Actin (C-2) Antibody sc-8432 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemActin (C-2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-8432
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human
CloneC-2
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Quantity200 µg/ml
Hostmouse
FormatPurified
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Gene AliasesACTA3, VSCM, ACT, HEL-176, VSCM1, Actc-1, MPFD, ASD5, ASMA, NEM1, NEM2, NEM3, PS1TP5BP1, SHPM, BRWS1, CMH11, CFTDM, ACTA, ACTSA, ACTSG, DFNA26, DFNA20, CFTD1, MMIHS5, LVNC4, ACTL3, CFTD, CMD1R, CMYP2C, CMYP2B, CMYP2A, ACTC, ACTE, ACTG
NCBI Full Gene Nameactin alpha 1, skeletal muscle, actin gamma 1, actin beta, actin alpha 2, smooth muscle, actin gamma 2, smooth muscle, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 1
TargetActin
IsotypeIgG1

Questions and Answers

Can this antibody be used for Western blotting in my experiments?

Yes, the Actin (C-2) Antibody has been shown to be effective for Western blotting applications, as evidenced by its use in various studies, including those that specifically mention its application in detecting β-actin levels in protein samples (, , ).

What species does this antibody react with?

The Actin (C-2) Antibody is reactive with multiple species, including human, mouse, and rat, making it suitable for a variety of biological studies across these organisms.

Is this antibody suitable for immunofluorescence applications?

Yes, the Actin (C-2) Antibody has been utilized in immunofluorescence applications, as indicated by its inclusion in studies that assess cellular localization and expression of actin in various cell types (, ).

How does this antibody perform in immunoprecipitation assays?

The Actin (C-2) Antibody has been successfully used in immunoprecipitation assays, which is critical for studying protein-protein interactions and validating the presence of actin in complex biological samples ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Homocysteine-induced endothelial dysfunction through mediating endoplasmic reticulum stressJ Int Med ResAugust 1, 2026Xiaoxue Zhang, Shengtao Xiong, Liang Long, Yue Xuan, Hongjing You, Yue Xu, Minyi Zhangglyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Proteintech, 60004-1-Ig, 1:10,000), or β-actin (Santa Cruz, sc-8432, 1:1000) at 4°C overnight. After incubation with appropriate horseradish peroxidase (HRP)–conjugated

(2) A Potent and Selective Quinolone-Based PTPN22 Inhibitor with Improved Immunotherapeutic ActivityJ Med ChemJuly 23, 2026Jianping Lin, Brenson A. Jassim, Yunpeng Bai, Zihan Qu, Frederick Nguele Meke, Jiajun Dong, Li Wu, Benjamin Babalola, Jingmei Yu, Haoran Zhang, et al.(T202/Y204) (4370) were purchased from Cell Signaling Technology. Anti-VCP (sc-57492) and anti-ACTIN (sc-8432) antibodies were purchased from Santa Cruz Biotechnology. Animal Study All the in vivo studies were

(3) Protein kinase CK2α' as a dual modulator of neuroimmune signaling and synaptic dysfunction in tauopathyTransl NeurodegenerJuly 9, 2026Angel White, Peter Gavrilyuk, Persephone Gu, Rafael Falcon-Moya, Reid Thurston, Amal Fickak, Nicholas B. Rozema, Prarthana Keshavaram, Scott Vermilyea, Riley Schlichte, et al.anti-Tau-5 (1:1000; Abcam, ab80579), mouse anti-Actin (1:500; Santa Cruz Biotechnology, Dallas, TX, sc-8432), and mouse anti-GAPDH (1:5000; Santa Cruz Biotechnology, sc-365062). Cytokine proteome profiling Cytokine

(4) Serum Starvation Promotes the Proteolysis of OGT by Activating AMPK and the CUL1/SKP1/SKP2 E3 Ubiquitin Ligase in 3T3-L1 CellsBiomolecules & TherapeuticsJuly 1, 2026Hoang Hai Ngo, Dang Quynh Le, Le Ba Nam, Young-Sam Keumwere purchased from Cell Signaling Technology (Beverly, MA, USA). Antibodies against actin (Cat. No. sc-8432) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Antibody against phospho-OGT Thr444

(5) Therapeutic activity of a hematopoietic stem cell-delivered cell-penetrating frataxin in Friedreich’s ataxia modelsCell Reports MedicineJune 16, 2026Jeffrey Pido-Lopez, Shefta E Moula, Enas Shaban, Konstantinos Stamatiou, Bethan J. Critchley, Thomas E. Whittaker, Stina Svensson, Sara Anjomani-Virmouni, Ester Kalef-Ezra, Lucinda Carr, et al.antibody,Santa Cruz Biotechnology,sc-166574; RRID:AB_2107296 Mouse anti-actin (C-2),Santa Cruz,Cat#sc-8432; RRID:AB:626630 Mouse anti-beta III tubulin [2G10],Abcam,Cat# ab78078; RRID:AB_2256751 Mouse anti-GAPDH

(6) Metabolic Endotoxemia Amplifies Estrogen Signaling Through Stromal Crosstalk in Obesity-Associated Breast CancerInt J Mol SciMay 13, 2026Emmy Drai, Daniela Nahmias Blank, Esther Hermano, Adi Yifrach, Ofer Chen, Ofra Maimon, Aron Popovtzer, Tamar Peretz, Amichay Meirovitz, Michael Elkin(NB100-1596, Novus Biologicals, Centennial, CO, USA), anti-TNFα (AF-410-SP, R&D Systems), anti-Actin (C-2) (sc-8432, Santa Cruz, Dallas, TX, USA) and anti-GAPDH (EnCor Biotechnology Inc., Gainesville, FL, USA). Immunoblotting.

(7) Establishing the first Afro-Caribbean breast cancer cell lines reveals ECM pathway enrichment and distinctive drug sensitivitiesScientific ReportsMay 6, 2026Shannique Clarke, Isabella Allen, Jovanka Ravix, Maycon Marção, Felipe Carcanholo, Albert Doughan, Alex Sanchez-Covarrubias, Derria Cornwall, Sharon Harrison, Claude-Henry Volmar, et al.pP53 (9286t), P53 (48818 s), MAPK (4370 T) and vimentin (5741 s) (Cell Signalling Technology); ACTIN (sc-8432) pRb (sc-271930) and N-cadherin (sc 53488) (Santa Cruz Biotechnology, San Diego, CA); Rb (554136) (BD

(8) Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cellsCellMay 1, 2026Peng Lyu, Gaurav Agarwal, Chun-Jie Guo, Adam Sychla, Wallace Bourgeois, Tianyi Ye, Chen Weng, Mateusz Antoszewski, Samantha Joubran, Alexis Caulier, et al.Alexa Fluor™ 488",Invitrogen,A-11034 HOXA9 Rabbit mAb,ABclonal,A19257 Actin Antibody (C-2),Santa Cruz,sc-8432 vinculin Antibody (7F9),Santa Cruz,sc-73614 SFRS2 Polyclonal antibody,Proteintech,20371-1-AP HNRNPA1

(9) S6K1 overexpression enhances autophagy in breast cancer cells by inducing the translation of CLUChinese Medical JournalApril 20, 2026Xingmei Shu, Ranjiaxi Wang, Yan Liu, Xiaoqian Shi, Yuhao Liu, Yinan Chen, Jinming Shi, Mingyang Liu, Yongmei Song, Dan Liantibodies used included those against light chain 3 (LC3, 1:1000, L8918, Sigma–Aldrich), actin (1:4000, sc-8432, Santa Cruz Biotechnology, Santa Cruz, CA, USA), S6K1 (1:3000, 2708S, Cell Signaling Technology, Boston,

(10) Rosuvastatin attenuates tubulointerstitial fibrosis by targeting the HOXA13 USAG1 BMP7 pathwayScientific ReportsApril 20, 2026Donghwan Oh, Hyo Jeong Kim, Seok-hyung Kim, Soo Hyun Kim, Tae Yeon Kim, Hoon Young Choi, Hyunwook Kim, Hyung Jong Kim, Hyeong Cheon ParkDanvers, MA, USA), α-tubulin (1:10000, Abcam, #ab15246, Cambridge, UK), and actin (1:10000, Santa Cruz, #sc-8432, Dallas, TX, USA). Immunostaining was performed using chemiluminescent reagents (SuperSignal West Pico

(11) Immunohistochemical and western blot expression of MMPs, TIMPs, and cytokeratin 10 in feline squamous cell carcinomaFront Vet SciApril 10, 2026Paul Tutu, Gennaro Altamura, Florentina Daraban Bocaneti, Ozana Maria Hritcu, Aurelian-Sorin Pasca, Mihaela Anca Dascalu, Loredana Horodincu, Oana Irina Tanase, Mihai Mares, Giuseppe Borzacchiello(housekeeping protein), membranes were stripped and incubated with mouse anti-β-actin antibody (C-2: sc-8432, Santa Cruz) at a 1:500 dilution. Densitometric quantification of proteins was performed using Image Lab software

(12) The c-Abl-RIPK3 Axis Drives Mitochondrial Dysfunction and Impaired Mitophagy in Gaucher Disease ModelsAntioxidants (Basel)April 9, 2026Cristian M. Lamaizon, Renatta Tironi-Hernández, Nohela B. Arévalo, Sebastián D. Ahumada, Daniela A. Gutiérrez, Laura Brito-Fernández, Andrea del Campo, Silvana Zanlungo, Alejandra R. Álvarez[Santa Cruz Biotechnology, Dallas, TX, USA, #sc-32233], anti-actin antibody [Santa Cruz Biotechnology, Dallas, TX, USA, #sc-8432]), all diluted 1:1000 in 3% BSA or NFDM prepared in TBS-T. After incubation with the primary antibody,

(13) Downregulation of the Transglutaminase 2-NF-κB Inflammatory Axis by a Fusion Protein of Cementoin and Secretory Leukocyte Protease Inhibitor Reduces Corneal AngiogenesisInt J Mol SciApril 2, 2026Juan Pablo Salica, María Constanza Potilinski, Gustavo Ortiz, Paulo C. Maffia, Diego Guerrieri, Eduardo Chuluyan, Juan Eduardo GalloDallas, TX, USA), TG2 (rabbit, 3557S, Cell Signaling Technology, Danvers, MA, USA), and β-actin (mouse, sc-8432, Santa Cruz Biotechnology, Dallas, TX, USA) used as a loading control. After washing, membranes were

(14) Cocaine Upregulates Microglial Lipid Droplet Formation Through Increasing Lipid Synthesis Activity In Vitro and In VivoBiomoleculesApril 1, 2026Yan Cheng, Brooke Russell, Liam Liyang Guo, Aryan Patel, Yan Y. Sanders, Ming-Lei Guo(1:2000, Proteintech, 60283-2-Ig), p21 (1:2000, Proteintech, 28248-1-AP), and β-actin (1:2000, Santa Cruz, sc-8432 or 1:2000, Sigma, A2066). The following second antibodies were purchased from the Li-COR company: IRDye®

(15) Deletion of Core 1 β3GalT-specific molecular chaperone (Cosmc) in murine intestinal epithelia leads to major alterations in glycocalyx and tumorigenesisJournal of Biological ChemistryApril 1, 2026Tongzhong Ju, Yingchun Wang, Hikaru Nishio, Matthew R. Kudelka, Xiaodong Sun, Jianmei Wang, Junwei Zeng, Lina Song, Gizem Akkas, Volkan Adsay, et al.described and Western blot (1:500 anti-Cosmc, Santa Cruz, sc-271829; and 1:1000 anti-β-Actin, Santa Cruz, sc-8432) was performed as previously described (6). BrdU incorporation Four mice at 6-months age from each

(16) Adaptor protein supersaturation drives innate immune signaling and cell fateElifeMarch 24, 2026Alejandro Rodriguez Gama, Tayla Miller, Shriram Venkatesan, Jeffrey J Lange, Jianzheng Wu, Xiaoqing Song, William D Bradford, Malcolm Cook, Jay R Unruh, Randal Halfmann(Santa Cruz Biotechnology, sc-514414), anti-FADD (Sigma, 05–486), anti-Actin (Santa Cruz Biotechnology, sc-8432) were obtained from the indicated vendors. Structural analyses Twelve human proteins contain two DFDs,

(17) Adaptor protein supersaturation drives innate immune signaling and cell fateeLifeMarch 24, 2026Alejandro Rodriguez Rodriguez Gama, Tayla Miller, Shriram Venkatesan, Jeffrey J Lange, Jianzheng Wu, Xiaoqing Song, William D Bradford, Malcolm Cook, Jay R Unruh, Randal Halfmann(Santa Cruz Biotechnology, sc-514414), anti-FADD (Sigma, 05–486), anti-Actin (Santa Cruz Biotechnology, sc-8432) were obtained from the indicated vendors. Structural analyses Twelve human proteins contain two DFDs,

(18) Functional characterization of BAP1 mutations in genome edited cholangiocarcinoma organoids: Role in cell death and drug responsesiScienceMarch 20, 2026Wunan Mi, Shaojun Shi, Imre F. Schene, Indi P. Joore, Henk P. Roest, Sabine A. Fuchs, Luc J.W. van der Laan, Monique M.A. Verstegen,Santa Cruz Biotechnology,Cat# sc-28383; RRID: AB_626723 Anti-Beta-actin (mouse monoclonal),Santa Cruz Biotechnology,Cat# sc-8432; RRID: AB_626630 Anti-cleaved caspase-3 (rabbit polyclonal),R&D Systems,Cat# AF835; RRID: AB_2243952 Anti-pMLKL

(19) Cerebral organoid exosomes reversed behavioral deficits by repressing NLRP3 mediated neuroinflammation in stress modelsiScienceMarch 20, 2026Yuhan Duan, Shaocong Zhou, Dongao Zeng, Shuaiguang Shi, Aoying Chen, Fangzhou Du, Yue Wu, Jingwen Wang, Shuang Yu, Jingzhong ZhangM4403 TUJ1,Abcam,Cat# ab78078 FZD9,SAB,Cat# 31503 GAPDH,Protein tech,Cat# 60004-1-Ig β-actin,Santa Cruz,Cat# sc-8432 DAPI,Beyotime,Cat# C1002 ,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides,

(20) Preliminary Effects of Benralizumab in an AML Cell Model with Promyelocytic Features Expressing IL-5R: An Exploratory Proof-of-Concept StudyBiomedicinesMarch 13, 2026Giovanna Lucia Piazzetta, Silvia Di Agostino, Nadia Lobello, Annamaria Aloisio, Anna Di Vito, Jessica Bria, Andrea Filardo, Isabella Coscarella, Mariaimmacolata Preianò, Corrado Pelaia, et al.was used at a 1:1000 dilution; and anti-actin antibody (Santa Cruz Biotechnology, Dallas, TX, USA, sc-8432) was used at a 1:12,000 dilution. Antibody binding was detected using the horseradish peroxidase (HRP)-conjugated

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1/11/2022Anti-Actin Works Great Lin ChenThe antibody was used to detect actin in cultured human oral keratinocytes. It works well.

Actin (C-2) Antibody

Actin (C-2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Actin (C-2) Antibody from Santa Cruz Biotechnology, Inc.

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