The CD146 Polyclonal Antibody, PE Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to MCAM. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The CD146 Polyclonal Antibody, PE Conjugated has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration