TLR4 (HTA125) Antibody sc-13593 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTLR4 (HTA125) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13593
Antibody TypePrimary Antibodies
NCBI Gene AliasesCD284, TOLL, TLR-4, ly-96, ARMD10, MD2, MD-2, ESOP-1
ApplicationsIP, IF, IHC(P), FCM
CloneHTA125
Quantity200 µg/ml
Reactivityhuman
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
NCBI Full Gene Nametoll like receptor 4, lymphocyte antigen 96
TargetTLR4
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) TLR4/MyD88 expression patterns and novel genetic variants: association with aggressive clinicopathological features in colorectal cancerFront OncolJuly 9, 2025Thai Tra Dang, Viet Nhat Pham, Ngoc Dung Tran, Thu Hang Ngo, Van Mao Can, Huy Hoang Nguyen, Thi Xuan Nguyen, Thanh Chung Danganti-MLH1 (M1), anti-MSH2 (G219-1129), anti-MSH6 (SPO3) (all from Leica, Germany), and anti-TLR4 (HTA125: sc-13593) and anti-MyD88 (B-1: sc-136970) (both from Santa Cruz Biotech, Santa Cruz, CA, USA). After deparaffinization

(2) The PYRIN domain is required for TLR4-mediated inflammation by PYHIN family membersiScienceApril 11, 2025Andrea Iannucci, Davide Lacarbonara, Valeria Caneparo, Federica Castiglioni, Andrea Butticè, Stefano Raviola, Chiara Porta, Riccardo Miggiano, Ivan Zanoni, Marisa Gariglio, et al.described in68), mAb anti-human TLR4 (sc-293072, Santa Cruz Biotechnologies), mAb anti-human TLR4 (sc-13593, Santa Cruz Biotechnologies), mAb anti-β-actin (A1978, Sigma-Aldrich), rabbit IgG-HRP (A6154, Sigma-Aldrich),

(3) Phosphate (Pi) Transporter PIT1 Induces Pi Starvation in Salmonella-Containing Vacuole in HeLa CellsInt J Mol SciDecember 7, 2023Wen Yang, Yingxing Feng, Jun Yan, Chenbo Kang, Ting Yao, Hongmin Sun, Zhihui Chengmouse monoclonal to GroEL (Abcam, ab82592), and TLR4 (Santa Cruz Biotechnology, Santa Cruz, CA, USA, sc-13593); Goat Anti-Rabbit IgG H&L-conjugated Alexa Fluor 647 IgG (Abcam, ab150083), Goat Anti-Mouse IgG (BBI,

(4) Interleukin-17A-Correlated Myocarditis in Patients with Psoriasis: Cardiac Recovery following Secukinumab AdministrationJournal of clinical medicineJune 12, 2023Frustaci A, Galea N, Dominici L, Verardo R, Alfarano M, Scialla R, Richetta AG.

(5) P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative StressInternational journal of molecular sciencesJanuary 4, 2023Verma A, Azhar G, Zhang X, Patyal P, Kc G, Sharma S, Che Y, Wei JY.the cells with Anti-TLR4 conjugated Antibody (1:100) Alexa Fluor® 488 (Santa Cruz, Dallas, TX, USA; sc-13593 AF488, HTA125) overnight at 4 °C as per manufacturer’s instructions. Cells were then counterstained

(6) Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microgliaFrontiers in pharmacologyJanuary 1, 2023Wagner A, Pehar M, Yan Z, Kulka M.CD86-allophycocyanin (APC) (558703, BD Biosciences, Franklin Lakes, NJ, United States), mouse anti-human TLR4-FITC (sc-13593, Santa Cruz Biotechnology Inc., Dallax, TX, United States), or mouse anti-human CD45-fluorescein isothiocyanate

(7) Mechanism analysis of octapeptide from microalgae, Isochrysis zhanjiangensis for suppressing vascular injury and angiogenesis in human umbilical vein endothelial cellInternational immunopharmacologyOctober 1, 2022Lin L, He YL, Tang Y, Hong P, Zhou C, Sun S, Qian ZJ.

(8) Extracellular DJ-1 induces sterile inflammation in the ischemic brainPLoS biologyMay 1, 2021Nakamura K, Sakai S, Tsuyama J, Nakamura A, Otani K, Kurabayashi K, Yogiashi Y, Masai H, Shichita T.1:50 dilution, Cat# ab16894) or anti-TLR4 antibody (Santa Cruz Biotechnology, USA, 1:50 dilution, Cat# sc-13593) was used for detecting PLA signals in the myeloid cells detected by anti-CD11b antibody (GeneTex, USA,

(9) Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide bindingPLoS pathogensSeptember 1, 2020Iannucci A, Caneparo V, Raviola S, Debernardi I, Colangelo D, Miggiano R, Griffante G, Landolfo S, Gariglio M, De Andrea M.described in [1], mAb anti-human TLR4 (sc-293072, Santa Cruz Biotechnologies), mAb anti-human TLR4 (sc-13593, Santa Cruz Biotechnologies), mAb anti-human TLR4 (mabg-htlr4, InvivoGen), rabbit polyclonal anti-MD2

(10) Diminution of Phagocytosed Micro/Nanoparticles by Tethering with Immunoregulatory CD200 ProteinScientific reportsMay 25, 2020Zhang J, Peng CA.

(11) TLR4 Stimulation Promotes Human AVIC Fibrogenic Activity through Upregulation of Neurotrophin 3 ProductionInternational journal of molecular sciencesFebruary 14, 2020Yao Q, The E, Ao L, Zhai Y, Osterholt MK, Fullerton DA, Meng X.

(12) Microbiota determines insulin sensitivity in TLR2-KO miceLife sciencesOctober 1, 2019Guadagnini D, Rocha GZ, Santos A, Assalin HB, Hirabara SM, Curi R, Oliveira AG, Prada PO, Saad MJA.

(13) MicroRNA‑451 relieves inflammation in cerebral ischemia‑reperfusion via the Toll‑like receptor 4/MyD88/NF‑κB signaling pathwayMolecular medicine reportsOctober 1, 2019Li W, Dong M, Chu L, Feng L, Sun X.in TBS-Tween-20 (TBST) for 1 h at 37°C and incubated overnight at 4°C with antibodies against TLR4 (sc-13593, 1:500; Santa Cruz Biotechnology, Inc.), MyD88 (sc-74532, 1:500; Santa Cruz Biotechnology, Inc.), NF-κB/p65

(14) miR‑27a suppresses TLR4‑induced renal ischemia‑reperfusion injuryMolecular medicine reportsAugust 1, 2019Wang Y, Wang D, Jin Z.temperature for 10 min, and subsequently incubated with a primary antibody against TLR4 (1:100, cat. no. sc-13593, Santa Cruz Biotechnology, Inc.) 4°C overnight. An avidin-biotin-HRP complex immunodetection kit (Shanghai

(15) Bacterial Clearance Is Enhanced by α2,3- and α2,6-Sialyllactose via Receptor-Mediated Endocytosis and PhagocytosisInfection and immunityJanuary 1, 2019Kim J, Kim YJ, Kim JW.blocked with 1% bovine serum albumin (BSA) for 1 h at room temperature. After incubation with anti-TLR4 (sc-13593; Santa Cruz Biotechnology, Dallas, TX, USA) or anti-Rac1 (03589; EMD Millipore, Darmstadt, Germany)

(16) Expression of TLR4 gene is downregulated in acquired immune deficiency syndrome-associated Kaposi's sarcomaExperimental and therapeutic medicineJanuary 1, 2019Lu X, Wan X, Li X, Pan K, Maimaitiaili W, Zhang Y.binding. After removing the serum, TLR4 mouse anti‑human monoclonal antibody (1:150 dilution; cat. no. sc‑13593; Santa Cruz Biotechnology, Inc.) was added, followed by incubation at 4˚C overnight. The samples were

(17) IVIg Promote Cross-Tolerance against Inflammatory Stimuli In Vitro and In VivoJournal of immunology (Baltimore, Md. : 1950)July 1, 2018Domínguez-Soto Á, Simón-Fuentes M, de Las Casas-Engel M, Cuevas VD, López-Bravo M, Domínguez-Andrés J, Saz-Leal P, Sancho D, Ardavín C, Ochoa-Grullón J, et al.carried out by flow cytometry as described previously (46) using either a mAb specific for human TLR4 (sc-13593; Santa Cruz Biotechnology) or an isotype-matched control Ab (Chemicon) and followed by staining with

(18) TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophagesBMC pulmonary medicineDecember 12, 2017Lv J, He X, Wang H, Wang Z, Kelly GT, Wang X, Chen Y, Wang T, Qian Z.

(19) Homocysteine‑induced oxidative stress through TLR4/NF‑κB/DNMT1‑mediated LOX‑1 DNA methylation in endothelial cellsMolecular medicine reportsDecember 1, 2017Ma SC, Hao YJ, Jiao Y, Wang YH, Xu LB, Mao CY, Yang XL, Yang AN, Tian J, Zhang MH, et al.shaker. The LOX‑1 and TLR‑4 proteins were detected using LOX‑1 (cat. no. sc‑66155) and TLR‑4 (cat. no. sc‑13593) antibodies were obtained from Santa Cruz Biotechnology, Inc., (Dallas, TX, US) diluted 1:500, and β‑actin

(20) Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarctionBiochimica et biophysica acta. Molecular basis of diseaseNovember 1, 2017Di Maggio S, Milano G, De Marchis F, D'Ambrosio A, Bertolotti M, Palacios BS, Badi I, Sommariva E, Pompilio G, Capogrossi MC, et al.

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TLR4 (HTA125) Antibody

TLR4 (HTA125) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TLR4 (HTA125) Antibody from Santa Cruz Biotechnology, Inc.

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