Polycystin-2 (YCE2) Antibody from Santa Cruz Biotechnology, Inc.

The Polycystin-2 (YCE2) antibody is reactive with mouse, human, and rat species. It has been utilized in various studies, including those investigating the role of polycystins in autosomal dominant polycystic kidney disease and their function in mechanosensing in endothelial cells, as seen in the research by Ha et al. (2020) and Mackay et al. (2020).

Yes, the Polycystin-2 antibody has been shown to work in immunofluorescence applications. For instance, in the study by Mackay et al. (2022), the antibody was used to demonstrate the co-localization of polycystin-1 and polycystin-2 in endothelial cells, which is crucial for understanding their role in flow-mediated vasodilation.

Yes, the Polycystin-2 antibody has been effectively used in Western blotting, as referenced in multiple studies, including those by Xiao et al. (2017) and Mackay et al. (2022). These studies highlight its utility in detecting polycystin-2 in various experimental contexts, contributing to the understanding of its physiological roles.

The Polycystin-2 antibody has been cited in applications such as Western blotting, immunofluorescence, immunohistochemistry, and immunoprecipitation. Its use in studies like those by Carrisoza-Gaytán et al. (2017) and Lea et al. (2020) has provided insights into the polycystin complex's role in kidney function and disease, suggesting potential therapeutic targets for conditions like autosomal dominant polycystic kidney disease.