C3a Receptor Polyclonal Antibody from Bioss Inc.

Yes, the C3a Receptor Polyclonal Antibody has been successfully utilized in immunohistochemistry, as demonstrated in studies involving mouse models. For instance, in one study, the antibody was applied at a dilution of 1:200 to analyze the expression of C3AR1 in tissue samples from K7M2-induced osteosarcoma mice (lu2024).

The C3a receptor is implicated in immune cell trafficking within the tumor microenvironment. Research indicates that blocking C3a receptor signaling can enhance the infiltration of natural killer cells into tumors, potentially improving the efficacy of immunotherapy for cancer treatment (nandagop2022).

Yes, the C3a Receptor Polyclonal Antibody has been used in studies examining muscle regeneration. Specifically, it was employed to assess the expression of C3AR1 in the context of muscle trauma and regeneration in obese mice, highlighting its relevance in understanding the molecular mechanisms involved in muscle healing (xu2018).

The C3a Receptor Polyclonal Antibody is reactive with both human and mouse species. Its effectiveness has been validated in various applications, including Western blotting and immunofluorescence, as reported in multiple scientific articles that utilized this antibody for studying C3AR1 expression and function in different biological contexts (lu2024, nandagop2022, xu2018).