Thrombin R (ATAP2) Antibody sc-13503 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemThrombin R (ATAP2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-13503
Antibody TypePrimary Antibodies
NCBI Gene AliasesCf2r, PAR1, CF2R, TR, HTR, Par1, ThrR, PAR-1
Reactivitymouse, rat, human
CloneATAP2
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namecoagulation factor II thrombin receptor, coagulation factor II (thrombin) receptor
TargetThrombin R
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ROS disrupt COP9 signalosome-mediated ABCA1 protection and trigger its ubiquitination and degradation by cullin3 inhibiting cholesterol efflux and promoting foam cell formation in response to GPCR agonistsRedox BiologyApril 1, 2026Suresh Govatati, Chandra Sekhar Yadavalli, James G. Traylor, A. Wayne Orr, Gadiparthi N. Rao(sc-20795), anti-AT1R (sc-515884), anti-Gα12 (sc-409), anti-Gα13 (sc-293424), anti-Gab1 (sc-6292), anti-Par1 (sc-13503), anti-SRB1 (sc-67099), and anti-XO (sc-398548) antibodies were obtained from Santa Cruz Biotechnology

(2) A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasiaSci AdvOctober 31, 2025Shane D. Elliott, Paul J. Ready, Caitlin M. Wrinn, Qianqian Ma, Marina Edward, Robert F. Niescier, Iris Escobar, Jingbo Sun, Anil Kumar Ganga, Ceara K. McAtee, et al.Thermo Fisher Scientific #R960-25; SARM1, GeneTex #HL1066; RFP, Chromotek #5f8; and F2R, Santa Cruz Biotechnology #sc-13503) and secondary antibodies coupled to Alexa Fluor 488, Cy3, Cy5 (Jackson ImmunoResearch) or CF-750 (Biotium),

(3) Endothelial Protein C Receptor and Thrombomodulin Facilitate Protease-Activated Receptor 1 Cleavage at Arginine-46 by Thrombin and Activated Protein CJournal of Biological ChemistryJune 4, 2025Indranil Biswas, Mariko Kudo, Alireza R. RezaieMem-PERTM Plus (#89842) were obtained from Thermo Fisher. PE-conjugated PAR1 antibody (clone ATAP2 [#sc13503] and PE-conjugated mouse isotype control antibody [#sc2866], GAPDH antibody [#sc-47724]) were purchased

(4) Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathwayNeural regeneration researchFebruary 1, 2024Zhao C, Zhou T, Li M, Liu J, Zhao X, Pang Y, Liu X, Zhang J, Ma L, Li W, et al.Beijing, China",bs-0199R,NA,1:200 (Immunofluorescence staining) Anti-PAR1,Mouse,Santa Cruz Biotechnology,sc-13503,NA,1:200 (Immunofluorescence staining) "Anti-rabbit IgG, HRP-linked antibody",Goat,CST,7074S,NA,1:1000

(5) The USP7-STAT3-granzyme-Par-1 axis regulates allergic inflammation by promoting differentiation of IL-5-producing Th2 cellsProceedings of the National Academy of Sciences of the United States of AmericaDecember 5, 2023Kumagai J, Kiuchi M, Kokubo K, Yagyu H, Nemoto M, Tsuji K, Nagahata K, Sasaki A, Hishiya T, Onoue M, et al.and granzyme B (100 ng/mL; BioLegend, day 1 to 5) for 5 d. On day 3, Thrombin R (ATAP2) (100 ng/mL; sc-13503, Santa Cruz Biotechnology, Inc.) or SB203580 (10 μM; S1076, Selleck) was added to the culture medium.

(6) A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive RatsInternational Journal of Molecular SciencesOctober 30, 2023Yasunobu Iwata, Qinyuan Deng, Yutaka Kakizoe, Terumasa Nakagawa, Yoshikazu Miyasato, Miyuki Nakagawa, Kayo Nishiguchi, Yu Nagayoshi, Yuki Narita, Yuichiro Izumi, et al.StressMarq Biosciences Inc., Victoria, BC, Canada). Antibodies against Bax (sc-493), Bcl-2 (sc-492), PAR-1 (sc-13503), PAR-4 (sc-1666), and actin (sc-1616) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA,

(7) Effect of chimeric antigen receptor T cells against protease-activated receptor 1 for treating pancreatic cancerBMC medicineSeptember 4, 2023Hung HC, Fan MH, Wang D, Miao CH, Su P, Liu CL.lysates were prepared in a previously described manner [40]. Primary antibodies against PAR1 (ATAP2:sc-13503; Santa Cruz Biotechnology, Dallas, TX, USA), RhoA, ROCK1, glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

(8) Exostosin 1 Knockdown Induces Chemoresistance in MV3 Melanoma Cells by Upregulating JNK and MEK/ERK SignalingInternational journal of molecular sciencesMarch 13, 2023Pfeifer V, Weber H, Wang Y, Schlesinger M, Gorzelanny C, Bendas G.(BioRad) and Image Lab software v. 6.0.1 (BioRad). Antibody Thrombin R (ATAP2) (Santa Cruz biotechnology; sc-13503; 1:200 dilution) was used to detect PAR-1 expression. For BCRP detection, we used ABCG2 antibody (Santa Cruz biotechnology

(9) TRAP-induced PAR1 expression with its mechanism during AMI in a rat modelBMC cardiovascular disordersFebruary 21, 2023Wang A, Gu X, Wang C, Li Y, Deng F, Fang J, Chen N, Li Q, Tang L.primary antibody to PAR1 was procured from ABclonal (Cat No: A5641) and Santa Cruz Biotechnology (Cat No: SC13503). BacMam 2.0 gene delivery system for early endosome (Cat No: C10586, Rab5 labeled with GFP, green light)

(10) Estrogen depletion modulates aortic prothrombotic signaling in normotensive and spontaneously hypertensive female ratsMolecular and cellular endocrinologyFebruary 5, 2023Pizzato SB, Terraciano PB, Zanon P, Kuhl CP, Alves Garcez TN, Passos EP, Tirloni L, Berger M.Santa Cruz Biotechnology, Dallas, TX, USA); protease activated receptor – 1 (PAR1) – 1:500 (ATAP2 #sc-13503 – Santa Cruz Biotechnology, Dallas, TX, USA); plasminogen activator inhibitor – 1 (PAI-1) – 1:1000 (M-20

(11) A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancerBritish journal of pharmacologyNovember 1, 2022Zhao B, Wu M, Hu Z, Wang T, Yu J, Ma Y, Wang Q, Zhang Y, Chen D, Li T, et al.

(12) Cleavage-Responsive Biofactory T Cells Suppress Infectious Diseases-Associated HypercytokinemiaAdvanced science (Weinheim, Baden-Wurttemberg, Germany)September 1, 2022Kim H, Son B, Seo EU, Kwon M, Ahn JH, Shin H, Song GY, Park EJ, Na DH, Cho SW, et al.polyclonal to EPCR/CD201 antibody (ab151403, Abcam, United Kingdom), and monoclonal mouse PAR‐1 antibody (sc‐13503, Santa Cruz, USA). Characterization of PTMT‐T Cell HPLC analysis of PC‐Gla was carried out with a

(13) Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin ResistanceArteriosclerosis, thrombosis, and vascular biologyAugust 1, 2022Gnanenthiran SR, Pennings GJ, Reddel CJ, Campbell H, Kockx M, Hamilton JR, Chen VM, Kritharides L.

(14) Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein CThe Journal of experimental medicineJanuary 3, 2022Huuskonen MT, Wang Y, Nikolakopoulou AM, Montagne A, Dai Z, Lazic D, Sagare AP, Zhao Z, Fernandez JA, Griffin JH, et al.overnight at 4°C with primary antibodies including mouse anti-human PAR1, cross-reacts with mouse PAR1 (sc-13503; Santa Cruz); rabbit anti-human PAR2, cross-reacts with mouse PAR2 (ab124227; Abcam); rabbit anti-human

(15) Blood-nerve barrier disruption and coagulation system activation induced by mechanical compression injury participate in the peripheral sensitization of trigeminal neuralgiaFrontiers in molecular neuroscienceJanuary 1, 2022Zhou LX, Lin SW, Qiu RH, Lin L, Guo YF, Luo DS, Li YQ, Wang F.

(16) Expression/Activation of PAR-1 in Airway Epithelial Cells of COPD Patients: Ex Vivo/In Vitro StudyInternational journal of molecular sciencesOctober 2, 2021Montalbano AM, Chiappara G, Albano GD, Ferraro M, Di Sano C, Vitulo P, Pipitone L, Ricciardolo FLM, Anzalone G, Profita M.heat pre-treatment in antigen-retrieval solution, and mouse monoclonal thrombin R (ATAP-2) antibody sc-13503 (Santa Cruz Biotechnology, Inc., CA, USA) 1:20 overnight, with heat pre-treatment in antigen retrieval

(17) Increased activation product of complement 4 protein in plasma of individuals with schizophreniaTranslational psychiatrySeptember 22, 2021Kalinowski A, Liliental J, Anker LA, Linkovski O, Culbertson C, Hall JN, Pattni R, Sabatti C, Noordsy D, Hallmayer JF, et al.Scientific, Waltham, MA) or alternatively incubated overnight at 4 °C with primary antibody against PAR1 (sc-13503, Santa Cruz Biotechnology Inc., Dallas, TX) and PAR4 (sc-1666, Santa Cruz Biotechnology Inc., Dallas,

(18) The thrombin receptor modulates astroglia-neuron trophic coupling and neural repair after spinal cord injuryGliaSeptember 1, 2021Kim HN, Triplet EM, Radulovic M, Bouchal S, Kleppe LS, Simon WL, Yoon H, Scarisbrick IA.(MAB337),AB_2313673,1:2000 Olig2,Rabbit,Millipore (ab9610),AB_10141047,1:500 Olig2,Rabbit,Abcam (ab9610),AB_570666,1:500 PAR1,Mouse,Santa Cruz (SC-13503),AB_2101175,1:100 S100A10,Rabbit,Protein Tech (11250-1-AP),AB_2269906,1:7500 Serp1,Rabbit,Santa Cruz

(19) A KLK4 proteinase substrate capture approach to antagonize PAR1Scientific reportsAugust 9, 2021Rabinovitch E, Mihara K, Sananes A, Zaretsky M, Heyne M, Shifman J, Aharoni A, Hollenberg MD, Papo N.

(20) B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivationCancer gene therapyJune 1, 2021Giagulli C, Caccuri F, Zorzan S, Bugatti A, Zani A, Filippini F, Manocha E, D'Ursi P, Orro A, Dolcetti R, et al.μM,Selective antagonist of PAR-4,"Tocris Bioscience, Bristol, UK" "Monoclonal antibody to PAR1 (ATAP2, sc-13503)",mAb to PAR1,1 mg/ml,–,"Santa Cruz Biotechnology, Dallas, TX, USA" Different molecules used in B-cell

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Thrombin R (ATAP2) Antibody

Thrombin R (ATAP2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Thrombin R (ATAP2) Antibody from Santa Cruz Biotechnology, Inc.

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