Granzyme B Antibody (CLB-GB11)

Product Specs
ItemGranzyme B Antibody (CLB-GB11) - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNBP1-50071
ApplicationsFlow Cytometry,Flow (Intracellular),CyTOF-ready
CloneCLB-GB11
Concentration1 mg/ml
FormatTris buffered saline (TBS), pH 8.0
IsotypeIgG1
Quantity0.1 mg
ImmunogenHuman NK cell line YT-INDY-derived granzyme B
TargetGranzyme B
ClonalityMonoclonal
ReactivityHu, Pr
PurityProtein A purified
Antibody TypePrimary Antibodies
StorageStore at 4C. Do not freeze
NCBI Full Gene Namegranzyme B
NCBI Gene AliasesC11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Research AreaApoptosis
Molecular Weight31 kDa
HostMouse
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed in activated Tc cells and NK cells.

Sizes Available: 0.1 mg

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Assessing Human Treg Suppression at Single-Cell Resolution Using Mass CytometryBio ProtocAugust 20, 2025Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wingnumber: 612302, titration: 1:200) i. Anti-Granzyme B, 150Nd (Novus, clone CLB-GB11, catalog number: NBP1-50071, titration: 1:100) j. Anti-CPT1A, 152Sm (Abcam, clone 8F6AE9, catalog number: ab128568, titration: 1:100) k.

(2) Assessing Human Treg Suppression at Single-Cell Resolution Using Mass CytometryBio ProtocAugust 20, 2025Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wingnumber: 612302, titration: 1:200) i. Anti-Granzyme B, 150Nd (Novus, clone CLB-GB11, catalog number: NBP1-50071, titration: 1:100) j. Anti-CPT1A, 152Sm (Abcam, clone 8F6AE9, catalog number: ab128568, titration: 1:100) k.

(3) Single cell suppression profiling of human regulatory T cellsNat CommunFebruary 3, 2025Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wing,Thermo Fisher,Polyclonal,PA5-27650,100 149Sm,anti-Cytochrome C,Biolegend,6H2.B4,612302,200 150Nd,anti-Granzyme B,Novus,CLB-GB11,NBP1-50071,100 152Sm,anti-CPT1A,AbCam,8F6AE9,ab128568,100 157Gd,anti-T-bet,Biolegend,4B10,644802,100 161Dy,anti-VDAC1/Porin,AbCam,20B12AF2,ab14734,100 162Dy,anti-Foxp3,eBioscience,236A/E7,14-4777-82,200 164Dy,anti-CyclinB1,Standard

(4) Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint BlockadeAdvances in radiation oncologyJanuary 1, 0001"Davidson T, Zhang H, Dong H, Grams MP, Park SS, Yan Y."

(5) Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinomaGutJanuary 1, 0001"Salié H, Wischer L, D'Alessio A, Godbole I, Suo Y, Otto-Mora P, Beck J, Neumann O, Stenzinger A, Schirmacher P, et al."

(6) Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patientsMelanoma researchJanuary 1, 0001"Vera Aguilera J, Paludo J, McWilliams RR, Zhang H, Li Y, Kumar AB, Failing J, Kottschade LA, Block MS, Markovic SN, et al."

(7) A Novel PD-L1 Antibody Promotes Antitumor Function of Peripheral Cytotoxic Lymphocytes after Radical Nephrectomy in Patients with Renal Cell Carcinoma"Journal of immunology (Baltimore, Md. : 1950)"January 1, 0001"An Z, Hsu MA, Gicobi JK, Xu T, Harrington SM, Zhang H, Pavelko KD, Hirdler JB, Lohse CM, Nabavizadeh R, et al."

(8) Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity"International journal of radiation oncology, biology, physics"January 1, 0001"Lucien F, Kim Y, Qian J, Orme JJ, Zhang H, Arafa A, Abraha F, Thapa I, Tryggestad EJ, Harmsen WS, et al."

(9) CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapyJCI insightJanuary 1, 0001"Yan Y, Cao S, Liu X, Harrington SM, Bindeman WE, Adjei AA, Jang JS, Jen J, Li Y, Chanana P, et al."

(10) Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T CellsImmunityJanuary 1, 0001"Bengsch B, Ohtani T, Khan O, Setty M, Manne S, O'Brien S, Gherardini PF, Herati RS, Huang AC, Chang KM, et al."162Dy",Fluidigm,RRID:AB_2687650 Cat#3162011A "Anti-Granzyme B, clone CLB-GB11",Novus,RRID:AB_10012261 Cat#NBP1-50071 "Anti-Granzyme K, clone GM6C3",Santa Cruz,RRID:AB_2263772 Cat#sc-56125 "Anti-Granzyme M, clone 4B2G4",Bovenschen

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