FABP7/B-FABP Antibody AF3166 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFABP7/B-FABP Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF3166
NCBI Gene AliasesBLBP, FABPB, MRG, B-FABP
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry
Conjugate/TagUnconjugated
HostGoat
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetFABP7/B-FABP
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse,Primate - Macaca fuscata (Japanese Macaque)
NCBI Full Gene Namefatty acid binding protein 7
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human FABP7/B-FABP, Met1-Ala132, Accession # O15540
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human FABP7/B-FABP in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) FABP1, rhFABP2, rhFABP3, rhFABP4, rhFABP5, rhFABP6, rhFABP8, rhFABP9 and recombinant mouse FABP9 is observed.

Sizes Available: 100 ug (also 25 ug)

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Questions and Answers

Can this antibody be used to study glioblastoma and its metabolic characteristics?

Yes, the FABP7/B-FABP antibody has been shown to play a significant role in glioblastoma research. In a study, inhibition of FABP7 was found to sensitize slow-cycling cells in glioblastoma to metabolic stress, suggesting that targeting FABP7-related metabolic pathways could be a viable therapeutic strategy for this type of cancer .

Is the FABP7/B-FABP antibody effective for immunohistochemistry in human tissues?

The FABP7/B-FABP antibody has been successfully utilized in immunohistochemistry to analyze its expression in various human tissues, including adenoid cystic carcinoma of the salivary glands, where it was correlated with poor prognosis . Additionally, it has been used in studies involving dorsal root ganglia, demonstrating its applicability in human tissue analysis .

What are the implications of using this antibody in studies related to neuropathic pain?

The FABP7/B-FABP antibody has been referenced in studies investigating the role of macrophages and microglia in neuropathic pain. It was used to assess FABP7 expression in the context of inflammatory responses following peripheral nerve injury, indicating its relevance in understanding the molecular mechanisms underlying neuropathic pain .

How specific is the FABP7/B-FABP antibody in detecting its target?

The FABP7/B-FABP antibody has demonstrated high specificity, with less than 5% cross-reactivity with other fatty acid-binding proteins in direct ELISAs and Western blots. This specificity is crucial for accurately studying the role of FABP7 in various biological contexts .

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor populationBrain : a journal of neurologyDecember 4, 2025Benoit CR, Sattler LB, Aylward AJ, Pembridge O, Kim B, Muratore CR, Liao M, He A, Ashour N, Fancher SB, et al.(Novus Biologicals, Cat. No. MAB1259, 1:500), VIM (R&D Systems, Cat. No. MAB2105, 1:100), BLBP (R&D Systems, Cat. No. AF3166, 1:100). Secondary antibodies (1:2000 dilution) were applied for 1 h, followed by 4',6-diamidino-2-phenylindole

(2) PROX1 is necessary for cellular patterning, innervation and differentiation in the mouse organ of CortiDevelopmental BiologyOctober 1, 2025Shubham Kale, Dimitri Traenkner, Ellison J. Goodrich, Satish R. Ghimire, Thomas M. Coate, Michael R. Deansthis study were: Rat anti-CD44 (1:1000, PFA, DSHB 5D2–27), Goat anti-FABP7 (1:1000, PFA, R&D Systems AF3166), Rat anti-Ki-67 (1:1000, PFA, Invitrogen 740008T), Rabbit anti-NFH (1:1000, PFA, Millipore AB1989),

(3) Single nucleus multiomic atlas of human dorsal root ganglia reveals the contribution of non-neuronal cell types to painbioRxiv : the preprint server for biologySeptember 22, 2025Zhao G, Boyer K, Meriau P, Yang L, Naz H, Rosen S, Murray G, Dourson A, Mwirigi J, Del Rosario J, et al.

(4) Macrophage/microglia-producing transient increase of platelet-activating factor is involved in neuropathic painiScienceApril 19, 2024Yamamoto S, Hashidate-Yoshida T, Yoshinari Y, Shimizu T, Shindou H.PA5-52481, 1:1000−1:2000), mouse anti-β3 tubulin (Biolegend, 801202, 1:2000), goat anti-FABP7 (R&D systems, AF3166, 1:1000), goat anti-SOX10 (R&D systems, AF2864, 1:1000), mouse anti-NeuN (Abcam, ab104224, 1:1000),

(5) DRGquant: A new modular AI-based pipeline for 3D analysis of the DRGJournal of neuroscience methodsApril 1, 2022Hunt MA, Lund H, Delay L, Dos Santos GG, Pham A, Kurtovic Z, Telang A, Lee A, Parvathaneni A, Kussick E, et al.1:50), NeuN (Milipore MAB377B, 1:300), mCherry (Rockland 600–401–379, 1:1000), (Fabp7 R&D Systems, AF3166, 1:500) and DAPI (1:10,000), was as follows: All washing steps were done in 12 well plates with transfer

(6) A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse modelsEBioMedicineOctober 1, 2021Cheng A, Jia W, Kawahata I, Fukunaga K.2314110 Iba-1,Fujifilm,016-20001,1:1000,AB_839506 4-HNE,JalCA,MHN-100P,1:1000,AB_1106813 TNF-α,Abcam,ab92324,1:500,AB_10561788 IL-1β,Abcam,ab9722,1:1000,AB_308765 MBP,Abcam,ab7349,1:500,AB_305869 FABP5,R&D Systems,AF3077,1:200,AB_2100340 FABP7,R&D Systems,AF3166,1:200,AB_2100475 VDAC-1,CST,4866,1:500,AB_2272627This is not a pattern of 'rridsoftware' external object

(7) Discrepancy in the Usage of GFAP as a Marker of Satellite Glial Cell ReactivityBiomedicinesAugust 16, 2021Mohr KM, Pallesen LT, Richner M, Vaegter CB.Cat.",RRID,Dilution Rabbit anti-GFAP,"Dako/Agilent, Z0334",AB_10013382,1:500 Goat anti-Fabp7,"R&D Systems, AF3166",AB_2100475,1:350 Mouse anti-neuronal Class III β-tubulin,"BioLegend, MMS-435P",AB_2313773,1:1000 "Donkey

(8) Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in MiceBiomedicinesMay 10, 2021Guo Q, Kawahata I, Degawa T, Ikeda-Matsuo Y, Sun M, Han F, Fukunaga K.anti-FABP5 (1:1000; R&D Systems, AF3077, Minneapolis, MN, USA), goat anti-FABP7 (1:1000; R&D Systems, AF3166, Minneapolis, MN, USA), rabbit anti-mPGES-1 2.3. Drug Treatment (1:200; Cayman Chemical, 160140, Ann

(9) Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in OligodendrocytesBiomedicinesDecember 20, 2020Cheng A, Kawahata I, Fukunaga K.

(10) Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point MutationCell reportsApril 21, 2020Zhang K, Yu F, Zhu J, Han S, Chen J, Wu X, Chen Y, Shen T, Liao J, Guo W, et al.

(11) Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastomaThe EMBO journalDecember 3, 2018Hoang-Minh LB, Siebzehnrubl FA, Yang C, Suzuki-Hatano S, Dajac K, Loche T, Andrews N, Schmoll Massari M, Patel J, Amin K, et al.MitoProbe DiIC1(5) (Molecular Probes), FABP7 (Santa Cruz Biotechnology, #sc-30088), FABP7 (R&D Systems, #AF3166), human Nestin (Millipore, #MAB5326), Ncadherin (Millipore, #04-1126), beta-catenin (Sigma, #C2206),

(12) Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 DegradationThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 31, 2018Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, et al.

(13) Functional analysis of fatty acid binding protein 7 and its effect on fatty acid of renal cell carcinoma cell linesBMC cancerMarch 14, 2017Takaoka N, Takayama T, Ozono S.Buckinghamshire HP7 9NA, England), and the membrane was incubated with 1 g/L of an FABP7 antibody (AF3166; R&D Systems, Minneapolis, MN, USA) diluted 1:5000. Antibody-antigen complexes were visualized using

(14) Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significanceTranslational oncologyDecember 1, 2014Phuchareon J, Overdevest JB, McCormick F, Eisele DW, van Zante A, Tetsu O.significant. Immunohistochemistry Immunohistochemistry was performed on unstained sections using antibody-based staining kits for FABP7 (AF3166; R&D Systems, Minneapolis, MN) or goat isotype control (AB-108-C; R&D Systems) at the UCSF Comprehensive

(15) Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell linesBMC molecular biologyJuly 19, 2011Takaoka N, Takayama T, Teratani T, Sugiyama T, Mugiya S, Ozono S.[7], Jung et al. [39] and Faus et al. [40], respectively. Antibodies An anti-human FABP7 Antibody (AF3166) was purchased from R&D Systems, Inc. Peroxidase-conjugated donkey anti-goat IgG (86285) was purchased

(16) Expression of fatty acid-binding proteins in adult hippocampal neurogenic niche of postischemic monkeysHippocampusFebruary 1, 2011Boneva NB, Kaplamadzhiev DB, Sahara S, Kikuchi H, Pyko IV, Kikuchi M, Tonchev AB, Yamashima T.

(17) Tiered Sympathetic Control of Cardiac Function Revealed by Viral Tracing and Single Cell Transcriptome ProfilingbioRxiv : the preprint server for biologyJanuary 1, 0001"Sharma S, Littman R, Tompkins J, Arneson D, Contreras J, Dajani AH, Ang K, Tsanhani A, Sun X, Jay PY, et al."

(18) Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profilingeLifeJanuary 1, 0001"Sharma S, Littman R, Tompkins JD, Arneson D, Contreras J, Dajani AH, Ang K, Tsanhani A, Sun X, Jay PY, et al."(Thermo Fisher Scientific, #PA5-76698, 1:25), rat anti-SST (Millipore-Sigma, #MAB354, 1:50), goat anti-FABP7 (R&D system, #AF3166, 1:100), rabbit anti-CASZ1 (Thermo Fisher Scientific, #PA5-55800, 1:100), goat anti-cardiac troponin

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