Anti-5-HT2A receptor antibody GTX37799 from GeneTex

Product Specs
ItemAnti-5-HT2A receptor antibody
CompanyGeneTex
Price $419.00Supplier Page
Catalog NumberGTX37799
ApplicationsWB, IHC-P, IHC-Fr, FCM
ReactivityHuman, Mouse, Rat
ClonalityPolyclonal
Target5-HT2A receptor
IsotypeIgG
HostRabbit
Quantity100 µg
Concentration0.5mg/ml
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
NCBI Gene Aliases5-hydroxytryptamine receptor 2A, 5-HT2A, HTR2, HTR2, 5-HT2A
Format10mM TBS, 0.5% BSA, 25% Glycerol, 0.015% ProClin 300
NCBI Full Gene Name5-hydroxytryptamine receptor 2A
PurityProtein A purified
ImmunogenKLH conjugated synthetic peptide derived from human 5HT2A Receptor (65-160/471AA)
Research AreaCell Biology, Neuroscience
Gene NameHTR2A
Molecular Weight53

Questions and Answers

Can this antibody be used in studies related to nonalcoholic fatty liver disease?

Yes, the Anti-5-HT2A receptor antibody has been utilized in research investigating the role of serotonin and the HTR2A receptor in nonalcoholic fatty liver disease (NAFLD). A study demonstrated that modulation of the hepatic-gut neural axis involving HTR2A is significant in the etiology of diet-induced NAFLD, suggesting potential therapeutic strategies involving HTR2A antagonists ().

What species does this antibody recognize, and is it effective in different experimental models?

The Anti-5-HT2A receptor antibody recognizes human, mouse, and rat proteins. It has been shown to work effectively in various applications, including immunohistochemistry, as evidenced by its use in histological analyses of mouse models in scientific literature ().

What applications has this antibody been validated for in research?

The Anti-5-HT2A receptor antibody has been validated for use in Western blotting, immunohistochemistry (both paraffin-embedded and frozen sections), and flow cytometry. These applications allow for versatile use in studying the expression and function of the 5-HT2A receptor in various biological contexts.

How was the antibody utilized in the referenced study on NAFLD?

In the study, the Anti-5-HT2A receptor antibody was employed at a dilution of 1:100 for immunohistochemical staining to assess the expression of HTR2A in liver tissues of animal models. This approach facilitated the investigation of the receptor's role in lipid metabolism and the progression of NAFLD ().

GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2ADisease models & mechanismsJuly 1, 2022Owaki T, Kamimura K, Ko M, Nagayama I, Nagoya T, Shibata O, Oda C, Morita S, Kimura A, Sato T, et al.and DAB chromogen tablets (Muto Pure Chemicals, Tokyo, Japan); rabbit polyclonal anti-HTR2A antibody (GTX37799, GeneTex, LA, USA) at 1:100 dilution; rabbit polyclonal anti-HTR2B antibody (GTX32984, GeneTex) at 1:100

(2) Antidepressant-like effects of ginseng fruit saponin in myocardial infarction miceBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJuly 1, 2019Liu M, Liu J, Zhang L, Geng Q, Ge Y.

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Anti-5-HT2A receptor antibody

Anti-5-HT2A receptor antibody

Anti-5-HT2A receptor antibody

Anti-5-HT2A receptor antibody

Anti-5-HT2A receptor antibody from GeneTex

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Questions and Answers

GeneTex

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Anti-5-HT2A receptor antibody from GeneTex

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