Fig 1: Kaplan–Meier curves of cancer-specific survival time correlated with SIRT1, DBC1, H4K16Ac, H3K9Ac, and p53 expression. (A) Kaplan–Meier survival curves showed high SIRT1 expression to be a worse prognostic indicator with statistical significance. (B) Kaplan–Meier survival curves demonstrated that high DBC1 expression was a significant favorable prognostic indicator. (C) Kaplan–Meier survival curves indicated SIRT1 (-) and DBC1 (+) to be favorable prognostic indicator. (D) Kaplan–Meier survival curves showed that the SIRT1 (-) and H4K16Ac (+) group had very favorable prognosis. (E) There was a close tendency (P = 0.051) between SIRT1 (-) and H3K9Ac (+) versus SIRT1 (+) and H3K9Ac (-). (F) Kaplan–Meier survival curves showed that the SIRT1 (+) and p53 (+) group had a worse prognosis.