Integrin β3 (B-7) Antibody sc-46655 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIntegrin β3 (B-7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-46655
Quantity200 µg/ml
ApplicationsWB, IP, IF, ELISA
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
FormatPurified
Antibody TypePrimary Antibodies
CloneB-7
Hostmouse
TargetIntegrin beta3
IsotypeIgG1
NCBI Gene AliasesGT, CD61, GP3A, BDPLT24, BDPLT2, GPIIIa, BDPLT16, INGRB3, GT2
ClonalityMonoclonal
NCBI Full Gene Nameintegrin subunit beta 3, integrin beta 3

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow nicheEuropean Journal of HistochemistryDecember 16, 2025Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello(pH=6) at 98°C for 30 min. The samples were stained with anti-CD61, 1:100 titre, ((B-7) mouse to mouse, sc-46655; Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA) conjugated with Alexa 488, and MYLK4, 1:100 titre,

(2) GABA-independent activation of GABAB receptor by mechanical forcesNature CommunicationsNovember 7, 2025Yujia Huo, Yiwei Zhou, Li Lin, Fan Yang, Jiyong Meng, Feiteng He, Fengfan Zhang, Mengdan Song, Cangsong Shen, Yuxuan Liu, et al.antibody (#BS2717, 1:1000) was obtained from Bioworld Technology (Shanghai, China). Integrin β3 antibody (#sc-46655, 1:100) and anti-mouse IgG (#sc-2025, 1:500) for the co-immunoprecipitation experiment were purchased

(3) Extracellular matrix protein signaling promotes multi-step cancer vasculogenic mimicry formationCell Commun SignalOctober 8, 2025Gabriel Mingo, Andrés Valdivia, Gema Nicolle Santander, Nicole Babbitt, Varina Aldana, Javiera Pradenas, Pamela González, Cristóbal Canales, Jorge A. Toledo, Carolina Ibáñez, et al.primary antibodies Integrin β1 (P5D2, sc-13590), Cortactin (H-5, sc-55579) and Integrin β3 (2C9.G2, sc-46655) were purchased from Santa Cruz Biotechnology (Dallas, TX). Primary antibody beta-actin and pan-Laminin

(4) Circulating Exosomal Proteins as New Diagnostic Biomarkers for Colorectal Cancer (EXOSCOL01): A Pilot Case–Controlled Study Focusing on MMP14 PotentialJournal of Clinical Laboratory AnalysisApril 17, 2025Mickaël Barhoum, Sylvie Brassart‐Pasco, Aurélie Dupont‐Deshorgue, Aurore Thierry, Lukshe Kanagaratnam, Bertrand Brassart, Fidy Ramaholimihaso, Damien Botsen, Claire Carlier, Mathias Brugel, et al.Antibodies used were: Cell Signaling CS34971S for β1‐integrin, Abcam AB38971 for MMP14, Santa Cruz SC46655, and SC8783 for β3‐integrin and 1(I) collagen, respectively. The membrane undergoes a series of washes

(5) Overcoming Vemurafenib Resistance in Metastatic Melanoma: Targeting Integrins to Improve Treatment EfficacyInternational Journal of Molecular SciencesJuly 20, 2024Asiye Busra Boz Er, Helen M. Sheldrake, Mark Sutherland(MK1): sc-135900, Goat Anti-Rabbit IgG-HRP, Goat Anti-Mouse IgG-HRP, and Mouse monoclonal anti-ITGβ3 (sc-46655) were obtained from Santa Cruz [Santa Cruz, CA, USA]. Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed

(6) Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progressionCell ReportsApril 12, 2024Vinay Ayyappan, Nicole M. Jenkinson, Caitlin M. Tressler, Zheqiong Tan, Menglin Cheng, Xinyi Elaine Shen, Alejandro Guerrero, Kanchan Sonkar, Ruoqing Cai, Oluwatobi Adelaja, et al.(Abcam, Cat# ab129002, RRID:AB_11144129, 1:1000); anti-ITGB3 (CD61) (Santa Cruz Biotechnology, Cat# sc-46655, RRID:AB_627136, 1:100). All uncropped Western blots are shown in Figure S16. CKMT1 immunohistochemistry

(7) Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-IntegrinCellsJanuary 17, 2024Kim EY, Dryer SE.immunoprecipitates were then analyzed by immunoblot using an antibody against β3-integrin (Santa Cruz Biotechnology, sc-46655). In another set of experiments, podocyte lysates were precipitated using an antibody against BAR1 (Santa Cruz, Biotechnology

(8) Preclinical evaluation of oncolytic potential human rotavirus Wt 1-5 in gastric adenocarcinomaPloS oneJanuary 1, 2023Sossa-Rojas H, Franco-Maz PG, Zapata-Acevedo C, Gutierrez-Castañeda LD, Guerrero C.Hsc70 (sc-7298), Hsp60 (sc-59567), Hsp40 (sc-7298), PDI (sc-376369), ERp-57 (sc-166680), integrin β3 (sc-46655), integrin β2 (sc-8420), integrin β1 (sc-374429), and monoclonal rabbit anti-human Bcl-2 (SC-783) were

(9) Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signalingJournal of biomedical scienceDecember 22, 2022Lin SC, Liao YC, Chen PM, Yang YY, Wang YH, Tung SL, Chuang CM, Sung YW, Jang TH, Chuang SE, et al.then added blocking solution to samples for 30 min at 37 °C. Primary antibodies anti-POSTN antibody (SC-46655, Santa Cruz Biotechnology, Dallas, TX, USA), anti-integrin β3 antibody (#13166, Cell Signaling Technology,

(10) Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer TherapyBioconjugate chemistryDecember 21, 2022Dragulska SA, Poursharifi M, Chen Y, Wlodarczyk MT, Acosta Santiago M, Dottino P, Martignetti JA, Mieszawska AJ.Scientific). The blots were proved by primary alphaV (Santa Cruz, #sc-376156) and β3 (Santa Cruz, #sc-46655) antibodies and horseradish peroxidase conjugated secondary antibodies (ThermosFisher Scientific, #31430),

(11) Serum bridging molecules drive candidal invasion of human but not mouse endothelial cellsPLoS pathogensJuly 1, 2022Phan QT, Solis NV, Lin J, Swidergall M, Singh S, Liu H, Sheppard DC, Ibrahim AS, Mitchell AP, Filler SG.Biotechnology, clone H-2, Cat # sc-376156), integrin β3 (Santa Cruz Biotechnology, clone B-7, Cat. # sc-46655), integrin β5 (Santa Cruz Biotechnology, clone F-5, Cat. # sc-398214), or actin (Millipore-Sigma, clone

(12) CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancersMolecular oncologyJuly 1, 2021Bartolomé RA, Robles J, Martin-Regalado Á, Pintado-Berninches L, Burdiel M, Jaén M, Aizpurúa C, Imbaud JI, Casal JI.

(13) Conditional knockdown of integrin beta-3 reveals its involvement in osteolytic and soft tissue lesions of breast cancer skeletal metastasisJournal of cancer research and clinical oncologyFebruary 1, 2021Kovacheva M, Zepp M, Berger S, Berger MR.described before (Kovacheva et al. 2014). Specific antibodies detected the following proteins: integrin β3 (sc-46655) and β-actin (sc1615) (Santa Cruz, Heidelberg, Germany). Beta-actin served as internal loading control.

(14) Berberine and Its Main Metabolite Berberrubine Inhibit Platelet Activation Through Suppressing the Class I PI3Kβ/Rasa3/Rap1 PathwayFrontiers in pharmacologyJanuary 1, 2021Wang C, Cheng Y, Zhang Y, Jin H, Zuo Z, Wang A, Huang J, Jiang J, Kong W.United States). Mouse anti-Rasa3 monoclonal antibody (#SC-398283) and integrin β3 antibody (B-7) (#SC-46655) were sourced from Santa Cruz Biotechnology, Inc. (Dallas, TX, United States). ADP-Glo lipid kinase

(15) Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancerJournal of hematology & oncologyDecember 7, 2020Fu Y, Zhang Y, Lei Z, Liu T, Cai T, Wang A, Du W, Zeng Y, Zhu J, Liu Z, et al.

(16) Chlorpyrifos effects on integrin alpha v and beta 3 in implantation window phaseEnvironmental science and pollution research internationalAugust 1, 2020Gheibi P, Eftekhari Z, Doroud D, Parivar K.

(17) Thy-1 depletion and integrin β3 upregulation-mediated PI3K-Akt-mTOR pathway activation inhibits lung fibroblast autophagy in lipopolysaccharide-induced pulmonary fibrosisLaboratory investigation; a journal of technical methods and pathologyNovember 1, 2019Wan H, Xie T, Xu Q, Hu X, Xing S, Yang H, Gao Y, He Z.antibodies used in this study were: rabbit anti-Thy-1 (ab225, Abcam, USA), mouse anti- integrin β3 (sc-46655, Santa Cruz, USA), rabbit anti-LC3 I/II (L7453, Sigma, USA), rabbit anti-p62/SQSTM1 (#5114, Cell Signaling Technology

(18) Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular ArrestCell reportsSeptember 3, 2019Osmani N, Follain G, García León MJ, Lefebvre O, Busnelli I, Larnicol A, Harlepp S, Goetz JG.

(19) GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrinMolecular biology of the cellMarch 15, 2019Ahat E, Xiang Y, Zhang X, Bekier ME 2nd, Wang Y.(Santa Cruz, cat. no. SC-376156), β1 integrin (DSHB, cat. no. P5D2), β3 integrin (Santa Cruz, cat. no. SC-46655), β5 integrin (Santa Cruz, cat. no. SC-398214), TfR (Invitrogen, cat. no. 13-6800), and α-tubulin (DSHB,

(20) Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α_Ⅴβ₃ integrin/FAK/PI3K/Akt signaling activationOncoTargets and therapyJanuary 1, 2019Chen Y, Chen L, Zhang JY, Chen ZY, Liu TT, Zhang YY, Fu LY, Fan SQ, Zhang MQ, Gan SQ, et al.obtained from Cell Signaling Technology (Beverly, MA, USA). The primary antibodies against integrin β3 (#sc-46655 1:1000) and FAK (#sc-557, 1:1000) were purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA,

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Integrin β3 (B-7) Antibody

Integrin β3 (B-7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Integrin β3 (B-7) Antibody from Santa Cruz Biotechnology, Inc.

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