Endomucin (V.7C7) Antibody sc-65495 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemEndomucin (V.7C7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-65495
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneV.7C7
Reactivitymouse, rat
ApplicationsWB, IP, IF, IHC(P), FCM
FormatPurified
Hostrat
Conjugate/TagUnconjugated
ClonalityMonoclonal
IsotypeIgG2a
NCBI Full Gene Nameendomucin
NCBI Gene Aliases0610012K22Rik, Muc14
TargetEndomucin

Questions and Answers

What species does this antibody work with, and how has it been utilized in research?

The Endomucin (V.7C7) Antibody is reactive with mouse and rat tissues. It has been shown to be effective in applications such as immunofluorescence, where it was used to stain endothelial cells in various studies, including those investigating bone regeneration and angiogenesis (, , ).

Can this antibody be used for immunohistochemistry, and what are some specific examples of its application?

Yes, the Endomucin antibody has been successfully used in immunohistochemistry. For instance, it was employed to analyze endothelial cell morphology and function in studies related to bone healing and the vascular niche in acute myeloid leukemia (, ).

How does the Endomucin antibody contribute to understanding endothelial cell behavior in pathological conditions?

The Endomucin antibody has been utilized to assess endothelial cell characteristics in various pathological contexts, such as in studies examining the effects of obesity on endothelial function and angiogenesis in diabetic models (, ). It helps elucidate the role of endothelial cells in conditions like osteoporosis and cancer.

What is the significance of using this antibody in studies focused on bone regeneration and vascularization?

The Endomucin antibody is crucial for identifying and characterizing type H endothelial cells, which are associated with enhanced angiogenesis and bone formation. Its application in studies has provided insights into the mechanisms of bone regeneration and the interplay between vascularization and osteogenesis (, ).

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Bo-Net: Deep learning-based model for automatic bone stromal cell segmentation of fluorescence microscopy imagesPLoS OneAugust 4, 2026Giorgio Allegri, Luca Pavirani, Sergio Barrios, Sofia Rosy Caterina Sorice, Giulia Alessandrelli, Luca Marsilio, Antonios Mikos, Pietro Cerveri, Stefano Casarin, Eleonora Dondossolaprimary antibodies diluted 1:200 in staining solution. Primary antibodies included rat anti-endomucin (sc-65495, Santa Cruz), rabbit anti-laminin 1 + 2 (ab7463, Abcam), goat anti-mouse alkaline phosphatase (AF2910,

(2) Photocontrolled biomimetic PEEK scaffold with black phosphorus-strontium ion cascade release for vascularized bone regenerationMaterials Today BioAugust 1, 2026Fang Guo, BingQian Wang, Xiaoning Su, Xingxing Lv, Shuo Huang, Yayuan Guo, Yang Xue, Changkui Liuused to detect the expression of vascular markers CD31 (Abcam ab24590, 1:200) and EMCN (Santa Cruz sc-65495, 1:100), as well as osteogenic markers Runx2 (CST 12556, 1:500) and OCN (Abcam 72026, 1:1000). All image

(3) Protocol for standardized minimally invasive mouse models of bisphosphonate-related and radiation-induced jaw osteonecrosisbioRxivJuly 2, 2026Zhangfan Ding, Jiayuan Zhang, Hanyu Liu, Abhishek Chandra, Makarand V Risbud, Anjali P Kusumbe, Junyu Chenkit,Servicebio,G1005-100ML DAPI,Sigma-Aldrich,D9542 Antibodies,Antibodies,Antibodies CD31,Abcam,ab24590 Endomucin,Santa Cruz Biotechnology,sc-65495 Sp7,Abcam,ab209484 Donkey anti-Mouse IgG (H+L) Alexa Fluor 488,Invitrogen,A-21202 Donkey anti-Rat IgG (H+L

(4) Angiogenin mediates cell-cell fusion as a mitochondrial RNA processing enzymeBone ResearchJune 29, 2026Ke Shen, Yixiang Zeng, Jiekang Wang, Kangping Song, Surendra Kumar, Peisong Gao, Guo-fu Hu, Xu Cao, Mei WanSignaling Technology, #11967, 1:200), anti-CD31 (R&D Systems, FAB3628G, 1:50), anti-Emcn (Santa Cruz, SC-65495, 1:50) primary antibodies at 4 °C overnight. Samples were then incubated with Alexa Fluor® 488, 594,

(5) Inherent tissue homeostasis of the juvenile metaphysis provides a foundation for osteosarcoma developmentNature CommunicationsJune 26, 2026Masato Saito, Fumie Nakasuka, Nao Sankoda, Yihan Wang, Jumpei Taguchi, Sho Ohta, Yosuke Yamada, Manabu Ozawa, Satoko Sakurai, Atsushi Kondo, et al.primary antibodies were used: rabbit anti-p-RPA (pS4/S8) (1:400; ab87277, Abcam), rat anti-EMCN (1:200; SC-65495, Santa Cruz), rabbit anti-OSX (1:500–1:750; ab209484, Abcam), rabbit anti-p21 (1:500–1:750; ab188224,

(6) Protocol for ultrafast immunolabeling and 3D imaging of whole organs and large tissuesSTAR ProtocJune 19, 2026Zhangfan Ding, Hanyu Liu, Junyu Chen, Anjali P. KusumbeTriton X-100,Sigma-Aldrich,T8787 Urea,VWR,28876.367 ,, Antibodies,Antibodies,Antibodies ,, VEGFR2,Abcam,ab11939 α-SMA,Sigma-Aldrich,C6198 Endoglin,R&D Systems,AF1320 CD8⍺,Abcam,ab237368 LYVE1,Abcam,ab14917 Endomucin,Santa Cruz Biotechnology,sc-65495 Donkey anti-Rat IgG Alexa Fluor 594,Thermo Fisher Scientific,A21209 Donkey anti-Goat IgG Alexa Fluor

(7) Loss of MCT1 mediated lactate uptake causes delayed endplate maturation and intervertebral disc degenerationCell Death & DiseaseJune 3, 2026Maria Tsingas, Konstantinos Tsingas, Mei Smyers, Wujuan Zhang, Aaron R. Goldman, Eulisa Lawrence, John A. Collins, Makarand V. Risbudab115730), MCT4 (1:100; Invitrogen; PA5-87977), COL X (1:500; Abcam; ab58632), EMCN (1:100; Santa Cruz; sc65495), TNAP (1:50; sc271431), COL 1 (1:100; Millipore Sigma; ABT123), ACAN (1:50; Millipore Sigma; AB1031),

(8) Intermittent parathyroid hormone employs autonomous and non-autonomous mechanisms to drive osteogenesis from Ebf3-expressing skeletal progenitor cellsbioRxivMay 28, 2026Byron S.K. Chan, Bingzi Dong, Majd George, Juwell Wu, Birol Ay, Daniel J. Brooks, Mary L. Bouxsein, Benjamin Z. Leder, Garyfallia Papaioannou, Karin Gustafsson, et al.incubation at 4°C with rat anti-endomucin (Emcn) monoclonal antibody (1:100, Santa Cruz Biotechnology, sc65495), rat anti-CD31 monoclonal antibody (1:100, Bio-Rad, MCA2388), rabbit anti-perilipin A/B polyclonal

(9) Argonaute-2 slicing of Rtl1 promotes skeletal muscle development and postnatal survivalbioRxivMay 27, 2026Nickolas Almodovar, Caroline Dunn, Benjamin Kleavelandat RT, incubated overnight at 4C with anti-Endomucin antibody (clone V.7C7, Santa Cruz Biotechnology SC-65495) and anti-RTL1 antibody (YZ2844)(Ito 2015), each diluted 1:200 in PBST (PBS and 0.05% Tween-20), washed

(10) Tie2 inhibition disrupts TMEM doorway function and reduces dissemination in pancreatic ductal adenocarcinomaJ Exp Clin Cancer ResMay 16, 2026Erika Pereira Zambalde, Lina A. Ariyan, Francisco Puerta-Martinez, Yu Qin Zhu, Priyanka Patil, Nicole C. Panarelli, Jiufeng Li, Yookyung Jung, Christian Adkisson, Jakeb Petersen, et al.and anti-CD68 (MO876; Dako) for human tumors. To visualize endothelial cells, we used anti-endomucin (SC-65495; Santa Cruz) for mouse and anti-CD31 (MO823; Dako) for human tumors. TMEM doorways were counted in 10

(11) Type E endothelial cells orchestrate embryonic skeletogenesis via chondrogenic priming of skeletal progenitorsJ Orthop TranslatMay 16, 2026Yang-Yang Li, Sha Huang, Ou Hu, Qin Qin, Pulin Yan, Peng Lin, Ying-Bo Wang, Huai-Jian Jin, Jian Wu, Yu-Tong Wu, et al.6.0), 120 °C for 10 min; Primary antibodies: Anti-CD31 (AiFang, SAF005, 1:100), Anti-EMCN (Santa Cruz, SC-65495, 1:100), Anti-Periostin (R&D, AF2955, 1:100), and Anti-COLI (Abclonal, A24112, 1:200). For labeling

(12) Endothelial von Hippel-Lindau gene deletion causes abnormal blood and lymphatic vasculature through ectopic activation of the HIF-CXCR4 axisDevelopmentMay 15, 2026Wenling Li, Koh Nakayama, Ryo Sato, Rina Shimada, Yoshiaki Kubota, Yoh-suke Mukouyamaas an arterial endothelial cell marker; rat anti-endomucin antibody (EMCN, Santa Cruz Biotechnology, sc-65495; 1:500) as a venous endothelial cell marker; rabbit anti-LYVE1 antibody (Abcam, ab14917; 1:200), rat

(13) A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's ProgressionAdvanced ScienceMay 10, 2026Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong(AF2535, R&D); Rat monoclonal antibodies, such as CD31 (65058‐1, Thermo Fisher Scientific), Endomucin (sc‐65495, Santa Cruz), Ly6c (ab54223, Abcam) and PODXL (MAB1556, R&D Systems); and Chicken polyclonal antibody

(14) High-fat diet feeding induces organ-specific vascular remodeling with distinct temporal dynamics in male miceCommunications BiologyMay 9, 2026Emmi Pakarinen, Satu Paavonsalo, Madeleine H. Lackman, Yelin Subashi, Hanna M. Ruddock, Sinem Karamananti-PDXL (1:400, R&D Systems, AF1556, RRID: AB_354858), rat anti-EMCN (1:500, Santa Cruz Biotechnology, sc-65495, RRID: AB_2100037), rabbit anti-ERG (1:1000, Abcam, ab92513, RRID: AB_2630401), and rabbit anti-p-H2AX

(15) Identification of synovial lymphatic system in the temporomandibular joint and their roles in arthritis and painNature CommunicationsApril 25, 2026Yang Shu, Qing Chang, Ziying Lin, Pao-Fen Ko, Jingyi Chen, Yuyueyang Qiu, Feixiang Chen, Zhen Zhao, Glenn Thomas Clark, Anette Vistoso Monreal, et al.(Invitrogen, PA5-36156), Ly6b (Bio-Rad, MCA771GT), Anti-GFP (Abcam, ab13970), and Endomucin (Santa Cruz, sc65495). Alexa Fluor 488/568/647 (Invitrogen) were used as secondary antibodies. DAPI (Invitrogen; Cat# 62248)

(16) EMT and cell cycle control invadopodia and metastasis in breast cancer via Filip1LResearch SquareApril 19, 2026Bojana Gligorijevic, Elizaveta Belova, Afrooz Jarrah, Gleb Abalakov, Adam Karamisections were immunolabeled with primary antibodies against endomucin (1:100; Santa Cruz Biotechnology, sc-65495), Tks5 (1:75; EMD Millipore, MABT336), and FILIP1L (1:100; Thermo Scientific, PA5–60251) diluted in

(17) Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian canceriScienceMarch 20, 2026Florian Laforêts, Panoraia Kotantaki, Samar Elorbany, Joseph Hartlebury, Joash D. Joy, Beatrice Malacrida, Rachel C. Bryan-Ravenscroft, Chiara Berlato, Erica Di Federico, John F. Marshall, et al.,Thermo Fisher Scientific,Cat# A32795; RRID: AB_2762835 Endomucin (V.7C7) PE conjugated,Santa Cruz Biotechnology,Cat# sc-65495; RRID: AB_2100037 F4/80 (D2S9R) XP® Rabbit mAb,Cell Signaling Technology,Cat# 25514; RRID: AB_2799771 "FOXP3 Monoclonal Antibody (FJK-16s), PE, eBioscience

(18) Panx3 deficiency in mice impairs bone fracture healing and causes transient hypoglycemia in neonatal animalsMolecular MedicineMarch 19, 2026Shan Jiang, Anke Baranowsky, Julia Luther, Brooke L. O’Donnell, Brent Wakefield, Clara Bassen, Mona Neven, Gesine Eis-Janzyk, Michael Amling, Silvia Penuela, et al.primary antibodies anti-CD31-PECAM (1:200, #AF3628, R&D Systems, Minneapolis, USA) and Endomucin (1:100, #sc-65495, Santa Cruz Biotechnology, California, USA) were incubated overnight at 4 °C. After washing, the sections

(19) Prussian blue analogue-mineralized ginseng-derived vesicles promote PPARγ nuclear translocation to suppress tumor vasculogenic mimicry and reverse the immunosuppressive microenvironmentJournal of NanobiotechnologyMarch 18, 2026Chaoqin Guo, Xiaoyan Zhang, Qiyi Liu, Xinxiu Shi, Xu Han, Qingqing Qiao, Yinan Li, Jingxia Han, Xiaoqing Chang, Yunlong Zhao, et al.the presence and extent of VM in tumors. Briefly, the tissue sections were first stained with EMCN (sc-65495, Santa Cruz Biotechnology, USA) immunohistochemical staining, treated with sodium periodate for 10 min,

(20) Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male miceBone ResMarch 11, 2026Antoine Babuty, Javier Muñoz-Garcia, Olivier D. Christophe, Laurie Fradet, Manon Taupin, Denis Cochonneau, Emilie Ollivier, Frank Driessler, Claudia Lange, Oleksandr Boychenko, et al.antibodies were added at the corresponding concentration and incubated at 4 °C for 12 h. Endomucin (V.7C7, sc-65495, Santa Cruz Biotechnology, Dallas, TX) dilution 1/50. NG2 (546930, MA5-24247, Invitrogen, Waltham, MA)

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1/5/2022Great Endomucin Antibody MASNSEN CHERIEFWe used this antibody on several tissues. It worked very well and consistently.

Endomucin (V.7C7) Antibody

Endomucin (V.7C7) Antibody from Santa Cruz Biotechnology, Inc.

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Endomucin (V.7C7) Antibody from Santa Cruz Biotechnology, Inc.

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