FOXP3 (2A11G9) Antibody sc-53876 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemFOXP3 (2A11G9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53876
NCBI Gene AliasesXPID, AIID, DIETER, JM2, IPEX, PIDX, sf, scurfin
Quantity200 µg/ml
Clone2A11G9
ApplicationsIP, IF, IHC(P), FCM, ELISA
ClonalityMonoclonal
Conjugate/TagUnconjugated
FormatPurified
NCBI Full Gene Nameforkhead box P3
IsotypeIgG2a
TargetFOXP3
ReactivityHu, Ms, Rt
Hostmouse
Antibody TypePrimary Antibodies

Questions and Answers

What species does this FOXP3 antibody work with in experiments?

The FOXP3 (2A11G9) antibody has been shown to be reactive with mouse, human (Homo sapiens), and rat species.

In what types of applications has this antibody been utilized according to the literature?

This antibody has been utilized in various applications including ELISA, flow cytometry (FCM), immunofluorescence (IF), immunohistochemistry on paraffin-embedded sections (IHC-p), and immunoprecipitation (IP).

Can you provide an example of how this antibody has been used in a specific study?

In the study by Da Silva et al. (2017), the FOXP3 antibody (sc-53876) was used in immunohistochemistry to analyze the expression of Qa-2 in inflammatory and neoplastic cells during solid Ehrlich tumor development, demonstrating its utility in cancer research.

How has this antibody been applied in the context of T cell research?

The FOXP3 antibody has been used to detect regulatory T cells in various studies, such as in the research by Wang et al. (2018), where it was employed to identify Treg cells in chronic hepatitis B patients, highlighting its relevance in immunological studies.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Enhanced ocular delivery of tacrolimus via cationic nanoliposomes: Mitigating inflammation and rebalancing Th17/Treg responses in dry eye diseaseMaterials Today BioJune 1, 2026Lirui Liu, Dan Chen, Siting Sheng, Xueqi Lin, Huiling Zhao, Chujun Liu, Xiang Chen, Yang Ye, Wen XuProteintech Group), mouse anti-IL-17 (1:50; sc-374218, Santa Cruz Biotechnology), and mouse anti-Foxp3 (1:50; sc-53876, Santa Cruz Biotechnology). After washing with PBS, sections were incubated for 1 h at room temperature

(2) The prognostic significance of the IASLC grading system in ALK-positive invasive non-mucinous adenocarcinoma of the lung: correlation with clinicopathological featuresJ Pathol Clin ResMay 12, 2026Dongmei Gu, Jie Bao, Hong Chen, Siyi Chen, Chenxi Shi, Xia Guo, Xiaoyu Zhou, Zhe Lei, Lingchuan Guo, Qianqian YangCarpinteria, CA, USA), CD8 (ZA‐0508, 1:100, Zhongshan Golden Bridge Biotechnology, Beijing, China), and FoxP3 (sc‐53876, 1:100, Santa Cruz, Dallas, TX, USA). Immunohistochemical assessment Any intensity of cytoplasmic

(3) Spatially resolved whole-transcriptomic profiling of EGFR-mutated lung adenocarcinomas stratified by PD-L1 expressionCell Oncol (Dordr)December 22, 2025Chenxi Yu, Chenxi Shi, Hao Zhou, Na Li, Ruyi Ma, SongBai Liu, Zaixiang Tang, Xianling Zhang, Zhe Lei, Hualong Qinfollowing previously described protocols [22, 25]. The primary antibodies used were as follows: anti-FoxP3 (sc-53876, 1:500 dilution, Santa Cruz, USA), anti-CD276 (ab227670, 1:100 dilution, Abcam, USA), and anti-HAVCR2

(4) VISTA+ follicular regulatory T cells modulate the function of effector immune cells: implications for ovarian cancer immune escapeFrontiers in ImmunologyNovember 28, 2025Yan Ma, Yidan Xu, Chunxia Yu, Huatuo Wu, Li Li15070-063), CD3 monoclonal antibody (MultiSciences, F1100300, 0.5 μg/mL), CD28 antibody (Santa Cruz, sc-53876, 0.5 μg/mL), recombinant interleukin-2 (IL-2) protein (proteintech, HZ-1015, 5 ng/mL), recombinant TGF-β1

(5) Host–parasite interaction in latent cerebral toxoplasmosis: The role of cytokine response in a mouse modelOpen Vet JAugust 31, 2025Tuğçe Anteplioğlu, Merve Bişkin Türkmen, Erva Eser, Damla Okatan, Oğuz Kulsc-7219,"Mouse, rat, and human",1:200 CD8,"Santa Cruz; sc-18913, 18913",Mouse,1:200 FOXp3,Santa Cruz; sc-53876,Mouse,1:200 CD19,Abcam; ab25232,Mouse,1:200 Anti-T. gondii,Hazıroğlu et al. (2003),,1:300 Primary

(6) Host–parasite interaction in latent cerebral toxoplasmosis: The role of cytokine response in a mouse modelOpen Veterinary JournalAugust 31, 2025Tuğçe Anteplioğlu, Merve Bişkin Türkmen, Erva Eser, Damla Okatan, Oğuz Kulsc-7219,"Mouse, rat, and human",1:200 CD8,"Santa Cruz; sc-18913, 18913",Mouse,1:200 FOXp3,Santa Cruz; sc-53876,Mouse,1:200 CD19,Abcam; ab25232,Mouse,1:200 Anti-T. gondii,Hazıroğlu et al. (2003),,1:300 Primary

(7) Mesenchymal stromal cells restrain the Th17 cell response via L-amino-acid oxidase within lymph nodesCell Death & DiseaseSeptember 2, 2024Qi Ni, Le Zhen, Zhu Zeng, Jingwen Yang, Yukai Wang, Huanke Xu, Qixiang Zhang, Yongcheng Zhu, Yu Tao, Jing Wang, et al.anti- RORγt (Abcam, ab207082; diluted 1:200) and mouse anti-Foxp3 antibody (Santa Cruz, Dallas, Tx, sc-53876; diluted 1:50), and rabbit anti-LAAO antibody (Abcam, ab222102; diluted 1:100). To reveal primary antibodies,

(8) Identification of key immune cells infiltrated in lung adenocarcinoma microenvironment and their related long noncoding RNAiScienceMarch 15, 2024Kai Wang, Tao Yan, Deyu Guo, Shijie Sun, Yong Liu, Qiang Liu, Guanghui Wang, Jingyu Chen, Jiajun Duretrieval, the paraffin sections were incubated with an anti-Foxp3 antibody (Santa Cruz, catalog number# sc-53876, USA) and then stained with an Alexa Fluor 594-conjugated secondary fluorescent secondary antibody (#8889S,

(9) Tracing immune cells around biomaterials with spatial anchors during large-scale wound regenerationNature communicationsSeptember 26, 2023Yang Y, Chu C, Liu L, Wang C, Hu C, Rung S, Man Y, Qu Y.immunofluorescent staining for F4/80 (29414-1-AP, Proteintech, 1:200), CD206 (360017, Zenbio, 1:100), FOXP3 (sc-53876, Santa Cruz Biotechnology, 1:100), were performed. Flow cytometry analysis Single cells digested from

(10) PD-1, PD-L1 and cAMP immunohistochemical expressions are associated with worse oncological outcome in patients with bladder cancerJournal of cancer research and clinical oncologyJuly 1, 2023Russo GI, Musso N, Lo Giudice A, Asmundo MG, Di Mauro M, Bonacci PG, Massimino M, Bivona D, Stefani S, Pricoco E, et al.

(11) Protective Effect of Novel Lactobacillus plantarum KC3 Isolated from Fermented Kimchi on Gut and Respiratory DisordersMicroorganismsApril 7, 2023Park MS, Kim YJ, Shin HJ, Kwon YJ, Chu J, Lee I, Kim KH, Kim BK, Kim SH, Seo HW, et al.

(12) YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in MiceInternational journal of molecular sciencesFebruary 20, 2023Huang P, Liu M, Zhang J, Zhong X, Zhong C.Number,Country,Dilution BAX,Proteintech,60267-1-Ig,CN,"1/20,000" Bcl2,Proteintech,26593-1-AP,CN,1/3000 Caspase-3,CST,9662s,USA,1/1000 Cleaved caspase-3,CST,9661s,USA,1/1000 FOXP3,Santa Cruz,sc-53876,USA,1/500 CD68,Abcam,ab283654,UK,1/1000 Claudin 5,Abcam,ab131259,UK,1/1000 Aquaporin 4,Abcam,ab128906,UK,1/1000 GAPDH,Proteintech,10494-1-AP,CN,"1/20,000" β-tubulin,Abcam,ab131205,UK,1/5000 Antibody

(13) Primary head and neck cancer cell cultures are susceptible to proliferation of Epstein-Barr virus infected lymphocytesBMC cancerJanuary 13, 2023Shao S, Scholtz LU, Gendreizig S, Martínez-Ruiz L, Florido J, Escames G, Schürmann M, Hain C, Hose L, Mentz A, et al.

(14) Bifidobacterium longum Administration Diminishes Parasitemia and Inflammation During Plasmodium berghei Infection in MiceJournal of inflammation researchJanuary 1, 2023Fitri LE, Sardjono TW, Winaris N, Pawestri AR, Endharti AT, Norahmawati E, Handayani D, Kurniawan SN, Azizah S, Alifia LI, et al.or fluorescein isothiocyanate (FITC) conjugated FoxP3 (Santa Cruz Biotechnology, Inc., cat. number sc-53876, Heidelberg, Germany). The next day, after washing, the slides were stained with 4’,6’-diamidino-2-phenylindole

(15) Supplemental wheat germ modulates phosphorylation of STAT3 in the gut and NF-κBp65 in the adipose tissue of mice fed a Western dietCurrent developments in nutritionJanuary 1, 2023Ojo BA, Alake SE, Kaur A, Wong SY, Keirns B, Ritchey JW, Chowanadisai W, Lin D, Clarke S, Smith BJ, et al.(#Ab7970, Abcam), pNF-κBp65 Ser536 (#sc-136548, Santa Cruz Biotechnology), FOXP3 (Santa Cruz Biotechnology #sc-53876), and GAPDH (#60004-1, Proteinech). Blots were then washed twice with PBS and incubated with an anti-rabbit

(16) Rnf20 inhibition enhances immunotherapy by improving regulatory T cell generationCellular and molecular life sciences : CMLSNovember 13, 2022Luo X, Mo L, Wang X, Zhang S, Liu H, Wu G, Huang Q, Liu D, Yang P.

(17) Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell responseInternational immunopharmacologyNovember 1, 2022Jiao WE, Xu S, Qiao YL, Kong YG, Sun L, Deng YQ, Yang R, Tao ZZ, Hua QQ, Chen SM.

(18) In situ artificial contact sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein-tethering activitiesThe Journal of biological chemistryMay 1, 2022Milanini J, Magdeleine M, Fuggetta N, Ikhlef S, Brau F, Abelanet S, Alpy F, Tomasetto C, Drin G.

(19) CD38(+) B cells affect immunotherapy for allergic rhinitisThe Journal of allergy and clinical immunologyMay 1, 2022Tian GX, Peng KP, Liu MH, Tian DF, Xie HQ, Wang LW, Guo YY, Zhou S, Mo LH, Yang PC.

(20) Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in CholangiocarcinomaMolecular cancer research : MCRMarch 1, 2022Zhang J, Chen W, Ma W, Song K, Lee S, Han C, Wu T.Cell Signaling Technology), anti-TFIID (sc-421), anti-c-Ets1 (sc-55581), anti-pSTAT4 (sc-28296), anti-Foxp3 (sc-53876), anti-HNF1A (sc-393925), anti-HNF3a (sc-101058) (from Santa Cruz Biotechnology). Isotype normal IgG

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FOXP3 (2A11G9) Antibody

FOXP3 (2A11G9) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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FOXP3 (2A11G9) Antibody from Santa Cruz Biotechnology, Inc.

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