Fig 1: The identification of exosomes and uptake of exosomes by RKO/P cells. a. Representative images of exosomes derived from RKO/P and RKO/R taken by TEM (scale bar, 100 nm). b. Exosomal markers (CD63, CD9, ALIX, TSG101) and non-exosomal makers (LaminB1, TBP) were analyzed by WB in Exo/P, Exo/R, RKO/P and RKO/R. c. Histogram indicated diameter of exosomes purified from RKO/P and RKO/R analyzed by HSFCM. d. Confocal images of cells incubated with (+) or without (-) PKH-26 labelled Exo/P and Exo/R for 6 h. (scale bar, 10 µm)