PI3KCA(Tyr317) Polyclonal Antibody bs-5570R from Bioss Inc.

Product Specs
ItemPI3KCA(Tyr317) Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-5570R
Quantity100ul, 20uL
ApplicationsWB, IF, WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), WB
Concentration1ug/ul
Conjugate/TagUnconjugated
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityHuman, Mouse, Mouse, Human, Bovine
TargetPI3KCA Tyr317
IsotypeIgG
Molecular Weight117kDa
HostRabbit
Antibody TypePrimary Antibody
ImmunogenKLH conjugated Synthesised phosphopeptide derived from human PI3KCA around the phosphorylation site of Tyr317
NCBI Full Gene Namephosphoenolpyruvate carboxykinase 2, mitochondrial
NCBI Gene AliasesPEPCK-M, PEPCK, PEPCK2
ClonalityPolyclonal
ModificationsTyr317

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Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
orders@biossusa.com
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sales@biossusa.com

Company Profile

Website: www.biossusa.com

(1) Quercetin improves retinal glycolysis to slow myopia progression through orchestrating the AKT/FOXO/HK2 axisRedox BiologyMarch 31, 2026Ruixue Zhang, Miao Zhang, Yunxiao Xie, Huixia Wei, Zhaohui Yang, Ying Wen, Jiawen Hao, Yongle Du, Yuanting Yang, Xuewei Yin, et al.antibody,dilution,Lot number & Manufacturer PIK3Ca,1:1000,"bs2067R, Bioss, China" p-PIK3Ca,1:1000,"bs-5570R, Bioss, China" AKT1,1:1000,"bs0115R, Bioss, China" p- AKT1,1:1000,"bs-5194R, Bioss, China" FOXO3a,1:5000,"10849-1-AP,

(2) Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathwayPLoS OneDecember 11, 2025Ruifang Li, Yan Sun, Drolma Kelsang, Mingzhi Feng, Hanhui Cai, Jun Zhangobtained from ABclonal (A19742, A19700, and A21191, Wuhan, China), and phospho-PI3K (p-PI3K) from Bioss (bs-5570R, Beijing, China). Mouse tumor necrosis factor-α (TNF-α), mouse interleukin-1β (IL-1β), and mouse interleukin-6

(3) A food-medicine homology formulation ameliorates atherosclerosis by attenuating dyslipidemia and inflammation via the PI3K/Akt/NF-κB pathwayFront PharmacolDecember 4, 2025Yadong Zheng, Kaili Chen, Shuo Zhang, Junsong Jing, Zhihao Zhou, Junfeng Lu, Christian Holscher, Wenlong Chen, Liguo Li(ab151549) and AKT (ab8805) were obtained from Abcam (Cambridge, United Kingdom), and anti-p-PI3K (BS-5570R) was from BIOSS (Beijing, China). Additional antibodies—p-AKT (GB150002), TNF-α (GB11188), IL-6 (GB11117),

(4) An Extensive Analysis of Artemisia integrifolia Linn. on T2DM: Investigating Glycolipid Metabolism, Metabolic Profiling, and Molecular Docking for Potential Functional Food ApplicationsFoodsAugust 24, 2025Meng Liu, Fazhi Su, Yujia He, Minghao Sun, Chenxi Bai, Wensen Zhang, Biao Li, Yanping Sun, Qiuhong Wang, Haixue Kuangand p-AKT (Cat# AP1453) were acquired from ABclonal Technology Co., Ltd. (Wuhan, China). The p-PI3K (bs-5570R) antibody was provided by Bioss Co., Ltd. (Beijing, China). 2.2. Preparation and Characterization of

(5) Jujuboside B Inhibits the Proliferation and Migration of Non-Small Cell Lung Cancer H1299 Cells Through Inhibiting PI3K/Akt and Wnt/β-Catenin PathwaysCancer Manag ResJune 16, 2025Mengzhu Chen, Jian Li, Shaodan Hu, Yuhan Wang, Keju Wang, Tan WangABclonal Technology (Wuhan, China); antibodies for MMP2 (No. bs0412R), MMP9 (No. bs4593R), p-PI3K (No. bs5570R), PI3K (No. bs10657R) were got from Bioss company (Beijing, China); antibodies for p-AKT (No. mAb 4060),

(6) Total flavonoids of litchi seed inhibit breast cancer metastasis by regulating the PI3K/AKT/mTOR and MAPKs signaling pathwaysPharm BiolApril 15, 2025Xin Yang, Shoushi Liu, Ying Liu, Yuanshuo Wang, Dianxin Cui, Taijin Lan, Dan Zhu, Zhiheng Su, Erwei Hao, Lilan Qin, et al.Cell Signaling Technology; PI3K (1:1000, WL02240, Rabbit, AB_3662845) from Wanleibio; p-PI3K (1:1000, bs-5570R, Rabbit, AB_11050832) from BIOSS; N-cadherin (1:1000, 380671, Rabbit, AB_2920910) and GAPDH (1:5000,

(7) Osteoclast-derived apoptotic bodies accelerate the pathological progression of osteoarthritis via disturbing subchondral bone remodelingJ Orthop TranslatMarch 7, 2025Hongbo Ai, Ce Dou, Yutong Wu, Dongyang Zhang, Ziyang Zhang, Chao Zhang, Yuhang Xi, Ying Qu, Jiulin Tan, Pengbin Yin, et al.prevention, diagnosis and treatment of early OA. 2 Methods 2.1 Reagents Antibodies againstp-PI3K (BS-5570R), PI3K (BS-4160R), p-AKT (BS-2849R), Akt (BS-0115R), p-S6K (BS-5671R), S6K (BS-1426R), Runx2(BS-1134R),

(8) Upregulation of PD-L1 contributes to improving the apoptosis of granulosa cells via the PI3K/AKT pathway in PCOSJournal of assisted reproduction and geneticsFebruary 1, 2025Han R, Zhu Y, Zhang X, Liu X, Xia Y, Ye E, La X, Ding J.Shanghai, China), Bax (AF1270; Beyotime, Shanghai, China), PI3K (BM4107; Boster, Wuhan, China), p-PI3K (bs-5570R; Bioss, Beijing, China), AKT (AF1789; Beyotime, Shanghai, China), p-AKT (BM4721; Boster, Wuhan, China),

(9) Denervation‑induced NRG3 aggravates muscle heterotopic ossification via the ErbB4/PI3K/Akt signaling pathwayMolecular Medicine ReportsOctober 21, 2024Lin Ma, Xia Kang, Jindong Tan, Yunjiao Wang, Xiao Liu, Hong Tang, Lin Guo, Kanglai Tang, Xuting BianPBS containing 5% BSA (cat. no. BS114, Biosharp) with primary antibodies anti-PI3K (1:2,000; cat. no. bs-5570R, BIOSS), anti-phosphorylated (p)-PI3K (1:2,000; cat. no. bs-5538P, BIOSS), anti-AKT (1:2,000; cat. no.

(10) Claudin-9 (CLDN9) promotes gastric cancer progression by enhancing the glycolysis pathway and facilitating PD-L1 lactylation to suppress CD8+ T cell anti-tumor immunityCancer Pathogenesis and TherapySeptember 26, 2024Xingbin Hu, Wenhao Ouyang, Haizhu Chen, Zhihong Liu, Zijia Lai, Herui Yao(66444-1-Ig, Proteintech), phosphatidylinositol 3-kinase (PI3K) (bs-2067R, Bioss), and phospho-PI3K (bs-5570R, Bioss). Following this, the membrane was incubated with goat anti-mouse immunoglobulin G (IgG) H +

(11) Chinese Herbal Compound Xiaoliu Pingyi Recipe Inhibits the Growth of Lung Adenocarcinoma by Regulating the Tumor Vascular MicroenvironmentIntegrative Cancer TherapiesSeptember 3, 2024Fei-ran Yang, Hong-lin Li, Xi-wen Hu, Rong Fu, Xiu-rong Li, Hui-jie Li(#36169) were purchased from Cell Signaling Technology (Danvers, MA, USA), phosphor-PI3K (p-PI3K, #bs-5570R) was purchased from Bioss (Beijing, China), Ang-2 (#ab155106) was purchased from Abcam (Cambridge, UK),

(12) GluOC promotes proliferation and metastasis of TNBC through the ROCK1 signaling pathwayCancer Cell InternationalJuly 25, 2024Jiaojiao Xu, Keting Dong, Xue Bai, Miao Zhang, Qian Du, Lei Chen, Jianhong YangSOX2 (Wanleibio, WL03767), P-JAK2 (Wanleibio, WL02997), JAK2 (Wanleibio, WL02188), P-PIK3CA (Bioss, bs-5570R), PIK3CA (Bioss, bs-2067R), P-AKT (Cell Signaling Technology, #4060), AKT (Abcam, 179,463), P-CREB (Abmart,

(13) Scutellarin alleviates microglia‐mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathwayJournal of Cell Communication and SignalingJune 1, 2024Zhaoda Duan, Haolun Chen, Wei Miao, Jing He, Dongyao Xu, Zhi Qi, Li Yang, Wenji Jia, Chunyun WuAnti‐IgG, 1:1000; Protein‐tech, USA, #60225‐1‐Ig), p‐PI3K (Rabbit Anti‐IgG, 1:1000; Bioss, Beijing, #bs‐5570R), AKT (Rabbit Anti‐IgG, 1:2000; Protein‐tech, USA, #10176‐2‐AP), p‐AKT (Mouse Anti‐IgG, 1:1000; Protein‐tech,

(14) NIPBL-mediated RAD21 facilitates tumorigenicity by the PI3K pathway in non-small-cell lung cancerCommunications BiologyFebruary 20, 2024Xiaoling Xu, Ding Wang, Weizhen Xu, Huihui Li, Ning Chen, Na Li, Qifeng Yao, Jianxiang Zhong, Wei Chen, Weimin Mao(#21800-1-AP, Proteintech), PI3K antibody (#bs-2067R, Bioss, Beijing, China), phospho-PI3K (Tyr317) antibody (#bs-5570R, Bioss) and GAPDH (#KC-5G5, Aksomicks, Shanghai, China). RNA sequencing After the extraction of total

(15) Caveolin-1 promotes glioma proliferation and metastasis by enhancing EMT via mediating PAI-1 activation and its correlation with immune infiltratesHeliyonJanuary 30, 2024Zhaoxiang Wang, Gang Chen, Debin Yuan, Peizhang Wu, Jun Guo, Yisheng Lu, Zhenyu WangServicebio, China), phospho-Akt (T40067S, Abmart, China), Akt (T55561S, Abmart, China), phospho-PI3K(bs-5570R, Bioss, China), PI3K(bs-2067R, Bioss, China), PAI-1(49536S, Cell Signaling Tech., USA), Vimentin (49536S,

(16) Anticancer potential of Bacillus coagulans MZY531 on mouse H22 hepatocellular carcinoma cells via anti-proliferation and apoptosis inductionBMC complementary medicine and therapiesSeptember 13, 2023Zhao Z, Yang Q, Zhou T, Liu C, Sun M, Cui X, Zhang X.primary anti-rabbit monoclonal antibodies: β-actin (bsm-52846R, BIOSS), PI3K (bs-10657R, BIOSS), p-PI3K (bs-5570R, BIOSS), AKT (bs-0115R, BIOSS), p-AKT (bs-0876R, BIOSS), mTOR (bsm-54471R, BIOSS), p-mTOR (bs-5331R,

(17) Ze-Qi decoction inhibits non-small cell lung cancer growth and metastasis by modulating the PI3K/Akt/p53 signaling pathwayJournal of Traditional and Complementary MedicineSeptember 1, 2023Jingtao Zhang, Zifan Zhuang, Minghao Guo, Kai Wu, Qingfeng Yang, Xin Min, Wenqiang Cui, Fei Xuanti-phosphoinositide 3-kinase (anti-PI3K; 1:3000, 67071-1-Ig; Proteintech, Wuhan, China), rabbit anti-P-PI3K (1:1000, bs-5570R; Bioss, Beijing, China), mouse anti-protein kinase B (anti-AKT; 1:20000, 60203-2-Ig; Proteintech, Wuhan,

(18) Comprehensive transcriptomic profiling and mutational landscape of primary gastric linitis plasticaGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer AssociationMarch 1, 2023Liu Z, Hong LL, Zheng JS, Ling ZN, Zhang ZL, Qi YN, Zhang XY, Zhu TY, Wang JL, Han J, et al.dilution) (Proteintech Group, Inc, USA), PI3K (bs-2067R, 1:1000 dilution) (Bioss, Beijing, China), p-PI3K (bs-5570R, 1:1000 dilution) (Bioss, Beijing, China), AKT (10,176–2-AP, 1:1000 dilution) (Proteintech Group, Inc,

(19) Niaoduqing alleviates podocyte injury in high glucose model via regulating multiple targets and AGE/RAGE pathway: Network pharmacology and experimental validationFrontiers in PharmacologyFebruary 27, 2023Yipeng Fang, Yunfei Zhang, Chenxi Jia, Chunhong Ren, Xutao Zhao, Xin Zhangfrom Affinity Biosciences (Ohio, United States). Anti-phospho-PI3KCA antibody (p-PI3KTyr317, 110kD, bs-5570R) was obtained from Bioss Biotech (Beijing, China). Anti-AKT antibody (60 kD, 4691S), anti-phospho-AKT

(20) N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signalingBMC molecular and cell biologyJanuary 5, 2023Lu K, Zhou M, Wang L, Wang Y, Tang H, He G, Wang H, Tang C, He J, Wang W, et al.anti-phospho-AKT (Thr308, 1:1000, 9275 S; CST), anti-PIK3CA (1:1000, bs-2067R; Bioss), anti-phospho-PI3KCA (1:1000, bs-5570R; Bioss), anti-integrin alpha 5 (1:1000, bs-0567R; Bioss), anti-integrin beta 1 (1:1000, bs-0486R; Bioss),

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PI3KCA(Tyr317) Polyclonal Antibody from Bioss Inc.

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PI3KCA(Tyr317) Polyclonal Antibody from Bioss Inc.

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