Mesothelin (K1) Antibody sc-33672 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMesothelin (K1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-33672
Antibody TypePrimary Antibodies
NCBI Gene AliasesMPF, SMRP
Quantity200 µg/ml
CloneK1
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, FCM
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namemesothelin
TargetMesothelin
IsotypeIgG1

Questions and Answers

Can this antibody be used for immunofluorescence in cancer research?

Yes, the Mesothelin (K1) Antibody has been successfully used for immunofluorescence applications, as demonstrated in studies involving pancreatic cancer cell lines such as JoPaca-1 and BxPC-3, where it was utilized to detect mesothelin expression in cultured cells ().

Is this antibody effective for detecting mesothelin in colorectal cancer tissues?

The Mesothelin (K1) Antibody has been shown to effectively detect mesothelin protein in colorectal cancer tissues through immunohistochemical staining, indicating its utility in studying mesothelin expression in this context ().

What species can this antibody react with?

This antibody is reactive with mouse, human, and rat species, making it versatile for various experimental models in cancer research.

Has this antibody been cited in any significant research studies?

Yes, the Mesothelin (K1) Antibody has been cited in at least 16 scientific articles, indicating its relevance and application in various studies related to cancer biology and mesothelin expression.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Mesothelial cells promote peritoneal invasion and metastasis of ascites-derived ovarian cancer cells through spheroid formationSci AdvFebruary 6, 2026Kaname Uno, Masato Yoshihara, Yoshihiko Yamakita, Kazuhisa Kitami, Shohei Iyoshi, Mai Sugiyama, Yoshihiro Koya, Tomihiro Kanayama, Haruhito Sahara, Satoshi Nomura, et al.1/50), PDGFRα (no. 3146, Cell Signaling, rabbit, 1/50), desmin (no. 5322, CST, rabbit, 1/100), MSLN (SC-33672, Santa Cruz, mouse, 1/50), UPK3B (NBP1-92564, NOVUS, rabbit, 1/500), KRT8 (M0631, DAKO, 1/50), and KRT18

(2) Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer NanovaccinesAdvanced ScienceFebruary 1, 2026Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, et al.extracellular staining of CD3/CD4/CD8 or MSLN, 0.5 µL of each antibody (see Table S1 and Mesothelin K1‐PE, sc‐33672, Santa Cruz Biotech) was added. Cells were then washed twice with FACS buffer and incubated with fixation

(3) Mesothelin as a biomarker and potential therapeutic target in rheumatoid arthritis bone destructionCell Reports MedicineNovember 18, 2025Xiaohui Su, Qian Wang, Jingbo Wang, Panpan Zhu, Wanyi Guo, Jinghang Yang, Siyu Li, Fengyu Huang, Mingzhu Qi, Hui Li, et al.Rabbit mAb,Abcam,Cat# ab187063; RRID:AB_3665045 Anti-MSLN Mouse mAb,Santa Cruz Biotechnology,Cat# sc-33672; RRID:AB_627930 Anti-PI3K p110a(C73F8) Rabbit mAb,Cell Signaling Technology,Cat# 4249S; RRID:AB_2165248 Anti-Phospho Akt (Ser473

(4) Modulation of canonical Wnt signaling regulates peribiliary mesenchymal identity during homeostasis and injuryHepatology communicationsFebruary 1, 2024Singh S, Budiman T, Redmond D, Gupta V.smooth muscle actin (Acta2) (1:200, Abcam, ab5694), mouse anti-Mesothelin (Msln) (1:200, Santa-Cruz, sc-33672), rat monoclonal anti-Pdgfra (1:200, Thermo, 14-1401-82), rat monoclonal anti-Cd31 (1:200, BD Biosciences,

(5) Endogenously produced hyaluronan contributes to the regulation of peritoneal adhesion developmentBioFactors (Oxford, England)July 1, 2023Kocurkova A, Kerberova M, Nesporova K, Lehka K, Sandanusova M, Simek M, Velebny V, Kubala L, Ambrozova G.

(6) A single-cell comparison of adult and fetal human epicardium defines the age-associated changes in epicardial activityNat Cardiovasc ResDecember 21, 2022Knight-Schrijver VR, Davaapil H, Bayraktar S, Ross ADB, Kanemaru K, Cranley J, Dabrowska M, Patel M, Polanski K, He X, et al.this study for immunofluorescent imaging included: UPK3B, PA552696 (Themo Fisher Scientific); MSLN, sc33672 (Santa Cruz Biotechnology); KRT19, sc6278 (Santa Cruz Biotechnology); POSTN, MAB3548 (R&D Systems);

(7) Effects of hsa-mir-145-5p on the Regulation of msln Expression in Colorectal AdenocarcinomaAnalytical Cellular PathologyMarch 15, 2022Junhua Li, Bulin Baila, Tian Xiang Xu, Jiang Song, Su Rina, Ji Wu, Tegexibaiyin Wangsections were further sealed with 2% BSA and then incubated with rat monoclonal antibody against msln (sc-33672, Santa Cruz) at 4°C for more than 16 hours. After washing, the second antibody (g1210-2-a, Servicebio)

(8) CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapyNature communicationsFebruary 9, 2021Rodriguez-Garcia A, Lynn RC, Poussin M, Eiva MA, Shaw LC, O'Connor RS, Minutolo NG, Casado-Medrano V, Lopez G, Matsuyama T, et al.

(9) Chimeric antigen receptor T cells targeting PD-L1 suppress tumor growthBiomarker researchJanuary 1, 2020Qin L, Zhao R, Chen D, Wei X, Wu Q, Long Y, Jiang Z, Li Y, Wu H, Zhang X, et al.

(10) A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific ImmunityCancer immunology researchNovember 1, 2019Ye S, Cohen D, Belmar NA, Choi D, Tan SS, Sho M, Akamatsu Y, Kim H, Iyer R, Cabel J, et al.

(11) Capture of mesothelioma cells with 'universal' CTC-chipOncology lettersFebruary 1, 2018Yoneda K, Chikaishi Y, Kuwata T, Ohnaga T, Tanaka F.

(12) Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biologyScientific reportsMarch 3, 2016Tatzel K, Kuroki L, Dmitriev I, Kashentseva E, Curiel DT, Goedegebuure SP, Powell MA, Mutch DG, Hawkins WG, Spitzer D.

(13) Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical ApplicationsJournal of biomedical nanotechnologyJuly 1, 2015Prantner AM, Turini M, Kerfelec B, Joshi S, Baty D, Chames P, Scholler N.

(14) Mesothelial cells: a cellular surrogate for tissue engineering of corneal endotheliumInvestigative ophthalmology & visual scienceAugust 19, 2014Lachaud CC, Soria F, Escacena N, Quesada-Hernández E, Hmadcha A, Alió J, Soria B.

(15) EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiationCell death & diseaseJune 26, 2014Lachaud CC, López-Beas J, Soria B, Hmadcha A.

(16) PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancerPloS oneJanuary 1, 2014Guo Z, Wang X, Cheng D, Xia Z, Luan M, Zhang S.anti-mouse IgG antibody (eBioscience). Staining with commercially available mouse anti-mesothelin IgG (sc-33672; Santa Cruz Biotechnology, Dallas, Texas) plus secondary antibody or secondary antibody alone was used

(17) Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model systemPloS oneJanuary 1, 2012Fredebohm J, Boettcher M, Eisen C, Gaida MM, Heller A, Keleg S, Tost J, Greulich-Bode KM, Hotz-Wagenblatt A, Lathrop M, et al.retrieved with PBS supplemented with 10% proteinase K. IgG1 antibodies against mesothelin K1 (Cat. sc-33672, Santa Cruz Biotechnology, Heidelberg, Germany) and cytokeratin 19 (clone RCK108, Code-Nr. M 0888, DakoCytomation,

(18) Mannose receptor (MR) engagement by mesothelin GPI anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibodyPloS oneJanuary 1, 2011Dangaj D, Abbott KL, Mookerjee A, Zhao A, Kirby PS, Sandaltzopoulos R, Powell DJ Jr, Lamazière A, Siegel DL, Wolf C, et al.

(19) Circulating mesothelin protein and cellular antimesothelin immunity in patients with pancreatic cancerClinical cancer research : an official journal of the American Association for Cancer ResearchNovember 1, 2009Johnston FM, Tan MC, Tan BR Jr, Porembka MR, Brunt EM, Linehan DC, Simon PO Jr, Plambeck-Suess S, Eberlein TJ, Hellstrom KE, et al.

(20) Normal mesothelial cell lines newly derived from human pleural biopsy explantsAmerican journal of physiology. Lung cellular and molecular physiologyJanuary 1, 0001"Pruett N, Singh A, Shankar A, Schrump DS, Hoang CD."

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Mesothelin (K1) Antibody

Mesothelin (K1) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

Citations (20)

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Mesothelin (K1) Antibody from Santa Cruz Biotechnology, Inc.

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