Fig 1: Effects of different charges of modified electroconvulsive seizure on the expression levels of PKA, GluR1 and the phosphorylated forms of GluR1 in the hippocampus. (A) Western blot analyses were conducted to examine the expression levels of PKAβ and PKR2 in hippocampal tissue. (B) Western blot analyses were conducted to examine the expression levels of pGluR1 (Ser845), pGluR1 (Ser831) and GluR1 in hippocampal tissue. (C) Quantification of PKAβ and PKR2 expression relative to GAPDH. (D) Quantification of pGluR1 (Ser845), pGluR1 (Ser831) and GluR1 expression relative to GAPDH. Data are presented as the mean ± standard deviation (biochemical assay, n=8 in each group). ##P<0.01 vs. group D and **P<0.01 vs. group M120. GluR1, glutamate receptor 1; p, phosphorylated; PKA, protein kinase A; PKR2, PKA regulatory subunit; PKAβ, PKA catalytic subunit.