Fig 1: Homozygous Myo7aR206H mutation could affect the expression of DPY19L2, FSIP2, DNAH8 and DNAH17 by IF staining and Co-IP. DPY19L2 and FSIP2 located in the acrosome and flagella, but no expression in the patient’s spermatozoa. DNAH8 and DNAH17 were expressed in the sperm flagella, but absence in the patient’s sperm flagella (scale bars: 5 µm). Co-IP, co-immunoprecipitation; DAPI, 4,6-diamidino-2-phenylindole; IF, immunofluorescence; IgG, immunoglobulin G.