GLP-1R Antibody

Product Specs
ItemGLP-1R Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNBP1-97308
Conjugate/TagUnconjugated
HostRabbit
FormatPBS
ReactivityCanine,Human,Mouse,Rat
Quantity0.1 ml (also 0.025 ml)
ApplicationsCytometric Bead Assay Standard,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Dot Blot,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
Concentration1.0 mg/ml
TargetGLP-1R
ImmunogenA synthetic peptide made to an internal portion of the human GLP1R protein (between residues 250-350) [UniProt P43220]
NCBI Full Gene Nameglucagon like peptide 1 receptor
ClonalityPolyclonal
NCBI Gene AliasesGLP-1, GLP-1-R, GLP-1R
IsotypeIgG
Antibody TypePrimary Antibodies
Research AreaCancer, GPCR, Lipid and Metabolism, Signal Transduction
PurityImmunogen affinity purified
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

Questions and Answers

What species can I use this GLP-1R antibody on for my experiments?

This GLP-1R antibody has been shown to work with several species, including humans, mice, rats, and canines.

Has this antibody been used in any specific applications in scientific research?

Yes, the GLP-1R antibody has been utilized in various applications, including Western blotting and immunohistochemistry, as evidenced by its use in studies examining GLP-1 receptor expression in mouse models of diabetes and metabolic disorders.

Can this antibody help in studying the role of GLP-1R in metabolic diseases?

Indeed, the GLP-1R antibody has been referenced in studies investigating its role in metabolic processes, such as glucose homeostasis and energy balance, particularly in the context of type 2 diabetes and non-alcoholic fatty liver disease.

Is there any evidence of this antibody being effective in detecting GLP-1R in tissue samples?

Yes, the antibody has been effectively used in immunohistochemical staining of liver tissues, demonstrating its capability to detect GLP-1R expression in various studies, including those focused on liver diseases and metabolic regulation.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathwayJournal of cancer research and clinical oncologyMarch 7, 2025Wang C, Wu Z, Zhou J, Cheng B, Huang Y.Primary antibodies,Company,Cat.No,Dilution GLP-1R,"Novus, USA",NBP1-97308,1:1000 Ki67,"Affinity, China",AF0198,1:1000 PCNA,"Servicebio, China",GB11010-1–100,1:1000 E-cadherin,"Proteintech,

(2) Semaglutide May Alleviate Hepatic Steatosis in T2DM Combined with NFALD Mice via miR-5120/ABHD6Drug design, development and therapyJanuary 1, 2022Li R, Ye Z, She D, Fang P, Zong G, Hu K, Kong D, Xu W, Li L, Zhou Y, et al.Hepa 1–6 cells were fixed with paraformaldehyde and then incubated overnight with GLP-1R antibody (#NBP1-97308, 1:100, Novus Biologicals, Littleton, CO, USA). After cleaning, the cells were further incubated with

(3) Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM MiceCell transplantationJanuary 1, 2020Deng H, Yang F, Ma X, Wang Y, Chen Q, Yuan L.(ab22625 and ab23472; Abcam), mouse anti-GLP1R (sc390773; Santa Cruz, Dallas, TX, USA), rabbit anti-GLP1R (NBP1-97308; Novus, CO, USA), mouse antisomatostatin (sc-74556; Santa Cruz), goat antipancreatic polypeptide (Ab77192;

(4) Effect of hCMSCs and liraglutide combination in ALI through cAMP/PKAc/β-catenin signaling pathwayStem cell research & therapyJanuary 1, 0001"Feng Y, Wang L, Ma X, Yang X, Don O, Chen X, Qu J, Song Y."

(5) "Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-κB Activation"EndocrinologyJanuary 1, 0001"Iwaya C, Nomiyama T, Komatsu S, Kawanami T, Tsutsumi Y, Hamaguchi Y, Horikawa T, Yoshinaga Y, Yamashita S, Tanaka T, et al."

(6) Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathyBrain : a journal of neurologyJanuary 1, 0001"Rocha-Ferreira E, Poupon L, Zelco A, Leverin AL, Nair S, Jonsdotter A, Carlsson Y, Thornton C, Hagberg H, Rahim AA."

(7) Insulinoma induces a hyperinsulinemia-mediated decrease of GLUT2 and GLP1 receptor in normal pancreatic β-cellsBiochemical and biophysical research communicationsJanuary 1, 0001"Sho H, Fukui K, Yoneda S, Toyoda S, Ozawa H, Ishibashi C, Fujita Y, Eguchi H, Kozawa J, Shimomura I."

(8) Functional activity of murine intestinal mucosal cells is regulated by the glucagon-like peptide-1 receptorPeptidesJanuary 1, 0001"Kedees MH, Guz Y, Grigoryan M, Teitelman G."

(9) Exendin-4 inhibits growth and augments apoptosis of ovarian cancer cellsMolecular and cellular endocrinologyJanuary 1, 0001"He W, Yu S, Wang L, He M, Cao X, Li Y, Xiao H."

(10) "Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice"British journal of pharmacologyJanuary 1, 0001"Steven S, Jurk K, Kopp M, Kröller-Schön S, Mikhed Y, Schwierczek K, Roohani S, Kashani F, Oelze M, Klein T, et al."

(11) Exendin-4 does not modify growth or apoptosis of human colon cancer cellsEndocrine researchJanuary 1, 0001"Wenjing H, Shuang Y, Weisong L, Haipeng X."

(12) "GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function"Cell metabolismJanuary 1, 0001"Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, et al."Western Blotting-Reagent, at 4°C overnight. The following primary antibodies and dilutions were used: anti-GLP-1R (1:1000, #NBP1-97308, Novus Biologicals), anti-Akt (#4686, Cell Signaling), anti-p-Akt(S473) (#4060, Cell Signaling), anti-NDUFA9

(13) Liraglutide protects against lethal renal ischemia-reperfusion injury by inhibiting high-mobility group box 1 nuclear-cytoplasmic translocation and releasePharmacological researchJanuary 1, 0001"Li Y, Xu B, Yang J, Wang L, Tan X, Hu X, Sun L, Chen S, Zhu L, Chen X, et al."

(14) Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involvedAmerican journal of physiology. Renal physiologyJanuary 1, 0001"Chaudhari S, Yazdizadeh Shotorbani P, Tao Y, Davis ME, Mallet RT, Ma R."

(15) GLP-1 receptor agonist as treatment for cancer as well as diabetes: beyond blood glucose controlExpert review of endocrinology & metabolismJanuary 1, 0001"Nomiyama T, Yanase T."

(16) Dipeptidyl Peptidase 4 Inhibition Ameliorates Chronic Kidney Disease in a Model of Salt-Dependent HypertensionOxidative medicine and cellular longevityJanuary 1, 0001"Cappetta D, Ciuffreda LP, Cozzolino A, Esposito G, Scavone C, Sapio L, Naviglio S, D'Amario D, Crea F, Rossi F, et al."

(17) Exendin-4 improves behaviorial deficits via GLP-1/GLP-1R signaling following partial hepatectomyBrain researchJanuary 1, 0001"Zhou Y, Li Z, Cao X, Ma H, White PF, Xu X, Jiang Y, Sun X, Cui Y."

(18) Combined Treatment with Exendin-4 and Metformin Attenuates Prostate Cancer GrowthPloS oneJanuary 1, 0001"Tsutsumi Y, Nomiyama T, Kawanami T, Hamaguchi Y, Terawaki Y, Tanaka T, Murase K, Motonaga R, Tanabe M, Yanase T."was made from the center of one tumor. Paraffin sections were incubated with anti-GLP-1R antibody (NBP1-97308; Novus Biologicals, Littleton, CO, USA), anti-P504S antibody (sc–81710; Santa Cruz Biotechnology Inc.),

(19) Glucagon-Like Peptide 1 Receptor Agonist Improves Renal Tubular Damage in Mice with Diabetic Kidney Disease"Diabetes, metabolic syndrome and obesity : targets and therapy"January 1, 0001"Li R, She D, Ye Z, Fang P, Zong G, Zhao Y, Hu K, Zhang L, Lei S, Zhang K, et al."previously described.28 Kidney sections, ovary sections and mTEC cells were stained with GLP-1R antibody (NBP1-97308, Novus Biologicals, USA) overnight at 4°C, followed by incubation with Alexa-488 goat anti-rabbit (#111-545-003,

(20) "Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis"Scientific reportsJanuary 1, 0001"Meurot C, Martin C, Sudre L, Breton J, Bougault C, Rattenbach R, Bismuth K, Jacques C, Berenbaum F."rabbit polyclonal immunoglobulin G (IgG) anti-GLP-1R antibody was purchased from Novus Biologicals (NBP1-97308, Centennial, Colo., USA). ImmPRESS® horseradish peroxidase (HRP) goat anti-rabbit IgG polymer detection

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GLP-1R Antibody - BSA Free

GLP-1R Antibody - BSA Free

GLP-1R Antibody - BSA Free

GLP-1R Antibody - BSA Free

GLP-1R Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Questions and Answers

Novus Biologicals, a Bio-Techne Brand

Citations (30)

Reviews

GLP-1R Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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