Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody NB110-40585 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemLysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody
CompanyNovus Biologicals, a Bio-Techne Brand
Price $459.00Supplier Page View Company Product Page
Catalog NumberNB110-40585
ImmunogenThe immunogen recognized by this antibody maps to a region between residue 1010 and the C-terminus (residue 1064) of human Jumonji Domain Containing 2A using the numbering given in entry NP_055478.1 (GeneID 9682)
NCBI Gene AliasesJMJD2, JMJD2A, JHDM3A, TDRD14A
Concentration0.2 mg/ml
ApplicationsImmunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence
ReactivityHuman,Mouse
TargetLysine (K)-specific Demethylase 4A/KDM4A/JMJD2A
FormatTBS and 0.1% BSA
HostRabbit
Quantity0.1 ml
Conjugate/TagUnconjugated
NCBI Full Gene Namelysine demethylase 4A
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaEpigenetics
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at 4C. Do not freeze

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathwayNature communicationsSeptember 14, 2016Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, et al.Covance, 1:1,000), anti-Myc (9E10, Sigma, 1:1,000), anti-α-Tubulin (B-5-1-2, Sigma, 1:10,000), anti-KDM4A (NB110-40585, Novus Biologicals, 1:1,000) and (N154/32, NeuroMab, 1:1,000), anti-mTOR (2972, Cell Signaling, 1:1,000)

(2) KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1OncotargetOctober 13, 2015Qiu MT, Fan Q, Zhu Z, Kwan SY, Chen L, Chen JH, Ying ZL, Zhou Y, Gu W, Wang LH, et al.described [7], antibodies against the following proteins were used: KDM4A (Novus, Littleton, CO, USA, NB110–40585), KDM4B (Bethyl Laboratories, Montgomery, TX, USA, A301–478A), KDM4C (Novus, NBP1–49600), KDM4D (Abcam,

(3) Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damageAging cellApril 1, 2015Gibbs-Seymour I, Markiewicz E, Bekker-Jensen S, Mailand N, Hutchison CJ.BioScience; Cambridge, UK), KAP1(S824p) (A300-767; Bethyl, Cambridge BioScience; Cambridge, UK), JMJD2A (NB110-40585; Novus, Cambridge, UK), and goat polyclonal antibody to MCM6 (sc-9843; Santa Cruz, Heidelberg, Germany).

(4) The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cellsJournal of cellular biochemistryJanuary 1, 0001"Kim TD, Shin S, Berry WL, Oh S, Janknecht R."

(5) Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progressionProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Luo W, Chang R, Zhong J, Pandey A, Semenza GL."

(6) SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagyPLoS pathogensJanuary 1, 0001"Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA."TAF4 (sc-136093), Cyclin T1 (sc-10750), CDK9 (sc-8338), RNF20 (ProteinTech, 21625-1-AP), KDM4A (Novus, NB11040585), KDM4B (Novus, NB100-74605), KDM4C (NBP1-49600), KDM4D (NBP1-03357), KDM5A (NB110-40499), KDM5B (NB100-97821),

(7) Activation of androgen receptor by histone demethylases JMJD2A and JMJD2DBiochemical and biophysical research communicationsJanuary 1, 0001"Shin S, Janknecht R."

(8) JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5Cell reportsJanuary 1, 0001"Mallette FA, Richard S."

(9) Alterations of histone modifications by cobalt compoundsCarcinogenesisJanuary 1, 0001"Li Q, Ke Q, Costa M."

(10) RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sitesThe EMBO journalJanuary 1, 0001"Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S."anti-pan-Actin (C4, Millipore; 1:5000), anti-flag (M2, Sigma; 1:4000), anti-GFP (Roche; 1:1000), anti-JMJD2A (NB11040585, Novus Biologicals; 1:1000), anti-JMJD2B (NB100-74605, Novus Biologicals; 1:2000), anti-JMJD2C (NB110-38884,

(11) SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradationMolecular and cellular biologyJanuary 1, 0001"Tan MK, Lim HJ, Harper JW."

(12) JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cellsExperimental cell researchJanuary 1, 0001"Das A, Chai JC, Jung KH, Das ND, Kang SC, Lee YS, Seo H, Chai YG."

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Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (12)

Reviews

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody from Novus Biologicals, a Bio-Techne Brand

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