purchased from Santa Cruz Biotechnology, Inc

(19) SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDLAutophagyJanuary 1, 2015Choi SH, Gonen A, Diehl CJ, Kim J, Almazan F, Witztum JL, Miller YI.

(20) Extracellular vesicles are key intercellular mediators in the development of immune dysfunction to allergens in the airwaysAllergyOctober 1, 2010Shin TS, Kim JH, Kim YS, Jeon SG, Zhu Z, Gho YS, Kim YK.

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MHC class II (IBL-5/22) Antibody

MHC class II (IBL-5/22) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MHC class II (IBL-5/22) Antibody from Santa Cruz Biotechnology, Inc.

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