AAA Biotech, LLC's RICTOR Antibody is a Mouse monoclonal antibody. The RICTOR Antibody was generated using RICTOR as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Non-Human Primate. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals. mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GbetaL and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GbetaL, Sin1 and rictor. The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro