SCAP (9D5) Antibody sc-13553 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSCAP (9D5) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13553
Antibody TypePrimary Antibodies
Reactivityhamster
Clone9D5
Quantity200 µg/ml
ApplicationsWB, IP
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
TargetSCAP
IsotypeIgG2b

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) SESN2 maintains cartilage homeostasis by SREBP1-mediated lipid metabolism during osteoarthritis progressioniScienceAugust 15, 2025Liu Z, Jiang H, Zhang Z, Jiang R, Wang R, Li J, Li W, Tan G, Fei Y, Lv Z, et al.4°C with anti-SESN2 antibody (Proteintech, #10795-1-AP, 2–4 μg) or anti-SCAP antibody (Santa Cruz, #sc-13553, 2–4 μg) or corresponding IgG control antibody. Protein A/G magnetic beads were added and incubated

(2) Targeting PGM3 abolishes SREBP-1 activation-hexosamine synthesis feedback regulation to effectively suppress brain tumor growthSci AdvApril 18, 2025Huali Su, Yaogang Zhong, Liqing He, Feng Geng, Xinmin Yin, Yongjun Kou, Cheng-Yao Chiang, Xiaokui Mo, Yunzhou Fan, Yanwei Liu, et al.and Western blot assay. The SCAP were probed with the primary antibody of SCAP (Santa Cruz Biotechnology, #sc-13553; RRID: AB_628237) at the dilution of 1:1000. Cell proliferation and viability Cells cultured in the

(3) ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytesJournal of Biological ChemistryDecember 1, 2024Akifumi Uota, Yosuke Okuno, Atsunori Fukuhara, Shugo Sasaki, Sachiko Kobayashi, Iichiro Shimomuralysates were concentrated by TCA/acetone precipitation. The antibodies used were anti-SCAP (Santa Cruz, sc-13553), anti-SREBF1 (Santa Cruz, sc-13551), anti-ACTB (Sigma-Aldrich, A5441), anti-CLAR (Cell Signaling, 12238),

(4) Sulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradationScientific reportsMay 24, 2022Miyata S, Kodaka M, Kikuchi A, Matsunaga Y, Shoji K, Kuan YC, Iwase M, Takeda K, Katsuta R, Ishigami K, et al.

(5) CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processingMolecular metabolismMarch 1, 2022Zeng H, Qin H, Liao M, Zheng E, Luo X, Xiao A, Li Y, Chen L, Wei L, Zhao L, et al.Cell Signaling Technology (USA); rabbit anti-ACCα (sc-30212), mouse anti-FASN (sc-48357), mouse anti-SCAP (sc-13553), and rabbit anti-INSIG1 (sc-25124-R) were purchased from Santa Cruz Biotechnology (USA); rabbit anti-SCD1

(6) Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathwayAutophagyJuly 1, 2021Zheng ZG, Zhu ST, Cheng HM, Zhang X, Cheng G, Thu PM, Wang SP, Li HJ, Ding M, Qiang L, et al.

(7) DHT causes liver steatosis via transcriptional regulation of SCAP in normal weight female miceThe Journal of endocrinologyJune 28, 2021Seidu T, McWhorter P, Myer J, Alamgir R, Eregha N, Bogle D, Lofton T, Ecelbarger C, Andrisse S.

(8) Strength training protects against prostate injury in alcoholic ratsJournal of cellular physiologyMay 1, 2021Teixeira GR, Chuffa LGA, Mendes LO, Veras ASC, McCabe J, Favaro WJ, Pinheiro PFF, Amorim JPA, Martins OA, Mello-Junior W, et al.

(9) Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic ReticulumCell chemical biologyFebruary 18, 2021Esquejo RM, Roqueta-Rivera M, Shao W, Phelan PE, Seneviratne U, Am Ende CW, Hershberger PM, Machamer CE, Espenshade PJ, Osborne TF.,Santa Cruz Biotechnology,Cat#sc-40;RRID:AB_627268 Mouse monoclonal anti-SCAP,Santa Cruz Biotechnology,Cat#sc-13553;RRID:AB_628237 Mouse monoclonal anti-YY-1,Santa Cruz Biotechnology,Cat#sc-7341;RRID:AB_2257497 Mouse

(10) The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER-Golgi membrane contact sitesThe Journal of cell biologyJanuary 4, 2021Wakana Y, Hayashi K, Nemoto T, Watanabe C, Taoka M, Angulo-Capel J, Garcia-Parajo MF, Kumata H, Umemura T, Inoue H, et al.α-tubulin (T6074, clone B-5-1-2) were purchased from Sigma-Aldrich; Myc (sc-40, clone 9E10), hamster SCAP (sc-13553, clone 9D5), and HMGR (sc-271595, clone C-1) from Santa Cruz Biotechnology; SREBP1 (04–469, clone 2121)

(11) Golgi a-mannosidase II mediates the formation of vascular smooth muscle foam cells under inflammatory stressFolia histochemica et cytobiologicaJanuary 1, 2021Zha K, Ye Q.

(12) Short communication: The antilipogenic effect of trans-10,cis-12 conjugated linoleic acid in bovine mammary epithelial cells is associated with proteasome activity and ATP productionJournal of dairy scienceOctober 1, 2020Shi HB, Tai DM, Wang C, Liu JX, Loor JJ, Liu HY.

(13) Physical resistance training-induced changes in lipids metabolism pathways and apoptosis in prostateLipids in health and diseaseJanuary 29, 2020Teixeira GR, Mendes LO, Veras ASC, Thorpe HHA, Fávaro WJ, de Almeida Chuffa LG, Pinheiro PFF, Martinez FE.

(14) Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor GrowthCancer cellNovember 9, 2015Cheng C, Ru P, Geng F, Liu J, Yoo JY, Wu X, Cheng X, Euthine V, Hu P, Guo JY, et al.

(15) PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatusNature communicationsAugust 27, 2015Xu D, Wang Z, Zhang Y, Jiang W, Pan Y, Song BL, Chen Y.

(16) Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) ActivationThe Journal of biological chemistryAugust 14, 2015Miyata S, Inoue J, Shimizu M, Sato R.

(17) Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasisThe Journal of cell biologyNovember 11, 2013Huber MD, Vesely PW, Datta K, Gerace L.

(18) Digoxin and ouabain increase the synthesis of cholesterol in human liver cellsCellular and molecular life sciences : CMLSMay 1, 2009Campia I, Gazzano E, Pescarmona G, Ghigo D, Bosia A, Riganti C.

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SCAP (9D5) Antibody

SCAP (9D5) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SCAP (9D5) Antibody from Santa Cruz Biotechnology, Inc.

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